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The map label for this gene is aroK [H]

Identifier: 148827345

GI number: 148827345

Start: 679072

End: 679614

Strand: Direct

Name: aroK [H]

Synonym: CGSHiGG_03650

Alternate gene names: 148827345

Gene position: 679072-679614 (Clockwise)

Preceding gene: 148827344

Following gene: 148827346

Centisome position: 35.98

GC content: 38.49

Gene sequence:

>543_bases
ATGGCGGAAAAACGTAATATTTTTTTAGTAGGACCAATGGGTGCAGGTAAAAGTACTATCGGTCGTCAATTAGCACAACA
GCTTAATATGGATTTTATTGATTCCGATGCAGTGATTGAAGAACGTACGGGCGCGGATATTAGCTGGATTTTTGATTTGG
AAGGCGAAGACGGCTTCCGAAAACGTGAAGAACGCATTATTAACGAACTCACACAAATGCAAGGTATTGTCCTTTCAACT
GGTGGTGGTGCAGTGCTTTCTAAGGAAAACCGTAATTATTTATCAGCACGTGGTATTGTGATTTATTTAGAAACAACGGT
GGAAAAACAATTCCAACGCACTCAACGTGATAAAAAACGTCCATTGCTCCAAGATGCAGAGAATCCTCGCCAAGTATTGG
AAGATTTAGCAAAAATTCGCAATCCGCTTTATGAAGAAATTGCGGACATCACTTTGCCAACCGATGAACAAAATGCCAAA
ATAATGGTAAATCAAATTGTTGATTTAATTGATAATATGAATGGGTTGAATGGTGCACTTTAA

Upstream 100 bases:

>100_bases
TTTTTGGGAGATCTTTCTATCTTCTGCATTTTTACGCAGTTTATTTTCATTAGAAATGATCGAATTTTATTTCACTTTTA
ATTTAATTAGATAAAGAACA

Downstream 100 bases:

>100_bases
ACACACCTAAGGATAAATTATGCTGTGCGTCAACGTGGAATTGCAAGAGCGTCGCTATCCTATTTTAATTGGTAGCGGAT
TGTTACAAGATGAACGTAGT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMDFIDSDAVIEERTGADISWIFDLEGEDGFRKREERIINELTQMQGIVLST
GGGAVLSKENRNYLSARGIVIYLETTVEKQFQRTQRDKKRPLLQDAENPRQVLEDLAKIRNPLYEEIADITLPTDEQNAK
IMVNQIVDLIDNMNGLNGAL

Sequences:

>Translated_180_residues
MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMDFIDSDAVIEERTGADISWIFDLEGEDGFRKREERIINELTQMQGIVLST
GGGAVLSKENRNYLSARGIVIYLETTVEKQFQRTQRDKKRPLLQDAENPRQVLEDLAKIRNPLYEEIADITLPTDEQNAK
IMVNQIVDLIDNMNGLNGAL
>Mature_179_residues
AEKRNIFLVGPMGAGKSTIGRQLAQQLNMDFIDSDAVIEERTGADISWIFDLEGEDGFRKREERIINELTQMQGIVLSTG
GGAVLSKENRNYLSARGIVIYLETTVEKQFQRTQRDKKRPLLQDAENPRQVLEDLAKIRNPLYEEIADITLPTDEQNAKI
MVNQIVDLIDNMNGLNGAL

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=172, Percent_Identity=72.0930232558139, Blast_Score=265, Evalue=1e-72,
Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=32.7160493827161, Blast_Score=88, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=126, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20292; Mature: 20161

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMDFIDSDAVIEERTGADISWIFDLEGEDGFR
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCHH
KREERIINELTQMQGIVLSTGGGAVLSKENRNYLSARGIVIYLETTVEKQFQRTQRDKKR
HHHHHHHHHHHHHCCEEEECCCCEEEECCCCCEEECCCEEEEEEHHHHHHHHHHHHHHCC
PLLQDAENPRQVLEDLAKIRNPLYEEIADITLPTDEQNAKIMVNQIVDLIDNMNGLNGAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AEKRNIFLVGPMGAGKSTIGRQLAQQLNMDFIDSDAVIEERTGADISWIFDLEGEDGFR
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCHH
KREERIINELTQMQGIVLSTGGGAVLSKENRNYLSARGIVIYLETTVEKQFQRTQRDKKR
HHHHHHHHHHHHHCCEEEECCCCEEEECCCCCEEECCCEEEEEEHHHHHHHHHHHHHHCC
PLLQDAENPRQVLEDLAKIRNPLYEEIADITLPTDEQNAKIMVNQIVDLIDNMNGLNGAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA