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The map label for this gene is yqjC [H]

Identifier: 150006833

GI number: 150006833

Start: 175413

End: 175823

Strand: Reverse

Name: yqjC [H]

Synonym: BDI_0164

Alternate gene names: 150006833

Gene position: 175823-175413 (Counterclockwise)

Preceding gene: 150006834

Following gene: 150006832

Centisome position: 3.65

GC content: 42.82

Gene sequence:

>411_bases
ATGGAACTTACACATATCGAACATTTAGGTATCGCAGTGAAGAGTATCGAGGCTTGTTTACCCTATTATGAAGGCGTTCT
TGGATTAAAATGCTACAATATCGAAGTAGTAGCAGACCAAAAAGTAAAAACCGCATTTTTCAAGGTAGGACAGACTAAGA
TTGAATTACTAGAGCCGACCAGCGAAGATAGCACGATTGCGAAATTTATCGAGAAAAAAGGTGAAGGTATCCACCATATC
GCATTTGCGGTACCTGATGTACAGGCAGCTTTGAACGAGGCTGAGGAAAAAGGCGTTAAATTAATCGATAAAGCTCCCCG
TGGTGGCGCGGAAGGCTTGAACATCGCTTTCCTTCACCCGAAATCAACTTGCAGCGTATTGACAGAACTTTGCATGCCGG
GCAACAAATAA

Upstream 100 bases:

>100_bases
GGAGATAAAAACAAAAAATTATTTCCTCATTCATAAAAAGTAGTGTACATTTGCACACAATAGAAACAAACATTTACTAA
ATCTTTAAATTATTATTGAC

Downstream 100 bases:

>100_bases
TTAATCCGTTCATTTCTAACAACAAATCAAAATACAATGAGTAACCAGCTTGAAAAAGTAAAAGAGCTCATCGCACTTCG
TGAGCAAGCTCGTTTGGGTG

Product: lactoylglutathione lyase and related protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTAFFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHI
AFAVPDVQAALNEAEEKGVKLIDKAPRGGAEGLNIAFLHPKSTCSVLTELCMPGNK

Sequences:

>Translated_136_residues
MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTAFFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHI
AFAVPDVQAALNEAEEKGVKLIDKAPRGGAEGLNIAFLHPKSTCSVLTELCMPGNK
>Mature_136_residues
MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTAFFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHI
AFAVPDVQAALNEAEEKGVKLIDKAPRGGAEGLNIAFLHPKSTCSVLTELCMPGNK

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=131, Percent_Identity=34.3511450381679, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506387, Length=129, Percent_Identity=35.6589147286822, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14777; Mature: 14777

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTAFFKVGQTKIELLEPT
CCCCHHHHHHHHHHHHHHHHHHHCCHHCEEEEEEEEEECCHHHHHHHHCCCCEEEEECCC
SEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDKAPRGGAEGLNIAFLHP
CCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECC
KSTCSVLTELCMPGNK
CHHHHHHHHHCCCCCC
>Mature Secondary Structure
MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTAFFKVGQTKIELLEPT
CCCCHHHHHHHHHHHHHHHHHHHCCHHCEEEEEEEEEECCHHHHHHHHCCCCEEEEECCC
SEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDKAPRGGAEGLNIAFLHP
CCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEECC
KSTCSVLTELCMPGNK
CHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]