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The map label for this gene is argC

Identifier: 150006742

GI number: 150006742

Start: 72601

End: 73569

Strand: Reverse

Name: argC

Synonym: BDI_0068

Alternate gene names: 150006742

Gene position: 73569-72601 (Counterclockwise)

Preceding gene: 150006743

Following gene: 150006741

Centisome position: 1.53

GC content: 48.19

Gene sequence:

>969_bases
ATGATTAAATGCGGAATTATAGGCGGAGCGGGTTACACGGCGGGTGAATTGATCCGCCTGCTCCTAAACCACCCTGATGC
CGAGCTTACATTTATAAACAGTAGCAGTAACGCCGGTAACAAGATCACGGACGTGCATGGTGGTCTTTATGGCGAGACGG
ATTTGGTGTTCACCAGCGAGTTGCCGTTAGATAGCATCGACCTTCTGTTCTTCTGTACCGCTCATGGCGATACGAAAAAG
TTCATGGAGAACCACACGGTTCCCGAGAACGTGAAGATTATCGACCTGAGCATGGACTACCGGATCGAAGGCCCGGAGCA
CGATTTCGTGTACGGCCTGCCGGAATTAAACCGCCGCCGAATTTGCAACGCCCGGCATATAGCGAACCCCGGTTGTTTCG
CTACTTGCATCCAATTGGGCGTATTGCCGTTGGCGAAGCACTTGATGCTGAATTCCGACTTGCATGTCAATGCCATCACG
GGTTCTACGGGAGCGGGCGTGAAGCCTTCTTCCACCTCTCACTTTAGCTGGCGCAACGACAACATATCAATCTATAAGCC
TTTTACGCATCAGCACTTGGCCGAGATCAACCAGAGCTTGAGCCAGTTGCAGAAGAGCTATTCAAGCCGGATCAACTTCA
TCCCCGTACGCGGTAATTTCTCCCGTGGTATATTCGCCACGACATACATCGATTGCAAGATTGACTTGGTGGAGATCCGA
CGTATTTATGAGGAATATTATGATGATCACAGCTTCACGTTTATCACTGATAAGAACCCGGATTTGAAACAAGTGGTAAA
TACGAATAAATGCTTGATCCACTTACAGAAAATAGATGATAAGCTTCTTATTATCTCTATGATCGATAACTTATTGAAGG
GTGCTAGCGGCCAAGCGGTCCACAACATGAACTTATTGTTCGGGTTGGAGGAGACGGTTGGCTTACACTTAAAACCCTCC
GCGTTTTAA

Upstream 100 bases:

>100_bases
AGATGCAGAAAGGCTGGACCGCCGAGGACGCTAAGGGCTTCATCAAGGTTCTTTCTACTCCGTTGCGTGTTTATTATACG
AACCATAAAGACGAAGAGAT

Downstream 100 bases:

>100_bases
AAAATACTATAAAGATGAATTTATTCGACGTATATCCATTATTTAATATAGAGATCGTACAAGGCAAGGGATGTCATGTA
TGGGATAGCGAGGGAAACGA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITDVHGGLYGETDLVFTSELPLDSIDLLFFCTAHGDTKK
FMENHTVPENVKIIDLSMDYRIEGPEHDFVYGLPELNRRRICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAIT
GSTGAGVKPSSTSHFSWRNDNISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRGNFSRGIFATTYIDCKIDLVEIR
RIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQKIDDKLLIISMIDNLLKGASGQAVHNMNLLFGLEETVGLHLKPS
AF

Sequences:

>Translated_322_residues
MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITDVHGGLYGETDLVFTSELPLDSIDLLFFCTAHGDTKK
FMENHTVPENVKIIDLSMDYRIEGPEHDFVYGLPELNRRRICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAIT
GSTGAGVKPSSTSHFSWRNDNISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRGNFSRGIFATTYIDCKIDLVEIR
RIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQKIDDKLLIISMIDNLLKGASGQAVHNMNLLFGLEETVGLHLKPS
AF
>Mature_322_residues
MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITDVHGGLYGETDLVFTSELPLDSIDLLFFCTAHGDTKK
FMENHTVPENVKIIDLSMDYRIEGPEHDFVYGLPELNRRRICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAIT
GSTGAGVKPSSTSHFSWRNDNISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRGNFSRGIFATTYIDCKIDLVEIR
RIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQKIDDKLLIISMIDNLLKGASGQAVHNMNLLFGLEETVGLHLKPS
AF

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=350, Percent_Identity=31.4285714285714, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320913, Length=329, Percent_Identity=32.5227963525836, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PARD8 (A6L849)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301485.1
- ProteinModelPortal:   A6L849
- SMR:   A6L849
- STRING:   A6L849
- GeneID:   5305159
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0068
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   DTKKFME
- ProtClustDB:   PRK00436
- BioCyc:   PDIS435591:BDI_0068-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 35980; Mature: 35980

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS01224 ARGC; PS00443 GATASE_TYPE_II

Important sites: ACT_SITE 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITDVHGGLYGETDLVFTSE
CEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEECC
LPLDSIDLLFFCTAHGDTKKFMENHTVPENVKIIDLSMDYRIEGPEHDFVYGLPELNRRR
CCCCCEEEEEEEECCCCHHHHHHCCCCCCCEEEEEEEECEEECCCCCCEEECCCCCCHHH
ICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAITGSTGAGVKPSSTSHFSWRND
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECC
NISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRGNFSRGIFATTYIDCKIDLVEIR
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEEEHHHHHH
RIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQKIDDKLLIISMIDNLLKGASGQAV
HHHHHHCCCCCEEEEECCCCCHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHCCCCCCEE
HNMNLLFGLEETVGLHLKPSAF
EEEEEEEECHHHHCEEECCCCC
>Mature Secondary Structure
MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITDVHGGLYGETDLVFTSE
CEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEECC
LPLDSIDLLFFCTAHGDTKKFMENHTVPENVKIIDLSMDYRIEGPEHDFVYGLPELNRRR
CCCCCEEEEEEEECCCCHHHHHHCCCCCCCEEEEEEEECEEECCCCCCEEECCCCCCHHH
ICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAITGSTGAGVKPSSTSHFSWRND
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECC
NISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRGNFSRGIFATTYIDCKIDLVEIR
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEEEHHHHHH
RIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQKIDDKLLIISMIDNLLKGASGQAV
HHHHHHCCCCCEEEEECCCCCHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHCCCCCCEE
HNMNLLFGLEETVGLHLKPSAF
EEEEEEEECHHHHCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA