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The map label for this gene is znuA [H]

Identifier: 148827261

GI number: 148827261

Start: 589929

End: 591032

Strand: Direct

Name: znuA [H]

Synonym: CGSHiGG_03175

Alternate gene names: 148827261

Gene position: 589929-591032 (Clockwise)

Preceding gene: 148827260

Following gene: 148827264

Centisome position: 31.26

GC content: 37.41

Gene sequence:

>1104_bases
ATGAAAAAACTTTTAAAAATTAGTGCCGTTTCTGCCGCACTTTTAAGTGCGCCAATGATGGCGAATGCCGATGTATTAGC
ATCAGTAAAACCTTTAGGCTTTATTGTTTCATCTATTGCAGATGGCGTAACTGGTACACAAGTCCTTGTTCCTGCAGGCG
CCTCTCCGCATGATTACAATTTGAAATTATCTGATATTCAAAAAGTAAAATCTGCAGATTTAGTTGTATGGATTGGTGAA
GACATTGATTCATTCTTAGACAAACCAATTAGCCAAATTGAACGTAAAAAAGTGATTACCATTGCCGATCTTGCGGATGT
AAAACCTTTATTAAGTAAAGCTCACCATGAGCATTTCCATGAAGATGGCGATCATGACCATAAGCACGAACACAAACATG
ATCATAAACACGACCATGACCATGATCATGATCATAAACACGACCATGACCATGATCATAAACACGAGCATAAACACGAC
CATGACCATGATCATAAACACGAGCATAAACACGACCACGACCATGATCATAAACACGAGCATAAACACGATCACGAACA
TCATGATCACGATCATCACGAGGGTTTAACCACAAACTGGCACGTTTGGTATTCTCCAGCTATCAGCAAAATTGTTGCAC
AAAAAGTAGCGGATAAATTAACTGCACAATTCCCAGATAAAAAAGCGTTAATTGCACAAAATCTTTCAGATTTTAACCGC
ACTTTGGCAGAACAAAGTGAAAAAATTACGGCACAACTTGCAAATGTTAAAGATAAAGGTTTCTACGTTTTCCACGATGC
TTATGGTTATTTCAACGATGCTTATGGGTTAAAACAAACGGGTTACTTTACCATCAATCCATTAGTAGCACCGGGTGCAA
AAACTTTAGCGCACATTAAAGAAGAAATTGATGAACATAAAGTAAATTGCTTATTCGCAGAGCCTCAATTTACGCCAAAA
GTGATTGAATCTTTAGCGAAAAATACGAAAGTCAATGTAGGACAACTCGACCCAATTGGCGATAAAGTTACTTTAGGTAA
AAATTCTTATGCAACATTCTTGCAATCTACTGCAGATAGCTACATGGAATGTTTAGCTAAATAA

Upstream 100 bases:

>100_bases
ATTTTCCCTCTTTTTACTATAAAATCGTTGCAATTTATATAAAAAGGCGTACTCTTTTTTCCCTTTGAGAATTACTACCA
ACAAGTAAGGAAACATAAAT

Downstream 100 bases:

>100_bases
ATCTTTCTAAAAACAATGACCGCATATAAAAGTGCGGTCATTTTCTTTTCTAAATTTGATATTTAGTTTTATCTCCAATA
TCAAAATGCAAAGGCATTCG

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKKLLKISAVSAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGE
DIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHKHEHKHDHKHDHDHDHDHKHDHDHDHKHEHKHD
HDHDHKHEHKHDHDHDHKHEHKHDHEHHDHDHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNR
TLAEQSEKITAQLANVKDKGFYVFHDAYGYFNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPK
VIESLAKNTKVNVGQLDPIGDKVTLGKNSYATFLQSTADSYMECLAK

Sequences:

>Translated_367_residues
MKKLLKISAVSAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGE
DIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHKHEHKHDHKHDHDHDHDHKHDHDHDHKHEHKHD
HDHDHKHEHKHDHDHDHKHEHKHDHEHHDHDHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNR
TLAEQSEKITAQLANVKDKGFYVFHDAYGYFNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPK
VIESLAKNTKVNVGQLDPIGDKVTLGKNSYATFLQSTADSYMECLAK
>Mature_367_residues
MKKLLKISAVSAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGE
DIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHKHEHKHDHKHDHDHDHDHKHDHDHDHKHEHKHD
HDHDHKHEHKHDHDHDHKHEHKHDHEHHDHDHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNR
TLAEQSEKITAQLANVKDKGFYVFHDAYGYFNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPK
VIESLAKNTKVNVGQLDPIGDKVTLGKNSYATFLQSTADSYMECLAK

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=180, Percent_Identity=45, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 41523; Mature: 41523

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLKISAVSAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYN
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LKLSDIQKVKSADLVVWIGEDIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFH
CCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHC
EDGDHDHKHEHKHDHKHDHDHDHDHKHDHDHDHKHEHKHDHDHDHKHEHKHDHDHDHKHE
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHCCCCCCCCCCHH
HKHDHEHHDHDHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNR
HCCCCCCCCCHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLAEQSEKITAQLANVKDKGFYVFHDAYGYFNDAYGLKQTGYFTINPLVAPGAKTLAHIK
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCCCCCEEECCCCCCCHHHHHHHH
EEIDEHKVNCLFAEPQFTPKVIESLAKNTKVNVGQLDPIGDKVTLGKNSYATFLQSTADS
HHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
YMECLAK
HHHHHCC
>Mature Secondary Structure
MKKLLKISAVSAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYN
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LKLSDIQKVKSADLVVWIGEDIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFH
CCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHC
EDGDHDHKHEHKHDHKHDHDHDHDHKHDHDHDHKHEHKHDHDHDHKHEHKHDHDHDHKHE
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHCCCCCCCCCCHH
HKHDHEHHDHDHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNR
HCCCCCCCCCHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLAEQSEKITAQLANVKDKGFYVFHDAYGYFNDAYGLKQTGYFTINPLVAPGAKTLAHIK
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCCCCCEEECCCCCCCHHHHHHHH
EEIDEHKVNCLFAEPQFTPKVIESLAKNTKVNVGQLDPIGDKVTLGKNSYATFLQSTADS
HHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
YMECLAK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]