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The map label for this gene is xanP [H]

Identifier: 150005066

GI number: 150005066

Start: 3234945

End: 3236276

Strand: Reverse

Name: xanP [H]

Synonym: BVU_2531

Alternate gene names: 150005066

Gene position: 3236276-3234945 (Counterclockwise)

Preceding gene: 150005067

Following gene: 150005065

Centisome position: 62.68

GC content: 43.69

Gene sequence:

>1332_bases
ATGCAGGAATCTCAAACCGCCCAATCCAATACCGGACTGATTTACGGATTGAACGACCGCCCCCCTGTACGAGAGGCCAT
TTTTGCTGCCATACAGCATTTGCTTGCTATTTTTGTAGCCATCATCACTCCGCCTCTTATCATCGCTGGAGCATTAAAAC
TGGATTTGGAAACCACCAGTTTCCTAGTATCCATGTCTCTCTTTGCCTCAGGTATTTCTACCTTTATCCAATGCAGACGG
ATAGGAGGCATCGGCACCGGTCTCTTATGTATCCAAGGAACCAGTTTTTCATTTATCGGTCCCATCATCTCGGCAGGTAT
GCTGGGCGGACTTCCACTGATTTTCGGCACTTGCATCGTGGCATCATCTGTAGAGATGGTCATCAGCCGCATCTTAAAAT
ATACCCGTAAAATAATCACCCCTCTGGTATCGGGCATTGTAGTCACTTTGATTGGAATGAGCCTGATAAAAGTAGGTATC
ACAGCTTGTGGCGGGGGTGTTTCCGCCCAAAGCAACGGCACTTTCGGAAGTTTTGAGAATCTAGGTCTAGCTCTGCTGGT
ACTTATCCTCATTATCCTTTTTAATAGAAGTTCCAACCGCTACCTACGTATGAGTTCCATCGTTATCGGTCTGATTATAG
GATATTTAGTTGCCTGGGGACTCGGTAGAATTGATTTCTCGGCAGTACAAAGTTTTGGTGGTTTCAATATTCCCCTCCCA
TTTAAATACGGACTGGATTTCGACTTTTCCGCATTCATAGCTTTGGGGTTAGTATTCTTGATAACAGCCATAGAAGCCTA
TGGAGACATTACTGCCAACTCACTGATATCAGGAGAACCTGTAGAAGGAAAAACATTCATCAAACGTGCTTCGGGAGGAA
TTTTGGCAGACGGATTCAATTCGATGATGGCAGGTATTCTCAACTCTTTTCCAAACTCCGTTTTCGCGCAAAATAACGGT
ATGATACAACTGACAGGAGTAGCCAGCCGATATGTAGGCTATTACATTGCAGGTTTTCTTATTCTATTAGGATTATTTCC
CAGTGTAGGATTAATTTTCTCCCTAATGCCCGAACCTGTATTGGGAGGCGCTACTTTACTGATGTTCGGAACAGTAGCTT
CAGCAGGCATTCGTATTATCGCAGCACAGAAGATCAACCGGAAAGCAACATTAGTCATCGCACTTAGTTTCGCTTTAGGT
TTAAGTGTAGAAATGGTTCCTGAAATACTATGTCAATTTCCGGAATCAATAAAGAATATTTTCTCATCCGGCATTACAAC
AGGCGGAGTGACTGCCATCATTTCAAATGCACTGATACGGATGAAAGAGTAA

Upstream 100 bases:

>100_bases
CAACATGGCGGAGATTATTTGCGTAATGCAGGTATCCGCGTAGAATCATTGGCCATCATTGAAAGTCTGGACAATTGTGA
AATCAAAATAAGATAACCCC

Downstream 100 bases:

>100_bases
AAACAAGTAATTTTCTCATAATTTGGAACTAAAGCATTAACTTTCTTTGCAAATCAGCCAAGAAAGGGAGAATAATATAT
ATCTTTGTTCCAAAATATGA

Product: putative purine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQESQTAQSNTGLIYGLNDRPPVREAIFAAIQHLLAIFVAIITPPLIIAGALKLDLETTSFLVSMSLFASGISTFIQCRR
IGGIGTGLLCIQGTSFSFIGPIISAGMLGGLPLIFGTCIVASSVEMVISRILKYTRKIITPLVSGIVVTLIGMSLIKVGI
TACGGGVSAQSNGTFGSFENLGLALLVLILIILFNRSSNRYLRMSSIVIGLIIGYLVAWGLGRIDFSAVQSFGGFNIPLP
FKYGLDFDFSAFIALGLVFLITAIEAYGDITANSLISGEPVEGKTFIKRASGGILADGFNSMMAGILNSFPNSVFAQNNG
MIQLTGVASRYVGYYIAGFLILLGLFPSVGLIFSLMPEPVLGGATLLMFGTVASAGIRIIAAQKINRKATLVIALSFALG
LSVEMVPEILCQFPESIKNIFSSGITTGGVTAIISNALIRMKE

Sequences:

>Translated_443_residues
MQESQTAQSNTGLIYGLNDRPPVREAIFAAIQHLLAIFVAIITPPLIIAGALKLDLETTSFLVSMSLFASGISTFIQCRR
IGGIGTGLLCIQGTSFSFIGPIISAGMLGGLPLIFGTCIVASSVEMVISRILKYTRKIITPLVSGIVVTLIGMSLIKVGI
TACGGGVSAQSNGTFGSFENLGLALLVLILIILFNRSSNRYLRMSSIVIGLIIGYLVAWGLGRIDFSAVQSFGGFNIPLP
FKYGLDFDFSAFIALGLVFLITAIEAYGDITANSLISGEPVEGKTFIKRASGGILADGFNSMMAGILNSFPNSVFAQNNG
MIQLTGVASRYVGYYIAGFLILLGLFPSVGLIFSLMPEPVLGGATLLMFGTVASAGIRIIAAQKINRKATLVIALSFALG
LSVEMVPEILCQFPESIKNIFSSGITTGGVTAIISNALIRMKE
>Mature_443_residues
MQESQTAQSNTGLIYGLNDRPPVREAIFAAIQHLLAIFVAIITPPLIIAGALKLDLETTSFLVSMSLFASGISTFIQCRR
IGGIGTGLLCIQGTSFSFIGPIISAGMLGGLPLIFGTCIVASSVEMVISRILKYTRKIITPLVSGIVVTLIGMSLIKVGI
TACGGGVSAQSNGTFGSFENLGLALLVLILIILFNRSSNRYLRMSSIVIGLIIGYLVAWGLGRIDFSAVQSFGGFNIPLP
FKYGLDFDFSAFIALGLVFLITAIEAYGDITANSLISGEPVEGKTFIKRASGGILADGFNSMMAGILNSFPNSVFAQNNG
MIQLTGVASRYVGYYIAGFLILLGLFPSVGLIFSLMPEPVLGGATLLMFGTVASAGIRIIAAQKINRKATLVIALSFALG
LSVEMVPEILCQFPESIKNIFSSGITTGGVTAIISNALIRMKE

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=479, Percent_Identity=24.6346555323591, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI40316845, Length=479, Percent_Identity=24.6346555323591, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI44680145, Length=454, Percent_Identity=25.1101321585903, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI44680143, Length=458, Percent_Identity=24.8908296943231, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1790087, Length=451, Percent_Identity=52.1064301552106, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI87082178, Length=442, Percent_Identity=47.5113122171946, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI87082181, Length=433, Percent_Identity=30.4849884526559, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1788843, Length=379, Percent_Identity=25.065963060686, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081818, Length=449, Percent_Identity=25.6124721603563, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356175, Length=485, Percent_Identity=23.9175257731959, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46658; Mature: 46658

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESQTAQSNTGLIYGLNDRPPVREAIFAAIQHLLAIFVAIITPPLIIAGALKLDLETTS
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECHHHH
FLVSMSLFASGISTFIQCRRIGGIGTGLLCIQGTSFSFIGPIISAGMLGGLPLIFGTCIV
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHH
ASSVEMVISRILKYTRKIITPLVSGIVVTLIGMSLIKVGITACGGGVSAQSNGTFGSFEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
LGLALLVLILIILFNRSSNRYLRMSSIVIGLIIGYLVAWGLGRIDFSAVQSFGGFNIPLP
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCC
FKYGLDFDFSAFIALGLVFLITAIEAYGDITANSLISGEPVEGKTFIKRASGGILADGFN
EECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCCCEECCHH
SMMAGILNSFPNSVFAQNNGMIQLTGVASRYVGYYIAGFLILLGLFPSVGLIFSLMPEPV
HHHHHHHHHCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LGGATLLMFGTVASAGIRIIAAQKINRKATLVIALSFALGLSVEMVPEILCQFPESIKNI
CCCHHHHHHHHHHHCCEEEEEEHHCCCCEEEEEEEHHHHCCCHHHHHHHHHHCHHHHHHH
FSSGITTGGVTAIISNALIRMKE
HHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQESQTAQSNTGLIYGLNDRPPVREAIFAAIQHLLAIFVAIITPPLIIAGALKLDLETTS
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECHHHH
FLVSMSLFASGISTFIQCRRIGGIGTGLLCIQGTSFSFIGPIISAGMLGGLPLIFGTCIV
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHH
ASSVEMVISRILKYTRKIITPLVSGIVVTLIGMSLIKVGITACGGGVSAQSNGTFGSFEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
LGLALLVLILIILFNRSSNRYLRMSSIVIGLIIGYLVAWGLGRIDFSAVQSFGGFNIPLP
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCC
FKYGLDFDFSAFIALGLVFLITAIEAYGDITANSLISGEPVEGKTFIKRASGGILADGFN
EECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCCCEECCHH
SMMAGILNSFPNSVFAQNNGMIQLTGVASRYVGYYIAGFLILLGLFPSVGLIFSLMPEPV
HHHHHHHHHCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LGGATLLMFGTVASAGIRIIAAQKINRKATLVIALSFALGLSVEMVPEILCQFPESIKNI
CCCHHHHHHHHHHHCCEEEEEEHHCCCCEEEEEEEHHHHCCCHHHHHHHHHHCHHHHHHH
FSSGITTGGVTAIISNALIRMKE
HHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]