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The map label for this gene is luxQ [H]

Identifier: 150004629

GI number: 150004629

Start: 2700262

End: 2704221

Strand: Direct

Name: luxQ [H]

Synonym: BVU_2089

Alternate gene names: 150004629

Gene position: 2700262-2704221 (Clockwise)

Preceding gene: 150004624

Following gene: 150004630

Centisome position: 52.3

GC content: 38.94

Gene sequence:

>3960_bases
ATGGGAATAAGAAAAAAATGTTTGATCATTACATTATTATGCTTTTCTAGTCTGATGCATGCAAGTGAATTCATGTTTAA
ACATTTGGAGGTGAAAGATGGTCTGTCAAACAATCAAGTCCTTGATATATTTAAAGATTCCGAAGGTTTTATGTGGTTTG
CCACAGCTTCCGGTTTAAATCGGTATGACGGGTGCCAGATGACTTTGTTTCGTAGTAATAATGCTGATCCGGCTTCTTTA
CCTGATAATTATATCAAAAGCATACAAGAAGATTATAAAGGAAATTTATGGATTCTTACCGGTGTGGGTTATGTCATTTA
CAACTCGGAATCAGAAACATTTGATAGGGAGGTGCATGCATGGCTATGTGAAGTCGGTATTGACGGAACTCCAGCATTAG
TATATATAGACCATAATAAAAATATGTGGTTTTATATAAAAGGAAAAGGCTGTTATTTGTACATTCCGGAATCTCAATTA
CTGTATCCGCTTTTGTTTGATACTCATCAGTTGCCAGAAGGTGATATTACGGACATTGTAGAATGTAGCAAGGGAATCTT
GTTGGTATATAATACCGGAAGACTTGTTTGTTTGGATACTCGGACAAATGAGATTAAATGGCAGCAGGATGATTTGGTTG
GGGAATTGGGAACTGACAAGCAGGGAATTTTCACTCTGTTTGTAGATCGTGATAATGATATATGGATGTACAGTCCGCTT
GGAATATGGGTTTATAATCCGGAACAGGAAAAGTGGCTGTCTTGGCTGACAAATATTATCAAGCGTCGGTCTCATAACAT
GGTCCGTGCTGTATCACAGGATAAGCAGGGGCGTATATGGATAGGAACAGATCAGGATGGCATTGATATATTGGATAAGA
AGACAGGGGAAGTGAGGCAGTTGCGGAACAAGACAGGTGATGAACGTAGTTTGCAAAATAATACAGTAATGGTTCTATAC
GAGGATTCCAGTGAAACTATGTGGGTGGGGACTTATAAAAAAGGAATTTCCTATTTTAATGAGTGTGCTTTTAAATTTGG
TGCAGAGTATATAGGAGATATTAGTTGCATTGAAGAAGACAAAGAGGGGTATGTGTGGCTGGGTACCAACGATGTCGGTA
TCATATATTGGAATTCCGTGACTGGCAACCGGGCTGCTTTTCCACAGAAAGGTATGGATAAACTCACTACTGATGCTATT
GTTTGCATTTTGAAAGCCGGTGATGGGAAACTTTGGATTGGTACTTTTGGGGGAGGCTTGATTTGTTATGATAACGGTCG
TATTATTCATTATAAAAAAAACATACCGGAACGGCAAAATTCTTTGGCTCATAATAATGTATTGGCTTTGGCTGAAGATA
AGCAGGGGATTATATGGATAGGTACATTGGGTGGGGGAGTGCAGAGTTTGAATCCCAAGACGGGTTTGTTCACCACTTAT
AATACAACTTCGGCCGGCTTGATATCCGATTATGTTTCCTCTTTGTGTATGGGAAAAGAGGGCTCTTTGTGGATTGGTAC
CGCTCAGGGACTTTCGGAATTGGATATTGAAACTAAAAAAGTGGTTAATCTGGAAGGTACTAAATCTGGTAAGGAATATT
TTTCTGATCAGAATATAAGTCAGGTGTATGAGGATAGCCGTGGATTGATATGGATTGGTACATGTGAGGGGCTGAATGTT
TATAATCCCAAAACGGATGAACTGATTATATTAGGAGTGGAGCAAGGAGTTTCCAGCCCTATCATTTCTGGAATAGTAGA
AGATGGTAATGAAAATATATGGGTGACTACAGCACGTGGAATAACTAATGTCATACCGGCAGTAGATTTAAAAACAGGGC
GCTATATTTTTCATAGTTGTGTTTATGATGACAAAGATGGTTTGCAAAATAGTGGGTTCAACCTGCGTTCCATTAAAAAA
TTGTCTTCTGGAGAAATTCTTATGGGAGGGCTGTATGGTATTAACCGCTTCCGTCCGGATGATATAAAATACAATAAAAA
ACGTCCCAGCGTGATGTTTACCCGTTTGTTCTTGTTCAATGAAGAAGTAGGGGTGGGTGAGGAATATGAAGGTAGGGTGA
TTTTGGATAAGGCGTTGAACAAGGTAGATCAGATAAAATTGAGTTATGAACAGAATATGTTCAGTGTACAATTTGCTTCT
GATAACTATATTTTGCCGGAAAAAACGGAGTATGCTTATAAACTGGAAGGTTTCAATGAGGGTTGGATGACTACTGCCTT
TGGCAAAGTGACTTATACTAATCTAGCTCCCGGAACTTATATGCTGAAGGTGAAAGCAGTCAACAGTGACGGATATGGTG
GAGATGAAGAAGCTTCATTGAAAATTGTTATCTATCCTCCTTTTTGGCGTTCCGTTTGGGCATATGTTGTTTATAGCCTT
TTGTTGGTTGCTGTATTGATATTGGGACGCTATTGGATTCTGCGTGGAGAACGGGATAAATTTAAAAAACAGCAAATAAA
GCAAGAAATAGAGAGGAATCAGGAGAAGGCAGATATGAAATTGAAGTTCTTCACTCATGTCGGCCACGAATTACGTACTC
CGCTCACTCTTATTATCTCACCGTTGGAAACGCTGATGAAGGAATATCAATCGGATGCTGCTCTGATGGATAAATTGAAT
ATAGTGCAACGCAATGCATTAAGGTTGTTGAATCTTGTAAATCAGTTGTTGGATTTTAGGAAAATTGATGTGAATGGATA
TTATTTAAGTCTGTCTGATGATGATATCATCTCTTGTATTCATACGATTTGTGATTCTTTTATCTCTTTGTCTGAAAAGA
AAGATATTTCTCTCATTTTTCATTCAGCAGTTCCTTCGTTGAATATGTTGTTTGATGGGGATAAAATGAGGGAAGTGATG
ATGAATCTGCTTTCCAATGCTTTAAAATTTACTTGCAATGGTGGACGAGTTGATGTGTCTGTCGGTTTAGTAGAAGGACA
GGATTCTCGGGAAATGCTGGAAATCAGAGTGGTTGATACAGGTGTCGGCATTAAAGAAGAAAACAGAGAACGCATTTTCG
AACGTTTTTATCAAGTGGATAATCCGGATATGAATATCTCAGATGGCGGAGGTGGTCTGAGTATTGTACGTGATTTTGTC
ACACTTCACGATGGCACGGTGAACGTAATGGATAATACTCCTGTCGGTTGTGTTTTTGTTATCCATATCCCGGTAAAGCG
TTCCGAGAGTAAACCGACGAAGATAGAACAGGTGCAAGTTACAGATAAGCCGGTAGAAGACATTTCCACACTTCAGATTC
CGGAGTTTTATATGGCGTCTAATGCCGGGGAGGAATCGGAAGAAGAACCAAACCATATAATAACAATAGAAGGACTGGAG
GAGGATATCCGAAGATTAGAATCTGGTAATACGGAAGAAATTGCAGAAGAAAAAAACATAGAAACAATCTCAGCCGTTGC
TCCACAAAGAGCAACGGTGATTCAATTGATTGAGGGTGAGGATAATGAGATGATAACTCATATTATTCCACCGGAGGAGT
TGCCGGAAATGGTGACTGCTGTTCCTGAAGAAAAAAGTGAACAGAAGTTGAAAACGGTTTGGAATCATGCTTATATTGAT
TTCAAACCTAGTGGGACTGCTATAACTTCGATGGATGAAAAACTGATAAATCATGCTGTGAAATATGTAGAAGACAATAT
TGCACGCAGTGATTTGTCTGTAGAAGAGTTAAGCAAGGAATTAGGGATGAGCCGCGTTCATTTATATAAAAAGTTATTGG
CTATTACCGGTAAGACTCCTATCGAGTTTATTCGTATAATTCGTTTACAGCGGGCTGCCCAATTACTCCGTGGAAGTCAA
CAGAATATTTCGGAAATAGCCTATCAGGTGGGCTTTAATAATCCGAAATATTTCAGTCGGTATTTTAAGGAAGAATTTGG
TATACTACCTTCGGCTTTTCAATATAGACAAGGCAGATAG

Upstream 100 bases:

>100_bases
TTGTGGGTATCGAATGATAAAAAAGCCGATATTAGTTTGTCTGTTATCAAGCTTTTTGCTTCATTTGCAGTGGAATAAAA
ATAATTAGCCTTTAAAATCT

Downstream 100 bases:

>100_bases
TTCTCAATATTTTATAGTGTCATTTAAAGTGTGTATCGGAGTTTCGTCAACAGACATACGTTCTGTAACAGATTTCATCT
ATGAGTAAAAACAATTCCAT

Product: two-component system sensor histidine kinase/response regulator, hybrid

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1319; Mature: 1318

Protein sequence:

>1319_residues
MGIRKKCLIITLLCFSSLMHASEFMFKHLEVKDGLSNNQVLDIFKDSEGFMWFATASGLNRYDGCQMTLFRSNNADPASL
PDNYIKSIQEDYKGNLWILTGVGYVIYNSESETFDREVHAWLCEVGIDGTPALVYIDHNKNMWFYIKGKGCYLYIPESQL
LYPLLFDTHQLPEGDITDIVECSKGILLVYNTGRLVCLDTRTNEIKWQQDDLVGELGTDKQGIFTLFVDRDNDIWMYSPL
GIWVYNPEQEKWLSWLTNIIKRRSHNMVRAVSQDKQGRIWIGTDQDGIDILDKKTGEVRQLRNKTGDERSLQNNTVMVLY
EDSSETMWVGTYKKGISYFNECAFKFGAEYIGDISCIEEDKEGYVWLGTNDVGIIYWNSVTGNRAAFPQKGMDKLTTDAI
VCILKAGDGKLWIGTFGGGLICYDNGRIIHYKKNIPERQNSLAHNNVLALAEDKQGIIWIGTLGGGVQSLNPKTGLFTTY
NTTSAGLISDYVSSLCMGKEGSLWIGTAQGLSELDIETKKVVNLEGTKSGKEYFSDQNISQVYEDSRGLIWIGTCEGLNV
YNPKTDELIILGVEQGVSSPIISGIVEDGNENIWVTTARGITNVIPAVDLKTGRYIFHSCVYDDKDGLQNSGFNLRSIKK
LSSGEILMGGLYGINRFRPDDIKYNKKRPSVMFTRLFLFNEEVGVGEEYEGRVILDKALNKVDQIKLSYEQNMFSVQFAS
DNYILPEKTEYAYKLEGFNEGWMTTAFGKVTYTNLAPGTYMLKVKAVNSDGYGGDEEASLKIVIYPPFWRSVWAYVVYSL
LLVAVLILGRYWILRGERDKFKKQQIKQEIERNQEKADMKLKFFTHVGHELRTPLTLIISPLETLMKEYQSDAALMDKLN
IVQRNALRLLNLVNQLLDFRKIDVNGYYLSLSDDDIISCIHTICDSFISLSEKKDISLIFHSAVPSLNMLFDGDKMREVM
MNLLSNALKFTCNGGRVDVSVGLVEGQDSREMLEIRVVDTGVGIKEENRERIFERFYQVDNPDMNISDGGGGLSIVRDFV
TLHDGTVNVMDNTPVGCVFVIHIPVKRSESKPTKIEQVQVTDKPVEDISTLQIPEFYMASNAGEESEEEPNHIITIEGLE
EDIRRLESGNTEEIAEEKNIETISAVAPQRATVIQLIEGEDNEMITHIIPPEELPEMVTAVPEEKSEQKLKTVWNHAYID
FKPSGTAITSMDEKLINHAVKYVEDNIARSDLSVEELSKELGMSRVHLYKKLLAITGKTPIEFIRIIRLQRAAQLLRGSQ
QNISEIAYQVGFNNPKYFSRYFKEEFGILPSAFQYRQGR

Sequences:

>Translated_1319_residues
MGIRKKCLIITLLCFSSLMHASEFMFKHLEVKDGLSNNQVLDIFKDSEGFMWFATASGLNRYDGCQMTLFRSNNADPASL
PDNYIKSIQEDYKGNLWILTGVGYVIYNSESETFDREVHAWLCEVGIDGTPALVYIDHNKNMWFYIKGKGCYLYIPESQL
LYPLLFDTHQLPEGDITDIVECSKGILLVYNTGRLVCLDTRTNEIKWQQDDLVGELGTDKQGIFTLFVDRDNDIWMYSPL
GIWVYNPEQEKWLSWLTNIIKRRSHNMVRAVSQDKQGRIWIGTDQDGIDILDKKTGEVRQLRNKTGDERSLQNNTVMVLY
EDSSETMWVGTYKKGISYFNECAFKFGAEYIGDISCIEEDKEGYVWLGTNDVGIIYWNSVTGNRAAFPQKGMDKLTTDAI
VCILKAGDGKLWIGTFGGGLICYDNGRIIHYKKNIPERQNSLAHNNVLALAEDKQGIIWIGTLGGGVQSLNPKTGLFTTY
NTTSAGLISDYVSSLCMGKEGSLWIGTAQGLSELDIETKKVVNLEGTKSGKEYFSDQNISQVYEDSRGLIWIGTCEGLNV
YNPKTDELIILGVEQGVSSPIISGIVEDGNENIWVTTARGITNVIPAVDLKTGRYIFHSCVYDDKDGLQNSGFNLRSIKK
LSSGEILMGGLYGINRFRPDDIKYNKKRPSVMFTRLFLFNEEVGVGEEYEGRVILDKALNKVDQIKLSYEQNMFSVQFAS
DNYILPEKTEYAYKLEGFNEGWMTTAFGKVTYTNLAPGTYMLKVKAVNSDGYGGDEEASLKIVIYPPFWRSVWAYVVYSL
LLVAVLILGRYWILRGERDKFKKQQIKQEIERNQEKADMKLKFFTHVGHELRTPLTLIISPLETLMKEYQSDAALMDKLN
IVQRNALRLLNLVNQLLDFRKIDVNGYYLSLSDDDIISCIHTICDSFISLSEKKDISLIFHSAVPSLNMLFDGDKMREVM
MNLLSNALKFTCNGGRVDVSVGLVEGQDSREMLEIRVVDTGVGIKEENRERIFERFYQVDNPDMNISDGGGGLSIVRDFV
TLHDGTVNVMDNTPVGCVFVIHIPVKRSESKPTKIEQVQVTDKPVEDISTLQIPEFYMASNAGEESEEEPNHIITIEGLE
EDIRRLESGNTEEIAEEKNIETISAVAPQRATVIQLIEGEDNEMITHIIPPEELPEMVTAVPEEKSEQKLKTVWNHAYID
FKPSGTAITSMDEKLINHAVKYVEDNIARSDLSVEELSKELGMSRVHLYKKLLAITGKTPIEFIRIIRLQRAAQLLRGSQ
QNISEIAYQVGFNNPKYFSRYFKEEFGILPSAFQYRQGR
>Mature_1318_residues
GIRKKCLIITLLCFSSLMHASEFMFKHLEVKDGLSNNQVLDIFKDSEGFMWFATASGLNRYDGCQMTLFRSNNADPASLP
DNYIKSIQEDYKGNLWILTGVGYVIYNSESETFDREVHAWLCEVGIDGTPALVYIDHNKNMWFYIKGKGCYLYIPESQLL
YPLLFDTHQLPEGDITDIVECSKGILLVYNTGRLVCLDTRTNEIKWQQDDLVGELGTDKQGIFTLFVDRDNDIWMYSPLG
IWVYNPEQEKWLSWLTNIIKRRSHNMVRAVSQDKQGRIWIGTDQDGIDILDKKTGEVRQLRNKTGDERSLQNNTVMVLYE
DSSETMWVGTYKKGISYFNECAFKFGAEYIGDISCIEEDKEGYVWLGTNDVGIIYWNSVTGNRAAFPQKGMDKLTTDAIV
CILKAGDGKLWIGTFGGGLICYDNGRIIHYKKNIPERQNSLAHNNVLALAEDKQGIIWIGTLGGGVQSLNPKTGLFTTYN
TTSAGLISDYVSSLCMGKEGSLWIGTAQGLSELDIETKKVVNLEGTKSGKEYFSDQNISQVYEDSRGLIWIGTCEGLNVY
NPKTDELIILGVEQGVSSPIISGIVEDGNENIWVTTARGITNVIPAVDLKTGRYIFHSCVYDDKDGLQNSGFNLRSIKKL
SSGEILMGGLYGINRFRPDDIKYNKKRPSVMFTRLFLFNEEVGVGEEYEGRVILDKALNKVDQIKLSYEQNMFSVQFASD
NYILPEKTEYAYKLEGFNEGWMTTAFGKVTYTNLAPGTYMLKVKAVNSDGYGGDEEASLKIVIYPPFWRSVWAYVVYSLL
LVAVLILGRYWILRGERDKFKKQQIKQEIERNQEKADMKLKFFTHVGHELRTPLTLIISPLETLMKEYQSDAALMDKLNI
VQRNALRLLNLVNQLLDFRKIDVNGYYLSLSDDDIISCIHTICDSFISLSEKKDISLIFHSAVPSLNMLFDGDKMREVMM
NLLSNALKFTCNGGRVDVSVGLVEGQDSREMLEIRVVDTGVGIKEENRERIFERFYQVDNPDMNISDGGGGLSIVRDFVT
LHDGTVNVMDNTPVGCVFVIHIPVKRSESKPTKIEQVQVTDKPVEDISTLQIPEFYMASNAGEESEEEPNHIITIEGLEE
DIRRLESGNTEEIAEEKNIETISAVAPQRATVIQLIEGEDNEMITHIIPPEELPEMVTAVPEEKSEQKLKTVWNHAYIDF
KPSGTAITSMDEKLINHAVKYVEDNIARSDLSVEELSKELGMSRVHLYKKLLAITGKTPIEFIRIIRLQRAAQLLRGSQQ
NISEIAYQVGFNNPKYFSRYFKEEFGILPSAFQYRQGR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=7e-25,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=29.0196078431373, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=30.2788844621514, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=29.4605809128631, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=29.4605809128631, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=24.8979591836735, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=27.3076923076923, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=25.8964143426295, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=279, Percent_Identity=22.9390681003584, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=211, Percent_Identity=27.0142180094787, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=26.8774703557312, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=221, Percent_Identity=30.316742081448, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=25.6302521008403, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 149441; Mature: 149310

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRKKCLIITLLCFSSLMHASEFMFKHLEVKDGLSNNQVLDIFKDSEGFMWFATASGLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCC
RYDGCQMTLFRSNNADPASLPDNYIKSIQEDYKGNLWILTGVGYVIYNSESETFDREVHA
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHH
WLCEVGIDGTPALVYIDHNKNMWFYIKGKGCYLYIPESQLLYPLLFDTHQLPEGDITDIV
HHHHCCCCCCCEEEEEECCCCEEEEEECCEEEEEECCCCCEEHHHHCCCCCCCCCHHHHH
ECSKGILLVYNTGRLVCLDTRTNEIKWQQDDLVGELGTDKQGIFTLFVDRDNDIWMYSPL
HCCCCEEEEEECCEEEEEECCCCCCEECHHHHHHCCCCCCCCEEEEEEECCCCEEEEECE
GIWVYNPEQEKWLSWLTNIIKRRSHNMVRAVSQDKQGRIWIGTDQDGIDILDKKTGEVRQ
EEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCCCHHHCCCCHHHHH
LRNKTGDERSLQNNTVMVLYEDSSETMWVGTYKKGISYFNECAFKFGAEYIGDISCIEED
HHHCCCCCCCCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHCHHHHCCCCEEEEC
KEGYVWLGTNDVGIIYWNSVTGNRAAFPQKGMDKLTTDAIVCILKAGDGKLWIGTFGGGL
CCCEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHCCCEEEEEEEECCCEEEEEECCCCE
ICYDNGRIIHYKKNIPERQNSLAHNNVLALAEDKQGIIWIGTLGGGVQSLNPKTGLFTTY
EEEECCEEEEEECCCCHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEE
NTTSAGLISDYVSSLCMGKEGSLWIGTAQGLSELDIETKKVVNLEGTKSGKEYFSDQNIS
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHCCCCHH
QVYEDSRGLIWIGTCEGLNVYNPKTDELIILGVEQGVSSPIISGIVEDGNENIWVTTARG
HHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCC
ITNVIPAVDLKTGRYIFHSCVYDDKDGLQNSGFNLRSIKKLSSGEILMGGLYGINRFRPD
HHHCCCCEECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCC
DIKYNKKRPSVMFTRLFLFNEEVGVGEEYEGRVILDKALNKVDQIKLSYEQNMFSVQFAS
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEHHHHCHHHHEEEEECCCEEEEEECC
DNYILPEKTEYAYKLEGFNEGWMTTAFGKVTYTNLAPGTYMLKVKAVNSDGYGGDEEASL
CCEECCCCCCCEEEECCCCCCCEEEEECCEEEEECCCCEEEEEEEEECCCCCCCCCCCEE
KIVIYPPFWRSVWAYVVYSLLLVAVLILGRYWILRGERDKFKKQQIKQEIERNQEKADMK
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHHHCEE
LKFFTHVGHELRTPLTLIISPLETLMKEYQSDAALMDKLNIVQRNALRLLNLVNQLLDFR
EEEHHHCCHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
KIDVNGYYLSLSDDDIISCIHTICDSFISLSEKKDISLIFHSAVPSLNMLFDGDKMREVM
EEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCHHHHHHH
MNLLSNALKFTCNGGRVDVSVGLVEGQDSREMLEIRVVDTGVGIKEENRERIFERFYQVD
HHHHHHHHEEEECCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCC
NPDMNISDGGGGLSIVRDFVTLHDGTVNVMDNTPVGCVFVIHIPVKRSESKPTKIEQVQV
CCCCEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEE
TDKPVEDISTLQIPEFYMASNAGEESEEEPNHIITIEGLEEDIRRLESGNTEEIAEEKNI
CCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHCCC
ETISAVAPQRATVIQLIEGEDNEMITHIIPPEELPEMVTAVPEEKSEQKLKTVWNHAYID
CCHHHCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCEEEE
FKPSGTAITSMDEKLINHAVKYVEDNIARSDLSVEELSKELGMSRVHLYKKLLAITGKTP
ECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCH
IEFIRIIRLQRAAQLLRGSQQNISEIAYQVGFNNPKYFSRYFKEEFGILPSAFQYRQGR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
GIRKKCLIITLLCFSSLMHASEFMFKHLEVKDGLSNNQVLDIFKDSEGFMWFATASGLN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCC
RYDGCQMTLFRSNNADPASLPDNYIKSIQEDYKGNLWILTGVGYVIYNSESETFDREVHA
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHH
WLCEVGIDGTPALVYIDHNKNMWFYIKGKGCYLYIPESQLLYPLLFDTHQLPEGDITDIV
HHHHCCCCCCCEEEEEECCCCEEEEEECCEEEEEECCCCCEEHHHHCCCCCCCCCHHHHH
ECSKGILLVYNTGRLVCLDTRTNEIKWQQDDLVGELGTDKQGIFTLFVDRDNDIWMYSPL
HCCCCEEEEEECCEEEEEECCCCCCEECHHHHHHCCCCCCCCEEEEEEECCCCEEEEECE
GIWVYNPEQEKWLSWLTNIIKRRSHNMVRAVSQDKQGRIWIGTDQDGIDILDKKTGEVRQ
EEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCCCHHHCCCCHHHHH
LRNKTGDERSLQNNTVMVLYEDSSETMWVGTYKKGISYFNECAFKFGAEYIGDISCIEED
HHHCCCCCCCCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHCHHHHCCCCEEEEC
KEGYVWLGTNDVGIIYWNSVTGNRAAFPQKGMDKLTTDAIVCILKAGDGKLWIGTFGGGL
CCCEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHCCCEEEEEEEECCCEEEEEECCCCE
ICYDNGRIIHYKKNIPERQNSLAHNNVLALAEDKQGIIWIGTLGGGVQSLNPKTGLFTTY
EEEECCEEEEEECCCCHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEE
NTTSAGLISDYVSSLCMGKEGSLWIGTAQGLSELDIETKKVVNLEGTKSGKEYFSDQNIS
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHCCCCHH
QVYEDSRGLIWIGTCEGLNVYNPKTDELIILGVEQGVSSPIISGIVEDGNENIWVTTARG
HHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCC
ITNVIPAVDLKTGRYIFHSCVYDDKDGLQNSGFNLRSIKKLSSGEILMGGLYGINRFRPD
HHHCCCCEECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCC
DIKYNKKRPSVMFTRLFLFNEEVGVGEEYEGRVILDKALNKVDQIKLSYEQNMFSVQFAS
CCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEHHHHCHHHHEEEEECCCEEEEEECC
DNYILPEKTEYAYKLEGFNEGWMTTAFGKVTYTNLAPGTYMLKVKAVNSDGYGGDEEASL
CCEECCCCCCCEEEECCCCCCCEEEEECCEEEEECCCCEEEEEEEEECCCCCCCCCCCEE
KIVIYPPFWRSVWAYVVYSLLLVAVLILGRYWILRGERDKFKKQQIKQEIERNQEKADMK
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHHHCEE
LKFFTHVGHELRTPLTLIISPLETLMKEYQSDAALMDKLNIVQRNALRLLNLVNQLLDFR
EEEHHHCCHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
KIDVNGYYLSLSDDDIISCIHTICDSFISLSEKKDISLIFHSAVPSLNMLFDGDKMREVM
EEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCHHHHHHH
MNLLSNALKFTCNGGRVDVSVGLVEGQDSREMLEIRVVDTGVGIKEENRERIFERFYQVD
HHHHHHHHEEEECCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCC
NPDMNISDGGGGLSIVRDFVTLHDGTVNVMDNTPVGCVFVIHIPVKRSESKPTKIEQVQV
CCCCEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEE
TDKPVEDISTLQIPEFYMASNAGEESEEEPNHIITIEGLEEDIRRLESGNTEEIAEEKNI
CCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHCCC
ETISAVAPQRATVIQLIEGEDNEMITHIIPPEELPEMVTAVPEEKSEQKLKTVWNHAYID
CCHHHCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCEEEE
FKPSGTAITSMDEKLINHAVKYVEDNIARSDLSVEELSKELGMSRVHLYKKLLAITGKTP
ECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCH
IEFIRIIRLQRAAQLLRGSQQNISEIAYQVGFNNPKYFSRYFKEEFGILPSAFQYRQGR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA