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The map label for this gene is infC

Identifier: 150006538

GI number: 150006538

Start: 4992690

End: 4993286

Strand: Reverse

Name: infC

Synonym: BVU_4058

Alternate gene names: 150006538

Gene position: 4993286-4992690 (Counterclockwise)

Preceding gene: 150006539

Following gene: 150006537

Centisome position: 96.71

GC content: 39.87

Gene sequence:

>597_bases
ATGAAGAATGACAGTTTAAAAGGGCAACACAGAATCAATGAACAGATTCGTGCCAAAGAAGTCCGCATTGTGGGCGACGA
TGTAGAATCGGCAGTTTATCCGATAGCTCAAGCTTTAAAAATGGCTGAGGATCATGAGGCTGACCTAGTTGAAATTTCAC
CCAATGCTGTTCCTCCAGTTTGTAGAATTATTGATTATTCTAAATTTCTTTATCAATTAAAGAAACGTCAAAAGGAACAA
AAGGCTAAACAGGTAAAGGTAAACGTAAAGGAAATCCGTTTCGGACCTCAAACAGATGATCATGACTACAACTTCAAGTT
GAAACATGCCATCGGATTCTTGCAGGACGGAGACAAGGTGAAAGCATATGTGTTCTTTAAAGGTCGTTCCATTCTTTTCA
AAGAACAAGGCGAAGTATTGTTGCTTCGTTTTGCGAATGACTTGGAAGAATATGCAAAAGTAGAGCAGATGCCCTTGTTG
GAAGGTAAGAGAATGACTATTTCTTTGGCTCCGAAGAAAGCGGGCTCTCCGAAGAAGGCAGAAACGGATACTGCTAAAAA
GGAAAATCCGAAAAAGGCAGTAGAAACAAAAGAATGA

Upstream 100 bases:

>100_bases
CAAAAGAGCGCATTGTTAAACCTTTATGTATTCTTTTGCGTTAAGATAAAGAAATACTAATTAAAATAAGAAGAAACAAA
CAGGAACTAAAAGTTTTTTA

Downstream 100 bases:

>100_bases
AAAAAGAGTGCGTAACGCGCCGGTATAGTGCGTTACCACCATTTGAATAATAATTTAAAATTAAAAACAAGATGCCAAAG
ATCAAGACTAACTCCGGTTC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKNDSLKGQHRINEQIRAKEVRIVGDDVESAVYPIAQALKMAEDHEADLVEISPNAVPPVCRIIDYSKFLYQLKKRQKEQ
KAKQVKVNVKEIRFGPQTDDHDYNFKLKHAIGFLQDGDKVKAYVFFKGRSILFKEQGEVLLLRFANDLEEYAKVEQMPLL
EGKRMTISLAPKKAGSPKKAETDTAKKENPKKAVETKE

Sequences:

>Translated_198_residues
MKNDSLKGQHRINEQIRAKEVRIVGDDVESAVYPIAQALKMAEDHEADLVEISPNAVPPVCRIIDYSKFLYQLKKRQKEQ
KAKQVKVNVKEIRFGPQTDDHDYNFKLKHAIGFLQDGDKVKAYVFFKGRSILFKEQGEVLLLRFANDLEEYAKVEQMPLL
EGKRMTISLAPKKAGSPKKAETDTAKKENPKKAVETKE
>Mature_198_residues
MKNDSLKGQHRINEQIRAKEVRIVGDDVESAVYPIAQALKMAEDHEADLVEISPNAVPPVCRIIDYSKFLYQLKKRQKEQ
KAKQVKVNVKEIRFGPQTDDHDYNFKLKHAIGFLQDGDKVKAYVFFKGRSILFKEQGEVLLLRFANDLEEYAKVEQMPLL
EGKRMTISLAPKKAGSPKKAETDTAKKENPKKAVETKE

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=50, Blast_Score=141, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_BACV8 (A6L7J6)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001301282.1
- ProteinModelPortal:   A6L7J6
- STRING:   A6L7J6
- GeneID:   5305017
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_4058
- NMPDR:   fig|435590.6.peg.3772
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 22642; Mature: 22642

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDSLKGQHRINEQIRAKEVRIVGDDVESAVYPIAQALKMAEDHEADLVEISPNAVPPV
CCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHH
CRIIDYSKFLYQLKKRQKEQKAKQVKVNVKEIRFGPQTDDHDYNFKLKHAIGFLQDGDKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCEEHHHHHCCCCCCCEE
KAYVFFKGRSILFKEQGEVLLLRFANDLEEYAKVEQMPLLEGKRMTISLAPKKAGSPKKA
EEEEEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
ETDTAKKENPKKAVETKE
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNDSLKGQHRINEQIRAKEVRIVGDDVESAVYPIAQALKMAEDHEADLVEISPNAVPPV
CCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHH
CRIIDYSKFLYQLKKRQKEQKAKQVKVNVKEIRFGPQTDDHDYNFKLKHAIGFLQDGDKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCEEHHHHHCCCCCCCEE
KAYVFFKGRSILFKEQGEVLLLRFANDLEEYAKVEQMPLLEGKRMTISLAPKKAGSPKKA
EEEEEEECCEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
ETDTAKKENPKKAVETKE
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA