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The map label for this gene is galE [H]

Identifier: 150007165

GI number: 150007165

Start: 603313

End: 604353

Strand: Reverse

Name: galE [H]

Synonym: BDI_0510

Alternate gene names: 150007165

Gene position: 604353-603313 (Counterclockwise)

Preceding gene: 150007166

Following gene: 150007156

Centisome position: 12.56

GC content: 48.7

Gene sequence:

>1041_bases
ATGAAAAAGAAGATTTTAGTAGCGGGCGGAACCGGTTATATCGGCTCACACACCACAGTAGAATTGCAGAACGCCGGATA
TGAGGTAGTCATTATCGACGATTTGTCAAACTCGAATATCGAGGTGCTCGATGGTATCGAGAAAATCACGGGCATCCGTC
CGGAGTTTATCCAATTGGATCTAAAGGATAAGGAAGGTACTCGCAAGGCATTGGAAGCTCATCCGGGCATCAAAGGCATT
ATCTTGTTCGCCGCTAGCAAGGCGGTAGGAGAATCCGTACAGCAGCCTTTGAAGTATTATCGCAATAATATTGTCACTTT
GGTGAACTTGTTGGAGATGATGCCTGAATTCAATATCGAAGGTATCGTATTCTCTTCCTCTTGTACGGTATACGGACAAC
CGGATCCGGAGAACTTGCCGGTAACCGAGAATGCCCCGATCAAACCCGCTATGTCTCCTTATGGAAACACGAAGCAGATC
AACGAGGAGATTATCCGGGATACGATCCATGCGGGAGCGCCTTTCAAGAGTATCATCTTGCGCTACTTCAACCCGATAGG
CGCTCACCCAAGCGCAGAGATCGGCGAGTTGCCAAATGGTGTTCCCCAGAACTTGATCCCGTACTTGACACAGACGGCTA
TGGGTATCCGCAAGGAATTAAGCGTATTCGGCGATGATTATGATACGGCAGACGGCTCTTGCATCCGTGACTATATCAAT
GTCGTAGACTTGGCGAAAGCGCATGTAATCGCTATGGACCGTATGCTTGAGAATAAGTCTGATGAGCATATCGAGATATT
CAACCTAGGTACCGGCAATGGTGTTTCTGTCCTTGAACTGATCAATACCTTCGAGCAGACAACAGGCGTTAAGGTTCCGC
ACAAGATCGTGGGCCGTCGTGAAGGTGATATCGAGAAGGTATGGGCCAATCCGGAGCACGCGAATAAGGTATTAGGCTGG
ACCGCCAAGGAGACTTTAGCCGACACCCTGCAATCCGCATGGAACTGGCAGAAACGTTTGAGAGAACGTGGCATCCAGTA
A

Upstream 100 bases:

>100_bases
AAAGGCACTCCTATCGCCTTGATAACGGCCGGTTTGCTAGCTATGGCTTTTATGGGATTCTCGGGTATCGTATAACAAAC
TTATCTAAATGAACACTAGA

Downstream 100 bases:

>100_bases
ATAACACAAAAAAGAGGCCGTATCTGATAGCGCTTAGCTAAGATATGGCCTTTTTTATATCCTTATATCTACAAGTATTT
CTCTAAGATCTCAAGAACTT

Product: putative UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDGIEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGI
ILFAASKAVGESVQQPLKYYRNNIVTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQI
NEEIIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSVFGDDYDTADGSCIRDYIN
VVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELINTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGW
TAKETLADTLQSAWNWQKRLRERGIQ

Sequences:

>Translated_346_residues
MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDGIEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGI
ILFAASKAVGESVQQPLKYYRNNIVTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQI
NEEIIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSVFGDDYDTADGSCIRDYIN
VVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELINTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGW
TAKETLADTLQSAWNWQKRLRERGIQ
>Mature_346_residues
MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDGIEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGI
ILFAASKAVGESVQQPLKYYRNNIVTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQI
NEEIIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSVFGDDYDTADGSCIRDYIN
VVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELINTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGW
TAKETLADTLQSAWNWQKRLRERGIQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=45.7971014492754, Blast_Score=316, Evalue=2e-86,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=45.7971014492754, Blast_Score=316, Evalue=2e-86,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=45.7971014492754, Blast_Score=316, Evalue=2e-86,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=44.6428571428571, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71982035, Length=342, Percent_Identity=43.2748538011696, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=43.0232558139535, Blast_Score=280, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6319493, Length=338, Percent_Identity=44.9704142011834, Blast_Score=297, Evalue=2e-81,
Organism=Drosophila melanogaster, GI19923002, Length=341, Percent_Identity=44.8680351906158, Blast_Score=301, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38259; Mature: 38259

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDGIEKITGIRPEFIQLD
CCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEE
LKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNIVTLVNLLEMMPEFNIE
CCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQINEEIIRDTIHAGAPFKSIIL
EEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
RYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSVFGDDYDTADGSCIRDYIN
HHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELINTFEQTTGVKVPHKIVGRR
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
EGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRLRERGIQ
CCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDGIEKITGIRPEFIQLD
CCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEE
LKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNIVTLVNLLEMMPEFNIE
CCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQINEEIIRDTIHAGAPFKSIIL
EEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
RYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSVFGDDYDTADGSCIRDYIN
HHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELINTFEQTTGVKVPHKIVGRR
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
EGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRLRERGIQ
CCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]