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The map label for this gene is yycG [H]

Identifier: 150006384

GI number: 150006384

Start: 4813005

End: 4813646

Strand: Direct

Name: yycG [H]

Synonym: BVU_3903

Alternate gene names: 150006384

Gene position: 4813005-4813646 (Clockwise)

Preceding gene: 150006383

Following gene: 150006393

Centisome position: 93.22

GC content: 46.42

Gene sequence:

>642_bases
ATGAGCCATGAAATCCGTACTCCGCTTAATGCCATCGTGGGATTCTCCAACCTGCTCACTACCGAGAAAAACATCTCGGA
AGAAGAGAAAAAAGAGTTTGCCTCCATCATAGACAACAATACCAGACTCTTGTTGAAGCTGGTCAATGATGTGCTGGAAC
TATCCCGTATAGAATCCGGCAATATGTCCTTTCATTGCGAGGATTGCAGCGCGCATCATTTCGCCGAAACGGTCTATCAG
ACCCATCAGGTAATTATTCTCCCTCCAGTGGAATTCATCAAAGAATTTCCCGACGAGGATGTGACCATACACATAGACCG
TATGCGCCTCACCCAAGTCATCACCAACTTTTTGGGAAACGCCAAGAAGTTCACCTCCCAAGGACACATCAAACTGGGTT
ATTTCTGCGACAAAGAGAAAAAGGAAATCCATATCTTCGTAGAAGATACCGGTGCGGGAATCCCTAAAGAAGAATTACAA
ATGATATTCGAGCGGTTCTACAAGCGGAATGAGTTTGTACAGGGTGTAGGGCTGGGACTCGCCATCAGCAAGGTCATTGT
AGAAAAAATGAACGGACACATCGATGTGCAATCCGAGGTGAACAAGGGCAGCCGTTTCACCGCCGTACTGCCCTATCTGT
AA

Upstream 100 bases:

>100_bases
TCTGGTAAACATTCAGGAGATCAAAGACAAGGAAGAAGAACTGATACGCGCCCGCAAACTGGCGGAACAGGCGGAACTGA
AACAATCCTTCCTGGCCAAC

Downstream 100 bases:

>100_bases
TTTTATTCCTGTGCAGGCTGTTTAGGCAGGGCGAACTGCAAGACCAGATACGCCAGCACACCCGCCAGCACCGTTCCCAG
TATGACACCCATCTTTGCCT

Product: putative two-component regulator sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSHEIRTPLNAIVGFSNLLTTEKNISEEEKKEFASIIDNNTRLLLKLVNDVLELSRIESGNMSFHCEDCSAHHFAETVYQ
THQVIILPPVEFIKEFPDEDVTIHIDRMRLTQVITNFLGNAKKFTSQGHIKLGYFCDKEKKEIHIFVEDTGAGIPKEELQ
MIFERFYKRNEFVQGVGLGLAISKVIVEKMNGHIDVQSEVNKGSRFTAVLPYL

Sequences:

>Translated_213_residues
MSHEIRTPLNAIVGFSNLLTTEKNISEEEKKEFASIIDNNTRLLLKLVNDVLELSRIESGNMSFHCEDCSAHHFAETVYQ
THQVIILPPVEFIKEFPDEDVTIHIDRMRLTQVITNFLGNAKKFTSQGHIKLGYFCDKEKKEIHIFVEDTGAGIPKEELQ
MIFERFYKRNEFVQGVGLGLAISKVIVEKMNGHIDVQSEVNKGSRFTAVLPYL
>Mature_212_residues
SHEIRTPLNAIVGFSNLLTTEKNISEEEKKEFASIIDNNTRLLLKLVNDVLELSRIESGNMSFHCEDCSAHHFAETVYQT
HQVIILPPVEFIKEFPDEDVTIHIDRMRLTQVITNFLGNAKKFTSQGHIKLGYFCDKEKKEIHIFVEDTGAGIPKEELQM
IFERFYKRNEFVQGVGLGLAISKVIVEKMNGHIDVQSEVNKGSRFTAVLPYL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=35.4838709677419, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789149, Length=218, Percent_Identity=31.1926605504587, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788713, Length=220, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI48994928, Length=217, Percent_Identity=32.7188940092166, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI87081816, Length=215, Percent_Identity=33.953488372093, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=29.4930875576037, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1788549, Length=213, Percent_Identity=29.5774647887324, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=29.7674418604651, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.7037037037037, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=222, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 24354; Mature: 24223

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHEIRTPLNAIVGFSNLLTTEKNISEEEKKEFASIIDNNTRLLLKLVNDVLELSRIESG
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
NMSFHCEDCSAHHFAETVYQTHQVIILPPVEFIKEFPDEDVTIHIDRMRLTQVITNFLGN
CCEEEECCCCHHHHHHHHHHCCCEEEECCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCC
AKKFTSQGHIKLGYFCDKEKKEIHIFVEDTGAGIPKEELQMIFERFYKRNEFVQGVGLGL
HHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AISKVIVEKMNGHIDVQSEVNKGSRFTAVLPYL
HHHHHHHHHHCCCEEEHHHCCCCCEEEEECCCC
>Mature Secondary Structure 
SHEIRTPLNAIVGFSNLLTTEKNISEEEKKEFASIIDNNTRLLLKLVNDVLELSRIESG
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
NMSFHCEDCSAHHFAETVYQTHQVIILPPVEFIKEFPDEDVTIHIDRMRLTQVITNFLGN
CCEEEECCCCHHHHHHHHHHCCCEEEECCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCC
AKKFTSQGHIKLGYFCDKEKKEIHIFVEDTGAGIPKEELQMIFERFYKRNEFVQGVGLGL
HHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AISKVIVEKMNGHIDVQSEVNKGSRFTAVLPYL
HHHHHHHHHHCCCEEEHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]