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The map label for this gene is fusA [H]

Identifier: 150003389

GI number: 150003389

Start: 1101779

End: 1103896

Strand: Reverse

Name: fusA [H]

Synonym: BVU_0807

Alternate gene names: 150003389

Gene position: 1103896-1101779 (Counterclockwise)

Preceding gene: 150003390

Following gene: 150003388

Centisome position: 21.38

GC content: 42.49

Gene sequence:

>2118_bases
ATGGCTAAACATGATTTGCATTTGACCCGCAATATCGGTATCATGGCTCACATTGATGCTGGTAAGACAACGACTTCAGA
ACGTATTTTGTTCTACACTGGCTTGACTCACAAAATTGGTGAGGTGCATGATGGTGCAGCAACAATGGACTGGATGGAGC
AGGAGCAGGAACGTGGTATTACTATTACATCTGCTGCTACTACTACTCGTTGGAAATATGCGGGAAATACTTATAAAATA
AACTTGATTGACACTCCGGGACACGTTGACTTTACTGCTGAAGTAGAACGTTCTTTACGTGTCTTGGATGGAGCTGTTGC
AGCTTATTGTGCGGTTGGTGGTGTTGAACCTCAGTCAGAAACCGTATGGCGTCAGGCTGATAAATACAATGTGCCTCGTA
TTGGTTACGTTAATAAAATGGACCGTTCTGGTGCTGACTTTTTCGAAGTTGTTCGCCAGATGAAGGATGTATTAGGCGCA
AATGCTTGCCCTGTGGTAATTCCTATTGGTGCTGAAGAGAGCTTCAAAGGAGTTGTTGATTTGATTAAAATGAAAGCTAT
TTTGTGGCACGATGAAACAATGGGTGCAGATTATAGCGTAGAAGAAATTCCGGCGAACTTGGTTGATGAAGCTAATGAAT
GGAGAGAGAAAATGCTCGAAAAAGTGGCTGAATTTGACGATGCTTTAATGGAGAAATTCTTTGATGATCCTTCTACAATC
ACTGAAGAAGAAATCTTGCGTGCTTTGCGTGCAGGTACATTGAAAATGGATATCGTTCCGATGTTCTGCGGCTCTTCATT
CAAGAATAAGGGAGTTCAGACATTGCTTGACTATGTTTGTGCGTTCTTGCCTTCTCCGTTGGATACACCTGCTATTGTAG
GTACTAATCCGACTACAGGAGCAGAGGAAGACCGTAAACCTAGCGAGGATGAAAAAACATCAGCTTTGGCATTTAAGATT
GCAACTGACCCCTATGTCGGACGTTTGACTTTCTTCCGTGTTTACTCTGGTAAGGTAGAGGCTGGTTCATATATCTATAA
CACTCGTTCGGGTAAAAAAGAACGTGTATCACGTTTGTTCCAGATGCACTCAAACAAACAGAATCCTGTAGAGGTGATTG
GAGCTGGTGATATTGGTGCCGGTGTTGGTTTCAAGGATATCCGTACAGGTGATACGTTGTGTGATGAAGATGCACCGATC
GTATTGGAATCAATGGAATTCCCTGATCCTGTAATTGGTATTGCAGTTGAACCTAAGACTCAGAAAGATTTGGACAAGTT
GTCTAATGGCTTGGCTAAACTGGCTGAAGAAGACCCGACATTTACTGTTAAGACTGATGAGCAGTCCGGTCAGACTATTA
TTTCCGGTATGGGTGAGCTTCATTTGGATATTATTATCGACCGTCTGAAACGTGAGTTTAAAGTAGAATGTAACCAGGGT
AAACCTCAGGTTAACTATAAGGAAGCTATCACTAAGACTGTTGAATTGCGTGAAGTTTATAAGAAGCAGTCTGGTGGTCG
TGGTAAGTTTGCCGATATCATTGTGGCAATCGGCCCGGTTGATGAAGACTTTACACAAGGTGGTTTGCAGTTTATTGATG
AAGTGAAGGGCGGTAATGTTCCTAAGGAATTTATCCCATCAGTTCAGAAAGGTTTCCAGACCGCAATGAAGAATGGTGTG
TTGGCAGGGTATCCGCTTGATTCACTGAAAGTAGTTTTGAAGGATGGTTCATTCCATCCGGTTGACTCTGACCAGTTGTC
ATTCGAGATCTGTGCTATCCAGGCTTACAAAAATGCATGTGCTAAAGCAGGTCCTGTATTGACTGAACCTATTATGAAAC
TGGAGGTTGTAACTCCTGAAGAAAACATGGGTGATGTTATTGGTGACTTGAATAAGCGTCGTGGTCAAGTAGAAGGTATG
GAATCAAGCCGTTCTGGAGCTCGTATTGTAAAAGCTAAAGTACCTTTGGCAGAAATGTTTGGTTACGTAACAGCTTTGCG
TACTATTACTTCGGGCCGTGCTACATCATCTATGACTTATGATCATCATGCTCAAGTTTCCAGCTCTATTGCTAAGGCTG
TACTTGAAGAAGTGAAAGGTCGCGTAGACTTAGTATAA

Upstream 100 bases:

>100_bases
TATAAGCGTAAAGAAGATATGCACCGTATGGCTGAAGCTAACCGTGCATTCGCTCACTTTAGATTCTAATCAAGTAATAA
TTAATAAGTAAAGGACGAAG

Downstream 100 bases:

>100_bases
TAAAAAAAACAGGGGCGACGGGTTAGCGAATGACTCTTAATCCGGCCCCACTTTATATTTAATCATTTTTTAATTTAAAA
TTTAATGAGTCAAAAAATTA

Product: elongation factor G

Products: NA

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MAKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGITITSAATTTRWKYAGNTYKI
NLIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSETVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGA
NACPVVIPIGAEESFKGVVDLIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTI
TEEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTGAEEDRKPSEDEKTSALAFKI
ATDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLFQMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPI
VLESMEFPDPVIGIAVEPKTQKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQG
KPQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNVPKEFIPSVQKGFQTAMKNGV
LAGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNACAKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGM
ESSRSGARIVKAKVPLAEMFGYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV

Sequences:

>Translated_705_residues
MAKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGITITSAATTTRWKYAGNTYKI
NLIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSETVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGA
NACPVVIPIGAEESFKGVVDLIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTI
TEEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTGAEEDRKPSEDEKTSALAFKI
ATDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLFQMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPI
VLESMEFPDPVIGIAVEPKTQKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQG
KPQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNVPKEFIPSVQKGFQTAMKNGV
LAGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNACAKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGM
ESSRSGARIVKAKVPLAEMFGYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV
>Mature_704_residues
AKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGITITSAATTTRWKYAGNTYKIN
LIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSETVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGAN
ACPVVIPIGAEESFKGVVDLIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTIT
EEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTGAEEDRKPSEDEKTSALAFKIA
TDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLFQMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPIV
LESMEFPDPVIGIAVEPKTQKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQGK
PQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNVPKEFIPSVQKGFQTAMKNGVL
AGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNACAKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGME
SSRSGARIVKAKVPLAEMFGYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=701, Percent_Identity=44.5078459343795, Blast_Score=544, Evalue=1e-154,
Organism=Homo sapiens, GI19923640, Length=707, Percent_Identity=37.7652050919378, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI25306287, Length=703, Percent_Identity=34.9928876244666, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI25306283, Length=448, Percent_Identity=41.0714285714286, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI4503483, Length=421, Percent_Identity=28.2660332541568, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=40.6015037593985, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI157426893, Length=158, Percent_Identity=34.1772151898734, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI310132016, Length=117, Percent_Identity=40.1709401709402, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI310110807, Length=117, Percent_Identity=40.1709401709402, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI310123363, Length=117, Percent_Identity=40.1709401709402, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI94966752, Length=95, Percent_Identity=38.9473684210526, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI1789738, Length=694, Percent_Identity=58.2132564841499, Blast_Score=816, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=500, Percent_Identity=28.4, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1788922, Length=177, Percent_Identity=37.2881355932203, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI48994988, Length=175, Percent_Identity=37.1428571428571, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=685, Percent_Identity=40.2919708029197, Blast_Score=490, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17556745, Length=714, Percent_Identity=28.7114845938375, Blast_Score=288, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17506493, Length=819, Percent_Identity=26.984126984127, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17557151, Length=153, Percent_Identity=41.8300653594771, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=159, Percent_Identity=30.8176100628931, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988811, Length=159, Percent_Identity=30.8176100628931, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=698, Percent_Identity=41.1174785100287, Blast_Score=532, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6322359, Length=802, Percent_Identity=32.4189526184539, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6324707, Length=480, Percent_Identity=27.5, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320593, Length=480, Percent_Identity=27.5, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323320, Length=154, Percent_Identity=37.012987012987, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=150, Percent_Identity=34.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582462, Length=702, Percent_Identity=41.1680911680912, Blast_Score=519, Evalue=1e-147,
Organism=Drosophila melanogaster, GI221458488, Length=708, Percent_Identity=32.3446327683616, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24585711, Length=480, Percent_Identity=27.2916666666667, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24585713, Length=480, Percent_Identity=27.2916666666667, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24585709, Length=480, Percent_Identity=27.2916666666667, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI78706572, Length=150, Percent_Identity=36.6666666666667, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28574573, Length=138, Percent_Identity=38.4057971014493, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 77457; Mature: 77326

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGI
CCCCCEEEEECCCEEEEECCCCCCCCCEEEEEECCCHHHCCCCCCCHHHHHHHHHHHCCE
TITSAATTTRWKYAGNTYKINLIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSE
EEEECCCCEEEEECCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGANACPVVIPIGAEESFKGVVD
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
LIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTI
HHHHHHHHEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TEEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTG
CHHHHHHHHHCCCEEEEEEEHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCC
AEEDRKPSEDEKTSALAFKIATDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLF
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHH
QMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPIVLESMEFPDPVIGIAVEPKT
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCC
QKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQG
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHEEECCCC
KPQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
PKEFIPSVQKGFQTAMKNGVLAGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNAC
CHHHHHHHHHHHHHHHHCCCEECCCHHHHEEEEECCCCCCCCCCCCEEEEEEHHHHHHHH
AKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGMESSRSGARIVKAKVPLAEMF
HHCCCCHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHH
GYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGI
CCCCEEEEECCCEEEEECCCCCCCCCEEEEEECCCHHHCCCCCCCHHHHHHHHHHHCCE
TITSAATTTRWKYAGNTYKINLIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSE
EEEECCCCEEEEECCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGANACPVVIPIGAEESFKGVVD
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
LIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTI
HHHHHHHHEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TEEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTG
CHHHHHHHHHCCCEEEEEEEHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCC
AEEDRKPSEDEKTSALAFKIATDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLF
CCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHH
QMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPIVLESMEFPDPVIGIAVEPKT
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCC
QKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQG
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHEEECCCC
KPQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
PKEFIPSVQKGFQTAMKNGVLAGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNAC
CHHHHHHHHHHHHHHHHCCCEECCCHHHHEEEEECCCCCCCCCCCCEEEEEEHHHHHHHH
AKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGMESSRSGARIVKAKVPLAEMF
HHCCCCHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHH
GYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA