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The map label for this gene is yisQ [H]

Identifier: 150004184

GI number: 150004184

Start: 2110690

End: 2112039

Strand: Direct

Name: yisQ [H]

Synonym: BVU_1625

Alternate gene names: 150004184

Gene position: 2110690-2112039 (Clockwise)

Preceding gene: 150004182

Following gene: 150004185

Centisome position: 40.88

GC content: 43.33

Gene sequence:

>1350_bases
GTGGACGTAATTCAAGAACCGAGAAGTGTACGAAAGAACCTTGCCAGACTGGCGGTTCCTATTTTCATTGAAACATTGCT
GATTATGATGCTGGGCGCGGTAGATACCGTGATGCTGAGTCAGTATTCAGACAATAGTGTGGCTGCCGTCGGGGTGGTCA
ACCAGCTCATCATGTTTGCTTTCCTGATATTCGAGGTGATTAATATAGGAACTTCCGTACTCTGTTCGCAATATTTGGGA
GCAAGAATGCACAAGAATATGGTGCAGGTGGTGGGAGTATCATTGATACTCAATTTGGTGTTCGGCCTGTTTGTCAGTGC
TATTCTGCATTACGGAGCCACTTCTCTGCTATCTATGATGGGACTTCGTCCCGAACTGATGGAATATGGAGTGAGTTACA
TGAAGATAGTAGGGGCATTCGCTTTTTTTCAAGCCATATCTCTGACTATTTCTGCCTCTTTGCGTAGTGCTAACAAAGCG
GTTTATCCCATGATGGTAACGGTAGTTGTGAATATTCTGAATATCATCGGTAACTATTCGCTGATTTTCGGTAAGTTCGG
CATGCCGGCTTTGGGAGTGGAAGGTGCGGCTATCTCTACAGCATTTGCCCGAGGGGTATCTATGGTGATACTTTTTGTAA
TTCTTTTCCGCAAGCATATTCCCAGATTTCCGTTATCCTATTTTTGCCCCTTCCCGTTTGTCGAGCTGAAAAACCTGTTG
AAAATCGGAGTCCCCTCGGCCGGAGAAAATATGTCCTACAGTTTCTCTCAGGTAGTATTGACCTATTTTATTAATATGTT
GGGGAATGAAGCGCTGGCTACCCGTACCTATGTGGTGAATATAGTGATGTTCGTTTATTTGTTTGCTATTGCCATGGCAC
AAGGCGGAGCCATCTGTATCGGACATCTGGTAGGTGAAAGGAAAATTCATGCTGCCTATCTGTTAGGCAAATATGTGATG
CGTATTTCTATTTTGGTTTCTTTGGTTTTATCCTGTATCTGGGCTTTGATGGGGCATACCTTGTTTAGCTGGTTGACAGA
TAATCCGGAAATTATCCGTCTGGGTACTATTATCCTGTTTATTGATGTGATTTTGGAAGTGGGACGGGCTATTAATATTT
ATGCGACGAATGCTTTACGTGCAACGGGTGATGTAAATTATCCGTTTTATGTAGGATTTGTTGTTCAGTGGAGTGTTGCC
GTAGGTTGTGGTTTCTTGTTCGGCATTCATTGGGGATGGGGATTGGTAGGTATGTGGTGTGCGTTTGTGCTGGATGAAAA
TCTTCGTGGTATTATCTTTGTACAGCGTTGGAACAGTCTGAAATGGACTAAAAAGGGATTTGTGAAATAA

Upstream 100 bases:

>100_bases
TCTCCTTGTAAAAATCTTAAGTTCGTATTTCTTGATATAAATCAAACCGTTACATCGTGAAAAGTCTGTACCTTTGCACC
CCGAAAATCAAGGGTAACAA

Downstream 100 bases:

>100_bases
ATCTTCATTTTCGCAAACTTTATGCATCTTCAGGCCGTTAAACTCAAGAAAAAGAATTAATTTTGCAGTCTGATAATTAT
CAAAGAATATAATATGGAGC

Product: putative transmembrane transport efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MDVIQEPRSVRKNLARLAVPIFIETLLIMMLGAVDTVMLSQYSDNSVAAVGVVNQLIMFAFLIFEVINIGTSVLCSQYLG
ARMHKNMVQVVGVSLILNLVFGLFVSAILHYGATSLLSMMGLRPELMEYGVSYMKIVGAFAFFQAISLTISASLRSANKA
VYPMMVTVVVNILNIIGNYSLIFGKFGMPALGVEGAAISTAFARGVSMVILFVILFRKHIPRFPLSYFCPFPFVELKNLL
KIGVPSAGENMSYSFSQVVLTYFINMLGNEALATRTYVVNIVMFVYLFAIAMAQGGAICIGHLVGERKIHAAYLLGKYVM
RISILVSLVLSCIWALMGHTLFSWLTDNPEIIRLGTIILFIDVILEVGRAINIYATNALRATGDVNYPFYVGFVVQWSVA
VGCGFLFGIHWGWGLVGMWCAFVLDENLRGIIFVQRWNSLKWTKKGFVK

Sequences:

>Translated_449_residues
MDVIQEPRSVRKNLARLAVPIFIETLLIMMLGAVDTVMLSQYSDNSVAAVGVVNQLIMFAFLIFEVINIGTSVLCSQYLG
ARMHKNMVQVVGVSLILNLVFGLFVSAILHYGATSLLSMMGLRPELMEYGVSYMKIVGAFAFFQAISLTISASLRSANKA
VYPMMVTVVVNILNIIGNYSLIFGKFGMPALGVEGAAISTAFARGVSMVILFVILFRKHIPRFPLSYFCPFPFVELKNLL
KIGVPSAGENMSYSFSQVVLTYFINMLGNEALATRTYVVNIVMFVYLFAIAMAQGGAICIGHLVGERKIHAAYLLGKYVM
RISILVSLVLSCIWALMGHTLFSWLTDNPEIIRLGTIILFIDVILEVGRAINIYATNALRATGDVNYPFYVGFVVQWSVA
VGCGFLFGIHWGWGLVGMWCAFVLDENLRGIIFVQRWNSLKWTKKGFVK
>Mature_449_residues
MDVIQEPRSVRKNLARLAVPIFIETLLIMMLGAVDTVMLSQYSDNSVAAVGVVNQLIMFAFLIFEVINIGTSVLCSQYLG
ARMHKNMVQVVGVSLILNLVFGLFVSAILHYGATSLLSMMGLRPELMEYGVSYMKIVGAFAFFQAISLTISASLRSANKA
VYPMMVTVVVNILNIIGNYSLIFGKFGMPALGVEGAAISTAFARGVSMVILFVILFRKHIPRFPLSYFCPFPFVELKNLL
KIGVPSAGENMSYSFSQVVLTYFINMLGNEALATRTYVVNIVMFVYLFAIAMAQGGAICIGHLVGERKIHAAYLLGKYVM
RISILVSLVLSCIWALMGHTLFSWLTDNPEIIRLGTIILFIDVILEVGRAINIYATNALRATGDVNYPFYVGFVVQWSVA
VGCGFLFGIHWGWGLVGMWCAFVLDENLRGIIFVQRWNSLKWTKKGFVK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=439, Percent_Identity=23.4624145785877, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI48994890, Length=454, Percent_Identity=22.0264317180617, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49691; Mature: 49691

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVIQEPRSVRKNLARLAVPIFIETLLIMMLGAVDTVMLSQYSDNSVAAVGVVNQLIMFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLIFEVINIGTSVLCSQYLGARMHKNMVQVVGVSLILNLVFGLFVSAILHYGATSLLSMM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
GLRPELMEYGVSYMKIVGAFAFFQAISLTISASLRSANKAVYPMMVTVVVNILNIIGNYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
LIFGKFGMPALGVEGAAISTAFARGVSMVILFVILFRKHIPRFPLSYFCPFPFVELKNLL
HEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHH
KIGVPSAGENMSYSFSQVVLTYFINMLGNEALATRTYVVNIVMFVYLFAIAMAQGGAICI
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GHLVGERKIHAAYLLGKYVMRISILVSLVLSCIWALMGHTLFSWLTDNPEIIRLGTIILF
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
IDVILEVGRAINIYATNALRATGDVNYPFYVGFVVQWSVAVGCGFLFGIHWGWGLVGMWC
HHHHHHHCCEEEEEEECCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVLDENLRGIIFVQRWNSLKWTKKGFVK
HHHHHCCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MDVIQEPRSVRKNLARLAVPIFIETLLIMMLGAVDTVMLSQYSDNSVAAVGVVNQLIMFA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLIFEVINIGTSVLCSQYLGARMHKNMVQVVGVSLILNLVFGLFVSAILHYGATSLLSMM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
GLRPELMEYGVSYMKIVGAFAFFQAISLTISASLRSANKAVYPMMVTVVVNILNIIGNYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
LIFGKFGMPALGVEGAAISTAFARGVSMVILFVILFRKHIPRFPLSYFCPFPFVELKNLL
HEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHH
KIGVPSAGENMSYSFSQVVLTYFINMLGNEALATRTYVVNIVMFVYLFAIAMAQGGAICI
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GHLVGERKIHAAYLLGKYVMRISILVSLVLSCIWALMGHTLFSWLTDNPEIIRLGTIILF
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
IDVILEVGRAINIYATNALRATGDVNYPFYVGFVVQWSVAVGCGFLFGIHWGWGLVGMWC
HHHHHHHCCEEEEEEECCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVLDENLRGIIFVQRWNSLKWTKKGFVK
HHHHHCCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]