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The map label for this gene is yabD [H]

Identifier: 150004491

GI number: 150004491

Start: 2521666

End: 2522439

Strand: Direct

Name: yabD [H]

Synonym: BVU_1940

Alternate gene names: 150004491

Gene position: 2521666-2522439 (Clockwise)

Preceding gene: 150004490

Following gene: 150004492

Centisome position: 48.84

GC content: 40.83

Gene sequence:

>774_bases
ATGATTGACACGCATTCTCATTTGTTTGTTGAGGAGTTTGATGAGGATTTGCCGGCTGTGATAGAACGTGCTCGGGATTC
CGGAGTATCTAAAGTCTTTATGCCCAATATTGATGACACCACGGTGGAAGCGATGTTGAATGTCTGTACGGCATATAAGG
GGTATTGTTTTCCTATGATTGGATTTCATCCGACTTCTGTTGGGGCTGATTCGTTATTCCGTATTTATGAGATGAAAAAG
CTGCTTTCCGGTGAACATCCTTTTGTGGCTGTAGGTGAGGTGGGAATGGATTTGTATTGGGATAAGACATATTTGAAAGA
ACAACAGAAGGCGTTGGATATACAGATTCAATGGGCATTGGAATATCATCTGCCTTTGGTGTTGCATTGCCGTGAAGCTT
TTCCGGAGTTGTTTGAAGTGATGGAACCTTATAAAAAAACTGAGTTAAGCGGTATCTTTCATAGTTTTACGGGTGCTCTG
GAGGAAGCAGGGCAGGTTTTAGAGTATGCTCGTTTTTTCTTTGGAATCAATGGAGTCGTTACATTCAAGAAGAGTAGTCT
GGCTGAGGTTTTACCTCATATCCCCTTAGACAGAATTGTTCTTGAAACGGATTCTCCTTATTTGGCTCCTGTGCCTTTCA
GGGGAAAACGGAACGAGTCTTCTTATATAAAGAATGTAGCGATGAAACTTGCCGAAATCTATGGTCTGGATTTTAAAGAT
GTGGATAGAATTACTGCCAATAATGCTTTAAAAGTGTTCAAAATGGCTGAATAA

Upstream 100 bases:

>100_bases
GTCGAGGGGCTTTCGTTGTTGGAAAGTATAGCTGTGCCTTCTGAAAGAAAAGAAGAGCTGAAGTCTTTTGTTTGTCATTT
GATGAATAGAAAAGTATAAT

Downstream 100 bases:

>100_bases
GTTTTTAAAGTTTATTAATTTTGATAGGTAATTTAAATATTGGCAGGGCTAATTCTACGTAAGACGAAAAAAAAGAATAC
ATTTGTAGCTGAAATCGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIDTHSHLFVEEFDEDLPAVIERARDSGVSKVFMPNIDDTTVEAMLNVCTAYKGYCFPMIGFHPTSVGADSLFRIYEMKK
LLSGEHPFVAVGEVGMDLYWDKTYLKEQQKALDIQIQWALEYHLPLVLHCREAFPELFEVMEPYKKTELSGIFHSFTGAL
EEAGQVLEYARFFFGINGVVTFKKSSLAEVLPHIPLDRIVLETDSPYLAPVPFRGKRNESSYIKNVAMKLAEIYGLDFKD
VDRITANNALKVFKMAE

Sequences:

>Translated_257_residues
MIDTHSHLFVEEFDEDLPAVIERARDSGVSKVFMPNIDDTTVEAMLNVCTAYKGYCFPMIGFHPTSVGADSLFRIYEMKK
LLSGEHPFVAVGEVGMDLYWDKTYLKEQQKALDIQIQWALEYHLPLVLHCREAFPELFEVMEPYKKTELSGIFHSFTGAL
EEAGQVLEYARFFFGINGVVTFKKSSLAEVLPHIPLDRIVLETDSPYLAPVPFRGKRNESSYIKNVAMKLAEIYGLDFKD
VDRITANNALKVFKMAE
>Mature_257_residues
MIDTHSHLFVEEFDEDLPAVIERARDSGVSKVFMPNIDDTTVEAMLNVCTAYKGYCFPMIGFHPTSVGADSLFRIYEMKK
LLSGEHPFVAVGEVGMDLYWDKTYLKEQQKALDIQIQWALEYHLPLVLHCREAFPELFEVMEPYKKTELSGIFHSFTGAL
EEAGQVLEYARFFFGINGVVTFKKSSLAEVLPHIPLDRIVLETDSPYLAPVPFRGKRNESSYIKNVAMKLAEIYGLDFKD
VDRITANNALKVFKMAE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=28.4090909090909, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=28.030303030303, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=28.1481481481481, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=27.6679841897233, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI14042943, Length=275, Percent_Identity=26.9090909090909, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI225903424, Length=129, Percent_Identity=38.7596899224806, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI225903439, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=27.3127753303965, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1787342, Length=196, Percent_Identity=32.1428571428571, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=27.906976744186, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI48994985, Length=265, Percent_Identity=26.4150943396226, Blast_Score=103, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=27.4647887323944, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=28.8973384030418, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=186, Percent_Identity=31.1827956989247, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565396, Length=183, Percent_Identity=30.6010928961749, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221330018, Length=213, Percent_Identity=30.9859154929577, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586117, Length=213, Percent_Identity=30.9859154929577, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648690, Length=289, Percent_Identity=25.6055363321799, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29293; Mature: 29293

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHSHLFVEEFDEDLPAVIERARDSGVSKVFMPNIDDTTVEAMLNVCTAYKGYCFPMI
CCCCCCHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEEC
GFHPTSVGADSLFRIYEMKKLLSGEHPFVAVGEVGMDLYWDKTYLKEQQKALDIQIQWAL
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECHHHHHHHHHHEEEEEEEEE
EYHLPLVLHCREAFPELFEVMEPYKKTELSGIFHSFTGALEEAGQVLEYARFFFGINGVV
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
TFKKSSLAEVLPHIPLDRIVLETDSPYLAPVPFRGKRNESSYIKNVAMKLAEIYGLDFKD
EECHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VDRITANNALKVFKMAE
HHHHHCCCCEEEEEECC
>Mature Secondary Structure
MIDTHSHLFVEEFDEDLPAVIERARDSGVSKVFMPNIDDTTVEAMLNVCTAYKGYCFPMI
CCCCCCHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEEC
GFHPTSVGADSLFRIYEMKKLLSGEHPFVAVGEVGMDLYWDKTYLKEQQKALDIQIQWAL
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECHHHHHHHHHHEEEEEEEEE
EYHLPLVLHCREAFPELFEVMEPYKKTELSGIFHSFTGALEEAGQVLEYARFFFGINGVV
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
TFKKSSLAEVLPHIPLDRIVLETDSPYLAPVPFRGKRNESSYIKNVAMKLAEIYGLDFKD
EECHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VDRITANNALKVFKMAE
HHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]