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The map label for this gene is pyrH [H]

Identifier: 150004426

GI number: 150004426

Start: 2447573

End: 2448283

Strand: Reverse

Name: pyrH [H]

Synonym: BVU_1873

Alternate gene names: 150004426

Gene position: 2448283-2447573 (Counterclockwise)

Preceding gene: 150004427

Following gene: 150004425

Centisome position: 47.42

GC content: 46.27

Gene sequence:

>711_bases
ATGGCAAGATTTAAAAGAATTCTACTGAAGCTGAGCGGCGAAAGCCTGATGGGCGAAAAGCAATATGGTATAGACGAAAA
ACGTCTGGGTGAATATGCGCAACAAATCAAGGAAATACACGACCTTGGCGTACAAATAGGTATTGTAATCGGTGGTGGAA
ACATCTTCCGGGGGCTGAGCGGAGCTTCCAAAGGTTTTGACCGTGTAAAAGGTGACCAAATGGGGATGTTGGCAACCGTT
ATCAACAGCTTGGGATTGAGTTCCGCATTGGGAGCGGCCGGAGTCAAGGCACGTGTATTGACAGCTATCCGCATGGAACC
CATCGGTGAGTTTTACAACAAATGGAAAGCGATTGAAGCGATGGAAAACGGAGAAGTTGTGATTATGTCTGCCGGAACAG
GCAATCCGTTTTTTACTACCGATACCGGGTCTTCCCTGCGTGGTATCGAGATAGAAGCCGATGTGATGTTGAAAGGAACA
CGCGTGGACGGCATTTATACAGCTGATCCGGAAAAAGACCCCACTGCTACGAAATTTGACGATATCACCTACGATGAGGT
ATTGAAGCGCGGTTTGAAAGTAATGGATCTTACAGCAACCTGCATGTGCAAGGAAAACAACCTGCCCATTATCGTTTTCG
ACATGGACACAGTAGGTAACCTGAAAAAAGTAATGACCGGTGAAAATATAGGAACACTGGTACACAACTGA

Upstream 100 bases:

>100_bases
GAGTAATGCAAGGAGTCATGGGAAGAAATATTTTAGGATATAAAACAAGTAAAAAAGATTAATATTTTTATCTTTGCAAA
AAACTAAAAGACAAACCAAT

Downstream 100 bases:

>100_bases
TTTTCTCATCAAGTTCATCCATTTGTCATTCCTTATTTCCTTCTAAATGACAGATGGGTGAACAGTTTTTCTCTGTCTTA
CCATTTTTTCCACAAATTCG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MARFKRILLKLSGESLMGEKQYGIDEKRLGEYAQQIKEIHDLGVQIGIVIGGGNIFRGLSGASKGFDRVKGDQMGMLATV
INSLGLSSALGAAGVKARVLTAIRMEPIGEFYNKWKAIEAMENGEVVIMSAGTGNPFFTTDTGSSLRGIEIEADVMLKGT
RVDGIYTADPEKDPTATKFDDITYDEVLKRGLKVMDLTATCMCKENNLPIIVFDMDTVGNLKKVMTGENIGTLVHN

Sequences:

>Translated_236_residues
MARFKRILLKLSGESLMGEKQYGIDEKRLGEYAQQIKEIHDLGVQIGIVIGGGNIFRGLSGASKGFDRVKGDQMGMLATV
INSLGLSSALGAAGVKARVLTAIRMEPIGEFYNKWKAIEAMENGEVVIMSAGTGNPFFTTDTGSSLRGIEIEADVMLKGT
RVDGIYTADPEKDPTATKFDDITYDEVLKRGLKVMDLTATCMCKENNLPIIVFDMDTVGNLKKVMTGENIGTLVHN
>Mature_235_residues
ARFKRILLKLSGESLMGEKQYGIDEKRLGEYAQQIKEIHDLGVQIGIVIGGGNIFRGLSGASKGFDRVKGDQMGMLATVI
NSLGLSSALGAAGVKARVLTAIRMEPIGEFYNKWKAIEAMENGEVVIMSAGTGNPFFTTDTGSSLRGIEIEADVMLKGTR
VDGIYTADPEKDPTATKFDDITYDEVLKRGLKVMDLTATCMCKENNLPIIVFDMDTVGNLKKVMTGENIGTLVHN

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=55.4112554112554, Blast_Score=261, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25574; Mature: 25443

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFKRILLKLSGESLMGEKQYGIDEKRLGEYAQQIKEIHDLGVQIGIVIGGGNIFRGLS
CCHHHHHHHHCCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHCCC
GASKGFDRVKGDQMGMLATVINSLGLSSALGAAGVKARVLTAIRMEPIGEFYNKWKAIEA
CCCCCHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MENGEVVIMSAGTGNPFFTTDTGSSLRGIEIEADVMLKGTRVDGIYTADPEKDPTATKFD
CCCCCEEEEECCCCCCEEEECCCCCEECEEEEEEEEEEEEEECCEEECCCCCCCCCCCCC
DITYDEVLKRGLKVMDLTATCMCKENNLPIIVFDMDTVGNLKKVMTGENIGTLVHN
CCCHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ARFKRILLKLSGESLMGEKQYGIDEKRLGEYAQQIKEIHDLGVQIGIVIGGGNIFRGLS
CHHHHHHHHCCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHCCC
GASKGFDRVKGDQMGMLATVINSLGLSSALGAAGVKARVLTAIRMEPIGEFYNKWKAIEA
CCCCCHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MENGEVVIMSAGTGNPFFTTDTGSSLRGIEIEADVMLKGTRVDGIYTADPEKDPTATKFD
CCCCCEEEEECCCCCCEEEECCCCCEECEEEEEEEEEEEEEECCEEECCCCCCCCCCCCC
DITYDEVLKRGLKVMDLTATCMCKENNLPIIVFDMDTVGNLKKVMTGENIGTLVHN
CCCHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA