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The map label for this gene is lysA [H]

Identifier: 150006338

GI number: 150006338

Start: 4757522

End: 4758682

Strand: Direct

Name: lysA [H]

Synonym: BVU_3857

Alternate gene names: 150006338

Gene position: 4757522-4758682 (Clockwise)

Preceding gene: 150006337

Following gene: 150006341

Centisome position: 92.14

GC content: 45.65

Gene sequence:

>1161_bases
ATGAAAGGAACATTCCCCGTAAACAAGTTCAGAGAGTTGGAAACTCCCTTCTACTATTACGATGTCAATGTGCTGCGAGA
AACCTTGTCATGCATCAACAAAGAAGCAGGCAAATACAATAATTTCTGCGTGCATTACGCCGTGAAGGCCAATGCTAACC
ACAAAGTCCTGACAATTATCCGCGAAAGCGGTCTGGGAGCCGACTGTGTAAGTGGCGGAGAAATCCGCGCAGCCATTAAG
GCCGGATTCCCGACAAACAAAATAGTCTATGCTGGTGTAGGCAAGACAGACTGGGAAATTAATCTGGGTCTGGATTATGA
TATTTTCTGCTTCAACGTAGAGTCCGTACCCGAACTGGAAATCATTAACGAACTGGCTGCCGCCAAAGGCAAAACAGCCC
GTGTAGCTTTCCGTATCAATCCGAATGTAGGTGCGCATACCCATGCAAATATCACCACCGGACTAGCAGAAAACAAATTC
GGTATCAGCATGGAAGATATGGACAAAGTGATTGATATGGCCGGAACATTGCCTCATGTAAAATTTGTAGGCTTACATTT
CCACATCGGTTCTCAGATTCTGGATATGGGTGATTTTGTAGCCTTGTGCAACCGTGTAAACGAACTACAGGAAAAACTCT
ATGCCCGCCAAATCATAGTAGAACATATCAATGTAGGCGGCGGCTTAGGAATTGATTATGCACACCCCAACCGTCAAGCC
ATCCCCAACTTCACGGAATACTTTGCCACTTATCACAAGCATCTGAAACTGCGCCCCCAGCAGACTTTACATTTCGAACT
GGGACGTGCCGTAGTAGGACAGTGCGGCAGCCTTATCAGCAAAGTGATTTATGTAAAGCAAGGAACCAACAAACAGTTTG
CCATATTAGATGCCGGCATGACCGACTTGATTCGTCCTGCCCTTTATCAGGCATACCACAAAATAGAAAATATCACTTCG
GAAGAACCTATGGAAACTTACGATGTGGTAGGCCCCATCTGCGAATCATCCGATGTATTCGGCAAGGCTATTGATTTGAA
CAAAGCACACCGTGGCGACCTTTTCGCTCTCCGTTCAGCAGGAGCATATGGTGAAATTATGGCATCGGCTTACAATTGTC
GTGCATTGCCCAAAGGATATACCTCAGAAGAGTTAGTATAA

Upstream 100 bases:

>100_bases
TGTAGGGGCGGATTGAATCCGCCCGAATACATCCCACTCTACAAAGTTGGTGTTTTCGGGCGAATTTAATTCGCCCTTGC
TCATAAAAACAAAATACAAT

Downstream 100 bases:

>100_bases
ACCAACTCCAACTGCCTGAATAAATAAGAAACAGCGCCGCTTTGATGCAAAGCGGCGCTGTTTCTTATTTAGGGATATTC
AGTAAATGTCTCTAAAAAAT

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKGTFPVNKFRELETPFYYYDVNVLRETLSCINKEAGKYNNFCVHYAVKANANHKVLTIIRESGLGADCVSGGEIRAAIK
AGFPTNKIVYAGVGKTDWEINLGLDYDIFCFNVESVPELEIINELAAAKGKTARVAFRINPNVGAHTHANITTGLAENKF
GISMEDMDKVIDMAGTLPHVKFVGLHFHIGSQILDMGDFVALCNRVNELQEKLYARQIIVEHINVGGGLGIDYAHPNRQA
IPNFTEYFATYHKHLKLRPQQTLHFELGRAVVGQCGSLISKVIYVKQGTNKQFAILDAGMTDLIRPALYQAYHKIENITS
EEPMETYDVVGPICESSDVFGKAIDLNKAHRGDLFALRSAGAYGEIMASAYNCRALPKGYTSEELV

Sequences:

>Translated_386_residues
MKGTFPVNKFRELETPFYYYDVNVLRETLSCINKEAGKYNNFCVHYAVKANANHKVLTIIRESGLGADCVSGGEIRAAIK
AGFPTNKIVYAGVGKTDWEINLGLDYDIFCFNVESVPELEIINELAAAKGKTARVAFRINPNVGAHTHANITTGLAENKF
GISMEDMDKVIDMAGTLPHVKFVGLHFHIGSQILDMGDFVALCNRVNELQEKLYARQIIVEHINVGGGLGIDYAHPNRQA
IPNFTEYFATYHKHLKLRPQQTLHFELGRAVVGQCGSLISKVIYVKQGTNKQFAILDAGMTDLIRPALYQAYHKIENITS
EEPMETYDVVGPICESSDVFGKAIDLNKAHRGDLFALRSAGAYGEIMASAYNCRALPKGYTSEELV
>Mature_386_residues
MKGTFPVNKFRELETPFYYYDVNVLRETLSCINKEAGKYNNFCVHYAVKANANHKVLTIIRESGLGADCVSGGEIRAAIK
AGFPTNKIVYAGVGKTDWEINLGLDYDIFCFNVESVPELEIINELAAAKGKTARVAFRINPNVGAHTHANITTGLAENKF
GISMEDMDKVIDMAGTLPHVKFVGLHFHIGSQILDMGDFVALCNRVNELQEKLYARQIIVEHINVGGGLGIDYAHPNRQA
IPNFTEYFATYHKHLKLRPQQTLHFELGRAVVGQCGSLISKVIYVKQGTNKQFAILDAGMTDLIRPALYQAYHKIENITS
EEPMETYDVVGPICESSDVFGKAIDLNKAHRGDLFALRSAGAYGEIMASAYNCRALPKGYTSEELV

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=396, Percent_Identity=30.8080808080808, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 42747; Mature: 42747

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTFPVNKFRELETPFYYYDVNVLRETLSCINKEAGKYNNFCVHYAVKANANHKVLTII
CCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEE
RESGLGADCVSGGEIRAAIKAGFPTNKIVYAGVGKTDWEINLGLDYDIFCFNVESVPELE
ECCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCHHH
IINELAAAKGKTARVAFRINPNVGAHTHANITTGLAENKFGISMEDMDKVIDMAGTLPHV
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCE
KFVGLHFHIGSQILDMGDFVALCNRVNELQEKLYARQIIVEHINVGGGLGIDYAHPNRQA
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IPNFTEYFATYHKHLKLRPQQTLHFELGRAVVGQCGSLISKVIYVKQGTNKQFAILDAGM
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECCH
TDLIRPALYQAYHKIENITSEEPMETYDVVGPICESSDVFGKAIDLNKAHRGDLFALRSA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEEECC
GAYGEIMASAYNCRALPKGYTSEELV
CCHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGTFPVNKFRELETPFYYYDVNVLRETLSCINKEAGKYNNFCVHYAVKANANHKVLTII
CCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEE
RESGLGADCVSGGEIRAAIKAGFPTNKIVYAGVGKTDWEINLGLDYDIFCFNVESVPELE
ECCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCHHH
IINELAAAKGKTARVAFRINPNVGAHTHANITTGLAENKFGISMEDMDKVIDMAGTLPHV
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCE
KFVGLHFHIGSQILDMGDFVALCNRVNELQEKLYARQIIVEHINVGGGLGIDYAHPNRQA
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IPNFTEYFATYHKHLKLRPQQTLHFELGRAVVGQCGSLISKVIYVKQGTNKQFAILDAGM
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECCH
TDLIRPALYQAYHKIENITSEEPMETYDVVGPICESSDVFGKAIDLNKAHRGDLFALRSA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEEECC
GAYGEIMASAYNCRALPKGYTSEELV
CCHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA