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The map label for this gene is trpD

Identifier: 150006570

GI number: 150006570

Start: 5032805

End: 5033800

Strand: Direct

Name: trpD

Synonym: BVU_4090

Alternate gene names: 150006570

Gene position: 5032805-5033800 (Clockwise)

Preceding gene: 150006569

Following gene: 150006571

Centisome position: 97.47

GC content: 47.39

Gene sequence:

>996_bases
ATGAAAGCTATATTATCCCGCCTCTTCAATCACGAGGAACTGACCCGAAAAGAAGCAAAGAATTTGCTGCTCAACATAAC
CCGGGGAATGTATAACGACGCACAGATAGCCGCCCTGCTGACCGTTTTCCAAATGCGCGGCATCAAAGTAGAAGAATTGA
TAGGTTTCCGTGAAGCATTGCTCACCACCCGCATACCTATAGACTTTTCCGCTTACACCCCTATTGACATTGTGGGCACA
GGCGGTGATGGAAAAAATACCTTCAATATCTCTACTTGCGCCTGCTTCATTGTAGCAGGAGCCGGATATCATGTTGCCAA
ACACGGCAACTATGGCGCGACTTCCGTCAGCGGAGCCAGCAATGTCATCGAACAACACGGTGTAAAATTCACGAACAATC
CGGATAAGCTGACCCGTTCTATGGAAGAATGTGGAATGGTCTATATGCATGCCCAGTTGTTCAATCCTGCCATGAAAAGT
GTAGGCCCTGTCCGCAAAGCACTGCAAGTACGTACCATATTCAACCTGCTAGGTCCGCTGGTTAATCCATGTCTTCCGGC
TTACCAACTTCTAGGAGTCGCCGATCTGCCGCAAATGCGCCTTTATACCAACGTGTTCCAAAAACTGGGCATTGGCTTTG
CCGTAGTAAACAACCTGGACGGTTACGACGAAATCTCACTGACCGATGAATTCAAAGTGATGACCAATCGCTACGAAACC
ATCTACAAGCCATCCGAACTAGGCTTCTCTCTCGCCAGACAAGAAGAGCTTTATGGTGGGAACACTCCCGAAGAAGCGTC
GAAAATCTTCAATAACGTACTGGAGAACAAAGCCACCAAAGCCCAGACAGACTGTGTACTGATTAACGCTTCTTTTGCCA
TACAAGCCATGGAACCGGCCAAACCGATAGAAGAATGCGTGGCCATCGCCCGTGAATCATTGGAAAGCGGAAAAGCATTG
AATACATTGAAAAAATTTGTGGAACTGAACAGTTGA

Upstream 100 bases:

>100_bases
CCACGGCATCCAGTTTCATCCCGAATCCGTACTAACCCCCGATGGTAAAGCCATGATAGCCAACTTTCTAAACGCATAAC
CCCAACCGTACATAATAAAT

Downstream 100 bases:

>100_bases
CTACACACCCGGTATTCCACTACCAAACGCCTCATACAATGACAGATATATTAACAGAAATCATCGCCTGCAAGCAAATC
GAGATCGAACTGCAAAAGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKAILSRLFNHEELTRKEAKNLLLNITRGMYNDAQIAALLTVFQMRGIKVEELIGFREALLTTRIPIDFSAYTPIDIVGT
GGDGKNTFNISTCACFIVAGAGYHVAKHGNYGATSVSGASNVIEQHGVKFTNNPDKLTRSMEECGMVYMHAQLFNPAMKS
VGPVRKALQVRTIFNLLGPLVNPCLPAYQLLGVADLPQMRLYTNVFQKLGIGFAVVNNLDGYDEISLTDEFKVMTNRYET
IYKPSELGFSLARQEELYGGNTPEEASKIFNNVLENKATKAQTDCVLINASFAIQAMEPAKPIEECVAIARESLESGKAL
NTLKKFVELNS

Sequences:

>Translated_331_residues
MKAILSRLFNHEELTRKEAKNLLLNITRGMYNDAQIAALLTVFQMRGIKVEELIGFREALLTTRIPIDFSAYTPIDIVGT
GGDGKNTFNISTCACFIVAGAGYHVAKHGNYGATSVSGASNVIEQHGVKFTNNPDKLTRSMEECGMVYMHAQLFNPAMKS
VGPVRKALQVRTIFNLLGPLVNPCLPAYQLLGVADLPQMRLYTNVFQKLGIGFAVVNNLDGYDEISLTDEFKVMTNRYET
IYKPSELGFSLARQEELYGGNTPEEASKIFNNVLENKATKAQTDCVLINASFAIQAMEPAKPIEECVAIARESLESGKAL
NTLKKFVELNS
>Mature_331_residues
MKAILSRLFNHEELTRKEAKNLLLNITRGMYNDAQIAALLTVFQMRGIKVEELIGFREALLTTRIPIDFSAYTPIDIVGT
GGDGKNTFNISTCACFIVAGAGYHVAKHGNYGATSVSGASNVIEQHGVKFTNNPDKLTRSMEECGMVYMHAQLFNPAMKS
VGPVRKALQVRTIFNLLGPLVNPCLPAYQLLGVADLPQMRLYTNVFQKLGIGFAVVNNLDGYDEISLTDEFKVMTNRYET
IYKPSELGFSLARQEELYGGNTPEEASKIFNNVLENKATKAQTDCVLINASFAIQAMEPAKPIEECVAIARESLESGKAL
NTLKKFVELNS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=34.982332155477, Blast_Score=155, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320561, Length=282, Percent_Identity=30.4964539007092, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BACV8 (A6L7M8)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001301314.1
- STRING:   A6L7M8
- GeneID:   5305049
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_4090
- NMPDR:   fig|435590.6.peg.3803
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   GSADIME
- ProtClustDB:   CLSK913502
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36461; Mature: 36461

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILSRLFNHEELTRKEAKNLLLNITRGMYNDAQIAALLTVFQMRGIKVEELIGFREAL
CHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LTTRIPIDFSAYTPIDIVGTGGDGKNTFNISTCACFIVAGAGYHVAKHGNYGATSVSGAS
HHHCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
NVIEQHGVKFTNNPDKLTRSMEECGMVYMHAQLFNPAMKSVGPVRKALQVRTIFNLLGPL
HHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNPCLPAYQLLGVADLPQMRLYTNVFQKLGIGFAVVNNLDGYDEISLTDEFKVMTNRYET
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHH
IYKPSELGFSLARQEELYGGNTPEEASKIFNNVLENKATKAQTDCVLINASFAIQAMEPA
HCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHEEEECCCC
KPIEECVAIARESLESGKALNTLKKFVELNS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAILSRLFNHEELTRKEAKNLLLNITRGMYNDAQIAALLTVFQMRGIKVEELIGFREAL
CHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LTTRIPIDFSAYTPIDIVGTGGDGKNTFNISTCACFIVAGAGYHVAKHGNYGATSVSGAS
HHHCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
NVIEQHGVKFTNNPDKLTRSMEECGMVYMHAQLFNPAMKSVGPVRKALQVRTIFNLLGPL
HHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNPCLPAYQLLGVADLPQMRLYTNVFQKLGIGFAVVNNLDGYDEISLTDEFKVMTNRYET
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHH
IYKPSELGFSLARQEELYGGNTPEEASKIFNNVLENKATKAQTDCVLINASFAIQAMEPA
HCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHEEEECCCC
KPIEECVAIARESLESGKALNTLKKFVELNS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA