| Definition | Haemophilus influenzae PittGG chromosome, complete genome. |
|---|---|
| Accession | NC_009567 |
| Length | 1,887,192 |
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The map label for this gene is uvrA [H]
Identifier: 148827386
GI number: 148827386
Start: 735942
End: 738773
Strand: Reverse
Name: uvrA [H]
Synonym: CGSHiGG_03880
Alternate gene names: 148827386
Gene position: 738773-735942 (Counterclockwise)
Preceding gene: 148827390
Following gene: 148827385
Centisome position: 39.15
GC content: 41.31
Gene sequence:
>2832_bases ATGGAAAATATCGATATTCGCGGGGCTAGAACCCATAACCTGAAAAATATTAATTTAACTATTCCACGCAATAAACTTGT GGTGATTACTGGGCTTTCAGGTTCGGGAAAATCCTCTTTAGCCTTTGATACACTTTATGCGGAAGGGCAACGCAGCTATG TTGAATCTCTTTCGGCGTATGCACGCCAGTTTTTATCTTTAATGGAAAAGCCTGATGTGGATTCTATTGAGGGACTTTCC CCTGCAATTTCGATTGAACAAAAATCTACCTCACACAATCCACGTTCTACGGTGGGAACAATTACGGAAATTTATGATTA TTTACGTTTATTGTTTGCACGAGTAGGGGAGCCACGTTGTCCAGATCATGATGTTCCATTAACGGCACAAACGATTAGTC AAATGGTGGATAAAGTATTAAGTTTGCCAGAAGATAGCAAGATGATGTTACTTGCACCAGTTGTCAAAAATCGAAAAGGC GAACATCTCAAGATTTTAGAAAATATTGCTGCGCAAGGTTATATTCGTGCGCGTATTGATGGCGAAATTTGCGATTTATC TGATCCGCCAAAATTAGCCTTACAGAAAAAACATACTATTGAAGTAGTGGTTGATCGTTTTAAAGTGCGGTCAGATTTAG CAACACGTTTAGCCGAATCTTTTGAAACCGCATTAGAGCTTTCAGGTGGCACTGCGATTGTGGCAGATATGGATAATCCG AAAGCAGAAGAATTAGTTTTTTCGGCAAATTTTGCTTGTCCGCATTGTGGTTATTCTGTGCCAGAATTAGAGCCTCGTTT GTTTTCCTTTAACAATCCTGCAGGTGCTTGCCCAACTTGTGATGGCTTGGGTGTGCAGCAATATTTTGATGAAGATCGTG TGGTACAAAATCCAACTATTTCTCTTGCTGGTGGTGCGGTAAAAGGTTGGGATCGTCGTAATTTCTATTATTATCAAATG CTTACATCATTGGCGAAACATTATCATTTTGATGTTGAAGCCCCTTATGAATCTTTGCCAAAGAAAATTCAACACATCAT TATGCAGGGCTCAGGAAAAGAGGAAATTGAATTCCAATATATGAATGATCGTGGCGATGTGGTTATTCGCAAGCATCCTT TTGAAGGGATTTTGAATAATATGGCTCGCCGATATAAAGAAACGGAATCAATGTCGGTGCGTGAAGAATTAGCGAAAAAT ATTAGCAATCGACCTTGTATAGATTGTGGCGGCTCTCGTTTGCGACCCGAAGCGCGTAATGTGTATATTGGAAAAACCAA TTTGCCGATAATTGCGGAAAAAAGCATTGGCGAAACCCTTGAATTTTTTACCGCACTTTCTCTCACTGGTCAAAAAGCGC AAATTGCGGAAAAAATTCTTAAAGAAATCCGCGAGCGTTTGCAGTTTTTAGTCAATGTTGGTTTGAATTATCTTTCTCTT TCTCGTTCTGCTGAAACTCTTTCAGGTGGGGAGGCGCAACGTATTCGCCTTGCGAGTCAAATTGGTGCGGGACTTGTTGG CGTAATGTACGTATTAGATGAACCCTCTATTGGCTTGCACCAACGTGATAATGAACGCTTACTTAATACGTTAATTCATT TGCGTAATCTTGGTAATACGGTAATTGTCGTGGAGCACGATGAAGACGCGATTCGTGCAGCTGACCATATTATTGATATT GGGCCTGGTGCTGGCGTGCATGGCGGACAAGTTATTGCGCAAGGAAATGCCGATGAAATTATGCTCAATCCAAATTCCAT CACAGGAAAATTTTTATCGGGTGCAGATAAAATCGAAATCCCGAAAAAACGCACCGCACTTGATAAGAAAAAATGGCTCA AACTTAAAGGCGCATCAGGTAATAACTTAAAAAATGTGAATTTAGATATTCCCGTTGGTTTGTTTACTTGCGTAACTGGT GTGTCTGGTTCAGGAAAATCCACACTTATTAATGACACCTTATTTCCACTTGCGCAAAATGCGTTAAATAGAGCGGAAAA GACGGATTACGCACCTTATCAATCTATCGAGGGATTAGAACATTTCGATAAAGTTATTGATATTAACCAAAGCCCGATTG GGCGTACGCCACGTTCAAATCCAGCCACTTATACAGGCTTATTTACCCCAATTCGCGAGCTTTTTGCAGGGGTGCCAGAG GCACGTGCGCGCGGTTATAATCCTGGGCGTTTTAGCTTTAACGTACGAGGTGGACGCTGTGAAGCCTGTCAGGGCGATGG TGTACTCAAAGTTGAAATGCACTTTTTGCCTGATGTTTATGTTCCTTGCGATCAATGTAAAGGTAAACGCTATAATCGCG AAACCTTAGAAATTCGTTACAAAGGCAAAACGATTCATCAAGTTTTAGATATGACGGTGGAAGAAGCTCGCGAGTTTTTT GATGCGATTCCAATGATTGCAAGAAAATTACAAACCTTGATGGATGTGGGATTATCCTATATTCGATTAGGTCAATCTTC CACAACACTTTCAGGCGGCGAAGCACAACGCGTGAAACTAGCAACGGAACTTTCTAAACGTGATACGGGTAAAACTTTGT ATATTCTAGATGAACCGACGACTGGTTTGCATTTCGCTGACATTAAGCAATTACTTGAAGTATTGCATCGATTACGCGAT CAAGGAAATACTATCGTCGTCATTGAACACAATCTTGATGTGATTAAAACCGCAGACTGGATTGTCGATCTTGGCCCAGA GGGAGGCAGTGGCGGCGGACAAATTATTGCGACGGGTACACCAGAGCAAGTTGCCAAAGTAGAAAGTTCCCACACCGCTC GCTTCCTTAAACCGATTTTAGAAAAACCTTAG
Upstream 100 bases:
>100_bases TTAAAAGATCTATATATTTTAACTGGATATTTGCACAGATATTAAAATATGCGATAATGATCGCAAAATTTACATTTATT TCATACTTTTGAGTTATTTT
Downstream 100 bases:
>100_bases AAAAAATGACCGCACTTTCAGAGAAAACTCACATAAAGTGCGGTTATTTTATTAGTGATATTGTTTTAATTTTAGTTATC TGTATAAATTACATATAATA
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 943; Mature: 943
Protein sequence:
>943_residues MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRSYVESLSAYARQFLSLMEKPDVDSIEGLS PAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRCPDHDVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKG EHLKILENIAAQGYIRARIDGEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVADMDNP KAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTISLAGGAVKGWDRRNFYYYQM LTSLAKHYHFDVEAPYESLPKKIQHIIMQGSGKEEIEFQYMNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKN ISNRPCIDCGGSRLRPEARNVYIGKTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNTVIVVEHDEDAIRAADHIIDI GPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEIPKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTG VSGSGKSTLINDTLFPLAQNALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPE ARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFF DAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEQVAKVESSHTARFLKPILEKP
Sequences:
>Translated_943_residues MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRSYVESLSAYARQFLSLMEKPDVDSIEGLS PAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRCPDHDVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKG EHLKILENIAAQGYIRARIDGEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVADMDNP KAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTISLAGGAVKGWDRRNFYYYQM LTSLAKHYHFDVEAPYESLPKKIQHIIMQGSGKEEIEFQYMNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKN ISNRPCIDCGGSRLRPEARNVYIGKTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNTVIVVEHDEDAIRAADHIIDI GPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEIPKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTG VSGSGKSTLINDTLFPLAQNALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPE ARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFF DAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEQVAKVESSHTARFLKPILEKP >Mature_943_residues MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRSYVESLSAYARQFLSLMEKPDVDSIEGLS PAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRCPDHDVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKG EHLKILENIAAQGYIRARIDGEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVADMDNP KAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTISLAGGAVKGWDRRNFYYYQM LTSLAKHYHFDVEAPYESLPKKIQHIIMQGSGKEEIEFQYMNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKN ISNRPCIDCGGSRLRPEARNVYIGKTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNTVIVVEHDEDAIRAADHIIDI GPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEIPKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTG VSGSGKSTLINDTLFPLAQNALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPE ARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFF DAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEQVAKVESSHTARFLKPILEKP
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=81.5957446808511, Blast_Score=1602, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104291; Mature: 104291
Theoretical pI: Translated: 7.00; Mature: 7.00
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRSYVESLSAY CCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHCCHHHHHHHHHHH ARQFLSLMEKPDVDSIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRC HHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PDHDVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKGEHLKILENIAAQGYIRARID CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHCCEEEEEEC GEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVADMDNP CCEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCC KAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTI CHHHEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHCCCCCEECCCCE SLAGGAVKGWDRRNFYYYQMLTSLAKHYHFDVEAPYESLPKKIQHIIMQGSGKEEIEFQY EECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE MNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKNISNRPCIDCGGSRLRPEARN ECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE VYIGKTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSL EEEECCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEC SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNT CCCCHHCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE VIVVEHDEDAIRAADHIIDIGPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEI EEEEECCCHHHHHHHHEEECCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHCCCCCCCC PKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTGVSGSGKSTLINDTLFPLAQN CHHHHHCCHHHEEEEECCCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEECHHHHHHHHH ALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPE HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCH ARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRY HHHCCCCCCEEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEEEE KGKTIHQVLDMTVEEAREFFDAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCHHHHH ATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRDQGNTIVVIEHNLDVIKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCE IVDLGPEGGSGGGQIIATGTPEQVAKVESSHTARFLKPILEKP EEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRSYVESLSAY CCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHCCHHHHHHHHHHH ARQFLSLMEKPDVDSIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRC HHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PDHDVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKGEHLKILENIAAQGYIRARID CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHCCEEEEEEC GEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVADMDNP CCEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCC KAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTI CHHHEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHCCCCCEECCCCE SLAGGAVKGWDRRNFYYYQMLTSLAKHYHFDVEAPYESLPKKIQHIIMQGSGKEEIEFQY EECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE MNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKNISNRPCIDCGGSRLRPEARN ECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE VYIGKTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSL EEEECCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEC SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNT CCCCHHCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE VIVVEHDEDAIRAADHIIDIGPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEI EEEEECCCHHHHHHHHEEECCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHCCCCCCCC PKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTGVSGSGKSTLINDTLFPLAQN CHHHHHCCHHHEEEEECCCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEECHHHHHHHHH ALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPE HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCH ARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRY HHHCCCCCCEEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEEEE KGKTIHQVLDMTVEEAREFFDAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCHHHHH ATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRDQGNTIVVIEHNLDVIKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCE IVDLGPEGGSGGGQIIATGTPEQVAKVESSHTARFLKPILEKP EEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7542800; 8921840; 8063092 [H]