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The map label for this gene is atpA [H]

Identifier: 148827677

GI number: 148827677

Start: 1028802

End: 1030343

Strand: Reverse

Name: atpA [H]

Synonym: CGSHiGG_05660

Alternate gene names: 148827677

Gene position: 1030343-1028802 (Counterclockwise)

Preceding gene: 148827678

Following gene: 148827676

Centisome position: 54.6

GC content: 39.88

Gene sequence:

>1542_bases
ATGCAACTAAATTCAACTGAAATTAGTGAATTGATTAAAAAACGCATCGCTCAATTTGACGTGGTGAGCGAAGCCCGTAA
TACAGGGACTATTGTTTCTGTAAGTGACGGGATTATTCGTATTCATGGCTTAAGCGATGTGATGCAAGGTGAAATGATCG
CCTTACCAGGTAATCGTTATGCGATGGCACTTAACCTTGAACGCGATTCTGTTGGTGCTGTAGTTATGGGACCTTACGCA
GATTTAGCGGAAGGTATGGAAGTTCAATGTACAGGTCGTATTCTTGAAGTACCAGTTGGTCGTGGTTTATTAGGTCGTGT
AGTTAATACGCTTGGTCAGCCAATCGATGGTAAAGGCGAAATTGACAATGATGGTTTCTCACCAGTAGAAGTGATTGCGC
CAGGTGTTATCGATCGTCGTTCTGTTGATCAACCTGTTCAAACTGGTTATAAAGCTGTCGATTCCATGGTACCGATTGGT
CGTGGTCAGCGTGAGTTAATCATCGGTGACCGTCAAACGGGTAAAACTGCGTTAGCAATTGACGCTATTATTAATCAACG
TAATTCAGGTATTAAATGTATCTATGTTGCGATTGGTCAAAAAGCCTCTACTATTGCAAACGTCGTGCGTAAATTAGAAG
AACATGGTGCGCTTGCAAATACTATCGTGGTAGCTGCATCTGCATCTGAATCAGCAGCGTTACAATATTTAGCCCCTTAT
GCTGGTTGTGCGATGGGGGAATATTTCCGTGATCGCGGCGAAGATGCGTTAATTGTTTATGATGATTTATCAAAACAAGC
CGTAGCTTATCGTCAAATTTCATTATTATTACGTCGTCCACCAGGTCGTGAAGCCTATCCAGGTGATGTGTTCTATTTAC
ATTCTCGTTTACTAGAACGTGCTTCTCGTGTAAATGAAGATTATGTAGAAAAATTCACTAAAGGCGAAGTAAAAGGAAAA
ACAGGTTCTTTAACCGCACTTCCTATTATTGAAACCCAAGCTGGTGACGTATCTGCGTTTGTTCCAACTAACGTAATTTC
TATTACCGATGGTCAGATCTTCTTAGAATCTAACTTGTTTAACTCAGGTATTCGTCCTGCGGTAAACCCAGGTATTTCGG
TATCTCGTGTTGGTGGTTCAGCACAAACTAAAGTTATTAAGAAATTAGCGGGTGGTATTCGTACCGCGCTAGCTCAATAT
CGTGAATTAGCAGCGTTTGCACAGTTTGCATCAGATCTAGATGATGCGACTCGTAAGCAACTTTCTCACGGTGAAAAAGT
AACTGAATTATTAAAACAAAAACAATTCGCGCCATTATCTGTTGCAGAACAAGCGGTTATATTGTTTGCTGTTGAATTTG
GTTATTTGGATGATGTGGAATTATCAAAAATTGCAAGTTTTGAGACCGCACTTTTAGATTATTCTAACCGTAATCACGCT
GAATTTATGCAAGAGCTTAATAAAACCGGTAACTATAATGATGAAATCAAAGATACGTTAAAAAGTATTTTAGATGGTTT
TAAAGCGAATAGTGCTTGGTAG

Upstream 100 bases:

>100_bases
AGGTGTGATTGTTCGTACTGAAGACTTTGTGATTGACGGAAGTAGCCGTGGGCAACTTACTCGTCTCGCAAACGAGTTGC
AATTATAAGAGGAATACAAG

Downstream 100 bases:

>100_bases
TAACGGAGAGATAAGATGGCAGGTGCAAAAGAGATAAAAACCAAAATTGCCAGTGTACAAAGTACACAAAAAATCACTAA
GGCAATGGAAATGGTGGCAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYA
DLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGEIDNDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVAASASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNEDYVEKFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQY
RELAAFAQFASDLDDATRKQLSHGEKVTELLKQKQFAPLSVAEQAVILFAVEFGYLDDVELSKIASFETALLDYSNRNHA
EFMQELNKTGNYNDEIKDTLKSILDGFKANSAW

Sequences:

>Translated_513_residues
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYA
DLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGEIDNDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVAASASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNEDYVEKFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQY
RELAAFAQFASDLDDATRKQLSHGEKVTELLKQKQFAPLSVAEQAVILFAVEFGYLDDVELSKIASFETALLDYSNRNHA
EFMQELNKTGNYNDEIKDTLKSILDGFKANSAW
>Mature_513_residues
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYA
DLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGEIDNDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIG
RGQRELIIGDRQTGKTALAIDAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVAASASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNEDYVEKFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQY
RELAAFAQFASDLDDATRKQLSHGEKVTELLKQKQFAPLSVAEQAVILFAVEFGYLDDVELSKIASFETALLDYSNRNHA
EFMQELNKTGNYNDEIKDTLKSILDGFKANSAW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=56.140350877193, Blast_Score=560, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=56.140350877193, Blast_Score=560, Evalue=1e-159,
Organism=Homo sapiens, GI32189394, Length=436, Percent_Identity=25, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913428, Length=315, Percent_Identity=27.3015873015873, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI19913426, Length=322, Percent_Identity=26.7080745341615, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=28.1368821292776, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=86.9395711500975, Blast_Score=928, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=384, Percent_Identity=25.5208333333333, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788251, Length=369, Percent_Identity=24.6612466124661, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.3689320388349, Blast_Score=548, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.3689320388349, Blast_Score=548, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=50.873786407767, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=26.0869565217391, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=313, Percent_Identity=27.7955271565495, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=440, Percent_Identity=23.6363636363636, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=27.0992366412214, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=63.8297872340426, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=55.5555555555556, Blast_Score=569, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6319603, Length=369, Percent_Identity=26.2872628726287, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=433, Percent_Identity=24.7113163972286, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658560, Length=511, Percent_Identity=54.4031311154599, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.4760383386581, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.4760383386581, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.4760383386581, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24638766, Length=397, Percent_Identity=25.4408060453401, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=26.1682242990654, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24583988, Length=263, Percent_Identity=28.5171102661597, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583986, Length=263, Percent_Identity=28.5171102661597, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583984, Length=263, Percent_Identity=28.5171102661597, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583992, Length=263, Percent_Identity=28.5171102661597, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129479, Length=258, Percent_Identity=28.2945736434109, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55548; Mature: 55548

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHCCCEEEECCCCE
AMALNLERDSVGAVVMGPYADLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGE
EEEEEECCCCCCEEEECCHHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
IDNDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAI
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVAASASESAALQYLAPY
HHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNEDYVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQYRELAAFAQFASDLDDATRKQ
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGEKVTELLKQKQFAPLSVAEQAVILFAVEFGYLDDVELSKIASFETALLDYSNRNHA
HHCCHHHHHHHHHHCCCCHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHH
EFMQELNKTGNYNDEIKDTLKSILDGFKANSAW
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQLNSTEISELIKKRIAQFDVVSEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHCCCEEEECCCCE
AMALNLERDSVGAVVMGPYADLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGE
EEEEEECCCCCCEEEECCHHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
IDNDGFSPVEVIAPGVIDRRSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAI
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQRNSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVAASASESAALQYLAPY
HHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNEDYVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NSGIRPAVNPGISVSRVGGSAQTKVIKKLAGGIRTALAQYRELAAFAQFASDLDDATRKQ
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGEKVTELLKQKQFAPLSVAEQAVILFAVEFGYLDDVELSKIASFETALLDYSNRNHA
HHCCHHHHHHHHHHCCCCHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHH
EFMQELNKTGNYNDEIKDTLKSILDGFKANSAW
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA