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The map label for this gene is sucC

Identifier: 148828346

GI number: 148828346

Start: 1790465

End: 1791649

Strand: Direct

Name: sucC

Synonym: CGSHiGG_09690

Alternate gene names: 148828346

Gene position: 1790465-1791649 (Clockwise)

Preceding gene: 148828345

Following gene: 148828348

Centisome position: 94.87

GC content: 41.27

Gene sequence:

>1185_bases
ATGAATTTACACGAATACCAAGCAAAACAACTATTTGAGCATTATGGATTACCCGTAAAAAATGGGGCAGTCTGTCAATC
TGTTGATGAGGTAGATTTGGTACTTGCTCAACTTTCAGGCGATAAGTGGGCAGCGAAATGCCAAGTTCATGCTGGTGGGC
GTGGTAAAGCGGGTGGCGTTAAATTGGTACAGGATGTAGAGGAAGCAAGATCTTTTGCAGAAAAATGGCTGGGACAACGT
TTAGTCACTTTTCAAACGGATAAATTGGGTCAGCCAGTAAACCAGATTTATTTTGAAGAAACTTGCGATATTGATAAAGA
ATTTTACTTAAGTGCGGTTGTTGATCGTGCCTCTCAAAAAGTGGTGTTTATTGCTTCTCCTGCAGGTGGAATGGATATTG
AAGAAGTTGCGCAAAATACACCGCACTTACTCCACAAAGTCGAGATTGATCCTTTATTTGGGGGATTGCCTTATCAAGGC
CGTGAATTGGCGTTTAAATTAGGGTTAAGTGATGCGCAAAACAAACAGTTTACCGATATCTTTATGGGCTTATCTCGTTT
GTTTTTAGAAAAAGATTTATCTTTAGTGGAAGTCAATCCGCTTGTTCTCACTCAACAAGGCAATTTGGTTTGTCTCGATG
CCAAAATAGCTGTCGATGATAACGCTTTATTTCGCCATAAAGATCTCTCAGCACTGCAAGATTTAACTCAAAATGATGCC
CGTGAAGCAGAAGCTGAAAAATTCCAGTTAAACTATGTGGCTTTAGAGGGCGATATTGGTTGTATGGTAAATGGGGCTGG
GCTTGCAATGGGTACCATGGATATTGTGAAACTCTATGGTGGGAAGCCTGCGAATTTTCTTGATGTGGGTGGTGGTGCAA
CGAAAGAGCGGGTTGCTGAAGCGTTCAAAATCATTTTAACCGATCCTTCCGTTAAAGTGATTTTAGTGAATATTTTTGGT
GGCATTGTTCGTTGTGATTTGATTGCTGAAGGTGTGATTGCTGCAGTAAATGAAGTGGGCGTGAGAGTGCCTGTGGTTGT
GCGATTAGAAGGAACCAATGCTGAAATCGGTCGCCAAATTTTAGCGGAAAGTGACGTTAATATTCTTACCGCACAGAGTT
TACAACAAGCTACAGAATTAGCCGTGAATGCAGCAAAGGAGAACTCTAATGGCGATTTTAATTGA

Upstream 100 bases:

>100_bases
TTCAAGCAAAACATTTATATCACGATCGTGAAGAAATCACGGTACATATAGCATTAAAACCTTGAGTGAATTGTTTTCAT
AACCAAAAAGGACGTCGCGA

Downstream 100 bases:

>100_bases
TAAAAATACTAAAGTGATTTGCCAAGGTTTTACTGGTGGACAAGGGGCTTTTCATTCCGAACAAGCATTAGCCTACGGAA
CGCAATTAGTTGGTGGCGTA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNLHEYQAKQLFEHYGLPVKNGAVCQSVDEVDLVLAQLSGDKWAAKCQVHAGGRGKAGGVKLVQDVEEARSFAEKWLGQR
LVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRASQKVVFIASPAGGMDIEEVAQNTPHLLHKVEIDPLFGGLPYQG
RELAFKLGLSDAQNKQFTDIFMGLSRLFLEKDLSLVEVNPLVLTQQGNLVCLDAKIAVDDNALFRHKDLSALQDLTQNDA
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATKERVAEAFKIILTDPSVKVILVNIFG
GIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEIGRQILAESDVNILTAQSLQQATELAVNAAKENSNGDFN

Sequences:

>Translated_394_residues
MNLHEYQAKQLFEHYGLPVKNGAVCQSVDEVDLVLAQLSGDKWAAKCQVHAGGRGKAGGVKLVQDVEEARSFAEKWLGQR
LVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRASQKVVFIASPAGGMDIEEVAQNTPHLLHKVEIDPLFGGLPYQG
RELAFKLGLSDAQNKQFTDIFMGLSRLFLEKDLSLVEVNPLVLTQQGNLVCLDAKIAVDDNALFRHKDLSALQDLTQNDA
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATKERVAEAFKIILTDPSVKVILVNIFG
GIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEIGRQILAESDVNILTAQSLQQATELAVNAAKENSNGDFN
>Mature_394_residues
MNLHEYQAKQLFEHYGLPVKNGAVCQSVDEVDLVLAQLSGDKWAAKCQVHAGGRGKAGGVKLVQDVEEARSFAEKWLGQR
LVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRASQKVVFIASPAGGMDIEEVAQNTPHLLHKVEIDPLFGGLPYQG
RELAFKLGLSDAQNKQFTDIFMGLSRLFLEKDLSLVEVNPLVLTQQGNLVCLDAKIAVDDNALFRHKDLSALQDLTQNDA
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATKERVAEAFKIILTDPSVKVILVNIFG
GIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEIGRQILAESDVNILTAQSLQQATELAVNAAKENSNGDFN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=42.5641025641026, Blast_Score=314, Evalue=8e-86,
Organism=Homo sapiens, GI157779135, Length=382, Percent_Identity=43.979057591623, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=44.7513812154696, Blast_Score=295, Evalue=4e-80,
Organism=Escherichia coli, GI1786948, Length=384, Percent_Identity=65.1041666666667, Blast_Score=505, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=41.75, Blast_Score=317, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=41.4948453608247, Blast_Score=294, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=40.8163265306122, Blast_Score=307, Evalue=2e-84,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=44.529262086514, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=44.529262086514, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=44.6700507614213, Blast_Score=314, Evalue=5e-86,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=44.6700507614213, Blast_Score=314, Evalue=5e-86,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=43.9393939393939, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_HAEIG (A5UIW0)

Other databases:

- EMBL:   CP000672
- RefSeq:   YP_001293099.1
- ProteinModelPortal:   A5UIW0
- SMR:   A5UIW0
- STRING:   A5UIW0
- GeneID:   5227763
- GenomeReviews:   CP000672_GR
- KEGG:   hiq:CGSHiGG_09690
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   EGDIGCM
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42745; Mature: 42745

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFEHYGLPVKNGAVCQSVDEVDLVLAQLSGDKWAAKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCH
KLVQDVEEARSFAEKWLGQRLVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRASQK
HHHHHHHHHHHHHHHHHCCEEEEEECHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
VVFIASPAGGMDIEEVAQNTPHLLHKVEIDPLFGGLPYQGRELAFKLGLSDAQNKQFTDI
EEEEECCCCCCCHHHHHCCCCHHEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHH
FMGLSRLFLEKDLSLVEVNPLVLTQQGNLVCLDAKIAVDDNALFRHKDLSALQDLTQNDA
HHHHHHHHHHCCCCEEEECCEEEEECCCEEEEEEEEEECCCCCEECCHHHHHHHHHHHHH
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILTDPSVKVILVNIFGGIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEIGRQI
HHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHH
LAESDVNILTAQSLQQATELAVNAAKENSNGDFN
HHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNLHEYQAKQLFEHYGLPVKNGAVCQSVDEVDLVLAQLSGDKWAAKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCH
KLVQDVEEARSFAEKWLGQRLVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRASQK
HHHHHHHHHHHHHHHHHCCEEEEEECHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
VVFIASPAGGMDIEEVAQNTPHLLHKVEIDPLFGGLPYQGRELAFKLGLSDAQNKQFTDI
EEEEECCCCCCCHHHHHCCCCHHEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHH
FMGLSRLFLEKDLSLVEVNPLVLTQQGNLVCLDAKIAVDDNALFRHKDLSALQDLTQNDA
HHHHHHHHHHCCCCEEEECCEEEEECCCEEEEEEEEEECCCCCEECCHHHHHHHHHHHHH
REAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILTDPSVKVILVNIFGGIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEIGRQI
HHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHH
LAESDVNILTAQSLQQATELAVNAAKENSNGDFN
HHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA