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The map label for this gene is mtnN [H]

Identifier: 148828364

GI number: 148828364

Start: 1812171

End: 1812860

Strand: Direct

Name: mtnN [H]

Synonym: CGSHiGG_09810

Alternate gene names: 148828364

Gene position: 1812171-1812860 (Clockwise)

Preceding gene: 148828363

Following gene: 148828366

Centisome position: 96.02

GC content: 41.45

Gene sequence:

>690_bases
ATGAAAATCGGAATTGTTGGTGCAATGGCACAAGAAGTCGAAATTTTAAAAAATTTAATGGCTGATAGAACGGAAACTCG
AGTAGCAAGTGCGGTCATTTTTGAAGGCAAAATTAACGGTAAAGATGTTGCATTATTGCAATCAGGCATTGGAAAAGTGG
CAGCTGCCATTGGCACGACGGCGTTATTGCAATTAGCCAAGCCAGATTGTGTGATCAATACTGGTTCTGCAGGTGGGGTA
GCAAAAGGCTTGAAAGTGGGGGATATTGTAATTTCTGATGAAACACGCTACCACGATGCAGACGTGACAGCTTTTGGCTA
TGAAAAAGGGCAGTTGCCTGCTAATCCTGCTGCATTTTTATCGGATAAAAAATTGGCAGATCTCGCTCAAGAAATTGCAG
AAAAGCAAGGACAATCAGTAAAACGTGGTTTAATTTGCTCTGGCGATAGTTTTATTAATAGCGAAGACAAAATTACACAA
ATTCAAGCAGATTTCCCAAATGTAATGGGCGTTGAAATGGAAGCCACAGCGATTGCACAAGTTTGTTATGCTTTTAATGT
GCCTTTTGTGGTGGTTCGTGCTATTTCTGATGGCGGCGATGGCAAAGCAAGTATGTCTTTTGAAGAGTTTTTGCCATTGG
CGGCGAAGCAGTCTTCGACATTAGTGTTAGGAATGATTGACAGACTGTAG

Upstream 100 bases:

>100_bases
GGGGAAAATATGTACTCACTGCGAGTACGCTTTATAACGATGATTATAGCGTTGCAGTGTTAGATTTTTTGGTAAATAAA
ATAGAACAGGAACAAAAACA

Downstream 100 bases:

>100_bases
TAATAATCTTTTAATAAGATAATAAATTCTAAAATTGAAGGCATAGCTATTAGCTATGCCTTTTATATGAACTCCCTAGA
ATTTATAGTTCAAACTCAGA

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVALLQSGIGKVAAAIGTTALLQLAKPDCVINTGSAGGV
AKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFLSDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKITQ
IQADFPNVMGVEMEATAIAQVCYAFNVPFVVVRAISDGGDGKASMSFEEFLPLAAKQSSTLVLGMIDRL

Sequences:

>Translated_229_residues
MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVALLQSGIGKVAAAIGTTALLQLAKPDCVINTGSAGGV
AKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFLSDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKITQ
IQADFPNVMGVEMEATAIAQVCYAFNVPFVVVRAISDGGDGKASMSFEEFLPLAAKQSSTLVLGMIDRL
>Mature_229_residues
MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVALLQSGIGKVAAAIGTTALLQLAKPDCVINTGSAGGV
AKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFLSDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKITQ
IQADFPNVMGVEMEATAIAQVCYAFNVPFVVVRAISDGGDGKASMSFEEFLPLAAKQSSTLVLGMIDRL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=229, Percent_Identity=56.7685589519651, Blast_Score=243, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24055; Mature: 24055

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVALLQSGIGKVAAAIGTT
CEEEEHHHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ALLQLAKPDCVINTGSAGGVAKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFL
HHHHHCCCCEEEECCCCCCHHCCCEECEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHH
SDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKITQIQADFPNVMGVEMEATAIAQ
CCHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCCCCCEEEEECCCCCEECCCHHHHHHHH
VCYAFNVPFVVVRAISDGGDGKASMSFEEFLPLAAKQSSTLVLGMIDRL
HHHHHCCCEEEEEEECCCCCCCCCCCHHHHHCHHCCCCCEEEEEECCCC
>Mature Secondary Structure
MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVALLQSGIGKVAAAIGTT
CEEEEHHHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ALLQLAKPDCVINTGSAGGVAKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFL
HHHHHCCCCEEEECCCCCCHHCCCEECEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHH
SDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKITQIQADFPNVMGVEMEATAIAQ
CCHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCCCCCEEEEECCCCCEECCCHHHHHHHH
VCYAFNVPFVVVRAISDGGDGKASMSFEEFLPLAAKQSSTLVLGMIDRL
HHHHHCCCEEEEEEECCCCCCCCCCCHHHHHCHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA