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The map label for this gene is xpt

Identifier: 150005067

GI number: 150005067

Start: 3236281

End: 3236847

Strand: Reverse

Name: xpt

Synonym: BVU_2532

Alternate gene names: 150005067

Gene position: 3236847-3236281 (Counterclockwise)

Preceding gene: 150005070

Following gene: 150005066

Centisome position: 62.69

GC content: 41.27

Gene sequence:

>567_bases
ATGAAAGCATTAAAAGAACGCATTTTACGGGACGGAAAATGTTTCGAAGGAGGAATACTGAAAGTAGACAATTTCATCAA
TCACCAAATGGATCCTATCCTCATGAAATCCATTGCTGTAGAATTTGTACGCCGTTTCGCCTCTACCAATATCAATAAAG
TTATGACCATCGAAGCCAGTGGTATAGCTCCCGCCATCATGGTAGGCTACTTACTGGAACTTCCTGTTGTCTTCGCCAAG
AAAAAGAAACCCGTCACAATGGAAAATATGCTCACCACCAGTGTATATTCATTTACTAAAGACCGTTCTTATGATGTATG
TGTCAGTAAAGATTTCCTGTCCAAAGGAGACCGTGTTCTTTTTATTGACGACTTTCTCGCCAACGGCAATGCAGCCAAGG
GTATCATCGATTTGGTAGAAAAAGCCGGAGCCGAACTGTCCGGAATGGGATTCATCATCGAAAAAGCATTCCAACATGGC
GGAGATTATTTGCGTAATGCAGGTATCCGCGTAGAATCATTGGCCATCATTGAAAGTCTGGACAATTGTGAAATCAAAAT
AAGATAA

Upstream 100 bases:

>100_bases
TCATTAAGTAAATAGGCTTCTGTAGAGATAGTTGTACAAACGTTTGGCATAATGCAGCAAAATACGTACTTTTGCGACTC
ATTTATAAAATACAGTTTGA

Downstream 100 bases:

>100_bases
CCCCATGCAGGAATCTCAAACCGCCCAATCCAATACCGGACTGATTTACGGATTGAACGACCGCCCCCCTGTACGAGAGG
CCATTTTTGCTGCCATACAG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKALKERILRDGKCFEGGILKVDNFINHQMDPILMKSIAVEFVRRFASTNINKVMTIEASGIAPAIMVGYLLELPVVFAK
KKKPVTMENMLTTSVYSFTKDRSYDVCVSKDFLSKGDRVLFIDDFLANGNAAKGIIDLVEKAGAELSGMGFIIEKAFQHG
GDYLRNAGIRVESLAIIESLDNCEIKIR

Sequences:

>Translated_188_residues
MKALKERILRDGKCFEGGILKVDNFINHQMDPILMKSIAVEFVRRFASTNINKVMTIEASGIAPAIMVGYLLELPVVFAK
KKKPVTMENMLTTSVYSFTKDRSYDVCVSKDFLSKGDRVLFIDDFLANGNAAKGIIDLVEKAGAELSGMGFIIEKAFQHG
GDYLRNAGIRVESLAIIESLDNCEIKIR
>Mature_188_residues
MKALKERILRDGKCFEGGILKVDNFINHQMDPILMKSIAVEFVRRFASTNINKVMTIEASGIAPAIMVGYLLELPVVFAK
KKKPVTMENMLTTSVYSFTKDRSYDVCVSKDFLSKGDRVLFIDDFLANGNAAKGIIDLVEKAGAELSGMGFIIEKAFQHG
GDYLRNAGIRVESLAIIESLDNCEIKIR

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_BACV8 (A6L3C5)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299811.1
- ProteinModelPortal:   A6L3C5
- SMR:   A6L3C5
- STRING:   A6L3C5
- GeneID:   5303496
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2532
- NMPDR:   fig|435590.6.peg.2374
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   QYFNVPV
- ProtClustDB:   PRK09219
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 20888; Mature: 20888

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALKERILRDGKCFEGGILKVDNFINHQMDPILMKSIAVEFVRRFASTNINKVMTIEAS
CHHHHHHHHCCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GIAPAIMVGYLLELPVVFAKKKKPVTMENMLTTSVYSFTKDRSYDVCVSKDFLSKGDRVL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHCCCCEEE
FIDDFLANGNAAKGIIDLVEKAGAELSGMGFIIEKAFQHGGDYLRNAGIRVESLAIIESL
EEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHC
DNCEIKIR
CCCEEEEC
>Mature Secondary Structure
MKALKERILRDGKCFEGGILKVDNFINHQMDPILMKSIAVEFVRRFASTNINKVMTIEAS
CHHHHHHHHCCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GIAPAIMVGYLLELPVVFAKKKKPVTMENMLTTSVYSFTKDRSYDVCVSKDFLSKGDRVL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHCCCCEEE
FIDDFLANGNAAKGIIDLVEKAGAELSGMGFIIEKAFQHGGDYLRNAGIRVESLAIIESL
EEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHC
DNCEIKIR
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA