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The map label for this gene is ltaE [H]

Identifier: 150004254

GI number: 150004254

Start: 2188825

End: 2189841

Strand: Reverse

Name: ltaE [H]

Synonym: BVU_1700

Alternate gene names: 150004254

Gene position: 2189841-2188825 (Counterclockwise)

Preceding gene: 150004258

Following gene: 150004252

Centisome position: 42.41

GC content: 42.38

Gene sequence:

>1017_bases
ATGAGAAGTTTTGCATCTGACAATAATTCAAGTGTACATCCCCGCATCATGGAAGCGTTAATGAAGGCCAATAACGGACA
TGCACTTGGCTATGGAGATGATCCATGGACAGAAGAAGCCGCCCACAAAGTGAAAGAACAATTTTCACGTCCATGTGAAG
CACTGTTTGTTTTTAATGGCACAGGCAGTAATACTATGGCGCTGCAAATAATGACCCGTCCTTACCATATTATCTTCTGT
GCCGACACAGCTCACATTGCTGTAGATGAATGTGGTGCCCCCAGTAAAGCGACTGGCTGTTTCATGCGCACAATTCCTAC
TCCGGATGGCAAACTGACTCCGGAATTACTAAAACCATTTATGGTTAACTTTGGTATAGAACACCATTCTCAGCCCGGAG
CAATTTACCTAAGTCAATGTAGTGAATTAGGAACAATTTATAAACCAGAAGAAATATGCACATTGACAGAATTTGCACAC
CGGCATGGACTGTTTGTGCATATGGACGGTGCCCGTATCTCTAATGCCGCGGCAGCATTGGGAATGAGTCTTGATGATAT
ATCAGGAGCTTGCGGAGTTGACACATTGACTTTGGGAGGAACAAAGAACGGACTGATGGGAGCCGAATGTGTAGTGATTT
TCAATCAGGATTTGATAAAGGAAGCACGTTATGCCAGAAAACAATCTTGCCAATTGGCCAGCAAAATGCGTTATATCTCT
TGCCAGTTCACAGCCTTCCTTGAAGATAACCTATGGTTAACATGCGCACAACATGCCAACGCAATGGCGCAACGCTTGTA
CAAGAAACTTTCCACAATGCCTGATATAAAGTTTACCCAAACAGTGGAGAGCAACCAATTATTCTTCATCATGCCGCGTG
AAAAAGAAGATAAGCTACAAGAATATTATCATTTCTACTTTTGGAACGAAACCATAGGAGAAATGAGACTTGTTACCTCT
TTCGATACAACAGAAGAAGATGTCGACAAACTGATAGCTTGCATAAAGACTCTATAA

Upstream 100 bases:

>100_bases
GCATGATACTCCTTTTGCGTATTTATTTCAATGACGTTTCATTGCATTTTGTTGAAAAAGCTCCTACCTTTACAAATAAA
TTGTAAAATAGAAAAAGAAT

Downstream 100 bases:

>100_bases
TCATCTCCCGGTTCTCTATCAGGGCAGGCCTTCAGACCTGCCTGTTCTATTTCCAGTCCCTATTCCAAGGCATAAGTACC
CGGTGAGGGTTTCCGGACCT

Product: low-specificity L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRSFASDNNSSVHPRIMEALMKANNGHALGYGDDPWTEEAAHKVKEQFSRPCEALFVFNGTGSNTMALQIMTRPYHIIFC
ADTAHIAVDECGAPSKATGCFMRTIPTPDGKLTPELLKPFMVNFGIEHHSQPGAIYLSQCSELGTIYKPEEICTLTEFAH
RHGLFVHMDGARISNAAAALGMSLDDISGACGVDTLTLGGTKNGLMGAECVVIFNQDLIKEARYARKQSCQLASKMRYIS
CQFTAFLEDNLWLTCAQHANAMAQRLYKKLSTMPDIKFTQTVESNQLFFIMPREKEDKLQEYYHFYFWNETIGEMRLVTS
FDTTEEDVDKLIACIKTL

Sequences:

>Translated_338_residues
MRSFASDNNSSVHPRIMEALMKANNGHALGYGDDPWTEEAAHKVKEQFSRPCEALFVFNGTGSNTMALQIMTRPYHIIFC
ADTAHIAVDECGAPSKATGCFMRTIPTPDGKLTPELLKPFMVNFGIEHHSQPGAIYLSQCSELGTIYKPEEICTLTEFAH
RHGLFVHMDGARISNAAAALGMSLDDISGACGVDTLTLGGTKNGLMGAECVVIFNQDLIKEARYARKQSCQLASKMRYIS
CQFTAFLEDNLWLTCAQHANAMAQRLYKKLSTMPDIKFTQTVESNQLFFIMPREKEDKLQEYYHFYFWNETIGEMRLVTS
FDTTEEDVDKLIACIKTL
>Mature_338_residues
MRSFASDNNSSVHPRIMEALMKANNGHALGYGDDPWTEEAAHKVKEQFSRPCEALFVFNGTGSNTMALQIMTRPYHIIFC
ADTAHIAVDECGAPSKATGCFMRTIPTPDGKLTPELLKPFMVNFGIEHHSQPGAIYLSQCSELGTIYKPEEICTLTEFAH
RHGLFVHMDGARISNAAAALGMSLDDISGACGVDTLTLGGTKNGLMGAECVVIFNQDLIKEARYARKQSCQLASKMRYIS
CQFTAFLEDNLWLTCAQHANAMAQRLYKKLSTMPDIKFTQTVESNQLFFIMPREKEDKLQEYYHFYFWNETIGEMRLVTS
FDTTEEDVDKLIACIKTL

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=226, Percent_Identity=28.3185840707965, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37851; Mature: 37851

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFASDNNSSVHPRIMEALMKANNGHALGYGDDPWTEEAAHKVKEQFSRPCEALFVFNG
CCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEEC
TGSNTMALQIMTRPYHIIFCADTAHIAVDECGAPSKATGCFMRTIPTPDGKLTPELLKPF
CCCCEEEEEEEECCEEEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHH
MVNFGIEHHSQPGAIYLSQCSELGTIYKPEEICTLTEFAHRHGLFVHMDGARISNAAAAL
HHHCCCCCCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
GMSLDDISGACGVDTLTLGGTKNGLMGAECVVIFNQDLIKEARYARKQSCQLASKMRYIS
CCCHHHCCCCCCCCEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEE
CQFTAFLEDNLWLTCAQHANAMAQRLYKKLSTMPDIKFTQTVESNQLFFIMPREKEDKLQ
EEEEEEECCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHH
EYYHFYFWNETIGEMRLVTSFDTTEEDVDKLIACIKTL
HHHEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSFASDNNSSVHPRIMEALMKANNGHALGYGDDPWTEEAAHKVKEQFSRPCEALFVFNG
CCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEEC
TGSNTMALQIMTRPYHIIFCADTAHIAVDECGAPSKATGCFMRTIPTPDGKLTPELLKPF
CCCCEEEEEEEECCEEEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHH
MVNFGIEHHSQPGAIYLSQCSELGTIYKPEEICTLTEFAHRHGLFVHMDGARISNAAAAL
HHHCCCCCCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
GMSLDDISGACGVDTLTLGGTKNGLMGAECVVIFNQDLIKEARYARKQSCQLASKMRYIS
CCCHHHCCCCCCCCEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEE
CQFTAFLEDNLWLTCAQHANAMAQRLYKKLSTMPDIKFTQTVESNQLFFIMPREKEDKLQ
EEEEEEECCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHH
EYYHFYFWNETIGEMRLVTSFDTTEEDVDKLIACIKTL
HHHEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]