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The map label for this gene is coaA [H]

Identifier: 148827770

GI number: 148827770

Start: 1123861

End: 1124784

Strand: Direct

Name: coaA [H]

Synonym: CGSHiGG_06185

Alternate gene names: 148827770

Gene position: 1123861-1124784 (Clockwise)

Preceding gene: 148827769

Following gene: 148827785

Centisome position: 59.55

GC content: 33.01

Gene sequence:

>924_bases
ATGAATCTAACCCCTTTTTTAAGTTTTAACCGCAAACAATGGGCAGAATTGCGTAAATCTGTCCCCCTAAAACTTACAGA
ACAAGATCTTAAACCGCTTTTAGGTTTTAATGAAGAGCTATCTTTGGATGAAGTCAGTATGATTTATTTACCATTAGCTC
GTTTAATTAATTATTACATTGACGAAAACCTTCGCAGACAAGCTGTTTTACACCGTTTTTTAGGGCGTAATAAAACAAAA
GTACCTTATATCATTAGCATTGCAGGTAGCGTAGCGGTAGGGAAAAGCACTTCAGCACGAATACTCCAATCACTTCTTTC
CCATTGGCCAGCGGAGCGCAAAGTAGATCTTATAACTACTGATGGTTTTTTATATCCATTAGAAAAACTAAAAAAAGATC
ATCTTTTACACAAAAAAGGTTTCCCTATTTCTTATGATACGCCCAAACTTATTCATTTTTTAGCTGATGTGAAATCTGGC
AAAACTGAGGTGGAAGCACCAATCTATTCGCATTTAACCTATGATATTATTCCTGATAAATTTAATGTGATAAATAAACC
TGACATTCTTATTTTAGAGGGCTTGAATGTACTTCAAACGGGTAATAATAAAACCAATCAGACATTCGTATCAGATTTTG
TTGATTTCTCTATTTATGTTGATGCAGAAGAAAAATTATTGAAAGAATGGTATATCAAACGGTTTTTGAAATTCCGCGAA
AGCGCATTCAATGATCCTAATTCTTACTTTAAACATTATGCCAATTTATCGAAAGAAGAATCCATTACCACCGCTAGTAA
AATTTGGGATGAAATTAACGGGTTAAACCTTAATCAAAATATTCTTCCAACTCGTGAGCGAGCAAATCTAATTCTAAAAA
AAGGTCACAATCACCAAGTAGAATTAATAAAATTAAGAAAATAA

Upstream 100 bases:

>100_bases
TTAATCAAATTAGCGCACATTTAATGAAAAATGAATGCTAAATTTTTATTTATAGCGTATATTTTTCTCCAATTTGTCTA
TTTGACTCAATAATATCTCA

Downstream 100 bases:

>100_bases
AAATTCGCACGTAAAACGTGCGAATCTTAATTAATCCCTAACTCAAAATTAGTTATTGATAAAAATATCGTAAAAAATTA
CCGCACTTTTTATCGAAATT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNLTPFLSFNRKQWAELRKSVPLKLTEQDLKPLLGFNEELSLDEVSMIYLPLARLINYYIDENLRRQAVLHRFLGRNKTK
VPYIISIAGSVAVGKSTSARILQSLLSHWPAERKVDLITTDGFLYPLEKLKKDHLLHKKGFPISYDTPKLIHFLADVKSG
KTEVEAPIYSHLTYDIIPDKFNVINKPDILILEGLNVLQTGNNKTNQTFVSDFVDFSIYVDAEEKLLKEWYIKRFLKFRE
SAFNDPNSYFKHYANLSKEESITTASKIWDEINGLNLNQNILPTRERANLILKKGHNHQVELIKLRK

Sequences:

>Translated_307_residues
MNLTPFLSFNRKQWAELRKSVPLKLTEQDLKPLLGFNEELSLDEVSMIYLPLARLINYYIDENLRRQAVLHRFLGRNKTK
VPYIISIAGSVAVGKSTSARILQSLLSHWPAERKVDLITTDGFLYPLEKLKKDHLLHKKGFPISYDTPKLIHFLADVKSG
KTEVEAPIYSHLTYDIIPDKFNVINKPDILILEGLNVLQTGNNKTNQTFVSDFVDFSIYVDAEEKLLKEWYIKRFLKFRE
SAFNDPNSYFKHYANLSKEESITTASKIWDEINGLNLNQNILPTRERANLILKKGHNHQVELIKLRK
>Mature_307_residues
MNLTPFLSFNRKQWAELRKSVPLKLTEQDLKPLLGFNEELSLDEVSMIYLPLARLINYYIDENLRRQAVLHRFLGRNKTK
VPYIISIAGSVAVGKSTSARILQSLLSHWPAERKVDLITTDGFLYPLEKLKKDHLLHKKGFPISYDTPKLIHFLADVKSG
KTEVEAPIYSHLTYDIIPDKFNVINKPDILILEGLNVLQTGNNKTNQTFVSDFVDFSIYVDAEEKLLKEWYIKRFLKFRE
SAFNDPNSYFKHYANLSKEESITTASKIWDEINGLNLNQNILPTRERANLILKKGHNHQVELIKLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=63.6363636363636, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35612; Mature: 35612

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTPFLSFNRKQWAELRKSVPLKLTEQDLKPLLGFNEELSLDEVSMIYLPLARLINYYI
CCCCCCCCCCHHHHHHHHHCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DENLRRQAVLHRFLGRNKTKVPYIISIAGSVAVGKSTSARILQSLLSHWPAERKVDLITT
CCHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCEEEEEEC
DGFLYPLEKLKKDHLLHKKGFPISYDTPKLIHFLADVKSGKTEVEAPIYSHLTYDIIPDK
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCEEEECCCC
FNVINKPDILILEGLNVLQTGNNKTNQTFVSDFVDFSIYVDAEEKLLKEWYIKRFLKFRE
CCCCCCCCEEEECCCHHEECCCCCCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHH
SAFNDPNSYFKHYANLSKEESITTASKIWDEINGLNLNQNILPTRERANLILKKGHNHQV
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCEEEECCCCCCE
ELIKLRK
EEEEECC
>Mature Secondary Structure
MNLTPFLSFNRKQWAELRKSVPLKLTEQDLKPLLGFNEELSLDEVSMIYLPLARLINYYI
CCCCCCCCCCHHHHHHHHHCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DENLRRQAVLHRFLGRNKTKVPYIISIAGSVAVGKSTSARILQSLLSHWPAERKVDLITT
CCHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCEEEEEEC
DGFLYPLEKLKKDHLLHKKGFPISYDTPKLIHFLADVKSGKTEVEAPIYSHLTYDIIPDK
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCEEEECCCC
FNVINKPDILILEGLNVLQTGNNKTNQTFVSDFVDFSIYVDAEEKLLKEWYIKRFLKFRE
CCCCCCCCEEEECCCHHEECCCCCCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHH
SAFNDPNSYFKHYANLSKEESITTASKIWDEINGLNLNQNILPTRERANLILKKGHNHQV
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCEEEECCCCCCE
ELIKLRK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 7542800 [H]