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The map label for this gene is pgk [H]

Identifier: 150004745

GI number: 150004745

Start: 2848730

End: 2849983

Strand: Direct

Name: pgk [H]

Synonym: BVU_2206

Alternate gene names: 150004745

Gene position: 2848730-2849983 (Clockwise)

Preceding gene: 150004738

Following gene: 150004749

Centisome position: 55.17

GC content: 42.26

Gene sequence:

>1254_bases
ATGATGACAATTGACAAATTCAACTTTGCCGGTAAAAAGGCAATTGTCCGTGTGGACTTCAATGTACCTTTGGACGAAAA
TGGTAAAATTACTGATGATACTCGTATCCGTGGTGCTCTTCCTACACTGAAAAAAGTGTTGGCTGATGGTGGCAGCTTGA
TTATCATGTCACACATGGGTAAACCCAAAGGTAAGGTAAATGCTAAATATTCATTGAGCCAGATTGTCGATGCTGTTTCT
GAAAAATTAGGTGTACCTGTTCAATTTGCTCCTGATTGTGCGAAAGCCGGTGATGCTGCAGCTGCTTTGAAACCGGGTGA
AGTCCTGTTGTTGGAAAATTTGCGTTTCTATCCTGAAGAAGAAGGAAAGCCTGTTGGCATTGACAAAGAAGATCCTGCAT
ACGAAGATGCCAAGAAAGCGATGAAGGCTTCTCAGAAAGAATTTGCCAAGACTTTGGCTTCTTATGCTGATTGCTATATC
AATGACGCATTCGGTACTGCTCACCGTAAACATGCTTCTACAGCCGTTATCGCTGACTATTTTGATGCGGACAACAAGAT
GTTGGGGTATTTGATGGAAAAAGAAGTTCAAGCTGTTGATAATATCCTGAAAGATATCAAGCGCCCGTTCACTGCTATTA
TGGGTGGTTCCAAGGTGTCTACTAAGATTGGTATCATTGAAAACCTGATGGATAAAGTGGATAACTTGATTCTTTGCGGT
GGTATGACTTATACTTTTGCAAAAGCTCAAGGTGGAAAAATTGGTAATTCTATCGTAGAAGATGACAAATTGGATTTGGC
TCTTGATATCATTGCTAAGGCTAAAGCTAAAGGTGTGAATTTGGTATTGGGCTCTGATTGTGTGGCTGCTGATGCATTCT
CTAACGATGCTCATACTCAGGTTGTTCCTGCAAATAATATTCCTGACGGATGGGAAGGTTTGGATGCAGGTCCTGAAACT
CAGAAAGCATTTGCTGCTGCTATTGAAGATGCCAAGACTATTCTGTGGAACGGTCCTGCCGGTGTTTTTGAATTCGATAA
CTTTACTGCCGGTTCACGTGCTATCGCTGAAGCTATCGCAAAAGCAACTAAGAACGGTGCATTCTCATTGATCGGTGGTG
GTGACTCTGTAGCTTGTATCAACAAGTTCGGCATGGCTGACCAGGTTTCTTATATCTCTACCGGTGGCGGTGCTTTGTTG
GAAGCAATTGAAGGAAAAATTCTTCCGGGTGTTGCAGCTATCAAAGGTGAATAA

Upstream 100 bases:

>100_bases
TTACCCCCCTGACACACTGCTAATAAAAAATATTAGTAACTTTGCAACACCCAAAATAAGCGAGATTGTATTTATACACT
ATAAACAAAAATAAGAGATT

Downstream 100 bases:

>100_bases
TTAATTTTCTGCTATATATAAAAAAGGCAGCCTTTTCGAAAGCTGCCTTTTTTATATTCTTTATTTTGTACTTTTCAGAA
CATGAACAAAACTGTTGCTA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MMTIDKFNFAGKKAIVRVDFNVPLDENGKITDDTRIRGALPTLKKVLADGGSLIIMSHMGKPKGKVNAKYSLSQIVDAVS
EKLGVPVQFAPDCAKAGDAAAALKPGEVLLLENLRFYPEEEGKPVGIDKEDPAYEDAKKAMKASQKEFAKTLASYADCYI
NDAFGTAHRKHASTAVIADYFDADNKMLGYLMEKEVQAVDNILKDIKRPFTAIMGGSKVSTKIGIIENLMDKVDNLILCG
GMTYTFAKAQGGKIGNSIVEDDKLDLALDIIAKAKAKGVNLVLGSDCVAADAFSNDAHTQVVPANNIPDGWEGLDAGPET
QKAFAAAIEDAKTILWNGPAGVFEFDNFTAGSRAIAEAIAKATKNGAFSLIGGGDSVACINKFGMADQVSYISTGGGALL
EAIEGKILPGVAAIKGE

Sequences:

>Translated_417_residues
MMTIDKFNFAGKKAIVRVDFNVPLDENGKITDDTRIRGALPTLKKVLADGGSLIIMSHMGKPKGKVNAKYSLSQIVDAVS
EKLGVPVQFAPDCAKAGDAAAALKPGEVLLLENLRFYPEEEGKPVGIDKEDPAYEDAKKAMKASQKEFAKTLASYADCYI
NDAFGTAHRKHASTAVIADYFDADNKMLGYLMEKEVQAVDNILKDIKRPFTAIMGGSKVSTKIGIIENLMDKVDNLILCG
GMTYTFAKAQGGKIGNSIVEDDKLDLALDIIAKAKAKGVNLVLGSDCVAADAFSNDAHTQVVPANNIPDGWEGLDAGPET
QKAFAAAIEDAKTILWNGPAGVFEFDNFTAGSRAIAEAIAKATKNGAFSLIGGGDSVACINKFGMADQVSYISTGGGALL
EAIEGKILPGVAAIKGE
>Mature_417_residues
MMTIDKFNFAGKKAIVRVDFNVPLDENGKITDDTRIRGALPTLKKVLADGGSLIIMSHMGKPKGKVNAKYSLSQIVDAVS
EKLGVPVQFAPDCAKAGDAAAALKPGEVLLLENLRFYPEEEGKPVGIDKEDPAYEDAKKAMKASQKEFAKTLASYADCYI
NDAFGTAHRKHASTAVIADYFDADNKMLGYLMEKEVQAVDNILKDIKRPFTAIMGGSKVSTKIGIIENLMDKVDNLILCG
GMTYTFAKAQGGKIGNSIVEDDKLDLALDIIAKAKAKGVNLVLGSDCVAADAFSNDAHTQVVPANNIPDGWEGLDAGPET
QKAFAAAIEDAKTILWNGPAGVFEFDNFTAGSRAIAEAIAKATKNGAFSLIGGGDSVACINKFGMADQVSYISTGGGALL
EAIEGKILPGVAAIKGE

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=419, Percent_Identity=43.1980906921241, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI31543397, Length=419, Percent_Identity=42.7207637231504, Blast_Score=324, Evalue=1e-88,
Organism=Escherichia coli, GI1789294, Length=416, Percent_Identity=38.7019230769231, Blast_Score=275, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17508823, Length=418, Percent_Identity=45.933014354067, Blast_Score=359, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6319857, Length=418, Percent_Identity=45.6937799043062, Blast_Score=349, Evalue=6e-97,
Organism=Drosophila melanogaster, GI17136394, Length=419, Percent_Identity=45.346062052506, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24581203, Length=422, Percent_Identity=42.4170616113744, Blast_Score=311, Evalue=6e-85,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 44033; Mature: 44033

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTIDKFNFAGKKAIVRVDFNVPLDENGKITDDTRIRGALPTLKKVLADGGSLIIMSHMG
CCEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
KPKGKVNAKYSLSQIVDAVSEKLGVPVQFAPDCAKAGDAAAALKPGEVLLLENLRFYPEE
CCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHCCCCCHHCCCCCCEEEEECCCCCCCC
EGKPVGIDKEDPAYEDAKKAMKASQKEFAKTLASYADCYINDAFGTAHRKHASTAVIADY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCEEEEHH
FDADNKMLGYLMEKEVQAVDNILKDIKRPFTAIMGGSKVSTKIGIIENLMDKVDNLILCG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEC
GMTYTFAKAQGGKIGNSIVEDDKLDLALDIIAKAKAKGVNLVLGSDCVAADAFSNDAHTQ
CCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCEE
VVPANNIPDGWEGLDAGPETQKAFAAAIEDAKTILWNGPAGVFEFDNFTAGSRAIAEAIA
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCEECCCCCCCHHHHHHHHH
KATKNGAFSLIGGGDSVACINKFGMADQVSYISTGGGALLEAIEGKILPGVAAIKGE
HHHCCCCEEEEECCCCEEHHHHCCCCHHHHEEECCCHHHHHHHCCCCCCCEEECCCC
>Mature Secondary Structure
MMTIDKFNFAGKKAIVRVDFNVPLDENGKITDDTRIRGALPTLKKVLADGGSLIIMSHMG
CCEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
KPKGKVNAKYSLSQIVDAVSEKLGVPVQFAPDCAKAGDAAAALKPGEVLLLENLRFYPEE
CCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHCCCCCHHCCCCCCEEEEECCCCCCCC
EGKPVGIDKEDPAYEDAKKAMKASQKEFAKTLASYADCYINDAFGTAHRKHASTAVIADY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCEEEEHH
FDADNKMLGYLMEKEVQAVDNILKDIKRPFTAIMGGSKVSTKIGIIENLMDKVDNLILCG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEC
GMTYTFAKAQGGKIGNSIVEDDKLDLALDIIAKAKAKGVNLVLGSDCVAADAFSNDAHTQ
CCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCEE
VVPANNIPDGWEGLDAGPETQKAFAAAIEDAKTILWNGPAGVFEFDNFTAGSRAIAEAIA
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCEECCCCCCCHHHHHHHHH
KATKNGAFSLIGGGDSVACINKFGMADQVSYISTGGGALLEAIEGKILPGVAAIKGE
HHHCCCCEEEEECCCCEEHHHHCCCCHHHHEEECCCHHHHHHHCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]