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The map label for this gene is idsA [H]

Identifier: 150004490

GI number: 150004490

Start: 2520687

End: 2521664

Strand: Direct

Name: idsA [H]

Synonym: BVU_1939

Alternate gene names: 150004490

Gene position: 2520687-2521664 (Clockwise)

Preceding gene: 150004489

Following gene: 150004491

Centisome position: 48.82

GC content: 40.08

Gene sequence:

>978_bases
ATGGCTTTTTCTGCAGACCAGTTATTGGAAAAGGTAAATACTTATCTTGCTACGATGCCTTATGTGCGCGAACCAAAAGG
ATTGTATGCTCCTATAGAGTATGTCTTGTCATTAGGCGGTAAACGTATCCGTCCTGTTTTGATGTTGCTTTCCTATCAGC
TTTACAAAGAGAATGTGGATGATATTTTACCACAAGCGGCAGGTATAGAGACTTATCATAATTATACATTGTTGCATGAT
GATTTGATGGATTGTGCGGATATGCGCAGAAACAAGCCTACCGTGCATAAGGTTTGGGATGAGAATACGGCTATTCTTTC
GGGGGATGCCATGCTGGTGTTGGCTTATCGGCTGATGAATAATTGTCCGGAGCGTTATTTGAGGCAAGTGATGGATATTT
TCAGTCAGACTGCTTTGGAAATTTGTGAAGGACAGCAGTGGGATATGGAATTTGAAACCCGGAATGATGTTACTGTTCCC
GAATATATGGAGATGATTCGTTTAAAGACATCGGTACTTTTGTCTGCTGCGTTAAAAATTGGTGCTGTATTAGGGGGGGC
TTCGGAAGATGATGCCCGCAAATTATACGATTTCGGTATCAAAATGGGATTGGCATTCCAGTTACAGGATGATTATCTGG
ATGTGTATGGGGATTCGAAAGTGTTTGGAAAAAATATAGGTGGAGATATTTTATGCAATAAGAAGACTTTTATGCTGATC
AATGCGTTGGCTTTGGCAGATGGGATACAACGGAAGGAGTTGGAAAAATGGATAGCTTCTACTGCTTTTTGTCCGGAAGA
AAAGATAAAAGCTGTAACAGCTCTTTATGATAAGATAGGCATCGGCGGAATTTGTGAAGAAAAGATTAACGCTTATTATG
TCGAGGGGCTTTCGTTGTTGGAAAGTATAGCTGTGCCTTCTGAAAGAAAAGAAGAGCTGAAGTCTTTTGTTTGTCATTTG
ATGAATAGAAAAGTATAA

Upstream 100 bases:

>100_bases
AACTTTCAAATTACAGTAATAAAATACTTTAATATCTTAATTAAGAGGCTGCCTTTAAAAAGCAGCCTCTTTTTCTAGAA
CCCCTTAATCAAAATAATTT

Downstream 100 bases:

>100_bases
TATGATTGACACGCATTCTCATTTGTTTGTTGAGGAGTTTGATGAGGATTTGCCGGCTGTGATAGAACGTGCTCGGGATT
CCGGAGTATCTAAAGTCTTT

Product: putative isoprenoid biosynthesis related protein

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAFSADQLLEKVNTYLATMPYVREPKGLYAPIEYVLSLGGKRIRPVLMLLSYQLYKENVDDILPQAAGIETYHNYTLLHD
DLMDCADMRRNKPTVHKVWDENTAILSGDAMLVLAYRLMNNCPERYLRQVMDIFSQTALEICEGQQWDMEFETRNDVTVP
EYMEMIRLKTSVLLSAALKIGAVLGGASEDDARKLYDFGIKMGLAFQLQDDYLDVYGDSKVFGKNIGGDILCNKKTFMLI
NALALADGIQRKELEKWIASTAFCPEEKIKAVTALYDKIGIGGICEEKINAYYVEGLSLLESIAVPSERKEELKSFVCHL
MNRKV

Sequences:

>Translated_325_residues
MAFSADQLLEKVNTYLATMPYVREPKGLYAPIEYVLSLGGKRIRPVLMLLSYQLYKENVDDILPQAAGIETYHNYTLLHD
DLMDCADMRRNKPTVHKVWDENTAILSGDAMLVLAYRLMNNCPERYLRQVMDIFSQTALEICEGQQWDMEFETRNDVTVP
EYMEMIRLKTSVLLSAALKIGAVLGGASEDDARKLYDFGIKMGLAFQLQDDYLDVYGDSKVFGKNIGGDILCNKKTFMLI
NALALADGIQRKELEKWIASTAFCPEEKIKAVTALYDKIGIGGICEEKINAYYVEGLSLLESIAVPSERKEELKSFVCHL
MNRKV
>Mature_324_residues
AFSADQLLEKVNTYLATMPYVREPKGLYAPIEYVLSLGGKRIRPVLMLLSYQLYKENVDDILPQAAGIETYHNYTLLHDD
LMDCADMRRNKPTVHKVWDENTAILSGDAMLVLAYRLMNNCPERYLRQVMDIFSQTALEICEGQQWDMEFETRNDVTVPE
YMEMIRLKTSVLLSAALKIGAVLGGASEDDARKLYDFGIKMGLAFQLQDDYLDVYGDSKVFGKNIGGDILCNKKTFMLIN
ALALADGIQRKELEKWIASTAFCPEEKIKAVTALYDKIGIGGICEEKINAYYVEGLSLLESIAVPSERKEELKSFVCHLM
NRKV

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=209, Percent_Identity=29.6650717703349, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI209571584, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI209571582, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503685, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4758430, Length=221, Percent_Identity=27.1493212669683, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI83700220, Length=221, Percent_Identity=27.1493212669683, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789578, Length=210, Percent_Identity=34.2857142857143, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786623, Length=243, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17505681, Length=229, Percent_Identity=24.0174672489083, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322294, Length=287, Percent_Identity=28.9198606271777, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319475, Length=221, Percent_Identity=28.9592760180996, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325188, Length=221, Percent_Identity=24.4343891402715, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24651612, Length=207, Percent_Identity=28.9855072463768, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17137582, Length=265, Percent_Identity=29.4339622641509, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36821; Mature: 36690

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSADQLLEKVNTYLATMPYVREPKGLYAPIEYVLSLGGKRIRPVLMLLSYQLYKENVD
CCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHH
DILPQAAGIETYHNYTLLHDDLMDCADMRRNKPTVHKVWDENTAILSGDAMLVLAYRLMN
HHCCCCCCCHHHCCEEEHHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCHHHHHHHHHHH
NCPERYLRQVMDIFSQTALEICEGQQWDMEFETRNDVTVPEYMEMIRLKTSVLLSAALKI
HCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GAVLGGASEDDARKLYDFGIKMGLAFQLQDDYLDVYGDSKVFGKNIGGDILCNKKTFMLI
HHHHCCCCCHHHHHHHHHHHHHCEEEEEECCHHHHCCCCCHHCCCCCCCEEECCHHHHHH
NALALADGIQRKELEKWIASTAFCPEEKIKAVTALYDKIGIGGICEEKINAYYVEGLSLL
HHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ESIAVPSERKEELKSFVCHLMNRKV
HHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFSADQLLEKVNTYLATMPYVREPKGLYAPIEYVLSLGGKRIRPVLMLLSYQLYKENVD
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHH
DILPQAAGIETYHNYTLLHDDLMDCADMRRNKPTVHKVWDENTAILSGDAMLVLAYRLMN
HHCCCCCCCHHHCCEEEHHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCHHHHHHHHHHH
NCPERYLRQVMDIFSQTALEICEGQQWDMEFETRNDVTVPEYMEMIRLKTSVLLSAALKI
HCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GAVLGGASEDDARKLYDFGIKMGLAFQLQDDYLDVYGDSKVFGKNIGGDILCNKKTFMLI
HHHHCCCCCHHHHHHHHHHHHHCEEEEEECCHHHHCCCCCHHCCCCCCCEEECCHHHHHH
NALALADGIQRKELEKWIASTAFCPEEKIKAVTALYDKIGIGGICEEKINAYYVEGLSLL
HHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ESIAVPSERKEELKSFVCHLMNRKV
HHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]