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The map label for this gene is luxQ [H]

Identifier: 150006465

GI number: 150006465

Start: 4902356

End: 4904206

Strand: Direct

Name: luxQ [H]

Synonym: BVU_3984

Alternate gene names: 150006465

Gene position: 4902356-4904206 (Clockwise)

Preceding gene: 150006463

Following gene: 150006466

Centisome position: 94.95

GC content: 41.0

Gene sequence:

>1851_bases
ATGAAAATTCCGAGTAATATATTGCACGATAAGCAGTATGCAGACAAAATTCTGGAAATTACGGCTGATACTATGTTTTT
CGTATATAAAGACGGCACCTGTTTAGACTTCAAGGCTAATACGACGGACTTCTTTATAAAAGAACAAGATATTATAGGGA
GAAATATATTCTCTTATTTCCCCGTAGAAACGGCACGGGAGATGTATGCGGAATTCATCAAAGTACGGGCAGGAGACAAA
CCTTCCGCACGGAATTACAAATTAATATTGGAAGATGACGTGAAATACTACAAATGTATTATCAGCAAGTATGATGAGGA
GCATTTTCTTTTTCAATACAGGGATATCACAGGCCGGAGTGTCGTCAGGCTGAAACTGGAAAAAAAGCAAAAAGATTTGT
GCGAAGTAGAAAAAGCCGCAAGAATAGGATTATGGGCATACGATTCGTCCACACGGCTCTTCACTTACTCGGGATACACC
CGGATATTCTGTAACGATGAGGAACAGAAACAGATTTCCATAGATGAATACATGAACTATATGCACCTTGATGACAAGGA
CCGTTTCAGTCAATGGCTGGAAGAAAACCTGAAGGAGAAAGATGCTTCCAATACCGTAAACTATAGACTCCTTATTGACG
GAAAGACCGTCAATATGAGAATAAAAACATACCACAAAGAGGTATATATGCAAAGGACCGTATTGGAAGGATATATACAG
AACACATCCGAAATTGTTTGGAAAGCAGAACGCTCCAACCAGCTGAAATCTGCCTTCCTTGCCAATATGAGCCATGAAAT
CCGTACGCCGTTGAATGCCATTCTGGGATTCTCACGCATTATAGCCGAAACGGAAAACGCCGAGGAAAGATTGCAGTATT
ACGATATTGTAGAAAAAAACAACATGCGCTTGCAGGAACTTATCAACGAGATTTTGGACCTGTCGAAGATTGAATCGGGC
ATGATGGAGTTCAACTATGCGCCTGTATCCCTTTATATTTTATGTGAGGATGTAAAAAACACGTATAGTTTCCGGTGTCA
ACCCGGAGTGGAGCTTGTTTTCGAAGAGTCCGATCCGTCACTGGTTATCTCGACAGACAGGAACCGCTTGTTTCAGGTTT
TCTCCAATCTGATAGGTAATGCTACGAAATTCACCGCCAAAGGTTCTATCAGCTTCGGGTATAAATTGAAGGAAAAAGAG
ATTGTTTTTCATGTAGCCGATACCGGAAGCGGTATTTCCGATGACAAGATAGACAAGATATTCGATCGTTTCATCATGGC
CAACAACCAAGTGCAAGGCACAGGACTGGGGCTTTCCATCAGCAAAATCATTGTAGAAAAGTTAGGAGGAAAAATAGCTG
TACAATCCAAAATGGGAACCGGGACCACATTCACTTTTACATTGCCTTACATTTCGGCAAACGGAGATATGAAATGGGAG
GAAAAACTTACACCGGCTTCCATTAAAGACAACAATAGAACTTCCCATCAGGAGATGACCATCCTAGTGGCGGAAGACTA
TCAAAGCAATTATGACTTGATAGAGGCTATGCTCGGAAAAATGTACAAACTGGTGCATGCTCATGACGGAATGGAGGCTA
TCATATTCTATGAACAATACAAACCCGACTTAATTTTGATGGATATAAAAATGCCTAACATCAATGGTCTGGACGCCACC
AAAGCCATCCGGGAAATGTCTGCCAGCGTACCTGTCATCGCTGTAAGCGCATACGCATATGAAAAAGACAAAATAGCTGC
CATAGAAAGCGGATGCAATGAGTTTTTAACCAAACCGGTATCTGCCGACTTATTGAAAATGACTATAAACAAGTATCTAA
AACAAAAGTAA

Upstream 100 bases:

>100_bases
GATATAAACAATATTTTTTTTGTATATTTGCTGTCAGTAACAAATATCACGCATCTAAATTCGCTAAGAGAAACAGTATA
TTGAGAATCATACTATTAAT

Downstream 100 bases:

>100_bases
TTTATGGGAAGATTAGCCGTATACAAATTTGCCTATTTTTTATCTATCCTGTTCACAATCTTCATTCTGGGACTTTCCAT
CTTCGCTTACTTCTCAGGTA

Product: two-component hybrid sensor kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MKIPSNILHDKQYADKILEITADTMFFVYKDGTCLDFKANTTDFFIKEQDIIGRNIFSYFPVETAREMYAEFIKVRAGDK
PSARNYKLILEDDVKYYKCIISKYDEEHFLFQYRDITGRSVVRLKLEKKQKDLCEVEKAARIGLWAYDSSTRLFTYSGYT
RIFCNDEEQKQISIDEYMNYMHLDDKDRFSQWLEENLKEKDASNTVNYRLLIDGKTVNMRIKTYHKEVYMQRTVLEGYIQ
NTSEIVWKAERSNQLKSAFLANMSHEIRTPLNAILGFSRIIAETENAEERLQYYDIVEKNNMRLQELINEILDLSKIESG
MMEFNYAPVSLYILCEDVKNTYSFRCQPGVELVFEESDPSLVISTDRNRLFQVFSNLIGNATKFTAKGSISFGYKLKEKE
IVFHVADTGSGISDDKIDKIFDRFIMANNQVQGTGLGLSISKIIVEKLGGKIAVQSKMGTGTTFTFTLPYISANGDMKWE
EKLTPASIKDNNRTSHQEMTILVAEDYQSNYDLIEAMLGKMYKLVHAHDGMEAIIFYEQYKPDLILMDIKMPNINGLDAT
KAIREMSASVPVIAVSAYAYEKDKIAAIESGCNEFLTKPVSADLLKMTINKYLKQK

Sequences:

>Translated_616_residues
MKIPSNILHDKQYADKILEITADTMFFVYKDGTCLDFKANTTDFFIKEQDIIGRNIFSYFPVETAREMYAEFIKVRAGDK
PSARNYKLILEDDVKYYKCIISKYDEEHFLFQYRDITGRSVVRLKLEKKQKDLCEVEKAARIGLWAYDSSTRLFTYSGYT
RIFCNDEEQKQISIDEYMNYMHLDDKDRFSQWLEENLKEKDASNTVNYRLLIDGKTVNMRIKTYHKEVYMQRTVLEGYIQ
NTSEIVWKAERSNQLKSAFLANMSHEIRTPLNAILGFSRIIAETENAEERLQYYDIVEKNNMRLQELINEILDLSKIESG
MMEFNYAPVSLYILCEDVKNTYSFRCQPGVELVFEESDPSLVISTDRNRLFQVFSNLIGNATKFTAKGSISFGYKLKEKE
IVFHVADTGSGISDDKIDKIFDRFIMANNQVQGTGLGLSISKIIVEKLGGKIAVQSKMGTGTTFTFTLPYISANGDMKWE
EKLTPASIKDNNRTSHQEMTILVAEDYQSNYDLIEAMLGKMYKLVHAHDGMEAIIFYEQYKPDLILMDIKMPNINGLDAT
KAIREMSASVPVIAVSAYAYEKDKIAAIESGCNEFLTKPVSADLLKMTINKYLKQK
>Mature_616_residues
MKIPSNILHDKQYADKILEITADTMFFVYKDGTCLDFKANTTDFFIKEQDIIGRNIFSYFPVETAREMYAEFIKVRAGDK
PSARNYKLILEDDVKYYKCIISKYDEEHFLFQYRDITGRSVVRLKLEKKQKDLCEVEKAARIGLWAYDSSTRLFTYSGYT
RIFCNDEEQKQISIDEYMNYMHLDDKDRFSQWLEENLKEKDASNTVNYRLLIDGKTVNMRIKTYHKEVYMQRTVLEGYIQ
NTSEIVWKAERSNQLKSAFLANMSHEIRTPLNAILGFSRIIAETENAEERLQYYDIVEKNNMRLQELINEILDLSKIESG
MMEFNYAPVSLYILCEDVKNTYSFRCQPGVELVFEESDPSLVISTDRNRLFQVFSNLIGNATKFTAKGSISFGYKLKEKE
IVFHVADTGSGISDDKIDKIFDRFIMANNQVQGTGLGLSISKIIVEKLGGKIAVQSKMGTGTTFTFTLPYISANGDMKWE
EKLTPASIKDNNRTSHQEMTILVAEDYQSNYDLIEAMLGKMYKLVHAHDGMEAIIFYEQYKPDLILMDIKMPNINGLDAT
KAIREMSASVPVIAVSAYAYEKDKIAAIESGCNEFLTKPVSADLLKMTINKYLKQK

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=377, Percent_Identity=30.5039787798408, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1788713, Length=379, Percent_Identity=30.6068601583113, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081816, Length=373, Percent_Identity=26.5415549597855, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789149, Length=277, Percent_Identity=33.5740072202166, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=313, Percent_Identity=29.073482428115, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1786600, Length=378, Percent_Identity=26.7195767195767, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=30.5785123966942, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=32.5688073394495, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=29.1845493562232, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=30.1724137931034, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=210, Percent_Identity=25.2380952380952, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=25.5060728744939, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=25.4807692307692, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786911, Length=116, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788550, Length=88, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=171, Percent_Identity=30.9941520467836, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322044, Length=152, Percent_Identity=29.6052631578947, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71052; Mature: 71052

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPSNILHDKQYADKILEITADTMFFVYKDGTCLDFKANTTDFFIKEQDIIGRNIFSYF
CCCCCHHHCCHHHHHHHHHEEECEEEEEEECCEEEEEECCCCEEEEECCHHHCCHHHHHC
PVETAREMYAEFIKVRAGDKPSARNYKLILEDDVKYYKCIISKYDEEHFLFQYRDITGRS
CHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCCE
VVRLKLEKKQKDLCEVEKAARIGLWAYDSSTRLFTYSGYTRIFCNDEEQKQISIDEYMNY
EEEEEEHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCEEEEEECCCCHHEEEHHHHHHH
MHLDDKDRFSQWLEENLKEKDASNTVNYRLLIDGKTVNMRIKTYHKEVYMQRTVLEGYIQ
HCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHC
NTSEIVWKAERSNQLKSAFLANMSHEIRTPLNAILGFSRIIAETENAEERLQYYDIVEKN
CCHHEEEECHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
NMRLQELINEILDLSKIESGMMEFNYAPVSLYILCEDVKNTYSFRCQPGVELVFEESDPS
CCHHHHHHHHHHHHHHHHCCHHEECCCCEEEEEEEECCCCCEEEEECCCCEEEEECCCCC
LVISTDRNRLFQVFSNLIGNATKFTAKGSISFGYKLKEKEIVFHVADTGSGISDDKIDKI
EEEECCHHHHHHHHHHHHCCCEEEEECCCEEECEEEECCEEEEEEECCCCCCCHHHHHHH
FDRFIMANNQVQGTGLGLSISKIIVEKLGGKIAVQSKMGTGTTFTFTLPYISANGDMKWE
HHHHHHCCCEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEEECCCCCCHH
EKLTPASIKDNNRTSHQEMTILVAEDYQSNYDLIEAMLGKMYKLVHAHDGMEAIIFYEQY
HCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
KPDLILMDIKMPNINGLDATKAIREMSASVPVIAVSAYAYEKDKIAAIESGCNEFLTKPV
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHCHHHHHCCCC
SADLLKMTINKYLKQK
CHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIPSNILHDKQYADKILEITADTMFFVYKDGTCLDFKANTTDFFIKEQDIIGRNIFSYF
CCCCCHHHCCHHHHHHHHHEEECEEEEEEECCEEEEEECCCCEEEEECCHHHCCHHHHHC
PVETAREMYAEFIKVRAGDKPSARNYKLILEDDVKYYKCIISKYDEEHFLFQYRDITGRS
CHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEEECCCCCE
VVRLKLEKKQKDLCEVEKAARIGLWAYDSSTRLFTYSGYTRIFCNDEEQKQISIDEYMNY
EEEEEEHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCEEEEEECCCCHHEEEHHHHHHH
MHLDDKDRFSQWLEENLKEKDASNTVNYRLLIDGKTVNMRIKTYHKEVYMQRTVLEGYIQ
HCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHC
NTSEIVWKAERSNQLKSAFLANMSHEIRTPLNAILGFSRIIAETENAEERLQYYDIVEKN
CCHHEEEECHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
NMRLQELINEILDLSKIESGMMEFNYAPVSLYILCEDVKNTYSFRCQPGVELVFEESDPS
CCHHHHHHHHHHHHHHHHCCHHEECCCCEEEEEEEECCCCCEEEEECCCCEEEEECCCCC
LVISTDRNRLFQVFSNLIGNATKFTAKGSISFGYKLKEKEIVFHVADTGSGISDDKIDKI
EEEECCHHHHHHHHHHHHCCCEEEEECCCEEECEEEECCEEEEEEECCCCCCCHHHHHHH
FDRFIMANNQVQGTGLGLSISKIIVEKLGGKIAVQSKMGTGTTFTFTLPYISANGDMKWE
HHHHHHCCCEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEEECCCCCCHH
EKLTPASIKDNNRTSHQEMTILVAEDYQSNYDLIEAMLGKMYKLVHAHDGMEAIIFYEQY
HCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
KPDLILMDIKMPNINGLDATKAIREMSASVPVIAVSAYAYEKDKIAAIESGCNEFLTKPV
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHCHHHHHCCCC
SADLLKMTINKYLKQK
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]