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The map label for this gene is rbsK [H]

Identifier: 148827698

GI number: 148827698

Start: 1048183

End: 1049103

Strand: Direct

Name: rbsK [H]

Synonym: CGSHiGG_05785

Alternate gene names: 148827698

Gene position: 1048183-1049103 (Clockwise)

Preceding gene: 148827697

Following gene: 148827699

Centisome position: 55.54

GC content: 43.65

Gene sequence:

>921_bases
ATGAGAAAAACCCTCACGGTTCTCGGTAGTATCAATGCTGATCACGTTATTTCTGTGCCTTACTTTGCTAAACCCGGTGA
AACGCTAACAGGTCAAAATTATCAAATTGCCTATGGTGGCAAAGGTGCCAATCAAGCAGTGGCAGCCGCTCGTTTAGGGG
CAAAGGTCGCGTTCATTAGTTGCATTGGATCAGATAGCATAGGCAAAACAATGAAAAATGCGTTTGCACAAGAAGGAATT
GATACAACCCATATTAATACCGTTTCACAGGAAATGACGGGAATGGCATTTATTCAAGTTGCCCAATCGGGCGAGAACAG
TATTGTGCTGGCTAGCGGTGCAAATTCACATTTGAGTGAGACAGTTGTTCGTCAAAGTGAGGCGCAAATTGCACAATCGG
ATTGCTTGTTAATGCAATTAGAAACCCCACTTTCTGGTGTGGAGCTGGCTGCTCAAATCGCTAAGAAAAATGGTGTTAAG
GTTGTGCTAAATCCTGCTCCAGCGCAGATTTTATCGGACGAATTATTGAGTTTGATTGATATTATTACACCAAATGAAAC
TGAAGCTGAAATCCTGACGGCGGTAGCGGTAGCCGACGAGCAAAGTGCGGTGAAAGCTGCGAGTGTTTTTCACGATAAAG
GCATTGAAACCGTAATGATTACCCTTGGAGCGAAAGGTGTGTTTGTCAGTCGAAAAGGTAAAAGCCGCATCATTAAGGGC
TTTTGTGTGCAAGCAATAGATACTACCGCAGCTGGTGATACATTTAATGGCGGTTTTGTTACGGCTTTATTGGAAGAAAA
ATCCTTTGATGAAGCCATTCGTTTTGGTCAAGCTGCCGCTGCGATTAGTGTGACGAAAAAAGGGGCTCAATCCTCTATTC
CAACGCGGCAAGAAACTTTGGAATTTCTTGAACACGCTTAA

Upstream 100 bases:

>100_bases
TAATCTATCTACTAAATAAGCTCGTTATATCACATTATGGGGCAAATTATATTTGTCCCATTGTGTAGAAAGAAAAAATA
TAACAATACAGGATAAAATA

Downstream 100 bases:

>100_bases
AGTGCGGTGAATTTTTAGGGTGTTTTTATGGCGACAATGAAAGATATTGCACGACTGGCGCAAGTTTCGACTTCCACAGT
TTCACATGTCATTAATGGAT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRKTLTVLGSINADHVISVPYFAKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFISCIGSDSIGKTMKNAFAQEGI
DTTHINTVSQEMTGMAFIQVAQSGENSIVLASGANSHLSETVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVK
VVLNPAPAQILSDELLSLIDIITPNETEAEILTAVAVADEQSAVKAASVFHDKGIETVMITLGAKGVFVSRKGKSRIIKG
FCVQAIDTTAAGDTFNGGFVTALLEEKSFDEAIRFGQAAAAISVTKKGAQSSIPTRQETLEFLEHA

Sequences:

>Translated_306_residues
MRKTLTVLGSINADHVISVPYFAKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFISCIGSDSIGKTMKNAFAQEGI
DTTHINTVSQEMTGMAFIQVAQSGENSIVLASGANSHLSETVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVK
VVLNPAPAQILSDELLSLIDIITPNETEAEILTAVAVADEQSAVKAASVFHDKGIETVMITLGAKGVFVSRKGKSRIIKG
FCVQAIDTTAAGDTFNGGFVTALLEEKSFDEAIRFGQAAAAISVTKKGAQSSIPTRQETLEFLEHA
>Mature_306_residues
MRKTLTVLGSINADHVISVPYFAKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFISCIGSDSIGKTMKNAFAQEGI
DTTHINTVSQEMTGMAFIQVAQSGENSIVLASGANSHLSETVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVK
VVLNPAPAQILSDELLSLIDIITPNETEAEILTAVAVADEQSAVKAASVFHDKGIETVMITLGAKGVFVSRKGKSRIIKG
FCVQAIDTTAAGDTFNGGFVTALLEEKSFDEAIRFGQAAAAISVTKKGAQSSIPTRQETLEFLEHA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=37.1621621621622, Blast_Score=162, Evalue=5e-40,
Organism=Escherichia coli, GI1790193, Length=302, Percent_Identity=55.9602649006622, Blast_Score=320, Evalue=6e-89,
Organism=Escherichia coli, GI87081971, Length=282, Percent_Identity=30.4964539007092, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082343, Length=274, Percent_Identity=30.2919708029197, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788491, Length=259, Percent_Identity=25.8687258687259, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788484, Length=284, Percent_Identity=23.943661971831, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=311, Percent_Identity=38.5852090032154, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=28.1818181818182, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=36.6666666666667, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=30.6666666666667, Blast_Score=131, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32071; Mature: 32071

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTLTVLGSINADHVISVPYFAKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFIS
CCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEE
CIGSDSIGKTMKNAFAQEGIDTTHINTVSQEMTGMAFIQVAQSGENSIVLASGANSHLSE
EECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCCCHHHH
TVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVKVVLNPAPAQILSDELLSLID
HHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
IITPNETEAEILTAVAVADEQSAVKAASVFHDKGIETVMITLGAKGVFVSRKGKSRIIKG
HCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCHHHHHH
FCVQAIDTTAAGDTFNGGFVTALLEEKSFDEAIRFGQAAAAISVTKKGAQSSIPTRQETL
HHHHHHHCCCCCCCCCCCEEEEEEHHCCHHHHHHHCCHHHEEEEHHCCCCCCCCCHHHHH
EFLEHA
HHHHCC
>Mature Secondary Structure
MRKTLTVLGSINADHVISVPYFAKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFIS
CCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEE
CIGSDSIGKTMKNAFAQEGIDTTHINTVSQEMTGMAFIQVAQSGENSIVLASGANSHLSE
EECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCCCHHHH
TVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVKVVLNPAPAQILSDELLSLID
HHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHH
IITPNETEAEILTAVAVADEQSAVKAASVFHDKGIETVMITLGAKGVFVSRKGKSRIIKG
HCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCHHHHHH
FCVQAIDTTAAGDTFNGGFVTALLEEKSFDEAIRFGQAAAAISVTKKGAQSSIPTRQETL
HHHHHHHCCCCCCCCCCCEEEEEEHHCCHHHHHHHCCHHHEEEEHHCCCCCCCCCHHHHH
EFLEHA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]