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The map label for this gene is asnC [H]

Identifier: 150004187

GI number: 150004187

Start: 2115044

End: 2116447

Strand: Direct

Name: asnC [H]

Synonym: BVU_1628

Alternate gene names: 150004187

Gene position: 2115044-2116447 (Clockwise)

Preceding gene: 150004186

Following gene: 150004188

Centisome position: 40.96

GC content: 43.16

Gene sequence:

>1404_bases
ATGGAAAAAATTAGTAGAACAAAGATTGTTGACTTGCTGAAGCGCCGTGATTTTGGTGCGATGGTCAATGTAAAAGGTTG
GGTTCGTACCCGCCGCGGTAGCAAACAGGTAAATTTTATCGCCCTGAATGACGGTTCTACAATAAATAATGTGCAGATTG
TTGTTGATTTGGCAAACTTTGACGAAGAAATGTTGAAGCAGATCACCACCGGTGCATGTATCAGTGTGAACGGTGAGTTG
ACCGAATCCATTGGCTCTGGTCAGGCTGCCGAAGTTCAAGCGCGTGGAATCGAAGTATTAGGTACTTGTGATAATACTTA
TCCGTTACAGAAGAAAGGTCATACGATGGAGTTTCTTCGTGAGATCGCTCATTTGCGTCCCCGTACCAATACATTTGGAG
CTGTATTCCGCATCCGCCACAACATGGCTATCGCTATCCATAAGTTCTTCCATGAACGTGGTTTCTTCTATTTTCATACA
CCTATTATCACAGCATCCGATTGTGAAGGTGCGGGACAGATGTTCCAGGTTACTACCAAGAATCTTTATGATTTGAAGAA
AGATGAAAACGGAGCGATTATTTATGATGATGATTTCTTTGGCAAACAAGCCAGTTTGACGGTTTCCGGACAGTTGGAAG
GTGAATTGGCTGCTACTGCTTTGGGGGCTATTTATACATTTGGACCTACATTCCGTGCGGAGAACTCCAATACGCCGCGT
CACTTGGCCGAGTTTTGGATGATTGAACCTGAGGTTGCGTTCAATGATATTACTGATAATATGGATTTGGCCGAAGACTT
TATTAAATATTGTGTACAGTGGGCGCTTGACAACTGCTATGATGATGTGAAGTTCTTGAACGATATGTTCGATAAAGGAT
TGATAGAACGTTTGCAGGGCGTGCTGAAGGAAGAATTTGTCCGTCTGCCTTATACGGAAGGTATCAAGATACTGGAGGAA
GCTGTAGTAAAAGGTCATAAATTTGAATTCCCGGTATATTGGGGAGTAGACTTAGCCTCTGAACATGAACGTTATTTGGT
GGAAGAGCACTTTAAACGTCCTGTAATCCTGACAGACTATCCGAAAGAAATCAAGGCATTCTATATGAAGCAGAATGAGG
ATGGCAAGACGGTGCGTGCAATGGATGTATTATTCCCGAAGATTGGCGAAATAATAGGTGGTTCTGAACGTGAGGCTGAT
TATGACAAATTGATGACCCGCATTCAGGAACTGGGAATTCCGATGAAGGATATGTGGTGGTATCTGGATACCCGCAAGTT
TGGTTCATGTCCTCATTCTGGTTTTGGACTTGGTTTTGAACGGTTGTTGCTGTTTGTTACCGGTATGACCAATATTCGTG
ATGTGATACCTTTCCCACGTACTCCGCGCAATGCTGAATTCTAA

Upstream 100 bases:

>100_bases
AAAGGTTTGCGTCGCGGTGACTGGCGTTACCTGACGGAACAAGAAGTGAACATGCTCCGCATGGGCTCATTTGAATAATA
AACAATAAAGAGACAAAACA

Downstream 100 bases:

>100_bases
TTGTAGGAAATAATAATTCAAAAAATCCTGCCCTATAACATAGAGCAGGATTTTTTTTGTGTTTAACTGTAAAAAAGTTA
TTTGAAAAGCAGAAAGTTTG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEKISRTKIVDLLKRRDFGAMVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDLANFDEEMLKQITTGACISVNGEL
TESIGSGQAAEVQARGIEVLGTCDNTYPLQKKGHTMEFLREIAHLRPRTNTFGAVFRIRHNMAIAIHKFFHERGFFYFHT
PIITASDCEGAGQMFQVTTKNLYDLKKDENGAIIYDDDFFGKQASLTVSGQLEGELAATALGAIYTFGPTFRAENSNTPR
HLAEFWMIEPEVAFNDITDNMDLAEDFIKYCVQWALDNCYDDVKFLNDMFDKGLIERLQGVLKEEFVRLPYTEGIKILEE
AVVKGHKFEFPVYWGVDLASEHERYLVEEHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREAD
YDKLMTRIQELGIPMKDMWWYLDTRKFGSCPHSGFGLGFERLLLFVTGMTNIRDVIPFPRTPRNAEF

Sequences:

>Translated_467_residues
MEKISRTKIVDLLKRRDFGAMVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDLANFDEEMLKQITTGACISVNGEL
TESIGSGQAAEVQARGIEVLGTCDNTYPLQKKGHTMEFLREIAHLRPRTNTFGAVFRIRHNMAIAIHKFFHERGFFYFHT
PIITASDCEGAGQMFQVTTKNLYDLKKDENGAIIYDDDFFGKQASLTVSGQLEGELAATALGAIYTFGPTFRAENSNTPR
HLAEFWMIEPEVAFNDITDNMDLAEDFIKYCVQWALDNCYDDVKFLNDMFDKGLIERLQGVLKEEFVRLPYTEGIKILEE
AVVKGHKFEFPVYWGVDLASEHERYLVEEHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREAD
YDKLMTRIQELGIPMKDMWWYLDTRKFGSCPHSGFGLGFERLLLFVTGMTNIRDVIPFPRTPRNAEF
>Mature_467_residues
MEKISRTKIVDLLKRRDFGAMVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDLANFDEEMLKQITTGACISVNGEL
TESIGSGQAAEVQARGIEVLGTCDNTYPLQKKGHTMEFLREIAHLRPRTNTFGAVFRIRHNMAIAIHKFFHERGFFYFHT
PIITASDCEGAGQMFQVTTKNLYDLKKDENGAIIYDDDFFGKQASLTVSGQLEGELAATALGAIYTFGPTFRAENSNTPR
HLAEFWMIEPEVAFNDITDNMDLAEDFIKYCVQWALDNCYDDVKFLNDMFDKGLIERLQGVLKEEFVRLPYTEGIKILEE
AVVKGHKFEFPVYWGVDLASEHERYLVEEHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREAD
YDKLMTRIQELGIPMKDMWWYLDTRKFGSCPHSGFGLGFERLLLFVTGMTNIRDVIPFPRTPRNAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=453, Percent_Identity=41.7218543046358, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI4758762, Length=456, Percent_Identity=30.0438596491228, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI45439306, Length=474, Percent_Identity=26.1603375527426, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1787161, Length=470, Percent_Identity=55.3191489361702, Blast_Score=533, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI17556372, Length=425, Percent_Identity=30.8235294117647, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI71984122, Length=466, Percent_Identity=30.0429184549356, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=498, Percent_Identity=24.6987951807229, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319872, Length=463, Percent_Identity=36.9330453563715, Blast_Score=305, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6321807, Length=468, Percent_Identity=30.5555555555556, Blast_Score=202, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6323011, Length=345, Percent_Identity=28.1159420289855, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19922416, Length=467, Percent_Identity=34.0471092077088, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI19921528, Length=460, Percent_Identity=29.7826086956522, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17136276, Length=481, Percent_Identity=25.5717255717256, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53430; Mature: 53430

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKISRTKIVDLLKRRDFGAMVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDLANF
CCCCHHHHHHHHHHHCCCCCEEECHHHHEECCCCCEEEEEEECCCCCCCCEEEEEEHHCC
DEEMLKQITTGACISVNGELTESIGSGQAAEVQARGIEVLGTCDNTYPLQKKGHTMEFLR
CHHHHHHHCCCCEEEECCHHHHHCCCCCCCEEHHCCEEEEEECCCCCCCCCCCCHHHHHH
EIAHLRPRTNTFGAVFRIRHNMAIAIHKFFHERGFFYFHTPIITASDCEGAGQMFQVTTK
HHHHCCCCCCCHHHHEEECCCHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEEHH
NLYDLKKDENGAIIYDDDFFGKQASLTVSGQLEGELAATALGAIYTFGPTFRAENSNTPR
HHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCHH
HLAEFWMIEPEVAFNDITDNMDLAEDFIKYCVQWALDNCYDDVKFLNDMFDKGLIERLQG
HHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKEEFVRLPYTEGIKILEEAVVKGHKFEFPVYWGVDLASEHERYLVEEHFKRPVILTDY
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEECC
PKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREADYDKLMTRIQELGIPMKDMWW
CHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHE
YLDTRKFGSCPHSGFGLGFERLLLFVTGMTNIRDVIPFPRTPRNAEF
EEECHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEKISRTKIVDLLKRRDFGAMVNVKGWVRTRRGSKQVNFIALNDGSTINNVQIVVDLANF
CCCCHHHHHHHHHHHCCCCCEEECHHHHEECCCCCEEEEEEECCCCCCCCEEEEEEHHCC
DEEMLKQITTGACISVNGELTESIGSGQAAEVQARGIEVLGTCDNTYPLQKKGHTMEFLR
CHHHHHHHCCCCEEEECCHHHHHCCCCCCCEEHHCCEEEEEECCCCCCCCCCCCHHHHHH
EIAHLRPRTNTFGAVFRIRHNMAIAIHKFFHERGFFYFHTPIITASDCEGAGQMFQVTTK
HHHHCCCCCCCHHHHEEECCCHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEEHH
NLYDLKKDENGAIIYDDDFFGKQASLTVSGQLEGELAATALGAIYTFGPTFRAENSNTPR
HHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCHH
HLAEFWMIEPEVAFNDITDNMDLAEDFIKYCVQWALDNCYDDVKFLNDMFDKGLIERLQG
HHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKEEFVRLPYTEGIKILEEAVVKGHKFEFPVYWGVDLASEHERYLVEEHFKRPVILTDY
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEECC
PKEIKAFYMKQNEDGKTVRAMDVLFPKIGEIIGGSEREADYDKLMTRIQELGIPMKDMWW
CHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHE
YLDTRKFGSCPHSGFGLGFERLLLFVTGMTNIRDVIPFPRTPRNAEF
EEECHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA