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The map label for this gene is uxuA [H]

Identifier: 150004712

GI number: 150004712

Start: 2808032

End: 2809219

Strand: Direct

Name: uxuA [H]

Synonym: BVU_2173

Alternate gene names: 150004712

Gene position: 2808032-2809219 (Clockwise)

Preceding gene: 150004711

Following gene: 150004713

Centisome position: 54.39

GC content: 48.91

Gene sequence:

>1188_bases
ATGGAAAAAACATGGAGATGGTTTGGCAAGAAAGATGAGATTACACTTACCATGTTGCGTCAGATAGGAGTAGAAGGGAT
TGTTACTGCTTTGCACGATGTACCTAACGGTGAAGTCTGGCCCTTGGAAACTGTCAAGGAAATGAAAGAGTATATAGAAT
CTGCCGGACTTCGCTGGTCGGTGGTGGAAAGTTTGCCTGTATGTGAGGCAATCAAGTATGCAGGCCCTGACAGAGACCGG
TTGATAACAAACTATATACAAAGCCTTACCAACCTCGGCAAGGCGGGCATCAAAACTGTGTGCTACAACTTTATGCCGGT
CATTGACTGGATTCGTACGGACTTGAACCATCCCTGGCCGGACGGCACCACATCACTTTATTTCAATAAAACACGTTTTG
CCTATTTCGACTTGAAAATCCTGAAAAGGAAACATGCGGAAAAGGATTATTCCGAAAAGGAACTGATGGAGGTGGAAAAA
TTAGGCAGCCGCATCACTGGGGAGGAAGAACTGGAGCTGATAGATACGGTCATTGTGAAGACACAAGGTTTTGTGAATGG
AAATATACGGGAAGGGGAGACTGAGCCCGTTTCGGTTTTCAGGAGGCTTCTATCCCTTTATGAAGGTGTGGACAAGGGCA
TGTTGCGCGAGAATATGCGTTATTTTCTTGCAGCCGTCATGCCGGTGTGTGAGAAATATGGCATTGACATGTGCGTGCAT
CCCGATGACCCACCCTTTCAGATGCTTGGACTTCCCCGTATCGTGACCTGTGAGGAGGATATTGCCTGGATTCTAGATGC
CGTGGACAATCCACACAATGGGCTGACATTCTGTGCCGGTTCACTCAGTGCCGGTGTACACAATGACACCCGTGGGCTGG
CACGCAGGTTTGCCGGTCGTACCCGCTTTGTCCATCTTCGCAGCACAGAGACTTTGTCCGGTGGGGATTTCATAGAGAGT
TCGCACCTGTCCGGCCGGGGACATCTGATAGAACTGATTCGTGTCTTCGAATCCTCAAATCCCGGCTTGCCCATGCGGGT
GGATCATGGCCGCATGATGCTTGGGGATGAGAAACTTGGATACAATCCGGGATATTCGTTTCATGGACGTATGCTGGCAT
TGGCGCAAGTGGAAGGGATGATGTCCGTTGTGCAGGATGAATTGCAGGAACAGCGAATGAGATTTTAA

Upstream 100 bases:

>100_bases
CCGGAAAAAGAAACTAAACAAACTTGTGATAAAGGCTCTTGATGAAGGTGTCATACTGGATCAAGTATCGGTTTATCCAC
TTTAATATTGCATAGAACGG

Downstream 100 bases:

>100_bases
ATAGTAATATGGATTATACCGATTAAATTATATGCCGATTGAAATGAATGAATTATTTGGAATTGCAGGAAAAGTAGCCG
TTATCACTGGAGCCGGTGGA

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MEKTWRWFGKKDEITLTMLRQIGVEGIVTALHDVPNGEVWPLETVKEMKEYIESAGLRWSVVESLPVCEAIKYAGPDRDR
LITNYIQSLTNLGKAGIKTVCYNFMPVIDWIRTDLNHPWPDGTTSLYFNKTRFAYFDLKILKRKHAEKDYSEKELMEVEK
LGSRITGEEELELIDTVIVKTQGFVNGNIREGETEPVSVFRRLLSLYEGVDKGMLRENMRYFLAAVMPVCEKYGIDMCVH
PDDPPFQMLGLPRIVTCEEDIAWILDAVDNPHNGLTFCAGSLSAGVHNDTRGLARRFAGRTRFVHLRSTETLSGGDFIES
SHLSGRGHLIELIRVFESSNPGLPMRVDHGRMMLGDEKLGYNPGYSFHGRMLALAQVEGMMSVVQDELQEQRMRF

Sequences:

>Translated_395_residues
MEKTWRWFGKKDEITLTMLRQIGVEGIVTALHDVPNGEVWPLETVKEMKEYIESAGLRWSVVESLPVCEAIKYAGPDRDR
LITNYIQSLTNLGKAGIKTVCYNFMPVIDWIRTDLNHPWPDGTTSLYFNKTRFAYFDLKILKRKHAEKDYSEKELMEVEK
LGSRITGEEELELIDTVIVKTQGFVNGNIREGETEPVSVFRRLLSLYEGVDKGMLRENMRYFLAAVMPVCEKYGIDMCVH
PDDPPFQMLGLPRIVTCEEDIAWILDAVDNPHNGLTFCAGSLSAGVHNDTRGLARRFAGRTRFVHLRSTETLSGGDFIES
SHLSGRGHLIELIRVFESSNPGLPMRVDHGRMMLGDEKLGYNPGYSFHGRMLALAQVEGMMSVVQDELQEQRMRF
>Mature_395_residues
MEKTWRWFGKKDEITLTMLRQIGVEGIVTALHDVPNGEVWPLETVKEMKEYIESAGLRWSVVESLPVCEAIKYAGPDRDR
LITNYIQSLTNLGKAGIKTVCYNFMPVIDWIRTDLNHPWPDGTTSLYFNKTRFAYFDLKILKRKHAEKDYSEKELMEVEK
LGSRITGEEELELIDTVIVKTQGFVNGNIREGETEPVSVFRRLLSLYEGVDKGMLRENMRYFLAAVMPVCEKYGIDMCVH
PDDPPFQMLGLPRIVTCEEDIAWILDAVDNPHNGLTFCAGSLSAGVHNDTRGLARRFAGRTRFVHLRSTETLSGGDFIES
SHLSGRGHLIELIRVFESSNPGLPMRVDHGRMMLGDEKLGYNPGYSFHGRMLALAQVEGMMSVVQDELQEQRMRF

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=395, Percent_Identity=43.7974683544304, Blast_Score=336, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 45017; Mature: 45017

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTWRWFGKKDEITLTMLRQIGVEGIVTALHDVPNGEVWPLETVKEMKEYIESAGLRWS
CCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VVESLPVCEAIKYAGPDRDRLITNYIQSLTNLGKAGIKTVCYNFMPVIDWIRTDLNHPWP
HHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGTTSLYFNKTRFAYFDLKILKRKHAEKDYSEKELMEVEKLGSRITGEEELELIDTVIVK
CCCCEEEEECCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TQGFVNGNIREGETEPVSVFRRLLSLYEGVDKGMLRENMRYFLAAVMPVCEKYGIDMCVH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PDDPPFQMLGLPRIVTCEEDIAWILDAVDNPHNGLTFCAGSLSAGVHNDTRGLARRFAGR
CCCCCHHHHCCCEEEECHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCC
TRFVHLRSTETLSGGDFIESSHLSGRGHLIELIRVFESSNPGLPMRVDHGRMMLGDEKLG
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCEEECCCCCC
YNPGYSFHGRMLALAQVEGMMSVVQDELQEQRMRF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKTWRWFGKKDEITLTMLRQIGVEGIVTALHDVPNGEVWPLETVKEMKEYIESAGLRWS
CCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VVESLPVCEAIKYAGPDRDRLITNYIQSLTNLGKAGIKTVCYNFMPVIDWIRTDLNHPWP
HHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGTTSLYFNKTRFAYFDLKILKRKHAEKDYSEKELMEVEKLGSRITGEEELELIDTVIVK
CCCCEEEEECCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TQGFVNGNIREGETEPVSVFRRLLSLYEGVDKGMLRENMRYFLAAVMPVCEKYGIDMCVH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PDDPPFQMLGLPRIVTCEEDIAWILDAVDNPHNGLTFCAGSLSAGVHNDTRGLARRFAGR
CCCCCHHHHCCCEEEECHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCC
TRFVHLRSTETLSGGDFIESSHLSGRGHLIELIRVFESSNPGLPMRVDHGRMMLGDEKLG
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCEEECCCCCC
YNPGYSFHGRMLALAQVEGMMSVVQDELQEQRMRF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA