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The map label for this gene is hsdR [H]

Identifier: 150006177

GI number: 150006177

Start: 4559611

End: 4562439

Strand: Reverse

Name: hsdR [H]

Synonym: BVU_3688

Alternate gene names: 150006177

Gene position: 4562439-4559611 (Counterclockwise)

Preceding gene: 150006178

Following gene: 150006176

Centisome position: 88.36

GC content: 39.38

Gene sequence:

>2829_bases
ATGTCAACACAAAGTGAAGCGGCATTGGAAGCCGGACTGATAACCACTCTTCAACAAATGGACTATGAATATGTCCAAAT
TGTAGAAGAGGATAATTTGTATGCCAATTTCAAGCGGCAGTTGGAGGTTCATAACCGCAAACGGCTGGAGGAATATGGAC
GCAATGAGTTTACGACAGAAGAGTTTGAGAAGATTCTCATATACCTTGAAGGTGGTACTCGCTTTGAAAAGGCAAAGAAA
CTCCGTGATTTATATCCGCTTGATACGGCTGATGGACAGCGTATATGGGTGGAATTTCTAAATAGGCAACAGTGGTGTCA
GAATGAATTTCAGGTTTCCAACCAAATCACAGTGGAAGGACGTAAAAAATGCCGTTATGATATGACGATCCTAATCAATG
GTTTGCCACTTGTGCAGATTGAATTGAAACGTCGTGGCGTGGAACTTAAACAGGCATACAACCAAATACAGCGTTATCAC
AAGACTTCGTTTCACGGATTGTTTGATTATATCCAGTTGTTTGTTATATCCAATGGCGTTAACACTCGCTATTTTGCCAA
TAATCCAAATAGTGGGTATAAGTTCACATTCAACTGGACAGATGCCGCCAATCATCCGTTCAATGAATTGGACAAGTTTG
CCGTATTCTTCTTGGAAAAATGTACGCTTGGCAAAATCATAGGAAAGTATATTGTGCTGCATGAGGGCGACAAGTGCTTG
ATGGTACTTCGTCCTTACCAATTCTATGCGGTAGAGAAGATTTTGGATCGTGTACAAAACTCCAATGATAATGGTTATAT
CTGGCATACAACAGGTGCCGGAAAAACATTGACCTCATTCAAGGCTGCACAACTTGTATCAGAATTGGATGATGTGGATA
AGGTGATGTTTGTTGTTGACCGTCATGATCTCGATACTCAGACGCAATCGGAATACGAGGCTTTTGAGCCGGGTGCAGTG
GATAGTACCGACAATACGGATGAACTCGTGAAGCGACTTCAAAGCAATTCCAAAATCATCATAACCACCATTCAAAAACT
TAATGCGGCAGTTAGTAAGACGTGGTATAGCAACAAGATTGACGCTATCCGTCATTCACGCATCGTGATGATTTTTGATG
AGTGTCACCGTAGTCATTTTGGGGATAGCCATAAAAAGATTATGAAGTTCTTTGATAATGCCCAGATTTTTGGTTTTACG
GGAACACCTATCTTTACCGAAAATGCAGTGGATGGACATACGACAAAAGAAATTTTCGGCAATTGTCTTCATAAATATCT
CATCAAAGATGCTATTGCTGATGAAAATGTGCTTGGTTTCCTAGTGGAGTATTATCATGGTAACGAGATTGTAGATAACG
ATAACCAAACTCGTATGGAGGAGATTGCAAGATTTATCCTTAACAACTTCAATAAATCTACATTTGATGGAGAGTTTGAC
GCATTGTTTGCTGTACAGTCTGTTCCTATGCTTATCCGCTATTACAAGATTTTCAAATCATTGAATCCTAAAATCCGTAT
AGGTGCAGTATTTACATACGCAGCCAATAATAGTCAAGATGATGAACAGACTGGTATGGGTACGGGAAAATATGTCAGCG
AAAGTGTGGGCGAAGCAGATGAACTACAATCCATTATGGATGATTATAATGAAAACTACGGCACATCTTTTACAACAGAG
AACTTTCGTGCTTACTATGATGACATCAACCTGCGCATGAAAAAGAAGAAAGCGGATATGAAACCGCTTGACCTTTGTCT
TGTCGTGGGAATGTTCCTTACTGGTTTTGACAGTAAAAAACTGAACACACTTTATGTGGATAAGAATATGGAATATCACG
GTTTGCTGCAAGCATTCAGTCGTACCAACCGAGTGTTGAACGAGAAGAAACGATTCGGTAAAATCGTATGCTTCCGTGAT
CTGAAAAACAATGTTGATACGTCTATAAAACTGTTTAGCAATTCCGACAATCCTGAAGATATAGTACGTCCTCCGTTTGA
AAAAGTTAAGCATGAGTACAAGGGTTTGGCAACAGATTTTCTGCAAAAATATCCAACGCCAAGTAGTATAGACCTTCTGC
AAAGTGAAAATGACAAGAAGAATTTTGTACTTGCGTTCAGAGACATTATCCGTAAACATGCAGAAATCCAGATATACGAA
GATTACAGCGAGGATGCTGAAGACCTCGGTATGACCGAACAGCAGTTTAATGATTATAAGAGTAAATACCTCGACATTAC
GGTTGGTTTTATTGACCCACCTGCTACACAGTCAACTGTTGCGGAAGATCCTGTTCCATATGGCAATAGTCAAGGGCTGG
AAGACATTGATTTCTGTCTTGAACTTCTGCATAGTGATATTATCAATGTAGCGTATATTCTTGAACTCATTGCGGAACTT
GACCCATATAGCGATGATTATTCAGAAAAGCGCAAGCATATCCTTGATACAATGATTAAGGATGCTGGAATGCGAGGCAA
AGCAAAACTCATCGACGGCTTTATTCAAAAGAATGTAGATGAAGACAAGGAAAACTTCATGAATGGGCGCAATAGAGCAG
ATGGAACAAATGAATTAGAGGAACGTTTGAACCAATATATTGTGTCAGAACGCAATAAGGCTGTGAGTGATTTGGCGGAT
GATGAACAAATTTCTGCCGAAGTGCTTAATCTTTACATAAAAGAGTATGACTATTTACAAAAAGAACAGCCTGAAATTAT
ACAAAAGGCATTGAAAGAGAAGCATCTCGGTCTTATCAAAACCCGAAAGGCTTTGACGAGAATAATGGAAAGATTGCGTA
GTATTATAAAAACGTTTAATTGGGAATAA

Upstream 100 bases:

>100_bases
ATGGTTTTAGATGCATTTGCAATCTATGTAAAATCGAAAAGGTATTGGATGTCAGAATACTAATAGCATAAGTAGTAACT
ACTCATAATAGGGCAAGGAT

Downstream 100 bases:

>100_bases
GATATTATGAGCGAAGAATTACAGCAGAAACTCCGTGACCAACTTTGGGAGGTTGCAAATCGTTTGCGTGGCAATATGTC
GGCAAGTGACTTTATGTATT

Product: type I restriction enzyme EcoR124II R protein

Products: NA

Alternate protein names: Type I restriction enzyme R protein [H]

Number of amino acids: Translated: 942; Mature: 941

Protein sequence:

>942_residues
MSTQSEAALEAGLITTLQQMDYEYVQIVEEDNLYANFKRQLEVHNRKRLEEYGRNEFTTEEFEKILIYLEGGTRFEKAKK
LRDLYPLDTADGQRIWVEFLNRQQWCQNEFQVSNQITVEGRKKCRYDMTILINGLPLVQIELKRRGVELKQAYNQIQRYH
KTSFHGLFDYIQLFVISNGVNTRYFANNPNSGYKFTFNWTDAANHPFNELDKFAVFFLEKCTLGKIIGKYIVLHEGDKCL
MVLRPYQFYAVEKILDRVQNSNDNGYIWHTTGAGKTLTSFKAAQLVSELDDVDKVMFVVDRHDLDTQTQSEYEAFEPGAV
DSTDNTDELVKRLQSNSKIIITTIQKLNAAVSKTWYSNKIDAIRHSRIVMIFDECHRSHFGDSHKKIMKFFDNAQIFGFT
GTPIFTENAVDGHTTKEIFGNCLHKYLIKDAIADENVLGFLVEYYHGNEIVDNDNQTRMEEIARFILNNFNKSTFDGEFD
ALFAVQSVPMLIRYYKIFKSLNPKIRIGAVFTYAANNSQDDEQTGMGTGKYVSESVGEADELQSIMDDYNENYGTSFTTE
NFRAYYDDINLRMKKKKADMKPLDLCLVVGMFLTGFDSKKLNTLYVDKNMEYHGLLQAFSRTNRVLNEKKRFGKIVCFRD
LKNNVDTSIKLFSNSDNPEDIVRPPFEKVKHEYKGLATDFLQKYPTPSSIDLLQSENDKKNFVLAFRDIIRKHAEIQIYE
DYSEDAEDLGMTEQQFNDYKSKYLDITVGFIDPPATQSTVAEDPVPYGNSQGLEDIDFCLELLHSDIINVAYILELIAEL
DPYSDDYSEKRKHILDTMIKDAGMRGKAKLIDGFIQKNVDEDKENFMNGRNRADGTNELEERLNQYIVSERNKAVSDLAD
DEQISAEVLNLYIKEYDYLQKEQPEIIQKALKEKHLGLIKTRKALTRIMERLRSIIKTFNWE

Sequences:

>Translated_942_residues
MSTQSEAALEAGLITTLQQMDYEYVQIVEEDNLYANFKRQLEVHNRKRLEEYGRNEFTTEEFEKILIYLEGGTRFEKAKK
LRDLYPLDTADGQRIWVEFLNRQQWCQNEFQVSNQITVEGRKKCRYDMTILINGLPLVQIELKRRGVELKQAYNQIQRYH
KTSFHGLFDYIQLFVISNGVNTRYFANNPNSGYKFTFNWTDAANHPFNELDKFAVFFLEKCTLGKIIGKYIVLHEGDKCL
MVLRPYQFYAVEKILDRVQNSNDNGYIWHTTGAGKTLTSFKAAQLVSELDDVDKVMFVVDRHDLDTQTQSEYEAFEPGAV
DSTDNTDELVKRLQSNSKIIITTIQKLNAAVSKTWYSNKIDAIRHSRIVMIFDECHRSHFGDSHKKIMKFFDNAQIFGFT
GTPIFTENAVDGHTTKEIFGNCLHKYLIKDAIADENVLGFLVEYYHGNEIVDNDNQTRMEEIARFILNNFNKSTFDGEFD
ALFAVQSVPMLIRYYKIFKSLNPKIRIGAVFTYAANNSQDDEQTGMGTGKYVSESVGEADELQSIMDDYNENYGTSFTTE
NFRAYYDDINLRMKKKKADMKPLDLCLVVGMFLTGFDSKKLNTLYVDKNMEYHGLLQAFSRTNRVLNEKKRFGKIVCFRD
LKNNVDTSIKLFSNSDNPEDIVRPPFEKVKHEYKGLATDFLQKYPTPSSIDLLQSENDKKNFVLAFRDIIRKHAEIQIYE
DYSEDAEDLGMTEQQFNDYKSKYLDITVGFIDPPATQSTVAEDPVPYGNSQGLEDIDFCLELLHSDIINVAYILELIAEL
DPYSDDYSEKRKHILDTMIKDAGMRGKAKLIDGFIQKNVDEDKENFMNGRNRADGTNELEERLNQYIVSERNKAVSDLAD
DEQISAEVLNLYIKEYDYLQKEQPEIIQKALKEKHLGLIKTRKALTRIMERLRSIIKTFNWE
>Mature_941_residues
STQSEAALEAGLITTLQQMDYEYVQIVEEDNLYANFKRQLEVHNRKRLEEYGRNEFTTEEFEKILIYLEGGTRFEKAKKL
RDLYPLDTADGQRIWVEFLNRQQWCQNEFQVSNQITVEGRKKCRYDMTILINGLPLVQIELKRRGVELKQAYNQIQRYHK
TSFHGLFDYIQLFVISNGVNTRYFANNPNSGYKFTFNWTDAANHPFNELDKFAVFFLEKCTLGKIIGKYIVLHEGDKCLM
VLRPYQFYAVEKILDRVQNSNDNGYIWHTTGAGKTLTSFKAAQLVSELDDVDKVMFVVDRHDLDTQTQSEYEAFEPGAVD
STDNTDELVKRLQSNSKIIITTIQKLNAAVSKTWYSNKIDAIRHSRIVMIFDECHRSHFGDSHKKIMKFFDNAQIFGFTG
TPIFTENAVDGHTTKEIFGNCLHKYLIKDAIADENVLGFLVEYYHGNEIVDNDNQTRMEEIARFILNNFNKSTFDGEFDA
LFAVQSVPMLIRYYKIFKSLNPKIRIGAVFTYAANNSQDDEQTGMGTGKYVSESVGEADELQSIMDDYNENYGTSFTTEN
FRAYYDDINLRMKKKKADMKPLDLCLVVGMFLTGFDSKKLNTLYVDKNMEYHGLLQAFSRTNRVLNEKKRFGKIVCFRDL
KNNVDTSIKLFSNSDNPEDIVRPPFEKVKHEYKGLATDFLQKYPTPSSIDLLQSENDKKNFVLAFRDIIRKHAEIQIYED
YSEDAEDLGMTEQQFNDYKSKYLDITVGFIDPPATQSTVAEDPVPYGNSQGLEDIDFCLELLHSDIINVAYILELIAELD
PYSDDYSEKRKHILDTMIKDAGMRGKAKLIDGFIQKNVDEDKENFMNGRNRADGTNELEERLNQYIVSERNKAVSDLADD
EQISAEVLNLYIKEYDYLQKEQPEIIQKALKEKHLGLIKTRKALTRIMERLRSIIKTFNWE

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR014021
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409
- InterPro:   IPR022625 [H]

Pfam domain/function: PF12008 EcoR124_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 109346; Mature: 109215

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQSEAALEAGLITTLQQMDYEYVQIVEEDNLYANFKRQLEVHNRKRLEEYGRNEFTTE
CCCCHHHHHHHHHHHHHHHCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EFEKILIYLEGGTRFEKAKKLRDLYPLDTADGQRIWVEFLNRQQWCQNEFQVSNQITVEG
HHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
RKKCRYDMTILINGLPLVQIELKRRGVELKQAYNQIQRYHKTSFHGLFDYIQLFVISNGV
CCCCCEEEEEEECCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTRYFANNPNSGYKFTFNWTDAANHPFNELDKFAVFFLEKCTLGKIIGKYIVLHEGDKCL
CCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEE
MVLRPYQFYAVEKILDRVQNSNDNGYIWHTTGAGKTLTSFKAAQLVSELDDVDKVMFVVD
EEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
RHDLDTQTQSEYEAFEPGAVDSTDNTDELVKRLQSNSKIIITTIQKLNAAVSKTWYSNKI
CCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCH
DAIRHSRIVMIFDECHRSHFGDSHKKIMKFFDNAQIFGFTGTPIFTENAVDGHTTKEIFG
HHHHHCCEEEEHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHH
NCLHKYLIKDAIADENVLGFLVEYYHGNEIVDNDNQTRMEEIARFILNNFNKSTFDGEFD
HHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHH
ALFAVQSVPMLIRYYKIFKSLNPKIRIGAVFTYAANNSQDDEQTGMGTGKYVSESVGEAD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHCCCCCHHHHHHCCCHH
ELQSIMDDYNENYGTSFTTENFRAYYDDINLRMKKKKADMKPLDLCLVVGMFLTGFDSKK
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCCCC
LNTLYVDKNMEYHGLLQAFSRTNRVLNEKKRFGKIVCFRDLKNNVDTSIKLFSNSDNPED
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCCCCEEEEEECCCCCHH
IVRPPFEKVKHEYKGLATDFLQKYPTPSSIDLLQSENDKKNFVLAFRDIIRKHAEIQIYE
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEC
DYSEDAEDLGMTEQQFNDYKSKYLDITVGFIDPPATQSTVAEDPVPYGNSQGLEDIDFCL
CCCCCHHHCCCCHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ELLHSDIINVAYILELIAELDPYSDDYSEKRKHILDTMIKDAGMRGKAKLIDGFIQKNVD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
EDKENFMNGRNRADGTNELEERLNQYIVSERNKAVSDLADDEQISAEVLNLYIKEYDYLQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KEQPEIIQKALKEKHLGLIKTRKALTRIMERLRSIIKTFNWE
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STQSEAALEAGLITTLQQMDYEYVQIVEEDNLYANFKRQLEVHNRKRLEEYGRNEFTTE
CCCHHHHHHHHHHHHHHHCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EFEKILIYLEGGTRFEKAKKLRDLYPLDTADGQRIWVEFLNRQQWCQNEFQVSNQITVEG
HHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
RKKCRYDMTILINGLPLVQIELKRRGVELKQAYNQIQRYHKTSFHGLFDYIQLFVISNGV
CCCCCEEEEEEECCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTRYFANNPNSGYKFTFNWTDAANHPFNELDKFAVFFLEKCTLGKIIGKYIVLHEGDKCL
CCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEE
MVLRPYQFYAVEKILDRVQNSNDNGYIWHTTGAGKTLTSFKAAQLVSELDDVDKVMFVVD
EEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
RHDLDTQTQSEYEAFEPGAVDSTDNTDELVKRLQSNSKIIITTIQKLNAAVSKTWYSNKI
CCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCH
DAIRHSRIVMIFDECHRSHFGDSHKKIMKFFDNAQIFGFTGTPIFTENAVDGHTTKEIFG
HHHHHCCEEEEHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHH
NCLHKYLIKDAIADENVLGFLVEYYHGNEIVDNDNQTRMEEIARFILNNFNKSTFDGEFD
HHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHH
ALFAVQSVPMLIRYYKIFKSLNPKIRIGAVFTYAANNSQDDEQTGMGTGKYVSESVGEAD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHCCCCCHHHHHHCCCHH
ELQSIMDDYNENYGTSFTTENFRAYYDDINLRMKKKKADMKPLDLCLVVGMFLTGFDSKK
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCCCC
LNTLYVDKNMEYHGLLQAFSRTNRVLNEKKRFGKIVCFRDLKNNVDTSIKLFSNSDNPED
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCCCCEEEEEECCCCCHH
IVRPPFEKVKHEYKGLATDFLQKYPTPSSIDLLQSENDKKNFVLAFRDIIRKHAEIQIYE
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEC
DYSEDAEDLGMTEQQFNDYKSKYLDITVGFIDPPATQSTVAEDPVPYGNSQGLEDIDFCL
CCCCCHHHCCCCHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ELLHSDIINVAYILELIAELDPYSDDYSEKRKHILDTMIKDAGMRGKAKLIDGFIQKNVD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
EDKENFMNGRNRADGTNELEERLNQYIVSERNKAVSDLADDEQISAEVLNLYIKEYDYLQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KEQPEIIQKALKEKHLGLIKTRKALTRIMERLRSIIKTFNWE
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA