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The map label for this gene is fnr [H]

Identifier: 148826925

GI number: 148826925

Start: 171575

End: 172348

Strand: Direct

Name: fnr [H]

Synonym: CGSHiGG_00995

Alternate gene names: 148826925

Gene position: 171575-172348 (Clockwise)

Preceding gene: 148826921

Following gene: 148826926

Centisome position: 9.09

GC content: 34.63

Gene sequence:

>774_bases
ATGAAAAATTTCGTTGCGGGAGCTCAATCAGGGCGCAAAATTCAATCAGGCGGTTGTGCGATTCATTGTCAGGATTGCAG
TATTAGTCAGCTTTGTATTCCTTTTACCTTAAATGAACAAGAATTAGATCAGCTTGATAATATCATAGAGAGAAAAAAAC
CGATTCAAAAGTCTCAAGTATTATTTAAAGCAGGAGATTCTCTCAATTCAATTTATGCTATTCGTTCTGGCACAATAAAA
AGCTATACGATTAGTGAATCTGGCGAAGAACAAATTACTTCATTTCATTTGCCCGGTGACCTAGTTGGTTTTGATGCCAT
TACTCAAATGCAACACCCTAGTTTTGCGCAAGCTCTAGAAACGGCTATGGTATGTGAAATTCCTTTTGATATTTTAGATG
ATTTGGCAGGAAAAATGCCAAAACTACGCCAGCAAATTTTACGTTTGATGAGCAGTGAAATTAAAAGTGATCAAGAGATG
ATTTTATTGCTATCTAAAATGAATGCAGAAGAACGTTTGGCTGCTTTTATTCATAATCTTTCTAAACGCTATTCTGCTCG
AGGTTTTTCAGCAAAAGAATTTCGTTTAACAATGACACGTGGCGATATTGGTAATTATCTAGGTTTAACAGTAGAAACCA
TCAGCCGCTTATTAGGCCGCTTTCAAAAACTCGGCGTGATTAGTGTACAAGGCAAATATATTACAATCAATGATTTAAAT
GGTTTAATTGAATTAACTGGTACGAATAAAACAAAAATTACATTAGTTAAATAA

Upstream 100 bases:

>100_bases
AGCTGCCATAATGCTTTACTCTTCTTAATCTGACTAATTAGTGGTAGAATATTTGCGTTAGATCAATTTTACACTATTTT
TTTCAATATTTGAGGCGTAC

Downstream 100 bases:

>100_bases
ATTTAAGGCGTGAATATCACGCCTTTTTGTGCTTGATAAAAATAAATTTATCCAAATTAATCTTGTACCTTGCCATTTTT
GCTATTCTTTTTTATCCTAT

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIK
SYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEM
ILLLSKMNAEERLAAFIHNLSKRYSARGFSAKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
GLIELTGTNKTKITLVK

Sequences:

>Translated_257_residues
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIK
SYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEM
ILLLSKMNAEERLAAFIHNLSKRYSARGFSAKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
GLIELTGTNKTKITLVK
>Mature_257_residues
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIK
SYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEM
ILLLSKMNAEERLAAFIHNLSKRYSARGFSAKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
GLIELTGTNKTKITLVK

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=240, Percent_Identity=78.75, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28568; Mature: 28568

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQV
CCCCCCCCCCCCEECCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCHHHH
LFKAGDSLNSIYAIRSGTIKSYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALE
HHHCCCCCCEEEEEECCCEEEEEECCCCCHHHEEECCCCCHHHHHHHHHCCCCHHHHHHH
TAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEMILLLSKMNAEERLAAFIHNL
HHHHEECCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
SKRYSARGFSAKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
HHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCC
GLIELTGTNKTKITLVK
CEEEEECCCCEEEEEEC
>Mature Secondary Structure
MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQV
CCCCCCCCCCCCEECCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCHHHH
LFKAGDSLNSIYAIRSGTIKSYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALE
HHHCCCCCCEEEEEECCCEEEEEECCCCCHHHEEECCCCCHHHHHHHHHCCCCHHHHHHH
TAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEMILLLSKMNAEERLAAFIHNL
HHHHEECCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
SKRYSARGFSAKEFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLN
HHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCC
GLIELTGTNKTKITLVK
CEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]