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The map label for this gene is paaK [H]

Identifier: 150004813

GI number: 150004813

Start: 2943512

End: 2944813

Strand: Direct

Name: paaK [H]

Synonym: BVU_2276

Alternate gene names: 150004813

Gene position: 2943512-2944813 (Clockwise)

Preceding gene: 150004812

Following gene: 150004814

Centisome position: 57.01

GC content: 44.93

Gene sequence:

>1302_bases
ATGATTTGGAATAAAAATAAAGAGTGCATGAGTCGGGACGAGATGAGCGCTCTGCAGGGAAAACGTCTGAACAAGTTGGT
GAACTTGGTTTATCATAATGTTCCTTTTTATCGTAACAAGATGCAGGAGATGGATTTGTCTCCGGATGATATCCAGACTA
TCGAAGATATCGTAAAACTTCCTTTTACTACCAAGCAGGATTTACGTGATAATTATCCATATGGTCTTCAGGCTGCTCCT
GCTTCGGAAATTGTACGTGTGCACGCTTCTTCGGGAACAACCGGGAATCCTACCATTGTGGGATATACGCGTCGTGACTT
GTCTGTATGGTCCGAAGTGATGTCACGTTGTCTTTCAGCATACGGGGTTACCCGTAATGATACCTTTTCTGTCAGTTATG
GCTATGGCTTGTTTACAGGCGGGTTGGGCGCACATTATGGGGTGGAGAATCTGGGGGCGACTGTTATCCCGGCTTCTACA
GGAAATACGGAAAAGCATGTCCGTCTGATTCGCGACTTGGGTATAACGGGGATTGCCTGTACTCCTTCATACGCTCTTTA
TCTGGCAGAAGTGGTGGAACGTATGGGATTGACCAAGAATGATATCAATCTCCGTATCGGAGCTTTCGGAGCCGAGCCAT
GGACGGAAAGTATGCGTAAGGAGATAGAAGAGCGGCTGGGATTGAAAGGGTATAATATTTATGGATTAAGTGAGATTATG
GGACCCGGTGTTTCCTACGAATGTCAGGAGCAACATGGTTCGCATATCAATGAGGATCATTTTTATCCTGAAATCATTAA
TCCTGAAACGCTGGAACGTCTTCCGGATGGAGAAGTGGGAGAATTGGTGTTTACTACCTTGACAAAGGAGGGGATGCCGT
TATTGCGTTATCGTACGAAGGACTTGACTTCCCTGATGGAGGGTGAATGTCCGTGTGGAAGAACCAATATCCGTATGTCG
GGTATTGTAGGCCGTAGTGACGATATGCTTATTATCCGTGGCATCAATGTTTTCCCTTCTCAGGTGGAAAGTGTTATTTT
GGATATGCCTCAGTTTGAACCTCAGTATATGCTGGTGGTGGATAGGAAGAATAATCTCGACTCTTTGCAAGTACAAGTGG
AAGTCCGCAAAGACTTCTTCTCGGATGATATGGGAAGTATGCTTGCCATGAAGAAAGCGTTGAGCGACAAACTGAAAAGT
GTCCTTTCCATCAGTGCCGAAGTGAAGCTGATGGAACCTAATAGCATTGCCCGTAGTGAAGGTAAGAGTAAACGTGTGAT
AGACAATCGGATTTTAAAATAA

Upstream 100 bases:

>100_bases
CATTGAAAATAATGTGCTAATAGGATAATGTGCCGATTGCCATACAGTGGGTTTGTGTGCCAGTACATTGGCAGATTAGC
ACATTGAAAAATTATTTATT

Downstream 100 bases:

>100_bases
AAAAGTATGCGATATGACAATCAAGCAATTATCTGTTTTTCTGGAAAACAAAACCGGAAGAATAAATGACGTAACCAAGA
CATTGGCAAAGTATGATATC

Product: phenylacetate-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIWNKNKECMSRDEMSALQGKRLNKLVNLVYHNVPFYRNKMQEMDLSPDDIQTIEDIVKLPFTTKQDLRDNYPYGLQAAP
ASEIVRVHASSGTTGNPTIVGYTRRDLSVWSEVMSRCLSAYGVTRNDTFSVSYGYGLFTGGLGAHYGVENLGATVIPAST
GNTEKHVRLIRDLGITGIACTPSYALYLAEVVERMGLTKNDINLRIGAFGAEPWTESMRKEIEERLGLKGYNIYGLSEIM
GPGVSYECQEQHGSHINEDHFYPEIINPETLERLPDGEVGELVFTTLTKEGMPLLRYRTKDLTSLMEGECPCGRTNIRMS
GIVGRSDDMLIIRGINVFPSQVESVILDMPQFEPQYMLVVDRKNNLDSLQVQVEVRKDFFSDDMGSMLAMKKALSDKLKS
VLSISAEVKLMEPNSIARSEGKSKRVIDNRILK

Sequences:

>Translated_433_residues
MIWNKNKECMSRDEMSALQGKRLNKLVNLVYHNVPFYRNKMQEMDLSPDDIQTIEDIVKLPFTTKQDLRDNYPYGLQAAP
ASEIVRVHASSGTTGNPTIVGYTRRDLSVWSEVMSRCLSAYGVTRNDTFSVSYGYGLFTGGLGAHYGVENLGATVIPAST
GNTEKHVRLIRDLGITGIACTPSYALYLAEVVERMGLTKNDINLRIGAFGAEPWTESMRKEIEERLGLKGYNIYGLSEIM
GPGVSYECQEQHGSHINEDHFYPEIINPETLERLPDGEVGELVFTTLTKEGMPLLRYRTKDLTSLMEGECPCGRTNIRMS
GIVGRSDDMLIIRGINVFPSQVESVILDMPQFEPQYMLVVDRKNNLDSLQVQVEVRKDFFSDDMGSMLAMKKALSDKLKS
VLSISAEVKLMEPNSIARSEGKSKRVIDNRILK
>Mature_433_residues
MIWNKNKECMSRDEMSALQGKRLNKLVNLVYHNVPFYRNKMQEMDLSPDDIQTIEDIVKLPFTTKQDLRDNYPYGLQAAP
ASEIVRVHASSGTTGNPTIVGYTRRDLSVWSEVMSRCLSAYGVTRNDTFSVSYGYGLFTGGLGAHYGVENLGATVIPAST
GNTEKHVRLIRDLGITGIACTPSYALYLAEVVERMGLTKNDINLRIGAFGAEPWTESMRKEIEERLGLKGYNIYGLSEIM
GPGVSYECQEQHGSHINEDHFYPEIINPETLERLPDGEVGELVFTTLTKEGMPLLRYRTKDLTSLMEGECPCGRTNIRMS
GIVGRSDDMLIIRGINVFPSQVESVILDMPQFEPQYMLVVDRKNNLDSLQVQVEVRKDFFSDDMGSMLAMKKALSDKLKS
VLSISAEVKLMEPNSIARSEGKSKRVIDNRILK

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=425, Percent_Identity=52.7058823529412, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48580; Mature: 48580

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWNKNKECMSRDEMSALQGKRLNKLVNLVYHNVPFYRNKMQEMDLSPDDIQTIEDIVKL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHC
PFTTKQDLRDNYPYGLQAAPASEIVRVHASSGTTGNPTIVGYTRRDLSVWSEVMSRCLSA
CCCCHHHHHCCCCCCCCCCCHHHEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
YGVTRNDTFSVSYGYGLFTGGLGAHYGVENLGATVIPASTGNTEKHVRLIRDLGITGIAC
CCCCCCCEEEEEECCHHEECCCCCCCCHHHCCCEEEECCCCCHHHHHHHHHHCCCCEEEE
TPSYALYLAEVVERMGLTKNDINLRIGAFGAEPWTESMRKEIEERLGLKGYNIYGLSEIM
CCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHH
GPGVSYECQEQHGSHINEDHFYPEIINPETLERLPDGEVGELVFTTLTKEGMPLLRYRTK
CCCCCEEEHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHH
DLTSLMEGECPCGRTNIRMSGIVGRSDDMLIIRGINVFPSQVESVILDMPQFEPQYMLVV
HHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEE
DRKNNLDSLQVQVEVRKDFFSDDMGSMLAMKKALSDKLKSVLSISAEVKLMEPNSIARSE
ECCCCCCEEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCC
GKSKRVIDNRILK
CCCHHHHHHHCCC
>Mature Secondary Structure
MIWNKNKECMSRDEMSALQGKRLNKLVNLVYHNVPFYRNKMQEMDLSPDDIQTIEDIVKL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHC
PFTTKQDLRDNYPYGLQAAPASEIVRVHASSGTTGNPTIVGYTRRDLSVWSEVMSRCLSA
CCCCHHHHHCCCCCCCCCCCHHHEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
YGVTRNDTFSVSYGYGLFTGGLGAHYGVENLGATVIPASTGNTEKHVRLIRDLGITGIAC
CCCCCCCEEEEEECCHHEECCCCCCCCHHHCCCEEEECCCCCHHHHHHHHHHCCCCEEEE
TPSYALYLAEVVERMGLTKNDINLRIGAFGAEPWTESMRKEIEERLGLKGYNIYGLSEIM
CCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHH
GPGVSYECQEQHGSHINEDHFYPEIINPETLERLPDGEVGELVFTTLTKEGMPLLRYRTK
CCCCCEEEHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHH
DLTSLMEGECPCGRTNIRMSGIVGRSDDMLIIRGINVFPSQVESVILDMPQFEPQYMLVV
HHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEE
DRKNNLDSLQVQVEVRKDFFSDDMGSMLAMKKALSDKLKSVLSISAEVKLMEPNSIARSE
ECCCCCCEEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCC
GKSKRVIDNRILK
CCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]