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The map label for this gene is oxyR

Identifier: 148827763

GI number: 148827763

Start: 1117169

End: 1118074

Strand: Reverse

Name: oxyR

Synonym: CGSHiGG_06130

Alternate gene names: 148827763

Gene position: 1118074-1117169 (Counterclockwise)

Preceding gene: 148827765

Following gene: 148827762

Centisome position: 59.25

GC content: 40.18

Gene sequence:

>906_bases
ATGAATATCCGTGATCTAGAATATCTTGTTGCTTTATCTGAATATAAACATTTCCGCCGTGCTGCCGATTCTTGTAATGT
GAGCCAACCAACATTAAGTGGGCAAATTCGTAAGTTAGAAGATGAGCTTGGTATTATTTTGTTAGAACGTACTAGCCGTA
AAGTGTTGTTTACTCAATCTGGGATGTTATTGGTTGATCAGGCTCGCACAGTTCTTCGAGAAGTTAAATTATTGAAAGAA
ATGGCGAGTAATCAAGGTAAAGAAATGACCGGGCCATTACACATCGGTTTAATTCCAACGGTTGGTCCTTATTTGCTCCC
TTATATTGTGCCAATGTTAAAAGCGGCATTCCCTGATTTAGAAGTGTTTCTTTATGAAGCGCAAACGCATCAATTATTAG
AACAATTGGAAACGGGGCGTTTAGATTGTGCTATCGTTGCCACTGTTCCAGAAACTGAGGCTTTTATTGAAGTACCTATT
TTCAACGAGAAAATGTTACTCGCCGTATCAGAGCATCATCCTTGGGCTCAAGAAAGTAAACTTCCAATGAACCAATTAAA
TGGTCAAGAAATGTTAATGCTTGATGATGGTCATTGTTTGCGCAATCAAGCGCTAGATTATTGCTTCACTGCTGGTGCAA
AAGAAAATTCCCATTTCCAAGCAACTAGTCTTGAAACTTTGCGCAATATGGTAGCAGCCAATGCTGGTATCACTTTTATG
CCTGAATTGGCAGTACTGAATGAAGGTACGCGCAAAGGTGTGAAATATATTCCTTGTTATTCGCCAGAGCCATCACGCAC
CATTGCGTTGGTTTATCGTCCTGGTTCGCCATTACGTAATCGTTATGAGCGTGTGGCAAGTGCGGTCAGCGATGAAGTTA
AATCTATTCTAGATGGGTTGAAATAA

Upstream 100 bases:

>100_bases
TAATTTAAATTTTACGTGCTGCATTATAGGGAAAATTATGATATAGTCATAATCAATTAATTCTATTCTTTTAATTGAAT
TTTTCTATAGGGAAAATCTC

Downstream 100 bases:

>100_bases
TGGCTGGTGTTCGTGCTGTTCAAAAAGAAAAGACTCGTCGCGCTTTAGTGGATGCAGCATTTAATCAACTTAGCGCAGAA
AAAAGTTTTTCTAATTTAAG

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNIRDLEYLVALSEYKHFRRAADSCNVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQSGMLLVDQARTVLREVKLLKE
MASNQGKEMTGPLHIGLIPTVGPYLLPYIVPMLKAAFPDLEVFLYEAQTHQLLEQLETGRLDCAIVATVPETEAFIEVPI
FNEKMLLAVSEHHPWAQESKLPMNQLNGQEMLMLDDGHCLRNQALDYCFTAGAKENSHFQATSLETLRNMVAANAGITFM
PELAVLNEGTRKGVKYIPCYSPEPSRTIALVYRPGSPLRNRYERVASAVSDEVKSILDGLK

Sequences:

>Translated_301_residues
MNIRDLEYLVALSEYKHFRRAADSCNVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQSGMLLVDQARTVLREVKLLKE
MASNQGKEMTGPLHIGLIPTVGPYLLPYIVPMLKAAFPDLEVFLYEAQTHQLLEQLETGRLDCAIVATVPETEAFIEVPI
FNEKMLLAVSEHHPWAQESKLPMNQLNGQEMLMLDDGHCLRNQALDYCFTAGAKENSHFQATSLETLRNMVAANAGITFM
PELAVLNEGTRKGVKYIPCYSPEPSRTIALVYRPGSPLRNRYERVASAVSDEVKSILDGLK
>Mature_301_residues
MNIRDLEYLVALSEYKHFRRAADSCNVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQSGMLLVDQARTVLREVKLLKE
MASNQGKEMTGPLHIGLIPTVGPYLLPYIVPMLKAAFPDLEVFLYEAQTHQLLEQLETGRLDCAIVATVPETEAFIEVPI
FNEKMLLAVSEHHPWAQESKLPMNQLNGQEMLMLDDGHCLRNQALDYCFTAGAKENSHFQATSLETLRNMVAANAGITFM
PELAVLNEGTRKGVKYIPCYSPEPSRTIALVYRPGSPLRNRYERVASAVSDEVKSILDGLK

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790399, Length=298, Percent_Identity=71.1409395973154, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI157672245, Length=276, Percent_Identity=28.2608695652174, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788887, Length=283, Percent_Identity=29.6819787985866, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693105, Length=282, Percent_Identity=25.177304964539, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788748, Length=307, Percent_Identity=25.4071661237785, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790208, Length=276, Percent_Identity=28.6231884057971, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=26.6129032258064, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787879, Length=199, Percent_Identity=29.6482412060301, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=24.8995983935743, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367136, Length=246, Percent_Identity=26.0162601626016, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693193, Length=309, Percent_Identity=23.9482200647249, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789506, Length=125, Percent_Identity=30.4, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=25.8196721311475, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=26.2068965517241, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXYR_HAEIN (P44418)

Other databases:

- EMBL:   L42023
- EMBL:   U49355
- PIR:   C64078
- RefSeq:   NP_438728.1
- ProteinModelPortal:   P44418
- SMR:   P44418
- GeneID:   950698
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0571
- TIGR:   HI_0571
- HOGENOM:   HBG685425
- OMA:   ANEKSEF
- ProtClustDB:   PRK11151
- BioCyc:   HINF71421:HI_0571-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33762; Mature: 33762

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDLEYLVALSEYKHFRRAADSCNVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECC
GMLLVDQARTVLREVKLLKEMASNQGKEMTGPLHIGLIPTVGPYLLPYIVPMLKAAFPDL
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCC
EVFLYEAQTHQLLEQLETGRLDCAIVATVPETEAFIEVPIFNEKMLLAVSEHHPWAQESK
EEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCEEEEEEECCCCCCHHCC
LPMNQLNGQEMLMLDDGHCLRNQALDYCFTAGAKENSHFQATSLETLRNMVAANAGITFM
CCHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCEEC
PELAVLNEGTRKGVKYIPCYSPEPSRTIALVYRPGSPLRNRYERVASAVSDEVKSILDGL
CCHHHHCCCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure
MNIRDLEYLVALSEYKHFRRAADSCNVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECC
GMLLVDQARTVLREVKLLKEMASNQGKEMTGPLHIGLIPTVGPYLLPYIVPMLKAAFPDL
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCC
EVFLYEAQTHQLLEQLETGRLDCAIVATVPETEAFIEVPIFNEKMLLAVSEHHPWAQESK
EEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCEEEEEEECCCCCCHHCC
LPMNQLNGQEMLMLDDGHCLRNQALDYCFTAGAKENSHFQATSLETLRNMVAANAGITFM
CCHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCEEC
PELAVLNEGTRKGVKYIPCYSPEPSRTIALVYRPGSPLRNRYERVASAVSDEVKSILDGL
CCHHHHCCCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216