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The map label for this gene is lacZ [H]

Identifier: 150004701

GI number: 150004701

Start: 2783698

End: 2786034

Strand: Direct

Name: lacZ [H]

Synonym: BVU_2162

Alternate gene names: 150004701

Gene position: 2783698-2786034 (Clockwise)

Preceding gene: 150004700

Following gene: 150004702

Centisome position: 53.91

GC content: 44.97

Gene sequence:

>2337_bases
ATGCAGAAACGTAATTTATTAATAATCATTTTATTCTTGTTTACCGGGACAATAGGATGGTCTGCCGAACGTATCTGGCA
GAATTTTGATTTCGATTGGCAGTTCCGTTTGGGAGAACAAGGTATCTATAAACCTGTCCAGCTTCCGCATGACTGGAGTA
TTGAACTGGACTTTAACGAAGAGGTGGGTCCTGAAAGTGGATATTTGCCGGGGGGTATAGGTTATTATAAGAAAGATTTC
AATGTGCCTGCGTCTTACAAAGGTAAGCGGGTCAGCATTGTGTTCGATGGCATCTATCATAAAGCTACCATCTATCTGAA
CGGACAGGAGGTAGATTACCATCGTTACGGATATACTTCATTTGAAACTGACTTGACTCCTTACTTGAAATATGGAGGAA
AGAATACATTGAGCGTGAAGGTAGATCATTCGGAGAAATCGCGCTGGTACACTGGCTCGGGTATTTATCGCCACGTATGG
ATGCAAGTAACCAATCCGATACATGTCAAGATGTGGGGTACATATATTACCACTCCCCGAGTGTCGGCAGAATCGGCCAT
CGTATCTTGTGTAACAACTGTAGCCAATACTTCGGCATTGACCGGTGAAATAGAAATTATGCAACGAATAGTGGATGCAC
AAGGCAATCTGTTGAAGATAAACGGCAAGCAGTATGCAGCCCGAACAGAGGTTGTGATGCCGGAAAACGGGACAAAAGAT
ATTGCACAGTCTTTCACGCTGTCCAACCCACAATTGTGGAATTTGGAAAAACCTTATCTTTATCGTTTGGAAACAATATT
GAAACAAAAGGGAAAGGTGATAGACCGTTACACGACCCGTTTCGGGGTGCGGACCATCGGTTTCGATAAGGACAAAGGCT
TCTTCTTGAACGGGAAGAATATCAAGATGAAAGGTGCGTGCCTGCATCAGGATGCTGGATGCTTGGGGGTTGCCGTTCCA
AACCGTTCATACGAACGCCGTCTGACTATCTTAAAGGAGTTTGGAGCAAATGCCATCCGCTGTTCACACAATCCGCCTTC
ACCGGAGTTCTTGAATTATTGTGATTCCATTGGTTTCTTAGTCGTTGACGAGGCTTTCGACAAGTGGAAGTCGGGATATT
ATGAGCAGTTCTTTGATGAATGTTGGCAACAAGATATTCGTGACATGATTGTGCGCGACCGTAACCATCCTTCCATCGTC
CTTTGGAGTATCGGCAATGAATTGGCAGAAGCCACCCGTAAGGACAACGTGGGTGTGGAACGTGCCACCTTGTTGCGTGA
CTTCGTACATAAATTAGAACCGACACGTCCAACCATGTTGGCACTGGCACCGGCATACCAAGATAAGTTTGCTTCAGTAA
CTGATGTGGTAGGGTATAATTATAGCGAACTATCTTATATAGAGGACAAGAAAAAGCATCCTGAACGAATCGGCCTGATA
AGTGAAAGTTATCCCTATTATAGCGGATTGAGACCTTATGAGGCAAGGGATTACTCTCCCAAGAATCCGTGGAATTATGT
GATGGAAAATGATTACTTTTGTGGATCGTTTGTTTGGGCCGGAGTCGATTATATCGGAGAAAGCATGGGTTGGCCGAGTA
AGGGATGGGCTGCTACGCTTTTCGATATGTGCATGGACGAGAAGCCTCGTGCCGCCTATTTCCGTGCGATGTGGACAGAC
AAGCCTGTCTTGAAAATGGCTGTCGTGGACTATAGCATAGATGAAGATCCGGGTAAGGACCACTGGCAGACACCGCCTAT
GGTGCATGACTGGACTTTTCCATATACCGATTCACGTGTGTTGCCAATTCATACCCCATCTAATTGTGACGAAGTGGTAC
TGATAGATCCACGTGGAAAGAAATATGGACCGCGCAAACCGAAAGACTATCTGAATAATACCATTATTTGGAATCAGCCT
TATCGACCTGGGAAGGTGGTTGCTATCGGATACAAGGATGGTAAAGAGGTGTGCCGCGACAGCATTCAGACAAGTAAAAT
TAAAGCAGCATGTTTCACACTTACACCTGACAAAACCGTATTGCAAGCAGACGGACAAGACCTTGCTTTCATTGCTTTAC
AATTATTTGATGAAAATGGGGTGCCTGTAAGGATAAACGACCGTGTGGTAAATGCAACAGTGGAAGGCACTGGAAAATTG
CTGGGGATAGATAGTGGAGAAATGCGTCGAGCATATCGTTTCAACAGCCATGAGCTTCCTACTTATCAGGGCAGGTGCAT
GCTGGTGATACAGGCTGGACGAAGTAAGGGGATGATGAGCGTAAAGGTTTGCGTAGAAGGCCTTCCTGAACAAACAATAA
CGATAAAAGTACACTAA

Upstream 100 bases:

>100_bases
TTATCGTCCTAATAGGGTTGTTGTGCCAGCTCCTGCAGGAAATATCGATGAAATACAGATACTATGAAAGAGTTGAAACA
TATCATAATATTAATCACTT

Downstream 100 bases:

>100_bases
TTTTTATAATAGCAGTAAGAATGACAACATTAAAAGATTTATTTGCTGGTTTGCTTCTTGTTATCTTCTTTCCCATTAGC
TCATGGGCTGAAGGGGTGAA

Product: beta-glycosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MQKRNLLIIILFLFTGTIGWSAERIWQNFDFDWQFRLGEQGIYKPVQLPHDWSIELDFNEEVGPESGYLPGGIGYYKKDF
NVPASYKGKRVSIVFDGIYHKATIYLNGQEVDYHRYGYTSFETDLTPYLKYGGKNTLSVKVDHSEKSRWYTGSGIYRHVW
MQVTNPIHVKMWGTYITTPRVSAESAIVSCVTTVANTSALTGEIEIMQRIVDAQGNLLKINGKQYAARTEVVMPENGTKD
IAQSFTLSNPQLWNLEKPYLYRLETILKQKGKVIDRYTTRFGVRTIGFDKDKGFFLNGKNIKMKGACLHQDAGCLGVAVP
NRSYERRLTILKEFGANAIRCSHNPPSPEFLNYCDSIGFLVVDEAFDKWKSGYYEQFFDECWQQDIRDMIVRDRNHPSIV
LWSIGNELAEATRKDNVGVERATLLRDFVHKLEPTRPTMLALAPAYQDKFASVTDVVGYNYSELSYIEDKKKHPERIGLI
SESYPYYSGLRPYEARDYSPKNPWNYVMENDYFCGSFVWAGVDYIGESMGWPSKGWAATLFDMCMDEKPRAAYFRAMWTD
KPVLKMAVVDYSIDEDPGKDHWQTPPMVHDWTFPYTDSRVLPIHTPSNCDEVVLIDPRGKKYGPRKPKDYLNNTIIWNQP
YRPGKVVAIGYKDGKEVCRDSIQTSKIKAACFTLTPDKTVLQADGQDLAFIALQLFDENGVPVRINDRVVNATVEGTGKL
LGIDSGEMRRAYRFNSHELPTYQGRCMLVIQAGRSKGMMSVKVCVEGLPEQTITIKVH

Sequences:

>Translated_778_residues
MQKRNLLIIILFLFTGTIGWSAERIWQNFDFDWQFRLGEQGIYKPVQLPHDWSIELDFNEEVGPESGYLPGGIGYYKKDF
NVPASYKGKRVSIVFDGIYHKATIYLNGQEVDYHRYGYTSFETDLTPYLKYGGKNTLSVKVDHSEKSRWYTGSGIYRHVW
MQVTNPIHVKMWGTYITTPRVSAESAIVSCVTTVANTSALTGEIEIMQRIVDAQGNLLKINGKQYAARTEVVMPENGTKD
IAQSFTLSNPQLWNLEKPYLYRLETILKQKGKVIDRYTTRFGVRTIGFDKDKGFFLNGKNIKMKGACLHQDAGCLGVAVP
NRSYERRLTILKEFGANAIRCSHNPPSPEFLNYCDSIGFLVVDEAFDKWKSGYYEQFFDECWQQDIRDMIVRDRNHPSIV
LWSIGNELAEATRKDNVGVERATLLRDFVHKLEPTRPTMLALAPAYQDKFASVTDVVGYNYSELSYIEDKKKHPERIGLI
SESYPYYSGLRPYEARDYSPKNPWNYVMENDYFCGSFVWAGVDYIGESMGWPSKGWAATLFDMCMDEKPRAAYFRAMWTD
KPVLKMAVVDYSIDEDPGKDHWQTPPMVHDWTFPYTDSRVLPIHTPSNCDEVVLIDPRGKKYGPRKPKDYLNNTIIWNQP
YRPGKVVAIGYKDGKEVCRDSIQTSKIKAACFTLTPDKTVLQADGQDLAFIALQLFDENGVPVRINDRVVNATVEGTGKL
LGIDSGEMRRAYRFNSHELPTYQGRCMLVIQAGRSKGMMSVKVCVEGLPEQTITIKVH
>Mature_778_residues
MQKRNLLIIILFLFTGTIGWSAERIWQNFDFDWQFRLGEQGIYKPVQLPHDWSIELDFNEEVGPESGYLPGGIGYYKKDF
NVPASYKGKRVSIVFDGIYHKATIYLNGQEVDYHRYGYTSFETDLTPYLKYGGKNTLSVKVDHSEKSRWYTGSGIYRHVW
MQVTNPIHVKMWGTYITTPRVSAESAIVSCVTTVANTSALTGEIEIMQRIVDAQGNLLKINGKQYAARTEVVMPENGTKD
IAQSFTLSNPQLWNLEKPYLYRLETILKQKGKVIDRYTTRFGVRTIGFDKDKGFFLNGKNIKMKGACLHQDAGCLGVAVP
NRSYERRLTILKEFGANAIRCSHNPPSPEFLNYCDSIGFLVVDEAFDKWKSGYYEQFFDECWQQDIRDMIVRDRNHPSIV
LWSIGNELAEATRKDNVGVERATLLRDFVHKLEPTRPTMLALAPAYQDKFASVTDVVGYNYSELSYIEDKKKHPERIGLI
SESYPYYSGLRPYEARDYSPKNPWNYVMENDYFCGSFVWAGVDYIGESMGWPSKGWAATLFDMCMDEKPRAAYFRAMWTD
KPVLKMAVVDYSIDEDPGKDHWQTPPMVHDWTFPYTDSRVLPIHTPSNCDEVVLIDPRGKKYGPRKPKDYLNNTIIWNQP
YRPGKVVAIGYKDGKEVCRDSIQTSKIKAACFTLTPDKTVLQADGQDLAFIALQLFDENGVPVRINDRVVNATVEGTGKL
LGIDSGEMRRAYRFNSHELPTYQGRCMLVIQAGRSKGMMSVKVCVEGLPEQTITIKVH

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=419, Percent_Identity=25.5369928400955, Blast_Score=109, Evalue=1e-23,
Organism=Escherichia coli, GI1787903, Length=449, Percent_Identity=27.6169265033408, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI48994920, Length=506, Percent_Identity=24.5059288537549, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI1786539, Length=381, Percent_Identity=25.9842519685039, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17510825, Length=425, Percent_Identity=26.1176470588235, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI19922582, Length=428, Percent_Identity=27.3364485981308, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI62471735, Length=428, Percent_Identity=27.3364485981308, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24655438, Length=428, Percent_Identity=27.3364485981308, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24651745, Length=414, Percent_Identity=27.0531400966184, Blast_Score=127, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 88985; Mature: 88985

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRNLLIIILFLFTGTIGWSAERIWQNFDFDWQFRLGEQGIYKPVQLPHDWSIELDFNE
CCCCCEEEEEEEHHHCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCC
EVGPESGYLPGGIGYYKKDFNVPASYKGKRVSIVFDGIYHKATIYLNGQEVDYHRYGYTS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEEEECCCEEEEEECCCCC
FETDLTPYLKYGGKNTLSVKVDHSEKSRWYTGSGIYRHVWMQVTNPIHVKMWGTYITTPR
CCCCCCHHHHCCCCEEEEEEEECCCCCCEEECCCCEEEEEEEECCCEEEEEEEEEECCCC
VSAESAIVSCVTTVANTSALTGEIEIMQRIVDAQGNLLKINGKQYAARTEVVMPENGTKD
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEEEECCCCCCHH
IAQSFTLSNPQLWNLEKPYLYRLETILKQKGKVIDRYTTRFGVRTIGFDKDKGFFLNGKN
HHHHHCCCCCCEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCEEEECCCCCCCEEEECCC
IKMKGACLHQDAGCLGVAVPNRSYERRLTILKEFGANAIRCSHNPPSPEFLNYCDSIGFL
EEEECEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCEE
VVDEAFDKWKSGYYEQFFDECWQQDIRDMIVRDRNHPSIVLWSIGNELAEATRKDNVGVE
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCHH
RATLLRDFVHKLEPTRPTMLALAPAYQDKFASVTDVVGYNYSELSYIEDKKKHPERIGLI
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCEE
SESYPYYSGLRPYEARDYSPKNPWNYVMENDYFCGSFVWAGVDYIGESMGWPSKGWAATL
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHH
FDMCMDEKPRAAYFRAMWTDKPVLKMAVVDYSIDEDPGKDHWQTPPMVHDWTFPYTDSRV
HHHHHCCCCCHHHEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCEE
LPIHTPSNCDEVVLIDPRGKKYGPRKPKDYLNNTIIWNQPYRPGKVVAIGYKDGKEVCRD
EEEECCCCCCEEEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCEEEEEECCCCHHHHHH
SIQTSKIKAACFTLTPDKTVLQADGQDLAFIALQLFDENGVPVRINDRVVNATVEGTGKL
HHHHCEEEEEEEEECCCCEEEECCCCCEEEEEEEEECCCCCEEEECCEEEEEEEECCCEE
LGIDSGEMRRAYRFNSHELPTYQGRCMLVIQAGRSKGMMSVKVCVEGLPEQTITIKVH
EECCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEHHCCCCCCEEEEEEC
>Mature Secondary Structure
MQKRNLLIIILFLFTGTIGWSAERIWQNFDFDWQFRLGEQGIYKPVQLPHDWSIELDFNE
CCCCCEEEEEEEHHHCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCC
EVGPESGYLPGGIGYYKKDFNVPASYKGKRVSIVFDGIYHKATIYLNGQEVDYHRYGYTS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEEEECCCEEEEEECCCCC
FETDLTPYLKYGGKNTLSVKVDHSEKSRWYTGSGIYRHVWMQVTNPIHVKMWGTYITTPR
CCCCCCHHHHCCCCEEEEEEEECCCCCCEEECCCCEEEEEEEECCCEEEEEEEEEECCCC
VSAESAIVSCVTTVANTSALTGEIEIMQRIVDAQGNLLKINGKQYAARTEVVMPENGTKD
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEEEECCCCCCHH
IAQSFTLSNPQLWNLEKPYLYRLETILKQKGKVIDRYTTRFGVRTIGFDKDKGFFLNGKN
HHHHHCCCCCCEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCEEEECCCCCCCEEEECCC
IKMKGACLHQDAGCLGVAVPNRSYERRLTILKEFGANAIRCSHNPPSPEFLNYCDSIGFL
EEEECEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCEE
VVDEAFDKWKSGYYEQFFDECWQQDIRDMIVRDRNHPSIVLWSIGNELAEATRKDNVGVE
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCHH
RATLLRDFVHKLEPTRPTMLALAPAYQDKFASVTDVVGYNYSELSYIEDKKKHPERIGLI
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCCEE
SESYPYYSGLRPYEARDYSPKNPWNYVMENDYFCGSFVWAGVDYIGESMGWPSKGWAATL
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHH
FDMCMDEKPRAAYFRAMWTDKPVLKMAVVDYSIDEDPGKDHWQTPPMVHDWTFPYTDSRV
HHHHHCCCCCHHHEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCEE
LPIHTPSNCDEVVLIDPRGKKYGPRKPKDYLNNTIIWNQPYRPGKVVAIGYKDGKEVCRD
EEEECCCCCCEEEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCEEEEEECCCCHHHHHH
SIQTSKIKAACFTLTPDKTVLQADGQDLAFIALQLFDENGVPVRINDRVVNATVEGTGKL
HHHHCEEEEEEEEECCCCEEEECCCCCEEEEEEEEECCCCCEEEECCEEEEEEEECCCEE
LGIDSGEMRRAYRFNSHELPTYQGRCMLVIQAGRSKGMMSVKVCVEGLPEQTITIKVH
EECCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA