| Definition | Bacteroides vulgatus ATCC 8482 chromosome, complete genome. |
|---|---|
| Accession | NC_009614 |
| Length | 5,163,189 |
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The map label for this gene is uxuB [H]
Identifier: 150003829
GI number: 150003829
Start: 1691421
End: 1692233
Strand: Direct
Name: uxuB [H]
Synonym: BVU_1261
Alternate gene names: 150003829
Gene position: 1691421-1692233 (Clockwise)
Preceding gene: 150003828
Following gene: 150003830
Centisome position: 32.76
GC content: 45.88
Gene sequence:
>813_bases ATGAATAATTTGTTTAGTGTAAAAGACCAGGTGGTGGTAATCACCGGTGGAACAGGGGTTTTGGGAAAGGCTATTGCCGC CCATTTGGCAGAAGAAGGTGCCAAGGTTGTTATATTAGGTCGTAAGGCAGAAGTAGGAAATGCCATTGTAAACGAAATCA AGGCCAAAGGCGGGGAAGCCATGTTTCTTGTAACGAATGTGTTGGATGAGGCTATATTGGAGCAGAATCTGAAGGATATT CTCGCAGCATATGGTCGTGTAGATGCATTGCTGAATGCAGCAGGAGGTAATATGCCGGGTGCTACGATTGCTCCTACAGG AAATTTCTTTGATTTGAAAGTTGATGAGTTTCAGAAAGTGCTTAATCTGAATCTTACCGGAACCGTTCTGCCTACACAGG TATTTTTGAAGCCGATGGTGGAACAGAAGAAAGGGGCTATTGTGAACTTCTCTTCTATGGCGGCATTCCGTCCGATGACT CGTGTATGTGGTTATGCGGCTGCAAAGGCGGGAATCTCTAATTTCACTGCGTTCATGGCCAATGAAGTGGCTACGAAATT TGGTGAAGGCATCCGCGTGAATGCCATTGCTCCGGGATTCTTCCTGACCGAACAGAACCGTACTTTGTTGACAAACGAAG ATGGTACATATACTCAGCGTGGTAATGATGTGATTCGCCAGACTCCGTTCAAACGTTTCGGTAAAGCAGAGGAATTGTGT GGAACCATCCAGTATCTCATCAGCGATGCCAGCAGCTTTGTAACCGGTACAGTAGCCGTAGTAGATGGTGGCTTCAATGC ATTTGCCATGTAA
Upstream 100 bases:
>100_bases CCGAATTTGAGTATCGCCGATCTTTTGTTTAATATGGGGCCGGAGAGCCTGATTGTTTTGCGAGATAGTGTTAAAGGTAT AAACCATAAAGAATAATATC
Downstream 100 bases:
>100_bases CAAGTCTTTAGTCTTTAATTCTCAATTTTTTTATTTGATATGATTTTATGTGAGCAAACATGGCGCTGGTACGGACCGAA TGATCCCGTATCATTGTGGG
Product: D-mannonate oxidoreductase
Products: D-Gluconate; Nicotinamide adenine dinucleotide phosphate [C]
Alternate protein names: NA
Number of amino acids: Translated: 270; Mature: 270
Protein sequence:
>270_residues MNNLFSVKDQVVVITGGTGVLGKAIAAHLAEEGAKVVILGRKAEVGNAIVNEIKAKGGEAMFLVTNVLDEAILEQNLKDI LAAYGRVDALLNAAGGNMPGATIAPTGNFFDLKVDEFQKVLNLNLTGTVLPTQVFLKPMVEQKKGAIVNFSSMAAFRPMT RVCGYAAAKAGISNFTAFMANEVATKFGEGIRVNAIAPGFFLTEQNRTLLTNEDGTYTQRGNDVIRQTPFKRFGKAEELC GTIQYLISDASSFVTGTVAVVDGGFNAFAM
Sequences:
>Translated_270_residues MNNLFSVKDQVVVITGGTGVLGKAIAAHLAEEGAKVVILGRKAEVGNAIVNEIKAKGGEAMFLVTNVLDEAILEQNLKDI LAAYGRVDALLNAAGGNMPGATIAPTGNFFDLKVDEFQKVLNLNLTGTVLPTQVFLKPMVEQKKGAIVNFSSMAAFRPMT RVCGYAAAKAGISNFTAFMANEVATKFGEGIRVNAIAPGFFLTEQNRTLLTNEDGTYTQRGNDVIRQTPFKRFGKAEELC GTIQYLISDASSFVTGTVAVVDGGFNAFAM >Mature_270_residues MNNLFSVKDQVVVITGGTGVLGKAIAAHLAEEGAKVVILGRKAEVGNAIVNEIKAKGGEAMFLVTNVLDEAILEQNLKDI LAAYGRVDALLNAAGGNMPGATIAPTGNFFDLKVDEFQKVLNLNLTGTVLPTQVFLKPMVEQKKGAIVNFSSMAAFRPMT RVCGYAAAKAGISNFTAFMANEVATKFGEGIRVNAIAPGFFLTEQNRTLLTNEDGTYTQRGNDVIRQTPFKRFGKAEELC GTIQYLISDASSFVTGTVAVVDGGFNAFAM
Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=258, Percent_Identity=28.6821705426357, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=31.25, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI32483357, Length=265, Percent_Identity=27.5471698113208, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=29.3172690763052, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI4758504, Length=271, Percent_Identity=32.4723247232472, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=28.2945736434109, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI10190704, Length=259, Percent_Identity=27.4131274131274, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=26.4367816091954, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=31.4720812182741, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=28.1407035175879, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=29.7560975609756, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=26.7657992565056, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7705925, Length=265, Percent_Identity=26.0377358490566, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4503301, Length=239, Percent_Identity=27.6150627615063, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI20149619, Length=217, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI40254986, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI83715985, Length=271, Percent_Identity=29.8892988929889, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=27.1186440677966, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4504503, Length=209, Percent_Identity=31.1004784688995, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4557649, Length=219, Percent_Identity=27.8538812785388, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI226371731, Length=206, Percent_Identity=27.6699029126214, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI7705855, Length=198, Percent_Identity=29.2929292929293, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4503817, Length=206, Percent_Identity=29.126213592233, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1790717, Length=265, Percent_Identity=31.6981132075472, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=31.640625, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=30.1526717557252, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=29.277566539924, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=30.3846153846154, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=32.6923076923077, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.5882352941176, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=29.6153846153846, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367175, Length=267, Percent_Identity=31.4606741573034, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.1284046692607, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=26.3392857142857, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=26.0377358490566, Blast_Score=67, Evalue=9e-13, Organism=Caenorhabditis elegans, GI115534694, Length=263, Percent_Identity=27.3764258555133, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562910, Length=273, Percent_Identity=32.6007326007326, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=31.6602316602317, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.188679245283, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=25.0965250965251, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=28.735632183908, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=30.3030303030303, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=29.2418772563177, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.1317829457364, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17538480, Length=278, Percent_Identity=29.8561151079137, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=31.9702602230483, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561402, Length=268, Percent_Identity=25.7462686567164, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.9245283018868, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=28.7822878228782, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17538182, Length=278, Percent_Identity=30.2158273381295, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=30.2681992337165, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.0380228136882, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=28.8389513108614, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=247, Percent_Identity=29.9595141700405, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=29.4776119402985, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI72000259, Length=276, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=26.2172284644195, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560220, Length=199, Percent_Identity=30.1507537688442, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=27.1062271062271, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.5917602996255, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71997099, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=263, Percent_Identity=28.8973384030418, Blast_Score=84, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=35.1219512195122, Blast_Score=78, Evalue=1e-15, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=35.2490421455939, Blast_Score=139, Evalue=1e-33, Organism=Drosophila melanogaster, GI28571526, Length=267, Percent_Identity=32.5842696629214, Blast_Score=124, Evalue=7e-29, Organism=Drosophila melanogaster, GI21357041, Length=266, Percent_Identity=31.5789473684211, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=27.5193798449612, Blast_Score=101, Evalue=7e-22, Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=30.5343511450382, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=31.2977099236641, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=276, Percent_Identity=29.3478260869565, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=28.125, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21357673, Length=249, Percent_Identity=26.1044176706827, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24640492, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI24641232, Length=208, Percent_Identity=29.3269230769231, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21358495, Length=213, Percent_Identity=28.169014084507, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.69 [C]
Molecular weight: Translated: 28668; Mature: 28668
Theoretical pI: Translated: 7.27; Mature: 7.27
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNNLFSVKDQVVVITGGTGVLGKAIAAHLAEEGAKVVILGRKAEVGNAIVNEIKAKGGEA CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCE MFLVTNVLDEAILEQNLKDILAAYGRVDALLNAAGGNMPGATIAPTGNFFDLKVDEFQKV EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEECCHHHHHHH LNLNLTGTVLPTQVFLKPMVEQKKGAIVNFSSMAAFRPMTRVCGYAAAKAGISNFTAFMA HCCCCCCEECHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH NEVATKFGEGIRVNAIAPGFFLTEQNRTLLTNEDGTYTQRGNDVIRQTPFKRFGKAEELC HHHHHHHCCCEEEEEECCCEEEECCCCEEEECCCCCEECCCCHHHHCCCHHHHCCHHHHH GTIQYLISDASSFVTGTVAVVDGGFNAFAM HHHHHHHHHHHHHHEEEEEEEECCCHHCCC >Mature Secondary Structure MNNLFSVKDQVVVITGGTGVLGKAIAAHLAEEGAKVVILGRKAEVGNAIVNEIKAKGGEA CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCE MFLVTNVLDEAILEQNLKDILAAYGRVDALLNAAGGNMPGATIAPTGNFFDLKVDEFQKV EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEECCHHHHHHH LNLNLTGTVLPTQVFLKPMVEQKKGAIVNFSSMAAFRPMTRVCGYAAAKAGISNFTAFMA HCCCCCCEECHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH NEVATKFGEGIRVNAIAPGFFLTEQNRTLLTNEDGTYTQRGNDVIRQTPFKRFGKAEELC HHHHHHHCCCEEEEEECCCEEEECCCCEEEECCCCCEECCCCHHHHCCCHHHHCCHHHHH GTIQYLISDASSFVTGTVAVVDGGFNAFAM HHHHHHHHHHHHHHEEEEEEEECCCHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+; NADH; NADP+; NADPH [C]
Metal ions: Mn2+ [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 20 {D-gluconate}} 0.006 {NADPH}} 0.9 {5-keto-D-gluconate}} 0.02 {NADP+}} [C]
Substrates: 5-Dehydro-D-gluconate; H+; Nicotinamide adenine dinucleotide phosphate - reduced [C]
Specific reaction: 5-Dehydro-D-gluconate + H+ + Nicotinamide adenine dinucleotide phosphate - reduced <==> D-Gluconate + Nicotinamide adenine dinucleotide phosphate [C]
General reaction: Redox reaction [C]
Inhibitor: Cd2+; Cs2+; Cu2+; Divalent metal ions; Hg2+; Ni2+; p-Chloromercuribenzoate; Sn2+; Sulfhydryl reagents [C]
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9579062; 9384377 [H]