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The map label for this gene is sapA [H]

Identifier: 148828373

GI number: 148828373

Start: 1824873

End: 1826567

Strand: Reverse

Name: sapA [H]

Synonym: CGSHiGG_09890

Alternate gene names: 148828373

Gene position: 1826567-1824873 (Counterclockwise)

Preceding gene: 148828375

Following gene: 148828372

Centisome position: 96.79

GC content: 35.75

Gene sequence:

>1695_bases
ATGTTACGTCTAAATCTGAGATTTTTATCTTTTCTGCTCTATATAAGCCAAAGTGTAGAATTACAGGCTGCGCCAAGTGT
TCCAACATTTTTAACTGAAAACGGCTTAACTTATTGCACCCACGCTTCAGGTTTTTCATTTAATCCGCAAACGGCAGATG
CAGGAACCAGTATGAATGTGGTCACGGAACAAATTTATAACAAATTATTTGATATAAAAAATCACAGTGCAACATTAACA
CCAATGCTGGCACAATCTTATTCCATTTCAGCTGATGGTAAAGAAATTTTATTAAATTTACGTCACGGCGTAAAATTTCA
CCAAACCCCTTGGTTTACCCCAACACGTGATTTTAACGCTGAAGACGTAGTATTTTCGATTAATCGTGTATTAGGACATA
ATACTTATTTACCAACCTTAGCAGAGACGAATGTTACCTATAGTAATCCACAATATAGAGTGTTTCACGAACAAGCAAGA
AAAGTGCGTTTTCCTTATTTTGATAGCATTAAACTTAACGAAAAAATCAAATCTGTGACCGCACTTTCGCCTTATCAAGT
AAAAATTGAATTATTTGAGCCAGATTCCTCCATCTTGTCGCATCTTGCCAGCCAGTATGCCATTATTTTTTCACAAGAAT
ATGCCTATCAATTAAGCGCAGATGACAACCTTACTCAATTAGATACCCACCCAGTAGGCACAGGGCCTTATCAAGTAAAA
GATTATGTATATAACCAATATGTTCGCTTAGTGCGTAACGAAAACTATTGGAAAAAAGAAGCAAAAATTCAAAATATTAT
CGTGGATTTATCTACTGATAGAAACGGGCGACTCGTCAAATTTTTCAATAATGAATGTCAAATAGCCTCTTATCCTGAAG
TAAGCCAAATTGGCTTATTAAAGAGCAACGATAAGCACTACTATATGCAATCCACTGACGGAATGAATTTGGCATATCTT
GCCTTCAATTTTGAAAAGCCATTGATGCAGGATCGCACCATTCGAGAAGCTATCTCACAAAGTTTGAACCGTGCACGTAT
TATTCACAACATCTATCACAATACTGCGACAGTGGCGAATAACATTATTCCTGAAGTATCTTGGGCTTCAAGTGTCAATA
CGCCAGAATTTGAGTTTGATTACAATCCCAAAATCGCCAAAAATAAATTAGCAGATAAAAACCTTTTGTTAAATTTATGG
GTAATTAATGAAGAACAAGTCTATAATCCTGCACCTTTTAAAATGGCTGAAATGATAAAATGGGATTTAGCTCAAGCGGG
TGTGAAAGTTAAAGTGCGTGCCGTAACTCGTCCATTTTTAACTGCGCAATTACGCAATCAATCGGAAAATTATGATTTGA
TTCTATCTGGTTGGTTAGCTGGTAATCTTGATCCTGATGGTTTTATGCGTCCAATTTTAAGCTGTGGAACAAAAAATGAA
CTCACTAATTTATCTAATTGGTGTAATGAAGAATTTGATCAATTTATGGATCGCGCCATTACCACCTCACATTTAAGTTC
ACGCGCAAAATCCTATAATGAAGCCCAAGAACTCGTTTTACGTGAATTACCCATTATTCCTATTGCCAATGTAAAACGTA
TTTTAGTCGCAAATAGTCGTGTGAAAGGAGTAAAAATGACGCCTTTTGGTAGCTTAGATTTTTCCACTTTATATTTTATT
CAGGAGAAACACTAA

Upstream 100 bases:

>100_bases
GATTGATTTCCTTTTGAACCCGATTAAACATTCAATATCCTAGCCATTTTTACTAATATGCCTTACAATTTGACACATAA
TTTATCACAATGCATTTGTT

Downstream 100 bases:

>100_bases
TGTTATGGTCGGTTCTTCGCCATATTCTGTGGGTGGCATTATTATTACTCGTATTATCGCTATTAGGCTTTGTCATTTTA
TTACGCGATCCTCTTAATGC

Product: anti peptide resistance ABC transporter periplasmic protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MLRLNLRFLSFLLYISQSVELQAAPSVPTFLTENGLTYCTHASGFSFNPQTADAGTSMNVVTEQIYNKLFDIKNHSATLT
PMLAQSYSISADGKEILLNLRHGVKFHQTPWFTPTRDFNAEDVVFSINRVLGHNTYLPTLAETNVTYSNPQYRVFHEQAR
KVRFPYFDSIKLNEKIKSVTALSPYQVKIELFEPDSSILSHLASQYAIIFSQEYAYQLSADDNLTQLDTHPVGTGPYQVK
DYVYNQYVRLVRNENYWKKEAKIQNIIVDLSTDRNGRLVKFFNNECQIASYPEVSQIGLLKSNDKHYYMQSTDGMNLAYL
AFNFEKPLMQDRTIREAISQSLNRARIIHNIYHNTATVANNIIPEVSWASSVNTPEFEFDYNPKIAKNKLADKNLLLNLW
VINEEQVYNPAPFKMAEMIKWDLAQAGVKVKVRAVTRPFLTAQLRNQSENYDLILSGWLAGNLDPDGFMRPILSCGTKNE
LTNLSNWCNEEFDQFMDRAITTSHLSSRAKSYNEAQELVLRELPIIPIANVKRILVANSRVKGVKMTPFGSLDFSTLYFI
QEKH

Sequences:

>Translated_564_residues
MLRLNLRFLSFLLYISQSVELQAAPSVPTFLTENGLTYCTHASGFSFNPQTADAGTSMNVVTEQIYNKLFDIKNHSATLT
PMLAQSYSISADGKEILLNLRHGVKFHQTPWFTPTRDFNAEDVVFSINRVLGHNTYLPTLAETNVTYSNPQYRVFHEQAR
KVRFPYFDSIKLNEKIKSVTALSPYQVKIELFEPDSSILSHLASQYAIIFSQEYAYQLSADDNLTQLDTHPVGTGPYQVK
DYVYNQYVRLVRNENYWKKEAKIQNIIVDLSTDRNGRLVKFFNNECQIASYPEVSQIGLLKSNDKHYYMQSTDGMNLAYL
AFNFEKPLMQDRTIREAISQSLNRARIIHNIYHNTATVANNIIPEVSWASSVNTPEFEFDYNPKIAKNKLADKNLLLNLW
VINEEQVYNPAPFKMAEMIKWDLAQAGVKVKVRAVTRPFLTAQLRNQSENYDLILSGWLAGNLDPDGFMRPILSCGTKNE
LTNLSNWCNEEFDQFMDRAITTSHLSSRAKSYNEAQELVLRELPIIPIANVKRILVANSRVKGVKMTPFGSLDFSTLYFI
QEKH
>Mature_564_residues
MLRLNLRFLSFLLYISQSVELQAAPSVPTFLTENGLTYCTHASGFSFNPQTADAGTSMNVVTEQIYNKLFDIKNHSATLT
PMLAQSYSISADGKEILLNLRHGVKFHQTPWFTPTRDFNAEDVVFSINRVLGHNTYLPTLAETNVTYSNPQYRVFHEQAR
KVRFPYFDSIKLNEKIKSVTALSPYQVKIELFEPDSSILSHLASQYAIIFSQEYAYQLSADDNLTQLDTHPVGTGPYQVK
DYVYNQYVRLVRNENYWKKEAKIQNIIVDLSTDRNGRLVKFFNNECQIASYPEVSQIGLLKSNDKHYYMQSTDGMNLAYL
AFNFEKPLMQDRTIREAISQSLNRARIIHNIYHNTATVANNIIPEVSWASSVNTPEFEFDYNPKIAKNKLADKNLLLNLW
VINEEQVYNPAPFKMAEMIKWDLAQAGVKVKVRAVTRPFLTAQLRNQSENYDLILSGWLAGNLDPDGFMRPILSCGTKNE
LTNLSNWCNEEFDQFMDRAITTSHLSSRAKSYNEAQELVLRELPIIPIANVKRILVANSRVKGVKMTPFGSLDFSTLYFI
QEKH

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787551, Length=557, Percent_Identity=37.342908438061, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1789966, Length=561, Percent_Identity=29.2335115864528, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1787052, Length=491, Percent_Identity=23.0142566191446, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787762, Length=515, Percent_Identity=22.9126213592233, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1789887, Length=495, Percent_Identity=22.020202020202, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081878, Length=497, Percent_Identity=21.5291750503018, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64615; Mature: 64615

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLNLRFLSFLLYISQSVELQAAPSVPTFLTENGLTYCTHASGFSFNPQTADAGTSMNV
CEEEHHHHHHHHHHHHCCCEEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCHHH
VTEQIYNKLFDIKNHSATLTPMLAQSYSISADGKEILLNLRHGVKFHQTPWFTPTRDFNA
HHHHHHHHHHCCCCCCCEECHHHHCCEECCCCCHHHHHHHHCCCEECCCCCCCCCCCCCC
EDVVFSINRVLGHNTYLPTLAETNVTYSNPQYRVFHEQARKVRFPYFDSIKLNEKIKSVT
CHHHEEHHHHHCCCCCCCCCCCCCCEECCCCEEEEHHHHHEECCCCCCCEEHHHHHHHHH
ALSPYQVKIELFEPDSSILSHLASQYAIIFSQEYAYQLSADDNLTQLDTHPVGTGPYQVK
CCCCEEEEEEEECCCHHHHHHHHHHEEEEEEECEEEEECCCCCCEECCCCCCCCCCHHHH
DYVYNQYVRLVRNENYWKKEAKIQNIIVDLSTDRNGRLVKFFNNECQIASYPEVSQIGLL
HHHHHHHHHHHCCCCCHHHHHCEEEEEEEECCCCCCCEEEEECCCCEECCCCCHHHCCEE
KSNDKHYYMQSTDGMNLAYLAFNFEKPLMQDRTIREAISQSLNRARIIHNIYHNTATVAN
ECCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIIPEVSWASSVNTPEFEFDYNPKIAKNKLADKNLLLNLWVINEEQVYNPAPFKMAEMIK
HCCCCCCCCCCCCCCCEEECCCCCHHHHHCCCCCEEEEEEEECHHHCCCCCCHHHHHHHH
WDLAQAGVKVKVRAVTRPFLTAQLRNQSENYDLILSGWLAGNLDPDGFMRPILSCGTKNE
HHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCHH
LTNLSNWCNEEFDQFMDRAITTSHLSSRAKSYNEAQELVLRELPIIPIANVKRILVANSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
VKGVKMTPFGSLDFSTLYFIQEKH
CCCEEECCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MLRLNLRFLSFLLYISQSVELQAAPSVPTFLTENGLTYCTHASGFSFNPQTADAGTSMNV
CEEEHHHHHHHHHHHHCCCEEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCHHH
VTEQIYNKLFDIKNHSATLTPMLAQSYSISADGKEILLNLRHGVKFHQTPWFTPTRDFNA
HHHHHHHHHHCCCCCCCEECHHHHCCEECCCCCHHHHHHHHCCCEECCCCCCCCCCCCCC
EDVVFSINRVLGHNTYLPTLAETNVTYSNPQYRVFHEQARKVRFPYFDSIKLNEKIKSVT
CHHHEEHHHHHCCCCCCCCCCCCCCEECCCCEEEEHHHHHEECCCCCCCEEHHHHHHHHH
ALSPYQVKIELFEPDSSILSHLASQYAIIFSQEYAYQLSADDNLTQLDTHPVGTGPYQVK
CCCCEEEEEEEECCCHHHHHHHHHHEEEEEEECEEEEECCCCCCEECCCCCCCCCCHHHH
DYVYNQYVRLVRNENYWKKEAKIQNIIVDLSTDRNGRLVKFFNNECQIASYPEVSQIGLL
HHHHHHHHHHHCCCCCHHHHHCEEEEEEEECCCCCCCEEEEECCCCEECCCCCHHHCCEE
KSNDKHYYMQSTDGMNLAYLAFNFEKPLMQDRTIREAISQSLNRARIIHNIYHNTATVAN
ECCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIIPEVSWASSVNTPEFEFDYNPKIAKNKLADKNLLLNLWVINEEQVYNPAPFKMAEMIK
HCCCCCCCCCCCCCCCEEECCCCCHHHHHCCCCCEEEEEEEECHHHCCCCCCHHHHHHHH
WDLAQAGVKVKVRAVTRPFLTAQLRNQSENYDLILSGWLAGNLDPDGFMRPILSCGTKNE
HHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCHH
LTNLSNWCNEEFDQFMDRAITTSHLSSRAKSYNEAQELVLRELPIIPIANVKRILVANSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
VKGVKMTPFGSLDFSTLYFIQEKH
CCCEEECCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]