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The map label for this gene is typA [H]

Identifier: 150003547

GI number: 150003547

Start: 1287009

End: 1288811

Strand: Direct

Name: typA [H]

Synonym: BVU_0974

Alternate gene names: 150003547

Gene position: 1287009-1288811 (Clockwise)

Preceding gene: 150003546

Following gene: 150003550

Centisome position: 24.93

GC content: 43.54

Gene sequence:

>1803_bases
ATGCAAGACATTAGAAACATTGCGATCATCGCCCACGTAGACCACGGAAAAACGACTTTGGTGGACAAGATGATGCTGGC
GGGACATTTGTTCCGCAACGACCAGACAAATGGTGAACTGGTATTGGATAATAATGACTTGGAACGCGAAAGAGGGATAA
CTATCCTTTCAAAGAACGTTTCAATTAACTACAAAGGAACAAAAATCAATATTATTGATACTCCGGGACACGCCGACTTC
GGTGGCGAAGTAGAACGTGTACTCAATATGGCTGATGGATGTATCTTATTGGTAGACGCATTCGAAGGCCCGATGCCGCA
GACACGCTTCGTATTGCAAAAGGCATTACAGATCGGTTTGAAACCTGTAGTTGTAGTGAACAAGGTGGATAAACCCAACT
GCCGTCCGGAAGAAGTATACGAAATGGTATTCGACTTGATGTTCAGCCTGAATGCTACAGAAGATCAGTTGGATTTCCCC
GTTATCTATGGTTCTGCCAAAAATAATTGGATGAGTACTGATTGGAAGACCCCGACAGAAAACCTGGTTCCGTTGTTGGA
CGCTATTATTGAGCATATTCCGGCACCGAAGCAGTTGGAGGGAACTCCTCAAATGTTAATCACCTCTTTAGACTATTCAG
CATATACAGGTCGTATTGCTGTAGGACGTGTACATCGTGGTACGCTGAAAGAAGGTATGAATATTACACTAGCAAAGCGT
GATGGTAGTCTGATAAAGTCTAAAATCAAAGAGCTACATACTTTTGAAGGCTTAGGACGTAAAAAGACAAATGCCGTTTC
ATCGGGAGACATCTGTGCTGTAGTAGGTGTAGAAGGCTTCGAAATTGGTGATACTATCTGCGATTTCGAAAATCCGGAAC
CATTGCCCCCCATCGCCATTGACGAACCGACCATGAGTATGTTATTCACTATCAACGATTCTCCTTTCTTCGGCAAAGAA
GGTAAGTTTGTGACTTCACGCCACATCCAAGACCGCTTGACCAAAGAATTGGATAAGAACCTGGCATTGCGTGTACGCAA
AAGCGAACTGGAGGACGGTAAATGGATTGTTTCAGGACGTGGTGTGCTTCATCTTTCTGTCCTGATTGAAACCATGCGCC
GCGAAGGATACGAATTACAAGTGGGCCAGCCTCAGGTTATCTTCAAAGAAATAGACGGAGTAAAATGCGAACCTATCGAA
GAATTAACGATCAGCGTACCCGAAGAATATTCCAGTAAAATGATCGATATGGTAACCCGCCGTAAAGGTGATTTAGTTTC
TATGGAAACACAGGGTGACCGTGTAAACATTGAGTTTGATATGCCTTCGCGCGGTATTATCGGTCTTCGTACCAATGTAC
TGACAGCATCGGCCGGAGAAGCGATCATGGCTCACCGTTTTAAATGCTACCAACCATACAAGGGCGAGATAGAACGTCGC
AGCAACGGTTCTATGATTGCTATGGAAAGCGGAACAGCTTTTGCATACGCTATTGACAAATTACAGGATCGTGGCAAATT
TTTCATTTATCCGCAAGACGAAGTATATGCCGGCCAAGTAGTAGGTGAACATGTTCATGAAAACGACTTGGTTATCAATG
TAACTAAATCGAAGAAGCTTACCAATATGCGCGCATCAGGTTCTGATGACAAGGCACGCATCATTCCTCCGGTAGTATTT
TCGTTGGAAGAAGCATTGGAATACATTAAGGAAGATGAATATGTAGAAGTTACTCCAAAGAGTATGCGTATGCGTAAAGT
GATTCTTGACGAAACAGAACGTAAGAGAGCTAACAAAAGCTAA

Upstream 100 bases:

>100_bases
TAATAGTAAAGAAGATACGGAAGATAAAAAATAATCGTTAACAGCCAAATATTTTTTGAATTAAAAATCGTACCTTTGCA
GCCAAATATATAGGTATAGT

Downstream 100 bases:

>100_bases
TCAATCTACCTTTAATATAAAAAATCCCGGAGACCATATTATCTTCGGGATTTTTTATATTTAATCTACAAACTTTACTT
TACTAACTTCTCTAGGTTTA

Product: GTP-binding elongation factor family protein TypA/BipA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MQDIRNIAIIAHVDHGKTTLVDKMMLAGHLFRNDQTNGELVLDNNDLERERGITILSKNVSINYKGTKINIIDTPGHADF
GGEVERVLNMADGCILLVDAFEGPMPQTRFVLQKALQIGLKPVVVVNKVDKPNCRPEEVYEMVFDLMFSLNATEDQLDFP
VIYGSAKNNWMSTDWKTPTENLVPLLDAIIEHIPAPKQLEGTPQMLITSLDYSAYTGRIAVGRVHRGTLKEGMNITLAKR
DGSLIKSKIKELHTFEGLGRKKTNAVSSGDICAVVGVEGFEIGDTICDFENPEPLPPIAIDEPTMSMLFTINDSPFFGKE
GKFVTSRHIQDRLTKELDKNLALRVRKSELEDGKWIVSGRGVLHLSVLIETMRREGYELQVGQPQVIFKEIDGVKCEPIE
ELTISVPEEYSSKMIDMVTRRKGDLVSMETQGDRVNIEFDMPSRGIIGLRTNVLTASAGEAIMAHRFKCYQPYKGEIERR
SNGSMIAMESGTAFAYAIDKLQDRGKFFIYPQDEVYAGQVVGEHVHENDLVINVTKSKKLTNMRASGSDDKARIIPPVVF
SLEEALEYIKEDEYVEVTPKSMRMRKVILDETERKRANKS

Sequences:

>Translated_600_residues
MQDIRNIAIIAHVDHGKTTLVDKMMLAGHLFRNDQTNGELVLDNNDLERERGITILSKNVSINYKGTKINIIDTPGHADF
GGEVERVLNMADGCILLVDAFEGPMPQTRFVLQKALQIGLKPVVVVNKVDKPNCRPEEVYEMVFDLMFSLNATEDQLDFP
VIYGSAKNNWMSTDWKTPTENLVPLLDAIIEHIPAPKQLEGTPQMLITSLDYSAYTGRIAVGRVHRGTLKEGMNITLAKR
DGSLIKSKIKELHTFEGLGRKKTNAVSSGDICAVVGVEGFEIGDTICDFENPEPLPPIAIDEPTMSMLFTINDSPFFGKE
GKFVTSRHIQDRLTKELDKNLALRVRKSELEDGKWIVSGRGVLHLSVLIETMRREGYELQVGQPQVIFKEIDGVKCEPIE
ELTISVPEEYSSKMIDMVTRRKGDLVSMETQGDRVNIEFDMPSRGIIGLRTNVLTASAGEAIMAHRFKCYQPYKGEIERR
SNGSMIAMESGTAFAYAIDKLQDRGKFFIYPQDEVYAGQVVGEHVHENDLVINVTKSKKLTNMRASGSDDKARIIPPVVF
SLEEALEYIKEDEYVEVTPKSMRMRKVILDETERKRANKS
>Mature_600_residues
MQDIRNIAIIAHVDHGKTTLVDKMMLAGHLFRNDQTNGELVLDNNDLERERGITILSKNVSINYKGTKINIIDTPGHADF
GGEVERVLNMADGCILLVDAFEGPMPQTRFVLQKALQIGLKPVVVVNKVDKPNCRPEEVYEMVFDLMFSLNATEDQLDFP
VIYGSAKNNWMSTDWKTPTENLVPLLDAIIEHIPAPKQLEGTPQMLITSLDYSAYTGRIAVGRVHRGTLKEGMNITLAKR
DGSLIKSKIKELHTFEGLGRKKTNAVSSGDICAVVGVEGFEIGDTICDFENPEPLPPIAIDEPTMSMLFTINDSPFFGKE
GKFVTSRHIQDRLTKELDKNLALRVRKSELEDGKWIVSGRGVLHLSVLIETMRREGYELQVGQPQVIFKEIDGVKCEPIE
ELTISVPEEYSSKMIDMVTRRKGDLVSMETQGDRVNIEFDMPSRGIIGLRTNVLTASAGEAIMAHRFKCYQPYKGEIERR
SNGSMIAMESGTAFAYAIDKLQDRGKFFIYPQDEVYAGQVVGEHVHENDLVINVTKSKKLTNMRASGSDDKARIIPPVVF
SLEEALEYIKEDEYVEVTPKSMRMRKVILDETERKRANKS

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=431, Percent_Identity=29.4663573085847, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI94966754, Length=158, Percent_Identity=38.6075949367089, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI34147630, Length=238, Percent_Identity=36.1344537815126, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=36.551724137931, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI18390331, Length=140, Percent_Identity=39.2857142857143, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI19923640, Length=130, Percent_Identity=40, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25306287, Length=130, Percent_Identity=40, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25306283, Length=130, Percent_Identity=40, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI217272892, Length=134, Percent_Identity=36.5671641791045, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=36.5671641791045, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94966752, Length=154, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI53729339, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI53729337, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=50.5804311774461, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1788922, Length=506, Percent_Identity=27.8656126482213, Blast_Score=152, Evalue=9e-38,
Organism=Escherichia coli, GI1790412, Length=238, Percent_Identity=30.2521008403361, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789737, Length=238, Percent_Identity=30.2521008403361, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789738, Length=136, Percent_Identity=36.0294117647059, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=233, Percent_Identity=33.9055793991416, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17556745, Length=491, Percent_Identity=26.0692464358452, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=36.1538461538462, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=36.1538461538462, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=141, Percent_Identity=39.7163120567376, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17556456, Length=283, Percent_Identity=32.8621908127208, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17506493, Length=158, Percent_Identity=33.5443037974684, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=35.5555555555556, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25141371, Length=287, Percent_Identity=30.3135888501742, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994658, Length=230, Percent_Identity=30.8695652173913, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=491, Percent_Identity=28.9205702647658, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324761, Length=279, Percent_Identity=32.6164874551971, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324707, Length=204, Percent_Identity=34.8039215686275, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=204, Percent_Identity=34.8039215686275, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322359, Length=135, Percent_Identity=39.2592592592593, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6323098, Length=208, Percent_Identity=32.6923076923077, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=35, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI78706572, Length=527, Percent_Identity=26.3757115749526, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=42.4460431654676, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363316, Length=256, Percent_Identity=31.640625, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17864358, Length=256, Percent_Identity=31.640625, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24582462, Length=166, Percent_Identity=34.9397590361446, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585711, Length=150, Percent_Identity=34.6666666666667, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24585713, Length=150, Percent_Identity=34.6666666666667, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=34.6666666666667, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221458488, Length=160, Percent_Identity=38.75, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19921738, Length=294, Percent_Identity=28.9115646258503, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=35.8208955223881, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28572034, Length=231, Percent_Identity=29.004329004329, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67343; Mature: 67343

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00693 LUM_BINDING ; PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIRNIAIIAHVDHGKTTLVDKMMLAGHLFRNDQTNGELVLDNNDLERERGITILSKNV
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHCCCEEEEECE
SINYKGTKINIIDTPGHADFGGEVERVLNMADGCILLVDAFEGPMPQTRFVLQKALQIGL
EEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
KPVVVVNKVDKPNCRPEEVYEMVFDLMFSLNATEDQLDFPVIYGSAKNNWMSTDWKTPTE
CEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHH
NLVPLLDAIIEHIPAPKQLEGTPQMLITSLDYSAYTGRIAVGRVHRGTLKEGMNITLAKR
HHHHHHHHHHHHCCCCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCHHHCCCEEEEEEC
DGSLIKSKIKELHTFEGLGRKKTNAVSSGDICAVVGVEGFEIGDTICDFENPEPLPPIAI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCEEECCCCCCCCCCEEE
DEPTMSMLFTINDSPFFGKEGKFVTSRHIQDRLTKELDKNLALRVRKSELEDGKWIVSGR
CCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECC
GVLHLSVLIETMRREGYELQVGQPQVIFKEIDGVKCEPIEELTISVPEEYSSKMIDMVTR
CEEEHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCHHHHEEECCHHHHHHHHHHHHC
RKGDLVSMETQGDRVNIEFDMPSRGIIGLRTNVLTASAGEAIMAHRFKCYQPYKGEIERR
CCCCEEEEECCCCEEEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEC
SNGSMIAMESGTAFAYAIDKLQDRGKFFIYPQDEVYAGQVVGEHVHENDLVINVTKSKKL
CCCCEEEEECCCEEEEEHHHHHHCCCEEEEECCCCEECHHHHHHCCCCCEEEEEECCCCC
TNMRASGSDDKARIIPPVVFSLEEALEYIKEDEYVEVTPKSMRMRKVILDETERKRANKS
CCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MQDIRNIAIIAHVDHGKTTLVDKMMLAGHLFRNDQTNGELVLDNNDLERERGITILSKNV
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHCCCEEEEECE
SINYKGTKINIIDTPGHADFGGEVERVLNMADGCILLVDAFEGPMPQTRFVLQKALQIGL
EEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
KPVVVVNKVDKPNCRPEEVYEMVFDLMFSLNATEDQLDFPVIYGSAKNNWMSTDWKTPTE
CEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHH
NLVPLLDAIIEHIPAPKQLEGTPQMLITSLDYSAYTGRIAVGRVHRGTLKEGMNITLAKR
HHHHHHHHHHHHCCCCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCHHHCCCEEEEEEC
DGSLIKSKIKELHTFEGLGRKKTNAVSSGDICAVVGVEGFEIGDTICDFENPEPLPPIAI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCEEECCCCCCCCCCEEE
DEPTMSMLFTINDSPFFGKEGKFVTSRHIQDRLTKELDKNLALRVRKSELEDGKWIVSGR
CCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECC
GVLHLSVLIETMRREGYELQVGQPQVIFKEIDGVKCEPIEELTISVPEEYSSKMIDMVTR
CEEEHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCHHHHEEECCHHHHHHHHHHHHC
RKGDLVSMETQGDRVNIEFDMPSRGIIGLRTNVLTASAGEAIMAHRFKCYQPYKGEIERR
CCCCEEEEECCCCEEEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEC
SNGSMIAMESGTAFAYAIDKLQDRGKFFIYPQDEVYAGQVVGEHVHENDLVINVTKSKKL
CCCCEEEEECCCEEEEEHHHHHHCCCEEEEECCCCEECHHHHHHCCCCCEEEEEECCCCC
TNMRASGSDDKARIIPPVVFSLEEALEYIKEDEYVEVTPKSMRMRKVILDETERKRANKS
CCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]