Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 150005230

GI number: 150005230

Start: 3442537

End: 3443577

Strand: Direct

Name: corA [H]

Synonym: BVU_2701

Alternate gene names: 150005230

Gene position: 3442537-3443577 (Clockwise)

Preceding gene: 150005229

Following gene: 150005232

Centisome position: 66.67

GC content: 36.7

Gene sequence:

>1041_bases
ATGGCGAAGAATAATTTACTAAGTGAGCAACTTGCTTATATTGGTGTCAGTTGTACCCCTACGCATCTGCATTTGTGCAG
TTATAATGCTGAAAGTATTTGTATGAAGGATGGGAAAGATATAGATAGTTTAATCCCTTATTTGAATAAGAATGCTATAA
ACTGGATACAAATTCATGGCTTTCAGAATACGGAGGTCATACAGCATGTCTGTCAGAATTTTAATGTCGACTTTTTGACG
ATACAAGATATTTTGAACTCCGACCATCAGACCAAGATAGAACAGCATGATACATATAATGTAGTGATTTTGAAGTTACT
TTTTTCTAATGATGATGGCTATGTACCACAACAAATAGCCATTGTGCAAGGTGGAAATTATCTGTTGACTTTTATGGAAA
AGGAAACAGACTTTCTGAATGATATAAATACGGCATTGGAAAAGAATGTGTTGAAAATACGTAGCCGGCAGTCTGATTTC
CTGCTCAGTGTTATTCTAAACAGTGTGATGGCCAGCTTTATATCCATTATTTCGGAATTGGAAGACGGATTAGAGGATTT
AGAAGAGCAATTGCTTTCGCCGGAACAGGCTGATATGCTCGGTATTGAAAATATACAGCAATACCGCCGTAATTTTCGTG
TAATAAAGAAATGTATTTTACCATTAAAGGAGGAAATCAGCAAGTTGTTGCATCCGATCGATAATGATTTGTTGCACAAA
GCAAGCCGTCCTTTCTTTAATGATGTCAATGATCATTTGCAGTTTGTATTGCAAACTTTAGATGGTTGCCGTGACATGAT
TTCAGCTTTGGTAGATATTTACCTTTCCAATAATGACCGACGGATGAACAGCATCATGAAACAGCTGACTGTTGTTTCTA
CTATATTTATTCCGTTGACTTTTCTGGCAGGAATCTGGGGAATGAATTTCCAATGGATGCCTGAACTGGGATGGCGGTAT
GGCTATGTATTTGCATGGACATTGATGTTGATACTAGTAGCAGTTATCTACTTCTATTTTAAGCGTAAAAAATGGTATTG
A

Upstream 100 bases:

>100_bases
GGGATCAGTTTGAAAACTTGGGGGAATCTTTTCTTTTTTGTAGAGAACACAGTTGAACTTTTAAAAAAGAATTATATTTG
TATTATTCATTACTGAAACT

Downstream 100 bases:

>100_bases
TGAGAGAGGATGGATGGGATTTACTTAAATGTGAATCCCATATTCATGTTTTACTTCATTCATTACAAAGGTGCTTTCCA
GTGAACCCAAACTGTCAATC

Product: Mg2+/Co2+ transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAKNNLLSEQLAYIGVSCTPTHLHLCSYNAESICMKDGKDIDSLIPYLNKNAINWIQIHGFQNTEVIQHVCQNFNVDFLT
IQDILNSDHQTKIEQHDTYNVVILKLLFSNDDGYVPQQIAIVQGGNYLLTFMEKETDFLNDINTALEKNVLKIRSRQSDF
LLSVILNSVMASFISIISELEDGLEDLEEQLLSPEQADMLGIENIQQYRRNFRVIKKCILPLKEEISKLLHPIDNDLLHK
ASRPFFNDVNDHLQFVLQTLDGCRDMISALVDIYLSNNDRRMNSIMKQLTVVSTIFIPLTFLAGIWGMNFQWMPELGWRY
GYVFAWTLMLILVAVIYFYFKRKKWY

Sequences:

>Translated_346_residues
MAKNNLLSEQLAYIGVSCTPTHLHLCSYNAESICMKDGKDIDSLIPYLNKNAINWIQIHGFQNTEVIQHVCQNFNVDFLT
IQDILNSDHQTKIEQHDTYNVVILKLLFSNDDGYVPQQIAIVQGGNYLLTFMEKETDFLNDINTALEKNVLKIRSRQSDF
LLSVILNSVMASFISIISELEDGLEDLEEQLLSPEQADMLGIENIQQYRRNFRVIKKCILPLKEEISKLLHPIDNDLLHK
ASRPFFNDVNDHLQFVLQTLDGCRDMISALVDIYLSNNDRRMNSIMKQLTVVSTIFIPLTFLAGIWGMNFQWMPELGWRY
GYVFAWTLMLILVAVIYFYFKRKKWY
>Mature_345_residues
AKNNLLSEQLAYIGVSCTPTHLHLCSYNAESICMKDGKDIDSLIPYLNKNAINWIQIHGFQNTEVIQHVCQNFNVDFLTI
QDILNSDHQTKIEQHDTYNVVILKLLFSNDDGYVPQQIAIVQGGNYLLTFMEKETDFLNDINTALEKNVLKIRSRQSDFL
LSVILNSVMASFISIISELEDGLEDLEEQLLSPEQADMLGIENIQQYRRNFRVIKKCILPLKEEISKLLHPIDNDLLHKA
SRPFFNDVNDHLQFVLQTLDGCRDMISALVDIYLSNNDRRMNSIMKQLTVVSTIFIPLTFLAGIWGMNFQWMPELGWRYG
YVFAWTLMLILVAVIYFYFKRKKWY

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=134, Percent_Identity=34.3283582089552, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40192; Mature: 40061

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNNLLSEQLAYIGVSCTPTHLHLCSYNAESICMKDGKDIDSLIPYLNKNAINWIQIHG
CCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHCCCCCCEEEEEC
FQNTEVIQHVCQNFNVDFLTIQDILNSDHQTKIEQHDTYNVVILKLLFSNDDGYVPQQIA
CCCHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHCCCHHHHHEEEECCCCCCCCCCEEE
IVQGGNYLLTFMEKETDFLNDINTALEKNVLKIRSRQSDFLLSVILNSVMASFISIISEL
EEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EDGLEDLEEQLLSPEQADMLGIENIQQYRRNFRVIKKCILPLKEEISKLLHPIDNDLLHK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ASRPFFNDVNDHLQFVLQTLDGCRDMISALVDIYLSNNDRRMNSIMKQLTVVSTIFIPLT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FLAGIWGMNFQWMPELGWRYGYVFAWTLMLILVAVIYFYFKRKKWY
HHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKNNLLSEQLAYIGVSCTPTHLHLCSYNAESICMKDGKDIDSLIPYLNKNAINWIQIHG
CCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHCCCCCCEEEEEC
FQNTEVIQHVCQNFNVDFLTIQDILNSDHQTKIEQHDTYNVVILKLLFSNDDGYVPQQIA
CCCHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHCCCHHHHHEEEECCCCCCCCCCEEE
IVQGGNYLLTFMEKETDFLNDINTALEKNVLKIRSRQSDFLLSVILNSVMASFISIISEL
EEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EDGLEDLEEQLLSPEQADMLGIENIQQYRRNFRVIKKCILPLKEEISKLLHPIDNDLLHK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ASRPFFNDVNDHLQFVLQTLDGCRDMISALVDIYLSNNDRRMNSIMKQLTVVSTIFIPLT
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FLAGIWGMNFQWMPELGWRYGYVFAWTLMLILVAVIYFYFKRKKWY
HHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]