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The map label for this gene is folB [H]

Identifier: 148827421

GI number: 148827421

Start: 777768

End: 778124

Strand: Reverse

Name: folB [H]

Synonym: CGSHiGG_04115

Alternate gene names: 148827421

Gene position: 778124-777768 (Counterclockwise)

Preceding gene: 148827425

Following gene: 148827417

Centisome position: 41.23

GC content: 37.25

Gene sequence:

>357_bases
ATGGATCGTGTTTTTATTGAAGAATTGACTGTTTTTGCACAAATCGGTGTATATGATTGGGAACAGCAAATAAAACAAAA
ACTTGTGTTTGATTTAGAAATGGCTTGGGATTGTAAACAAGCGGCAGAAACGGATGATGTTGCATATTGTTTAAATTATG
CTGAAGTGAGCCAAGCGATTATTGATTATGTGGAAAGCAAACCTTTCTTGCTGATTGAGCGAGTGGCTTATGAAGTGGCG
GATTTGCTTGAGTCACGTTATCAACTTCAAGGATTAAAAATTAAGCTGAGTAAACCAAAAGCCGTCGCGCAAGCTCGAAA
TGTTGGCGTATTGATTGTTCGTGGTTGTTTAAAATAA

Upstream 100 bases:

>100_bases
AAGGGCGAAAAGGCTCATTTTGCACTCCAGCAAGAAAAACTGTTCGTTATTCTACCCAAAATTGATAGCATACGCCTACA
ATAATTTTAGAGGAAATCTT

Downstream 100 bases:

>100_bases
TGTAGCGATAGTGGCTATTAATAAATCTGACAGGCATGCAATTTAATTGGTGCCTGTCAGATTGGCTTTACACTTTTACC
TTGTGTTCTGAATAGTTATT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQAIIDYVESKPFLLIERVAYEVA
DLLESRYQLQGLKIKLSKPKAVAQARNVGVLIVRGCLK

Sequences:

>Translated_118_residues
MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQAIIDYVESKPFLLIERVAYEVA
DLLESRYQLQGLKIKLSKPKAVAQARNVGVLIVRGCLK
>Mature_118_residues
MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQAIIDYVESKPFLLIERVAYEVA
DLLESRYQLQGLKIKLSKPKAVAQARNVGVLIVRGCLK

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=115, Percent_Identity=60, Blast_Score=146, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13549; Mature: 13549

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQAI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHH
IDYVESKPFLLIERVAYEVADLLESRYQLQGLKIKLSKPKAVAQARNVGVLIVRGCLK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQAI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHH
IDYVESKPFLLIERVAYEVADLLESRYQLQGLKIKLSKPKAVAQARNVGVLIVRGCLK
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]