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The map label for this gene is fabI [H]

Identifier: 148827150

GI number: 148827150

Start: 434056

End: 434760

Strand: Reverse

Name: fabI [H]

Synonym: CGSHiGG_02410

Alternate gene names: 148827150

Gene position: 434760-434056 (Counterclockwise)

Preceding gene: 148827152

Following gene: 148827149

Centisome position: 23.04

GC content: 43.83

Gene sequence:

>705_bases
ATGGGTTTCTTAACAGGTAAACGCATTTTAGTCACTGGTCTTGCAAGCAATCGTTCCATCGCTTACGGGATCGCAAAATC
AATGAAAGAACAAGGTGCAGAACTTGCTTTCACTTATTTAAACGATAAATTACAACCGCGCGTAGAAGAATTTGCCAAAG
AATTTGGTTCTGATATCGTGCTTCCTTTAGATGTGGCAACCGATGAAAGCATCCAAAACTGCTTTGCAGAATTAAGTAAG
CGTTGGGATAAATTTGATGGTTTTATTCACGCAATCGCATTTGCACCAGGTGATCAATTAGACGGCGATTACGTAAACGC
GGCAACTCGTGAGGGCTATCGTATCGCTCACGATATTAGCGCATACAGCTTTGTTGCAATGGCACAAGCGGCACGTCCTT
ACTTAAATCCAAATGCAGCGTTATTAACCCTTTCTTATTTAGGTGCTGAGCGTGCAATTCCTAACTACAACGTAATGTGC
CTAGCGAAAGCCTCTCTTGAAGCTGCAACGCGCGTGATGGCTGCTGATTTAGGTAAAGAAGGTATTCGTGTGAATGCAAT
CTCTGCAGGCCCAATCCGCACCCTAGCCGCATCAGGCATTAAAAACTTCAAGAAAATGCTTTCCACCTTTGAAAAAACCG
CCGCATTACGTCGCACTGTCACTATCGAAGATGTGGGTAACTCAGCGGCATTTTTTATGCTCTGA

Upstream 100 bases:

>100_bases
AGTGCGGTTGGTTTTCTTAGAAAAATTGGTCGGCTTTGTACAAAGACAAATTTTCGCTTATACTACGCAAGTTTTTTACG
CTAACAACATAGGAAAAATT

Downstream 100 bases:

>100_bases
TTTAGCCTCTGGCATTACAGGCGAAATCGTTCACGTTGATGCAGGTTTCAGCATTACTGCAATGGGCGAATTAGGCGAAG
AATAATTTTTCTTACATTCT

Product: exoribonuclease II

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MGFLTGKRILVTGLASNRSIAYGIAKSMKEQGAELAFTYLNDKLQPRVEEFAKEFGSDIVLPLDVATDESIQNCFAELSK
RWDKFDGFIHAIAFAPGDQLDGDYVNAATREGYRIAHDISAYSFVAMAQAARPYLNPNAALLTLSYLGAERAIPNYNVMC
LAKASLEAATRVMAADLGKEGIRVNAISAGPIRTLAASGIKNFKKMLSTFEKTAALRRTVTIEDVGNSAAFFML

Sequences:

>Translated_234_residues
MGFLTGKRILVTGLASNRSIAYGIAKSMKEQGAELAFTYLNDKLQPRVEEFAKEFGSDIVLPLDVATDESIQNCFAELSK
RWDKFDGFIHAIAFAPGDQLDGDYVNAATREGYRIAHDISAYSFVAMAQAARPYLNPNAALLTLSYLGAERAIPNYNVMC
LAKASLEAATRVMAADLGKEGIRVNAISAGPIRTLAASGIKNFKKMLSTFEKTAALRRTVTIEDVGNSAAFFML
>Mature_233_residues
GFLTGKRILVTGLASNRSIAYGIAKSMKEQGAELAFTYLNDKLQPRVEEFAKEFGSDIVLPLDVATDESIQNCFAELSKR
WDKFDGFIHAIAFAPGDQLDGDYVNAATREGYRIAHDISAYSFVAMAQAARPYLNPNAALLTLSYLGAERAIPNYNVMCL
AKASLEAATRVMAADLGKEGIRVNAISAGPIRTLAASGIKNFKKMLSTFEKTAALRRTVTIEDVGNSAAFFML

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=232, Percent_Identity=75, Blast_Score=355, Evalue=1e-99,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 25406; Mature: 25275

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLTGKRILVTGLASNRSIAYGIAKSMKEQGAELAFTYLNDKLQPRVEEFAKEFGSDIV
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHEEEEHHCCCCCHHHHHHHHHHCCCEE
LPLDVATDESIQNCFAELSKRWDKFDGFIHAIAFAPGDQLDGDYVNAATREGYRIAHDIS
EEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHCCCEEEEHHHH
AYSFVAMAQAARPYLNPNAALLTLSYLGAERAIPNYNVMCLAKASLEAATRVMAADLGKE
HHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCC
GIRVNAISAGPIRTLAASGIKNFKKMLSTFEKTAALRRTVTIEDVGNSAAFFML
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEC
>Mature Secondary Structure 
GFLTGKRILVTGLASNRSIAYGIAKSMKEQGAELAFTYLNDKLQPRVEEFAKEFGSDIV
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHEEEEHHCCCCCHHHHHHHHHHCCCEE
LPLDVATDESIQNCFAELSKRWDKFDGFIHAIAFAPGDQLDGDYVNAATREGYRIAHDIS
EEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHCCCEEEEHHHH
AYSFVAMAQAARPYLNPNAALLTLSYLGAERAIPNYNVMCLAKASLEAATRVMAADLGKE
HHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCC
GIRVNAISAGPIRTLAASGIKNFKKMLSTFEKTAALRRTVTIEDVGNSAAFFML
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]