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The map label for this gene is mltA [C]

Identifier: 148827260

GI number: 148827260

Start: 588965

End: 589750

Strand: Direct

Name: mltA [C]

Synonym: CGSHiGG_03170

Alternate gene names: 148827260

Gene position: 588965-589750 (Clockwise)

Preceding gene: 148827259

Following gene: 148827261

Centisome position: 31.21

GC content: 40.97

Gene sequence:

>786_bases
ATGGGTATTACGGTAATGGCTAGAATAGATAATTACGAACAACGCTTTGGTGGCATTGGGCGACTTTATACGCCTGATGG
CTTAGCACGCTTACGCCAAGCGCATATTTGCGTAATAGGCATTGGTGGCGTGGGTTCTTGGGTCGTGGAGGCCTTAGCAC
GTTCAGGTATTGGCGAACTCACATTAATTGATATGGATGATATTTGCGTCACAAATATCAATCGCCAACTTCCTGCGATG
AGCGGCACAATCGGCAAATTAAAAACTGAAGTCATGTCAGAGCGAGTAAAATTAATTAACTCAGAATGTACCGTCAATAT
TATTGATGATTTTATCTCGCCAGAGAATCAATCGGATTATCTCAACCGAGGCTATGACTACGTCATTGATGCCATTGACA
ATGTGAAAACTAAAGCGTCGCTGATTGCTTATTGTAAACGTAACAAAATTAATGTGATTACTATTGGCGGTGCTGGCGGT
CAAACTGATCCAACCCAAATTCAAATTGCCGATCTCAGTAAAACCATTCAAGATCCGCTGCTCGCCAAAGTGCGGTCAGT
TTTACGCAAGGATTACAATTTTAGCCAAAATCCAAAGCGCAAATTTAGCATCGATGCGGTATTTTCAACACAACCTTTAA
TATTCCCACAAATGACTGAAGACTGTTCTATTTCTGCCACAATGAATTGCGCAAACGGATTTGGTGCAGCCACGATGATT
ACGGCAACCTTTGGTTTTTTTGCCGTTTCTCGTGTAATAGATAAATTACTAAAGAAAAAATCTTAA

Upstream 100 bases:

>100_bases
ATGTAGGCGGCGCAGTGAAAGGTCATCACTTTGACTTATATCGTGGTATCGGTGCTAGAGCGGGACATATTGCAGGGCTT
TCAAAACACTACGGTAGAGT

Downstream 100 bases:

>100_bases
TCACCTCTTGAAAATGCACATTGACCATAAATGTGCATTTTTTTATTGAATGAAACCTATTGACTTTGAAAATGAAAAAT
TTTCCCTCTTTTTACTATAA

Product: murein transglycosylase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MGITVMARIDNYEQRFGGIGRLYTPDGLARLRQAHICVIGIGGVGSWVVEALARSGIGELTLIDMDDICVTNINRQLPAM
SGTIGKLKTEVMSERVKLINSECTVNIIDDFISPENQSDYLNRGYDYVIDAIDNVKTKASLIAYCKRNKINVITIGGAGG
QTDPTQIQIADLSKTIQDPLLAKVRSVLRKDYNFSQNPKRKFSIDAVFSTQPLIFPQMTEDCSISATMNCANGFGAATMI
TATFGFFAVSRVIDKLLKKKS

Sequences:

>Translated_261_residues
MGITVMARIDNYEQRFGGIGRLYTPDGLARLRQAHICVIGIGGVGSWVVEALARSGIGELTLIDMDDICVTNINRQLPAM
SGTIGKLKTEVMSERVKLINSECTVNIIDDFISPENQSDYLNRGYDYVIDAIDNVKTKASLIAYCKRNKINVITIGGAGG
QTDPTQIQIADLSKTIQDPLLAKVRSVLRKDYNFSQNPKRKFSIDAVFSTQPLIFPQMTEDCSISATMNCANGFGAATMI
TATFGFFAVSRVIDKLLKKKS
>Mature_260_residues
GITVMARIDNYEQRFGGIGRLYTPDGLARLRQAHICVIGIGGVGSWVVEALARSGIGELTLIDMDDICVTNINRQLPAMS
GTIGKLKTEVMSERVKLINSECTVNIIDDFISPENQSDYLNRGYDYVIDAIDNVKTKASLIAYCKRNKINVITIGGAGGQ
TDPTQIQIADLSKTIQDPLLAKVRSVLRKDYNFSQNPKRKFSIDAVFSTQPLIFPQMTEDCSISATMNCANGFGAATMIT
ATFGFFAVSRVIDKLLKKKS

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=259, Percent_Identity=56.7567567567568, Blast_Score=318, Evalue=2e-88,
Organism=Escherichia coli, GI87082356, Length=138, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787048, Length=136, Percent_Identity=27.2058823529412, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17540406, Length=112, Percent_Identity=30.3571428571429, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321790, Length=168, Percent_Identity=31.547619047619, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322825, Length=142, Percent_Identity=30.2816901408451, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582879, Length=131, Percent_Identity=32.0610687022901, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28602; Mature: 28471

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGITVMARIDNYEQRFGGIGRLYTPDGLARLRQAHICVIGIGGVGSWVVEALARSGIGEL
CCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCE
TLIDMDDICVTNINRQLPAMSGTIGKLKTEVMSERVKLINSECTVNIIDDFISPENQSDY
EEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCHH
LNRGYDYVIDAIDNVKTKASLIAYCKRNKINVITIGGAGGQTDPTQIQIADLSKTIQDPL
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHH
LAKVRSVLRKDYNFSQNPKRKFSIDAVFSTQPLIFPQMTEDCSISATMNCANGFGAATMI
HHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCEEEEECCCCCCHHHHH
TATFGFFAVSRVIDKLLKKKS
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GITVMARIDNYEQRFGGIGRLYTPDGLARLRQAHICVIGIGGVGSWVVEALARSGIGEL
CEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCE
TLIDMDDICVTNINRQLPAMSGTIGKLKTEVMSERVKLINSECTVNIIDDFISPENQSDY
EEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCHH
LNRGYDYVIDAIDNVKTKASLIAYCKRNKINVITIGGAGGQTDPTQIQIADLSKTIQDPL
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHH
LAKVRSVLRKDYNFSQNPKRKFSIDAVFSTQPLIFPQMTEDCSISATMNCANGFGAATMI
HHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCEEEEECCCCCCHHHHH
TATFGFFAVSRVIDKLLKKKS
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]