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The map label for this gene is mraY

Identifier: 150003966

GI number: 150003966

Start: 1873605

End: 1874873

Strand: Reverse

Name: mraY

Synonym: BVU_1400

Alternate gene names: 150003966

Gene position: 1874873-1873605 (Counterclockwise)

Preceding gene: 150003967

Following gene: 150003965

Centisome position: 36.31

GC content: 41.29

Gene sequence:

>1269_bases
ATGTTATATTATTTATTTCAATATTTAGAAAAGTTCGATTTTCCCGGAGCCGGTATGTTCGGTTACGTTTCATTCCGTTC
ATTGATGGCAATCATTTTATCATTGTTGATCTCAGCTATCTTCGGTGAATATTTCATCAACCTGCTCAAACGTAAACAAA
TAACCGAAACCCAACGTGACGCATCTATAGACCCTTTTAATGTGAAAAAAGTTGGTGTGCCGACGATGGGAGGTATAATT
ATTATTGTCGCAATTCTCATACCTTGCCTCTTGTTGGGGAAGCTGCATAATATTTACATGATATTAATGTTGATTACCAC
CATTTGGCTGGGTACGTTAGGCTTTTTGGACGACTATATCAAGGTCTTCCGTAAAGACAAAGAAGGGTTGCACGGCAAAT
TCAAGATCATCGGCCAAGTAGGTTTGGGACTCATTGTGGGACTCACCTTATATTTAAGTCCGAGCGTGGTTATCCGTGAG
AACGTAGAAATACAAAGAGGAGGAGAAATTGTGGAAGTGGTGCACAAGGAACAAGATCAGAAGTCCACCAAAACTACGAT
TCCTTTCTTCAAGAACAACAATTTGGATTATGCTGATTTCGTAGGTTTTCTGGGAAACAATGCCCAGGCTGTAGGTTGGA
TTATTTTCGTATTAGTTACCATCTTCGTAGTTACTGCCGTATCTAACGGTGCCAACCTGAATGACGGGATGGACGGGATG
GCAGCCGGAAATTCTGCTATCATCGGTCTTACCTTAGGCATATTGGCATACGTATCCAGCCACATCGAATATGCAGGATA
CCTTAATATCATGTACATTCCCGGCAGTGAAGAACTGGTAATCTTTATCTGCTCCTTCATCGGCGCACTGATCGGTTTCC
TTTGGTACAATGCTTTTCCCGCCCAAGTATTTATGGGCGATACCGGCAGCTTGACCATTGGTGGTATCATAGCGGTATTT
GCAATCATCATTCATAAAGAGTTGCTTATACCTATTCTCTGTGGAATCTTCTTGGTAGAAAACCTTTCGGTTATTCTACA
GGTGAGATATTTCAAAAGCGGAAAAAAGAAAGGACATTTGCAACGCGTATTCAAACGTGCCCCTATCCACGACCATTTCC
GCACTACATTAGCACAGTTAGACCCCAATTGCAGTTATCTGTTCATGAAACCCAACAGCGTATTCCATGAATCAAAAATC
ACGGTACGCTTCTGGATTGTCACCATCGTACTCGCTGCAATTACGATTATTACATTAAAGATAAGATAA

Upstream 100 bases:

>100_bases
AGGACACGAAAATTATCAGGAAATCAAAGGTATAAAGCACCATTTCGACGATAAAGAAGTATTAAGAGATATTTTTGCTA
ATGAATAAACCAACCAAAAG

Downstream 100 bases:

>100_bases
ACGAAGATTATGGCTAAAAGAATTGTCATACTAGGAGCCGGAGAAAGCGGTGCGGGAGCAGCCGTTCTGGCAAAGAAACA
AGGTTTCGACACCTTCGTTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLYYLFQYLEKFDFPGAGMFGYVSFRSLMAIILSLLISAIFGEYFINLLKRKQITETQRDASIDPFNVKKVGVPTMGGII
IIVAILIPCLLLGKLHNIYMILMLITTIWLGTLGFLDDYIKVFRKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPSVVIRE
NVEIQRGGEIVEVVHKEQDQKSTKTTIPFFKNNNLDYADFVGFLGNNAQAVGWIIFVLVTIFVVTAVSNGANLNDGMDGM
AAGNSAIIGLTLGILAYVSSHIEYAGYLNIMYIPGSEELVIFICSFIGALIGFLWYNAFPAQVFMGDTGSLTIGGIIAVF
AIIIHKELLIPILCGIFLVENLSVILQVRYFKSGKKKGHLQRVFKRAPIHDHFRTTLAQLDPNCSYLFMKPNSVFHESKI
TVRFWIVTIVLAAITIITLKIR

Sequences:

>Translated_422_residues
MLYYLFQYLEKFDFPGAGMFGYVSFRSLMAIILSLLISAIFGEYFINLLKRKQITETQRDASIDPFNVKKVGVPTMGGII
IIVAILIPCLLLGKLHNIYMILMLITTIWLGTLGFLDDYIKVFRKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPSVVIRE
NVEIQRGGEIVEVVHKEQDQKSTKTTIPFFKNNNLDYADFVGFLGNNAQAVGWIIFVLVTIFVVTAVSNGANLNDGMDGM
AAGNSAIIGLTLGILAYVSSHIEYAGYLNIMYIPGSEELVIFICSFIGALIGFLWYNAFPAQVFMGDTGSLTIGGIIAVF
AIIIHKELLIPILCGIFLVENLSVILQVRYFKSGKKKGHLQRVFKRAPIHDHFRTTLAQLDPNCSYLFMKPNSVFHESKI
TVRFWIVTIVLAAITIITLKIR
>Mature_422_residues
MLYYLFQYLEKFDFPGAGMFGYVSFRSLMAIILSLLISAIFGEYFINLLKRKQITETQRDASIDPFNVKKVGVPTMGGII
IIVAILIPCLLLGKLHNIYMILMLITTIWLGTLGFLDDYIKVFRKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPSVVIRE
NVEIQRGGEIVEVVHKEQDQKSTKTTIPFFKNNNLDYADFVGFLGNNAQAVGWIIFVLVTIFVVTAVSNGANLNDGMDGM
AAGNSAIIGLTLGILAYVSSHIEYAGYLNIMYIPGSEELVIFICSFIGALIGFLWYNAFPAQVFMGDTGSLTIGGIIAVF
AIIIHKELLIPILCGIFLVENLSVILQVRYFKSGKKKGHLQRVFKRAPIHDHFRTTLAQLDPNCSYLFMKPNSVFHESKI
TVRFWIVTIVLAAITIITLKIR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=422, Percent_Identity=33.4123222748815, Blast_Score=221, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BACV8 (A6L074)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298710.1
- STRING:   A6L074
- GeneID:   5302366
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1400
- NMPDR:   fig|435590.6.peg.1322
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 47027; Mature: 47027

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1af982cc)-; HASH(0x1b6227dc)-; HASH(0x1ad211fc)-; HASH(0x1bc3c7a8)-; HASH(0x1bd27780)-; HASH(0x1b94e270)-; HASH(0x1b8934bc)-; HASH(0x1ae7b558)-; HASH(0x1bdaddd8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYLFQYLEKFDFPGAGMFGYVSFRSLMAIILSLLISAIFGEYFINLLKRKQITETQRD
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASIDPFNVKKVGVPTMGGIIIIVAILIPCLLLGKLHNIYMILMLITTIWLGTLGFLDDYI
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVFRKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPSVVIRENVEIQRGGEIVEVVHKEQDQ
HHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCC
KSTKTTIPFFKNNNLDYADFVGFLGNNAQAVGWIIFVLVTIFVVTAVSNGANLNDGMDGM
CCCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AAGNSAIIGLTLGILAYVSSHIEYAGYLNIMYIPGSEELVIFICSFIGALIGFLWYNAFP
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
AQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGIFLVENLSVILQVRYFKSGKKKGHL
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QRVFKRAPIHDHFRTTLAQLDPNCSYLFMKPNSVFHESKITVRFWIVTIVLAAITIITLK
HHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEE
IR
EH
>Mature Secondary Structure
MLYYLFQYLEKFDFPGAGMFGYVSFRSLMAIILSLLISAIFGEYFINLLKRKQITETQRD
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASIDPFNVKKVGVPTMGGIIIIVAILIPCLLLGKLHNIYMILMLITTIWLGTLGFLDDYI
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVFRKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPSVVIRENVEIQRGGEIVEVVHKEQDQ
HHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCC
KSTKTTIPFFKNNNLDYADFVGFLGNNAQAVGWIIFVLVTIFVVTAVSNGANLNDGMDGM
CCCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AAGNSAIIGLTLGILAYVSSHIEYAGYLNIMYIPGSEELVIFICSFIGALIGFLWYNAFP
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
AQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGIFLVENLSVILQVRYFKSGKKKGHL
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QRVFKRAPIHDHFRTTLAQLDPNCSYLFMKPNSVFHESKITVRFWIVTIVLAAITIITLK
HHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEE
IR
EH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA