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The map label for this gene is 150004612

Identifier: 150004612

GI number: 150004612

Start: 2679926

End: 2682139

Strand: Reverse

Name: 150004612

Synonym: BVU_2069

Alternate gene names: NA

Gene position: 2682139-2679926 (Counterclockwise)

Preceding gene: 150004613

Following gene: 150004611

Centisome position: 51.95

GC content: 39.7

Gene sequence:

>2214_bases
ATGAAAAAAATGCATTTGGCAATCATTTGTCTTTTTACCGGTTGTACTATCTTTGCCCAAAACATAGAAGTACAGCCCAT
CCCTCAACAAGTTTCCAAACAAGACGGACAAATCAATTTACCTGAAACTTACCAACTCTTGGGAGAAACTGAAGCCAATC
CATATGCCGTACAAGAATTAAAAGATTTATTAGGTGGAAAACACCCGGCCAATACCGGTTTGCGCATTTATATAGGAGAA
AAAGGAGACAAGTCCATCCGCAAGTTTACTCGTCAGATCCCCAACCAAAAGGAAGGTTATTATCTATCCATCAATAATAA
GGAAATAATTCTGGCAGGAAACGATGAACGTGGAACCTACTATGCCTTGCAAACCTTAAAACAATTGCTCAAAGATAACC
AATTACCGGTAATAGAGATACAAGACTATCCGGCCATACGCTACCGTGGTGTCGTAGAAGGATTTTACGGGACCCCCTGG
AGCCATAATGCCCGTCTTCGCCAACTTCAATTTTATGGTGAAAACAAAATGAACACCTATATATACGGCCCTAAAGATGA
CCCTTACCATAGTTCTCCCAACTGGCGTCTGCCTTACCCCGAAAAAGAAGCAAAACAATTACAGGAATTAGTAAAAGTAG
CTCAAGAAAACGAAGTCGATTTTGTTTGGGCTATCCATCCGGGACAAGACATCAAATGGAATAAAGAAGACCGTGAATTA
TTATTGGCAAAATTTGAAAAGATGTATCATCTCGGTGTCCGTTCTTTTGCCGTCTTCTTTGATGATATTTCAGGAGAAGG
TACCAACCCTGTGAAACAAGCAGAACTGCTGAATTACATAGATGAACATTTTGTAAAAGTAAAACCGGATGTAACTCCCC
TTATCATGTGTCCTACAGAATACAATAAAAGTTGGTCCGACCCTGCTAAAGGATATCTTACTACTTTAGGAGACAAACTG
AATCCATCCATACAAATTATGTGGACAGGAGACCGGGTTATTTCCGATATTACCCAAGATGGTATTCAATGGATAAACGA
ACGGATTAAACGTCCGGCATATATATGGTGGAACTTTCCTGTTTCCGATTACGTTAGAGATCATCTGCTCATGGGACCAG
TATATGGAAACGATACTCAAATAGCCAATCAGATGTCTGGCTTTGTAACTAATCCGATGGAACATGCCGAGGCTTCTAAA
ATAGCCATTTATAGTGTAGCCTCATACGCTTGGAATCCAACAAAATATAACAGTGAAAAAACTTGGAAAGACGCTATTAT
GAACATTTTGCCCGATGCTGCCACTGAACTGGAATTCTTTGCCGCCCATAATTCGGACTTGGGCCCCAACGGACATAAAT
ATCGCCGAGAGGAATCTGTAAATCTCCAACCCACAGCGCAGAGCTTTACTGAAAGTTACATAAAAAATAAAACTTACACT
GAAAAAGACTTCTCTATTCTACAAGAAACCTTCAGCCAGATGGTTGAATCAAGTGATATTTTAGTCGCCCATGCTGATAA
AAATCCGATTATAGTAGAAATCATGCCTTGGCTTTATCAGTTCAAACTATTGGGTGAAACCGGAAATGAAGTACTGGCAA
TGGTCAAAGCATACGACAAAAATGACCAATCTTTATTTATGCGTAAATACAAACACGTGAAAGCCTTGCAACAACAAATG
TTTCAAATTGACCAGACATACAACCAAAACCCTTACCAGCCGGGTATAAAGACAGCAGGAAGAGTAATCAAGCCATTGAT
TGATCAAACTTTCGCCACCGTCACGCAATGCTATAACCAAAAATATAGCACACTGCTGAATGCTGAAACCGACTATATGC
CGCATAAACTAATAAGCGATATCAGTCAGATAAAGAACTTACCTTTACAGGTAAAGATAAACCGCATTCAGATTTCTCCG
GCGCTGGAAGTTATCAGATGGCCCGGTAATGGTTCATTGACTATCGAACTGGATCAAGTTTATCCCGGAGAAAATATAGA
GATAGATTTCGGGAAACCGGAAATCGAAACTTGGGGAAGTCTTGAGATATCTGCAAATGGAAAAGACTGGAGTAAAGTAC
ACTTTACACAAGAAAACAACCGACTGACTGCCAGTTTACAACAGAAACCAATAAAGGCAGTACGTTTTACCAACATGCAG
CATCAGGAACAAGAAATTTACCTCAGACGATTTATTATAACAATAGACAAATAA

Upstream 100 bases:

>100_bases
TACCTACTTTCCGAAGAAATAATACAATTAAAAGATGGAATTCTTTCTGTATAAATCGTATCTTTGCCATTGATTTATTA
ACCTTTTACCCCAACAGAAC

Downstream 100 bases:

>100_bases
AACAACTATAAATTATGGGCTTATTTAAATCCTTATTCGGCGGAAACAACACCCCCGAAACCGAAAAAGAGAAAAATGAT
AAAAAGAACTTCGAGATTTT

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; Beta-hexosaminidase; GH84; Hexosaminidase B; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MKKMHLAIICLFTGCTIFAQNIEVQPIPQQVSKQDGQINLPETYQLLGETEANPYAVQELKDLLGGKHPANTGLRIYIGE
KGDKSIRKFTRQIPNQKEGYYLSINNKEIILAGNDERGTYYALQTLKQLLKDNQLPVIEIQDYPAIRYRGVVEGFYGTPW
SHNARLRQLQFYGENKMNTYIYGPKDDPYHSSPNWRLPYPEKEAKQLQELVKVAQENEVDFVWAIHPGQDIKWNKEDREL
LLAKFEKMYHLGVRSFAVFFDDISGEGTNPVKQAELLNYIDEHFVKVKPDVTPLIMCPTEYNKSWSDPAKGYLTTLGDKL
NPSIQIMWTGDRVISDITQDGIQWINERIKRPAYIWWNFPVSDYVRDHLLMGPVYGNDTQIANQMSGFVTNPMEHAEASK
IAIYSVASYAWNPTKYNSEKTWKDAIMNILPDAATELEFFAAHNSDLGPNGHKYRREESVNLQPTAQSFTESYIKNKTYT
EKDFSILQETFSQMVESSDILVAHADKNPIIVEIMPWLYQFKLLGETGNEVLAMVKAYDKNDQSLFMRKYKHVKALQQQM
FQIDQTYNQNPYQPGIKTAGRVIKPLIDQTFATVTQCYNQKYSTLLNAETDYMPHKLISDISQIKNLPLQVKINRIQISP
ALEVIRWPGNGSLTIELDQVYPGENIEIDFGKPEIETWGSLEISANGKDWSKVHFTQENNRLTASLQQKPIKAVRFTNMQ
HQEQEIYLRRFIITIDK

Sequences:

>Translated_737_residues
MKKMHLAIICLFTGCTIFAQNIEVQPIPQQVSKQDGQINLPETYQLLGETEANPYAVQELKDLLGGKHPANTGLRIYIGE
KGDKSIRKFTRQIPNQKEGYYLSINNKEIILAGNDERGTYYALQTLKQLLKDNQLPVIEIQDYPAIRYRGVVEGFYGTPW
SHNARLRQLQFYGENKMNTYIYGPKDDPYHSSPNWRLPYPEKEAKQLQELVKVAQENEVDFVWAIHPGQDIKWNKEDREL
LLAKFEKMYHLGVRSFAVFFDDISGEGTNPVKQAELLNYIDEHFVKVKPDVTPLIMCPTEYNKSWSDPAKGYLTTLGDKL
NPSIQIMWTGDRVISDITQDGIQWINERIKRPAYIWWNFPVSDYVRDHLLMGPVYGNDTQIANQMSGFVTNPMEHAEASK
IAIYSVASYAWNPTKYNSEKTWKDAIMNILPDAATELEFFAAHNSDLGPNGHKYRREESVNLQPTAQSFTESYIKNKTYT
EKDFSILQETFSQMVESSDILVAHADKNPIIVEIMPWLYQFKLLGETGNEVLAMVKAYDKNDQSLFMRKYKHVKALQQQM
FQIDQTYNQNPYQPGIKTAGRVIKPLIDQTFATVTQCYNQKYSTLLNAETDYMPHKLISDISQIKNLPLQVKINRIQISP
ALEVIRWPGNGSLTIELDQVYPGENIEIDFGKPEIETWGSLEISANGKDWSKVHFTQENNRLTASLQQKPIKAVRFTNMQ
HQEQEIYLRRFIITIDK
>Mature_737_residues
MKKMHLAIICLFTGCTIFAQNIEVQPIPQQVSKQDGQINLPETYQLLGETEANPYAVQELKDLLGGKHPANTGLRIYIGE
KGDKSIRKFTRQIPNQKEGYYLSINNKEIILAGNDERGTYYALQTLKQLLKDNQLPVIEIQDYPAIRYRGVVEGFYGTPW
SHNARLRQLQFYGENKMNTYIYGPKDDPYHSSPNWRLPYPEKEAKQLQELVKVAQENEVDFVWAIHPGQDIKWNKEDREL
LLAKFEKMYHLGVRSFAVFFDDISGEGTNPVKQAELLNYIDEHFVKVKPDVTPLIMCPTEYNKSWSDPAKGYLTTLGDKL
NPSIQIMWTGDRVISDITQDGIQWINERIKRPAYIWWNFPVSDYVRDHLLMGPVYGNDTQIANQMSGFVTNPMEHAEASK
IAIYSVASYAWNPTKYNSEKTWKDAIMNILPDAATELEFFAAHNSDLGPNGHKYRREESVNLQPTAQSFTESYIKNKTYT
EKDFSILQETFSQMVESSDILVAHADKNPIIVEIMPWLYQFKLLGETGNEVLAMVKAYDKNDQSLFMRKYKHVKALQQQM
FQIDQTYNQNPYQPGIKTAGRVIKPLIDQTFATVTQCYNQKYSTLLNAETDYMPHKLISDISQIKNLPLQVKINRIQISP
ALEVIRWPGNGSLTIELDQVYPGENIEIDFGKPEIETWGSLEISANGKDWSKVHFTQENNRLTASLQQKPIKAVRFTNMQ
HQEQEIYLRRFIITIDK

Specific function: Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 84 family [H]

Homologues:

Organism=Homo sapiens, GI11024698, Length=306, Percent_Identity=34.9673202614379, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI215490056, Length=296, Percent_Identity=35.8108108108108, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI193211002, Length=277, Percent_Identity=33.9350180505415, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193211004, Length=277, Percent_Identity=33.9350180505415, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24648670, Length=274, Percent_Identity=34.3065693430657, Blast_Score=157, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR011496
- InterPro:   IPR017853 [H]

Pfam domain/function: PF02838 Glyco_hydro_20b; PF07555 NAGidase [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 85036; Mature: 85036

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMHLAIICLFTGCTIFAQNIEVQPIPQQVSKQDGQINLPETYQLLGETEANPYAVQEL
CCCCEEEHHHHHHCHHEEECCCCCCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHH
KDLLGGKHPANTGLRIYIGEKGDKSIRKFTRQIPNQKEGYYLSINNKEIILAGNDERGTY
HHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCHH
YALQTLKQLLKDNQLPVIEIQDYPAIRYRGVVEGFYGTPWSHNARLRQLQFYGENKMNTY
HHHHHHHHHHCCCCCCEEEECCCCCEEEEHEEECCCCCCCCCCCCEEEEEEECCCCCEEE
IYGPKDDPYHSSPNWRLPYPEKEAKQLQELVKVAQENEVDFVWAIHPGQDIKWNKEDREL
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
LLAKFEKMYHLGVRSFAVFFDDISGEGTNPVKQAELLNYIDEHFVKVKPDVTPLIMCPTE
HHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECCCC
YNKSWSDPAKGYLTTLGDKLNPSIQIMWTGDRVISDITQDGIQWINERIKRPAYIWWNFP
CCCCCCCCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
VSDYVRDHLLMGPVYGNDTQIANQMSGFVTNPMEHAEASKIAIYSVASYAWNPTKYNSEK
HHHHHHHHEEECCCCCCCHHHHHHHHCCCCCCHHHCCCCEEEEEEEHHHCCCCCCCCCCH
TWKDAIMNILPDAATELEFFAAHNSDLGPNGHKYRREESVNLQPTAQSFTESYIKNKTYT
HHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
EKDFSILQETFSQMVESSDILVAHADKNPIIVEIMPWLYQFKLLGETGNEVLAMVKAYDK
HHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHCC
NDQSLFMRKYKHVKALQQQMFQIDQTYNQNPYQPGIKTAGRVIKPLIDQTFATVTQCYNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KYSTLLNAETDYMPHKLISDISQIKNLPLQVKINRIQISPALEVIRWPGNGSLTIELDQV
HHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEEECCCCEEEEEEECC
YPGENIEIDFGKPEIETWGSLEISANGKDWSKVHFTQENNRLTASLQQKPIKAVRFTNMQ
CCCCCEEEECCCCCCCCCCCEEEECCCCCCEEEEEEECCCEEEEHHHHCCCHHHHHCCCC
HQEQEIYLRRFIITIDK
HHHHHHHEEEEEEEECC
>Mature Secondary Structure
MKKMHLAIICLFTGCTIFAQNIEVQPIPQQVSKQDGQINLPETYQLLGETEANPYAVQEL
CCCCEEEHHHHHHCHHEEECCCCCCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHH
KDLLGGKHPANTGLRIYIGEKGDKSIRKFTRQIPNQKEGYYLSINNKEIILAGNDERGTY
HHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCHH
YALQTLKQLLKDNQLPVIEIQDYPAIRYRGVVEGFYGTPWSHNARLRQLQFYGENKMNTY
HHHHHHHHHHCCCCCCEEEECCCCCEEEEHEEECCCCCCCCCCCCEEEEEEECCCCCEEE
IYGPKDDPYHSSPNWRLPYPEKEAKQLQELVKVAQENEVDFVWAIHPGQDIKWNKEDREL
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
LLAKFEKMYHLGVRSFAVFFDDISGEGTNPVKQAELLNYIDEHFVKVKPDVTPLIMCPTE
HHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECCCC
YNKSWSDPAKGYLTTLGDKLNPSIQIMWTGDRVISDITQDGIQWINERIKRPAYIWWNFP
CCCCCCCCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
VSDYVRDHLLMGPVYGNDTQIANQMSGFVTNPMEHAEASKIAIYSVASYAWNPTKYNSEK
HHHHHHHHEEECCCCCCCHHHHHHHHCCCCCCHHHCCCCEEEEEEEHHHCCCCCCCCCCH
TWKDAIMNILPDAATELEFFAAHNSDLGPNGHKYRREESVNLQPTAQSFTESYIKNKTYT
HHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
EKDFSILQETFSQMVESSDILVAHADKNPIIVEIMPWLYQFKLLGETGNEVLAMVKAYDK
HHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHCC
NDQSLFMRKYKHVKALQQQMFQIDQTYNQNPYQPGIKTAGRVIKPLIDQTFATVTQCYNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KYSTLLNAETDYMPHKLISDISQIKNLPLQVKINRIQISPALEVIRWPGNGSLTIELDQV
HHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEEECCCCEEEEEEECC
YPGENIEIDFGKPEIETWGSLEISANGKDWSKVHFTQENNRLTASLQQKPIKAVRFTNMQ
CCCCCEEEECCCCCCCCCCCEEEECCCCCCEEEEEEECCCEEEEHHHHCCCHHHHHCCCC
HQEQEIYLRRFIITIDK
HHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]