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The map label for this gene is uxuA [H]

Identifier: 150003830

GI number: 150003830

Start: 1692273

End: 1693448

Strand: Direct

Name: uxuA [H]

Synonym: BVU_1262

Alternate gene names: 150003830

Gene position: 1692273-1693448 (Clockwise)

Preceding gene: 150003829

Following gene: 150003831

Centisome position: 32.78

GC content: 45.41

Gene sequence:

>1176_bases
ATGATTTTATGTGAGCAAACATGGCGCTGGTACGGACCGAATGATCCCGTATCATTGTGGGACATCAAACAAGCCGGAGC
AACCGGTATTGTCAATGCCTTACATCATATTCCCAACGGTGAAGTATGGACGGTAGAGGAAATAATGAAGCGCAAGAAAT
TGATTGAAGAAGCAGGATTAACTTGGAGTGTCGTAGAATCCGTGCCCGTACACGAACATATTAAGACACAGACAGGAGAT
TATCTGAGATATATCGAGAACTATAAACAGAGTTTGCGTAATCTGGCAGCATGTGGTATCTATATTGTGACTTATAATTT
CATGCCTGTATTGGATTGGACCCGTACGGACCTGGCATATACGTTGCCCGATGGTTCCAAGGCATTGCGTTTTGAGCGGG
CTGCTTTTGTAGCGTTCGATCTGTTCATCTTGAAACGTCCGGGAGCCGAAAAGGAATACTCGGCCGAAGAGATAGAAAAG
GCAAAAGCGCGTCTGGCACAAATGGATGAGGAAGAAATTCATCGTCTGACACGAAATATGATTGCAGGATTGCCCGGTTC
GGAGGAAAGTTTTACATTGGAGCAATTCCAAAATGAACTGGACCGTTACAAGGATATTGATGCGGACAAACTCCGCAATA
ACTTGATTTTCTTCTTGAAAGAAATTTGTCCGGTAGCCGATGAAGTGGGAGTAAAGCTCGTTATTCATCCGGACGATCCG
CCTATGTCTATTCTGGGCTTGCCGCGCATTATGAGTACGGAGGCGGATTTCAAGCTGTTGGTGGAAGCTGTACCTAATCC
GTCAAACGGACTTTGTCTGTGCTGTGGCTCATTTGGCGTATCTGCACAGAATGATTTGCCGGGTATCATGGAACGTTGGG
GAGACCGTATCAATTTTGTTCATTTGCGCAGTACCCAACGTGATGCTGAAGGGAACTTTTATGAGGCGAATCATCTGGAG
GGTGATGTGGACATGTATCATGTAGTTAAGAACCTGTTGAAAGTGCAGCAACGTCGTGGAATATCTATTCCTATGCGTCC
GGATCATGGTCATCAGATGATAGATGATTTGAACAAGAAAACAAATCCGGGCTATTCTTGTTTGGGACGTATGCGTGGCC
TTGCCGAGCTTCGTGGTTTGGAAAAAGGAATAGCGATGAGTATGGTGGCAGAGTAA

Upstream 100 bases:

>100_bases
CAGCTTTGTAACCGGTACAGTAGCCGTAGTAGATGGTGGCTTCAATGCATTTGCCATGTAACAAGTCTTTAGTCTTTAAT
TCTCAATTTTTTTATTTGAT

Downstream 100 bases:

>100_bases
CTTCTTTTTAACATATAAAAATAAGACCTGAATGTCTTCCGGTATCCGGAGATCTTCAGGTCTTATTTTGTTTAAAGGCT
GGATAATAGGGGCTTTCTAG

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MILCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKKLIEEAGLTWSVVESVPVHEHIKTQTGD
YLRYIENYKQSLRNLAACGIYIVTYNFMPVLDWTRTDLAYTLPDGSKALRFERAAFVAFDLFILKRPGAEKEYSAEEIEK
AKARLAQMDEEEIHRLTRNMIAGLPGSEESFTLEQFQNELDRYKDIDADKLRNNLIFFLKEICPVADEVGVKLVIHPDDP
PMSILGLPRIMSTEADFKLLVEAVPNPSNGLCLCCGSFGVSAQNDLPGIMERWGDRINFVHLRSTQRDAEGNFYEANHLE
GDVDMYHVVKNLLKVQQRRGISIPMRPDHGHQMIDDLNKKTNPGYSCLGRMRGLAELRGLEKGIAMSMVAE

Sequences:

>Translated_391_residues
MILCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKKLIEEAGLTWSVVESVPVHEHIKTQTGD
YLRYIENYKQSLRNLAACGIYIVTYNFMPVLDWTRTDLAYTLPDGSKALRFERAAFVAFDLFILKRPGAEKEYSAEEIEK
AKARLAQMDEEEIHRLTRNMIAGLPGSEESFTLEQFQNELDRYKDIDADKLRNNLIFFLKEICPVADEVGVKLVIHPDDP
PMSILGLPRIMSTEADFKLLVEAVPNPSNGLCLCCGSFGVSAQNDLPGIMERWGDRINFVHLRSTQRDAEGNFYEANHLE
GDVDMYHVVKNLLKVQQRRGISIPMRPDHGHQMIDDLNKKTNPGYSCLGRMRGLAELRGLEKGIAMSMVAE
>Mature_391_residues
MILCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKKLIEEAGLTWSVVESVPVHEHIKTQTGD
YLRYIENYKQSLRNLAACGIYIVTYNFMPVLDWTRTDLAYTLPDGSKALRFERAAFVAFDLFILKRPGAEKEYSAEEIEK
AKARLAQMDEEEIHRLTRNMIAGLPGSEESFTLEQFQNELDRYKDIDADKLRNNLIFFLKEICPVADEVGVKLVIHPDDP
PMSILGLPRIMSTEADFKLLVEAVPNPSNGLCLCCGSFGVSAQNDLPGIMERWGDRINFVHLRSTQRDAEGNFYEANHLE
GDVDMYHVVKNLLKVQQRRGISIPMRPDHGHQMIDDLNKKTNPGYSCLGRMRGLAELRGLEKGIAMSMVAE

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=392, Percent_Identity=62.7551020408163, Blast_Score=522, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 44466; Mature: 44466

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKKLIEEAGL
CEEECCCCCCCCCCCCCEEEEHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
TWSVVESVPVHEHIKTQTGDYLRYIENYKQSLRNLAACGIYIVTYNFMPVLDWTRTDLAY
CEEHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCEECCCCCCCCEEE
TLPDGSKALRFERAAFVAFDLFILKRPGAEKEYSAEEIEKAKARLAQMDEEEIHRLTRNM
ECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IAGLPGSEESFTLEQFQNELDRYKDIDADKLRNNLIFFLKEICPVADEVGVKLVIHPDDP
HHCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCC
PMSILGLPRIMSTEADFKLLVEAVPNPSNGLCLCCGSFGVSAQNDLPGIMERWGDRINFV
CHHHHCCCHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCEEEE
HLRSTQRDAEGNFYEANHLEGDVDMYHVVKNLLKVQQRRGISIPMRPDHGHQMIDDLNKK
EEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCC
TNPGYSCLGRMRGLAELRGLEKGIAMSMVAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILCEQTWRWYGPNDPVSLWDIKQAGATGIVNALHHIPNGEVWTVEEIMKRKKLIEEAGL
CEEECCCCCCCCCCCCCEEEEHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
TWSVVESVPVHEHIKTQTGDYLRYIENYKQSLRNLAACGIYIVTYNFMPVLDWTRTDLAY
CEEHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCEECCCCCCCCEEE
TLPDGSKALRFERAAFVAFDLFILKRPGAEKEYSAEEIEKAKARLAQMDEEEIHRLTRNM
ECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IAGLPGSEESFTLEQFQNELDRYKDIDADKLRNNLIFFLKEICPVADEVGVKLVIHPDDP
HHCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCC
PMSILGLPRIMSTEADFKLLVEAVPNPSNGLCLCCGSFGVSAQNDLPGIMERWGDRINFV
CHHHHCCCHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCEEEE
HLRSTQRDAEGNFYEANHLEGDVDMYHVVKNLLKVQQRRGISIPMRPDHGHQMIDDLNKK
EEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCC
TNPGYSCLGRMRGLAELRGLEKGIAMSMVAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]