Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 150006741

GI number: 150006741

Start: 71459

End: 72586

Strand: Reverse

Name: argD [H]

Synonym: BDI_0067

Alternate gene names: 150006741

Gene position: 72586-71459 (Counterclockwise)

Preceding gene: 150006742

Following gene: 150006740

Centisome position: 1.51

GC content: 48.23

Gene sequence:

>1128_bases
ATGAATTTATTCGACGTATATCCATTATTTAATATAGAGATCGTACAAGGCAAGGGATGTCATGTATGGGATAGCGAGGG
AAACGAGTACCTCGACTTATATGGCGGCCATGCCGTGATCTCGGTGGGGCACAGCCACCCTACTTACGTAAAGGCGATTA
CCGAGCAGGTAAATAAATTAGGCTTTTACTCGAACTCGGTTATCAATAGCTTGCAACAAAAATTAGCGGATAAGCTAGGG
AAGGCTTCCGGCTACGATGATTATTCGTTGTTCTTGATCAACTCCGGAGCGGAGGCGAACGAGAACGCGTTAAAGCTCGC
CTCTTTTCATAACGGGAAGAAGCGGGTGATCGCATTCAAGCACGCCTTTCATGGACGTACCTCCGCCGCCGTTCGTGTCA
CGGATAACCCGAAGATCATCGCTCCGGTAAATGAGGATCTAGCGGTTACTTATCTTCCATTGAACGACGCTTCCGCCGTA
GAGGAAGAGTTGAAGAAGGGGGATGTATCGTCCGTGATCATCGAAGGTATCCAAGGTGTAGGTGGCATCCAATTGCCAAC
GGATGATTTTATGCGTGAGTTACGCAACCTGTGTACGACTTATGATGCCTGTCTGATCTTGGATGAGATTCAATCCGGAT
ATGGAAGAAGCGGTAAATTCTTCGCACATCAATATGCCGGTATCAAGCCGGATTTGATCTCGGTAGCGAAAGGTATCGCC
AATGGCTTCCCGATGGGTGGGTTATTGATCAGCCCGAAATTCAAGCCGGTTTATGGTATGCTCGGCACTACTTTCGGCGG
TAACCATTTGGCTTGCGCAGCCGCTATCGCCGTTCTCGATATTATGGAAGACGAGCGTTTGATTGATAACGCGGCGAAAG
TGGGTGCCTATTTATTGGATGAGCTTCATAAACTTCCGGGTATCAAGGAAATTCGGGGCCGTGGTTTGATGATCGGTATC
GAGTTCGAGGAATCTATCAAGGAAGTACGTAGCAAACTTCTCTTTGAGGAGAAAGTGTTCACGGGCGTAGCCGGAACCCA
TACGATCCGTCTGCTTCCTCCGCTTTGCTTGACGATGGATGAGGCCAAGGAATTTATCCGTCGCTTCAAGAAAGTCCTAA
ACGCTTAA

Upstream 100 bases:

>100_bases
CTAGCGGCCAAGCGGTCCACAACATGAACTTATTGTTCGGGTTGGAGGAGACGGTTGGCTTACACTTAAAACCCTCCGCG
TTTTAAAAAATACTATAAAG

Downstream 100 bases:

>100_bases
TTGTTCTTTATTTCATAAAAAGGGAGGATGTCTGAATTAGTGTCCTCCTTTTTTCCATTCCTCCCCAACAGCGACGTAAA
TTAAGTATCACCCTTTGTCA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNLFDVYPLFNIEIVQGKGCHVWDSEGNEYLDLYGGHAVISVGHSHPTYVKAITEQVNKLGFYSNSVINSLQQKLADKLG
KASGYDDYSLFLINSGAEANENALKLASFHNGKKRVIAFKHAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDASAV
EEELKKGDVSSVIIEGIQGVGGIQLPTDDFMRELRNLCTTYDACLILDEIQSGYGRSGKFFAHQYAGIKPDLISVAKGIA
NGFPMGGLLISPKFKPVYGMLGTTFGGNHLACAAAIAVLDIMEDERLIDNAAKVGAYLLDELHKLPGIKEIRGRGLMIGI
EFEESIKEVRSKLLFEEKVFTGVAGTHTIRLLPPLCLTMDEAKEFIRRFKKVLNA

Sequences:

>Translated_375_residues
MNLFDVYPLFNIEIVQGKGCHVWDSEGNEYLDLYGGHAVISVGHSHPTYVKAITEQVNKLGFYSNSVINSLQQKLADKLG
KASGYDDYSLFLINSGAEANENALKLASFHNGKKRVIAFKHAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDASAV
EEELKKGDVSSVIIEGIQGVGGIQLPTDDFMRELRNLCTTYDACLILDEIQSGYGRSGKFFAHQYAGIKPDLISVAKGIA
NGFPMGGLLISPKFKPVYGMLGTTFGGNHLACAAAIAVLDIMEDERLIDNAAKVGAYLLDELHKLPGIKEIRGRGLMIGI
EFEESIKEVRSKLLFEEKVFTGVAGTHTIRLLPPLCLTMDEAKEFIRRFKKVLNA
>Mature_375_residues
MNLFDVYPLFNIEIVQGKGCHVWDSEGNEYLDLYGGHAVISVGHSHPTYVKAITEQVNKLGFYSNSVINSLQQKLADKLG
KASGYDDYSLFLINSGAEANENALKLASFHNGKKRVIAFKHAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDASAV
EEELKKGDVSSVIIEGIQGVGGIQLPTDDFMRELRNLCTTYDACLILDEIQSGYGRSGKFFAHQYAGIKPDLISVAKGIA
NGFPMGGLLISPKFKPVYGMLGTTFGGNHLACAAAIAVLDIMEDERLIDNAAKVGAYLLDELHKLPGIKEIRGRGLMIGI
EFEESIKEVRSKLLFEEKVFTGVAGTHTIRLLPPLCLTMDEAKEFIRRFKKVLNA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=30.9278350515464, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI13994255, Length=419, Percent_Identity=28.4009546539379, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=28.0193236714976, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=29.2383292383292, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=31.7880794701987, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=377, Percent_Identity=28.9124668435013, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=28.2555282555283, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI188536080, Length=426, Percent_Identity=27.2300469483568, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI38679950, Length=426, Percent_Identity=27.2300469483568, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI38679946, Length=426, Percent_Identity=27.2300469483568, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1788044, Length=375, Percent_Identity=35.4666666666667, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789759, Length=375, Percent_Identity=35.4666666666667, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI145693181, Length=392, Percent_Identity=33.9285714285714, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789016, Length=352, Percent_Identity=35.7954545454545, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787560, Length=331, Percent_Identity=34.7432024169184, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786349, Length=293, Percent_Identity=28.3276450511945, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786991, Length=331, Percent_Identity=27.4924471299094, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=31.3829787234043, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI32564660, Length=406, Percent_Identity=30.0492610837438, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI25144274, Length=259, Percent_Identity=32.8185328185328, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=415, Percent_Identity=27.2289156626506, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=414, Percent_Identity=24.1545893719807, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=143, Percent_Identity=28.6713286713287, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=386, Percent_Identity=36.0103626943005, Blast_Score=205, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6323470, Length=393, Percent_Identity=30.7888040712468, Blast_Score=179, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6321456, Length=440, Percent_Identity=28.6363636363636, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324386, Length=347, Percent_Identity=27.0893371757925, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=30.1298701298701, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28574759, Length=405, Percent_Identity=30.6172839506173, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI161085790, Length=405, Percent_Identity=30.1234567901235, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21356575, Length=413, Percent_Identity=29.5399515738499, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=25.2358490566038, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=25.2358490566038, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=25.2358490566038, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41052; Mature: 41052

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFDVYPLFNIEIVQGKGCHVWDSEGNEYLDLYGGHAVISVGHSHPTYVKAITEQVNKL
CCCEEECCEEEEEEEECCCCEEECCCCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHH
GFYSNSVINSLQQKLADKLGKASGYDDYSLFLINSGAEANENALKLASFHNGKKRVIAFK
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCEEEEEEE
HAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDASAVEEELKKGDVSSVIIEGIQGV
HHHCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCC
GGIQLPTDDFMRELRNLCTTYDACLILDEIQSGYGRSGKFFAHQYAGIKPDLISVAKGIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCCCHHHHHHHHHHH
NGFPMGGLLISPKFKPVYGMLGTTFGGNHLACAAAIAVLDIMEDERLIDNAAKVGAYLLD
CCCCCCCEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELHKLPGIKEIRGRGLMIGIEFEESIKEVRSKLLFEEKVFTGVAGTHTIRLLPPLCLTMD
HHHHCCCCHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
EAKEFIRRFKKVLNA
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLFDVYPLFNIEIVQGKGCHVWDSEGNEYLDLYGGHAVISVGHSHPTYVKAITEQVNKL
CCCEEECCEEEEEEEECCCCEEECCCCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHH
GFYSNSVINSLQQKLADKLGKASGYDDYSLFLINSGAEANENALKLASFHNGKKRVIAFK
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCEEEEEEE
HAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDASAVEEELKKGDVSSVIIEGIQGV
HHHCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCC
GGIQLPTDDFMRELRNLCTTYDACLILDEIQSGYGRSGKFFAHQYAGIKPDLISVAKGIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCCCHHHHHHHHHHH
NGFPMGGLLISPKFKPVYGMLGTTFGGNHLACAAAIAVLDIMEDERLIDNAAKVGAYLLD
CCCCCCCEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELHKLPGIKEIRGRGLMIGIEFEESIKEVRSKLLFEEKVFTGVAGTHTIRLLPPLCLTMD
HHHHCCCCHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
EAKEFIRRFKKVLNA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025667; 9384377 [H]