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The map label for this gene is cysQ [H]

Identifier: 148827751

GI number: 148827751

Start: 1103925

End: 1104734

Strand: Reverse

Name: cysQ [H]

Synonym: CGSHiGG_06070

Alternate gene names: 148827751

Gene position: 1104734-1103925 (Counterclockwise)

Preceding gene: 148827752

Following gene: 148827750

Centisome position: 58.54

GC content: 38.89

Gene sequence:

>810_bases
ATGCTGACGTTAAACGAACATTTACTTAATCAAGTATTGCTGATTGCTTATCAAGCGGGTAAGCATTTGCAACAGTTTTA
TCAAAAACAGGTTCATGTTGAATTGAAAGAAGACAACACGCCTGTGACGGAAGCGGATCTTTTTGTGAGCCAATTTTTAA
CCGAAAAATTGACCGCACTTTTCCCTAATGTCCCCGTTCTTTCGGAAGAAAATTGCCATATTTCCTTTGAAGAACGTAAA
AATTGGAAAGAATATTGGTTGATTGATCCTCTTGATGGCACACAACAATTTATTAATCGTACCGATCAATTTTCTGTGTT
GATAACCTTAGTTCGTAAAAATAAACCCGTGTTAAGTGTTATTCATGCGCCAATTTTATCGACAACTTATTATGCAATGG
ATAATTTCGGCGCATTTAAAAAACAACTGGATCAGGTAAAAAAACTCACTAAAAACACGACAAATTTTGACCGCCCTTTA
CGAATTGCGGTAGGTGCAACCACTTCACAAGAAAAAGTGCGGTCGATTTTGCCGAAGGATTTTCCTTGTGAATTTGTTGT
GGTTGGTTCAAGTAGCTTAAAAAGCGGTTTGGTGGCTGAAGGTGCAGTAGATAGTTATGTTCGTTTAGGACAAACAGGCG
AATGGGATACCGCTGGCGCTGAAGTGCTACTGGGTGAAACTCACGGTGCCATTTTTGACTCTCATTTTGAGCCTTTAACC
TATAACCAACGCGAAACATTGATTAATCCGCATTTTGTTATGGTGGGCGATCAATCGTTCGATTGGCGTTCTGTCTTTCA
ATTTAATTGA

Upstream 100 bases:

>100_bases
GAAGGGGGATTATCCCTCGGGTTAATAAGCACATGCGGAATGGTATTTTATGCTCTATTTGTAATGCCTTGGTTACTGCC
AAAAACAAGAGAATAATTTT

Downstream 100 bases:

>100_bases
TTGGTTCGATTGGTTTTTTTCTCTAGAATACGGCATTATTTTCGACATTACTCGGAAGCCGAATAAGGAATAATTATGCA
AACTGATAATAATTGTATCG

Product: 3'(2'),5'-bisphosphate nucleotidase CysQ

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTALFPNVPVLSEENCHISFEERK
NWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSVIHAPILSTTYYAMDNFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFPCEFVVVGSSSLKSGLVAEGAVDSYVRLGQTGEWDTAGAEVLLGETHGAIFDSHFEPLT
YNQRETLINPHFVMVGDQSFDWRSVFQFN

Sequences:

>Translated_269_residues
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTALFPNVPVLSEENCHISFEERK
NWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSVIHAPILSTTYYAMDNFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFPCEFVVVGSSSLKSGLVAEGAVDSYVRLGQTGEWDTAGAEVLLGETHGAIFDSHFEPLT
YNQRETLINPHFVMVGDQSFDWRSVFQFN
>Mature_269_residues
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTALFPNVPVLSEENCHISFEERK
NWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSVIHAPILSTTYYAMDNFGAFKKQLDQVKKLTKNTTNFDRPL
RIAVGATTSQEKVRSILPKDFPCEFVVVGSSSLKSGLVAEGAVDSYVRLGQTGEWDTAGAEVLLGETHGAIFDSHFEPLT
YNQRETLINPHFVMVGDQSFDWRSVFQFN

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=25.296442687747, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221625487, Length=253, Percent_Identity=25.296442687747, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790659, Length=247, Percent_Identity=35.6275303643725, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788882, Length=232, Percent_Identity=26.2931034482759, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193202572, Length=237, Percent_Identity=26.1603375527426, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193202570, Length=240, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24664918, Length=265, Percent_Identity=25.2830188679245, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30658; Mature: 30658

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
FPNVPVLSEENCHISFEERKNWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSV
CCCCCCCCCCCCEEEHHHHCCCCCEEEECCCCHHHHHHCCCCHHHEEEEEHHCCCCHHHH
IHAPILSTTYYAMDNFGAFKKQLDQVKKLTKNTTNFDRPLRIAVGATTSQEKVRSILPKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHCCCC
FPCEFVVVGSSSLKSGLVAEGAVDSYVRLGQTGEWDTAGAEVLLGETHGAIFDSHFEPLT
CCCCEEEECCCCHHCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCEECCCCCCCC
YNQRETLINPHFVMVGDQSFDWRSVFQFN
CCCHHHCCCCEEEEECCCCCCHHHHEECC
>Mature Secondary Structure
MLTLNEHLLNQVLLIAYQAGKHLQQFYQKQVHVELKEDNTPVTEADLFVSQFLTEKLTAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
FPNVPVLSEENCHISFEERKNWKEYWLIDPLDGTQQFINRTDQFSVLITLVRKNKPVLSV
CCCCCCCCCCCCEEEHHHHCCCCCEEEECCCCHHHHHHCCCCHHHEEEEEHHCCCCHHHH
IHAPILSTTYYAMDNFGAFKKQLDQVKKLTKNTTNFDRPLRIAVGATTSQEKVRSILPKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHCCCC
FPCEFVVVGSSSLKSGLVAEGAVDSYVRLGQTGEWDTAGAEVLLGETHGAIFDSHFEPLT
CCCCEEEECCCCHHCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCEECCCCCCCC
YNQRETLINPHFVMVGDQSFDWRSVFQFN
CCCHHHCCCCEEEEECCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]