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The map label for this gene is pyrD [H]

Identifier: 150006350

GI number: 150006350

Start: 4769573

End: 4770547

Strand: Direct

Name: pyrD [H]

Synonym: BVU_3869

Alternate gene names: 150006350

Gene position: 4769573-4770547 (Clockwise)

Preceding gene: 150006349

Following gene: 150006351

Centisome position: 92.38

GC content: 46.87

Gene sequence:

>975_bases
ATGACTCAATTAAAAACCACTTTTGCCGGGTTGTCACTGCGCAATCCTATAATCATCAGCAGTTCCAGCCTTACAAACAG
CGCTGAAAAGAACAAGAAACTGGAGCTGGCAGGCGCCGGAGCCATTGTTTTGAAATCAGTTTTCGAAGAGCAGATCATGA
TGGAAGCACATCACATGGCTACTTATGGCTCTCCCGAAGGAGATGACTACTTGAGCACATATGTACGCTCTCATGCATTG
AACGAATATATTTCATTGATTGAACAGACTAAAAAGCTTTGCACCATTCCTGTCATTGCCAGCATCAACTGCTTCAGCAA
CTCAGAATGGACAGACTTTGCCCGTACCGTGGAAGCAGCAGAAGCCGACGCACTGGAAATCAACATCCTTTCCTTGCAGA
CCGAAAAAGAATATCAATACGGTTCTTTCGAACAGCGTCATATCGATATCGTAAGCAGTATCAAGAAACAGATTTCCATC
CCCGTCATTGTGAAACTGGGCAGCAATCTGACCAACCCCATCGCACTGATCAACCAGCTTTATGCCAACGGAGCCAATGC
TGTGGTATTGTTCAACCGATTCTACCAGCCGGATATCAATATCGACACCATGACATATTCTGCAGGCGATGTATTCAGTA
CTCCTGCCGACTTGTCCAACGGACTGCGCTGGACTGCTATCGCTTCGGCACAAGTTCCTCAGACAGACTATGCCATCTCG
GGCGGTGTGCACGATGGAAAAGCGATAGTCAAAGCAATTCTGGCAGGCGCTTCGGCTGTAGAACTGTGCAGTGTCATCTA
CCAAAGAGGCAATCAGGCCATTGCAGATATGACAAATGAAATGACCCAATGGATGAACCGGCAAGGCTACAAGGACATCA
GCGAATTCAAGAGCTCGATGAACGCACTGTCTACCGGAGCCAGCAATCCGTTTGAACGTACACAGTTCATGAAGTATTTC
AGCAGCAAAGAATAA

Upstream 100 bases:

>100_bases
ATGTCACACGATTATCCGCTGGCAGTGGAAGCCGGAAGTACACTAGTCAGGGTAGGAAGCAAAATCTTTGGAGAACGAAA
CTATTAAAACTACTATTTAT

Downstream 100 bases:

>100_bases
AAATCAGTGGTTAGTGATTAGTGGTTCATATCCATGCGACATCACAGCGCAGCTCATTAACCACTAACCACTAATCACTA
TTTTTCCTTCTGTTTAATTT

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTQLKTTFAGLSLRNPIIISSSSLTNSAEKNKKLELAGAGAIVLKSVFEEQIMMEAHHMATYGSPEGDDYLSTYVRSHAL
NEYISLIEQTKKLCTIPVIASINCFSNSEWTDFARTVEAAEADALEINILSLQTEKEYQYGSFEQRHIDIVSSIKKQISI
PVIVKLGSNLTNPIALINQLYANGANAVVLFNRFYQPDINIDTMTYSAGDVFSTPADLSNGLRWTAIASAQVPQTDYAIS
GGVHDGKAIVKAILAGASAVELCSVIYQRGNQAIADMTNEMTQWMNRQGYKDISEFKSSMNALSTGASNPFERTQFMKYF
SSKE

Sequences:

>Translated_324_residues
MTQLKTTFAGLSLRNPIIISSSSLTNSAEKNKKLELAGAGAIVLKSVFEEQIMMEAHHMATYGSPEGDDYLSTYVRSHAL
NEYISLIEQTKKLCTIPVIASINCFSNSEWTDFARTVEAAEADALEINILSLQTEKEYQYGSFEQRHIDIVSSIKKQISI
PVIVKLGSNLTNPIALINQLYANGANAVVLFNRFYQPDINIDTMTYSAGDVFSTPADLSNGLRWTAIASAQVPQTDYAIS
GGVHDGKAIVKAILAGASAVELCSVIYQRGNQAIADMTNEMTQWMNRQGYKDISEFKSSMNALSTGASNPFERTQFMKYF
SSKE
>Mature_323_residues
TQLKTTFAGLSLRNPIIISSSSLTNSAEKNKKLELAGAGAIVLKSVFEEQIMMEAHHMATYGSPEGDDYLSTYVRSHALN
EYISLIEQTKKLCTIPVIASINCFSNSEWTDFARTVEAAEADALEINILSLQTEKEYQYGSFEQRHIDIVSSIKKQISIP
VIVKLGSNLTNPIALINQLYANGANAVVLFNRFYQPDINIDTMTYSAGDVFSTPADLSNGLRWTAIASAQVPQTDYAISG
GVHDGKAIVKAILAGASAVELCSVIYQRGNQAIADMTNEMTQWMNRQGYKDISEFKSSMNALSTGASNPFERTQFMKYFS
SKE

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082059, Length=322, Percent_Identity=22.0496894409938, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 35624; Mature: 35492

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLKTTFAGLSLRNPIIISSSSLTNSAEKNKKLELAGAGAIVLKSVFEEQIMMEAHHMA
CCCCHHHHHCCCCCCCEEEECCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
TYGSPEGDDYLSTYVRSHALNEYISLIEQTKKLCTIPVIASINCFSNSEWTDFARTVEAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHEEEEECCCCCCHHHHHHHHHHH
EADALEINILSLQTEKEYQYGSFEQRHIDIVSSIKKQISIPVIVKLGSNLTNPIALINQL
CCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
YANGANAVVLFNRFYQPDINIDTMTYSAGDVFSTPADLSNGLRWTAIASAQVPQTDYAIS
HHCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHCCEEEEEEECCCCCCCCCEEC
GGVHDGKAIVKAILAGASAVELCSVIYQRGNQAIADMTNEMTQWMNRQGYKDISEFKSSM
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NALSTGASNPFERTQFMKYFSSKE
HHHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQLKTTFAGLSLRNPIIISSSSLTNSAEKNKKLELAGAGAIVLKSVFEEQIMMEAHHMA
CCCHHHHHCCCCCCCEEEECCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
TYGSPEGDDYLSTYVRSHALNEYISLIEQTKKLCTIPVIASINCFSNSEWTDFARTVEAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHEEEEECCCCCCHHHHHHHHHHH
EADALEINILSLQTEKEYQYGSFEQRHIDIVSSIKKQISIPVIVKLGSNLTNPIALINQL
CCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
YANGANAVVLFNRFYQPDINIDTMTYSAGDVFSTPADLSNGLRWTAIASAQVPQTDYAIS
HHCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHCCEEEEEEECCCCCCCCCEEC
GGVHDGKAIVKAILAGASAVELCSVIYQRGNQAIADMTNEMTQWMNRQGYKDISEFKSSM
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NALSTGASNPFERTQFMKYFSSKE
HHHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]