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The map label for this gene is upp [H]

Identifier: 150003550

GI number: 150003550

Start: 1291496

End: 1292155

Strand: Direct

Name: upp [H]

Synonym: BVU_0977

Alternate gene names: 150003550

Gene position: 1291496-1292155 (Clockwise)

Preceding gene: 150003547

Following gene: 150003554

Centisome position: 25.01

GC content: 46.67

Gene sequence:

>660_bases
ATGAAAATCATCAATCTCAGTGAAGGCAATTCTCTCCTAAACCAATATGTAGCGGAATTGCGCGATGTACATATTCAAAA
TGATCGTATGCGTTTCCGCAGAAATATTGAAAGAATAGGAGAAATCATGGCATACGAGATGAGTAAAGCACTAACCTATT
CCGTAAAGCAAGTACAGACACCCTTGGGAACTGCCACGGCCAGCACACACGATGACAAAATAGTGATCGCAACGGTATTC
CGTGCCGGACTGCCGCTGCACACCGGTTTTCTGAACATGTTCGACCATGCCGACAACGCTTTCGTTTCCGCATTCCGTTT
TTACAAAGATGATGAACACCGTATTGTAGATGTACACATTGAATACATCGCCGCTCCTTCATTGAATGACAGAACCTTGC
TTCTCGTTGATCCCATGCTTGCCACCGGTGAAAGCATGGAACTTGCCTGGAAAGCGTTCCTTACCAAAGGCAAACCAGCT
AAATTGCAGATGGCCTGTGTCATTGCCAGCCAACAAGGGGTAGCGCATATGGCAGAACTTTTTCCCGGCGATGATGTCAC
ATTATGGTGTGCCGCCATAGACCCTGTCTTGGACGAGCACAAATACATTGTTCCGGGGTTAGGGGATGCCGGTGATTTAT
CATTCGGCGAGAAACTCTAA

Upstream 100 bases:

>100_bases
ATTTATATTTGTGTAACAAAAATGCAATTCGTACTTTACAAATCTAGAAATTATTTGTTTCTTTGCAGGTCAAAGTCAAC
AATATAACAAAAGCATAGAT

Downstream 100 bases:

>100_bases
AGCTCAAACTATAAGGACAGTTTCAGGTGTGTTCTCTTACACACTAAAATTCTAAATTAAATGGTTAGTAACCGGCAATT
ATTCACTGCCTATTACTAAC

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKIINLSEGNSLLNQYVAELRDVHIQNDRMRFRRNIERIGEIMAYEMSKALTYSVKQVQTPLGTATASTHDDKIVIATVF
RAGLPLHTGFLNMFDHADNAFVSAFRFYKDDEHRIVDVHIEYIAAPSLNDRTLLLVDPMLATGESMELAWKAFLTKGKPA
KLQMACVIASQQGVAHMAELFPGDDVTLWCAAIDPVLDEHKYIVPGLGDAGDLSFGEKL

Sequences:

>Translated_219_residues
MKIINLSEGNSLLNQYVAELRDVHIQNDRMRFRRNIERIGEIMAYEMSKALTYSVKQVQTPLGTATASTHDDKIVIATVF
RAGLPLHTGFLNMFDHADNAFVSAFRFYKDDEHRIVDVHIEYIAAPSLNDRTLLLVDPMLATGESMELAWKAFLTKGKPA
KLQMACVIASQQGVAHMAELFPGDDVTLWCAAIDPVLDEHKYIVPGLGDAGDLSFGEKL
>Mature_219_residues
MKIINLSEGNSLLNQYVAELRDVHIQNDRMRFRRNIERIGEIMAYEMSKALTYSVKQVQTPLGTATASTHDDKIVIATVF
RAGLPLHTGFLNMFDHADNAFVSAFRFYKDDEHRIVDVHIEYIAAPSLNDRTLLLVDPMLATGESMELAWKAFLTKGKPA
KLQMACVIASQQGVAHMAELFPGDDVTLWCAAIDPVLDEHKYIVPGLGDAGDLSFGEKL

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Escherichia coli, GI87082118, Length=219, Percent_Identity=30.1369863013699, Blast_Score=94, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6321920, Length=141, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24423; Mature: 24423

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIINLSEGNSLLNQYVAELRDVHIQNDRMRFRRNIERIGEIMAYEMSKALTYSVKQVQT
CEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLGTATASTHDDKIVIATVFRAGLPLHTGFLNMFDHADNAFVSAFRFYKDDEHRIVDVHI
CCCCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEE
EYIAAPSLNDRTLLLVDPMLATGESMELAWKAFLTKGKPAKLQMACVIASQQGVAHMAEL
EEEECCCCCCCEEEEECCHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
FPGDDVTLWCAAIDPVLDEHKYIVPGLGDAGDLSFGEKL
CCCCCCEEEEEEHHHHHHCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIINLSEGNSLLNQYVAELRDVHIQNDRMRFRRNIERIGEIMAYEMSKALTYSVKQVQT
CEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLGTATASTHDDKIVIATVFRAGLPLHTGFLNMFDHADNAFVSAFRFYKDDEHRIVDVHI
CCCCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEE
EYIAAPSLNDRTLLLVDPMLATGESMELAWKAFLTKGKPAKLQMACVIASQQGVAHMAEL
EEEECCCCCCCEEEEECCHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
FPGDDVTLWCAAIDPVLDEHKYIVPGLGDAGDLSFGEKL
CCCCCCEEEEEEHHHHHHCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA