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The map label for this gene is truC [H]

Identifier: 149212744

GI number: 149212744

Start: 1523684

End: 1524232

Strand: Reverse

Name: truC [H]

Synonym: HI1435

Alternate gene names: 149212744

Gene position: 1524232-1523684 (Counterclockwise)

Preceding gene: 16273343

Following gene: 30995449

Centisome position: 83.29

GC content: 38.64

Gene sequence:

>549_bases
ATGCTAGAAATTTTATATCAAGATGGGTTTCTCGTTGCGGTGAATAAGCCTGCAGGTATGCTGGTTCATCGCAGTTGGTT
AGATCCTCACGAAACTCAATTTGTGATGCAAACTTTACGAGATCAGATTGGTCAGCACGTATTTCCTATTCATCGTTTAG
ATCGACCGACATCTGGCGTGTTGTTATTTGCATTGAGCAGTGAAATTGCGAATTTAATGTGTGAACAGTTTGAACAAAAG
TACGTTCAGAAATCTTATTTGGCTGTAGTGCGTGGGTATCTACAGGGAAAAGAGCGGATAGATTATCCACTAAAAATTCA
ATTGGATAAAATCGCAGATAAATTTTCTCAAGAAGATAAAGAGCCTCAAGAAGCGATTACTGATTATGAAGGATTAAAAA
TAGTCGAAATGCCTTATCCTGCTGGGCGTTATCAAACGGCGCGTTATTCTTTAGTTAAATTAATCCCTCATACAGGGCAG
AAAACACCAMTTACGTCGSCATATGAAACATGTTTTTCACCCAATTTKAGGGGATACGCAATATGGTGA

Upstream 100 bases:

>100_bases
CTATTTCTCCTTATATTGAAGAAGCAATGAAGGAATTTAATGAGTTACAACAACTATTAACTCCTTTAGTTGCTTTAGAA
GAACTTKTGAACAATAACGA

Downstream 100 bases:

>100_bases
CTTACATCAAAATCGTGCATTAATGTCACATTTAGGTTGTTCTCGATTATTTTTACATTCTGATAGTTTGTCTTTTATTC
ATCCAATAACGAAAGAGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA pseudouridylate synthase C; tRNA-uridine isomerase C [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MLEILYQDGFLVAVNKPAGMLVHRSWLDPHETQFVMQTLRDQIGQHVFPIHRLDRPTSGVLLFALSSEIANLMCEQFEQK
YVQKSYLAVVRGYLQGKERIDYPLKIQLDKIADKFSQEDKEPQEAITDYEGLKIVEMPYPAGRYQTARYSLVKLIPHTGQ
KTPJTSXYETCFSPNXRGYAIW

Sequences:

>Translated_182_residues
MLEILYQDGFLVAVNKPAGMLVHRSWLDPHETQFVMQTLRDQIGQHVFPIHRLDRPTSGVLLFALSSEIANLMCEQFEQK
YVQKSYLAVVRGYLQGKERIDYPLKIQLDKIADKFSQEDKEPQEAITDYEGLKIVEMPYPAGRYQTARYSLVKLIPHTGQ
KTPXTSXYETCFSPNXRGYAIW
>Mature_182_residues
MLEILYQDGFLVAVNKPAGMLVHRSWLDPHETQFVMQTLRDQIGQHVFPIHRLDRPTSGVLLFALSSEIANLMCEQFEQK
YVQKSYLAVVRGYLQGKERIDYPLKIQLDKIADKFSQEDKEPQEAITDYEGLKIVEMPYPAGRYQTARYSLVKLIPHTGQ
KTPXTSXYETCFSPNXRGYAIW

Specific function: Responsible for synthesis of pseudouridine from uracil- 65 in transfer RNAs [H]

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudouridine synthase rluA family [H]

Homologues:

Organism=Escherichia coli, GI1789155, Length=161, Percent_Identity=65.8385093167702, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006224
- InterPro:   IPR006145 [H]

Pfam domain/function: PF00849 PseudoU_synth_2 [H]

EC number: NA

Molecular weight: Translated: 20887; Mature: 20887

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS01129 PSI_RLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEILYQDGFLVAVNKPAGMLVHRSWLDPHETQFVMQTLRDQIGQHVFPIHRLDRPTSGV
CEEEEEECCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCE
LLFALSSEIANLMCEQFEQKYVQKSYLAVVRGYLQGKERIDYPLKIQLDKIADKFSQEDK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEHHHHHHHHHHCCC
EPQEAITDYEGLKIVEMPYPAGRYQTARYSLVKLIPHTGQKTPXTSXYETCFSPNXRGYA
CHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCEEE
IW
EC
>Mature Secondary Structure
MLEILYQDGFLVAVNKPAGMLVHRSWLDPHETQFVMQTLRDQIGQHVFPIHRLDRPTSGV
CEEEEEECCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCE
LLFALSSEIANLMCEQFEQKYVQKSYLAVVRGYLQGKERIDYPLKIQLDKIADKFSQEDK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEHHHHHHHHHHCCC
EPQEAITDYEGLKIVEMPYPAGRYQTARYSLVKLIPHTGQKTPXTSXYETCFSPNXRGYA
CHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCEEE
IW
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]