Definition Haemophilus influenzae PittGG chromosome, complete genome.
Accession NC_009567
Length 1,887,192

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The map label for this gene is 148826815

Identifier: 148826815

GI number: 148826815

Start: 57940

End: 58035

Strand: Reverse

Name: 148826815

Synonym: CGSHiGG_00335

Alternate gene names: NA

Gene position: 58035-57940 (Counterclockwise)

Preceding gene: 148826816

Following gene: 148826813

Centisome position: 3.08

GC content: 46.88

Gene sequence:

>96_bases
ATGCTCAACGAAAACGACATCGAACAACTCACTCTTCAACGCCTGCAATCCCTCGGTTGGGAATATCGCTACGGTAAAGA
CTTGCCTGTTCATTAG

Upstream 100 bases:

>100_bases
TTCATGAAAAACACCTAAACTAAAACTACGCTCAAGACCATTCCCCTCTTTTGTAAAGAGGGGTTAGGGGAGATTTAAAC
CACACACTAAGGAACTCATC

Downstream 100 bases:

>100_bases
ATAACTGAGTTAGATCCTGTTGCAAGACTCGATGATGCGGAAAATTAACGCGGTAGGTTTCACAATATACTGGCTCTAAC
TCAATGGAAAGTAACTGGCG

Product: putative type I restriction enzyme HindVIIP R protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 31; Mature: 31

Protein sequence:

>31_residues
MLNENDIEQLTLQRLQSLGWEYRYGKDLPVH

Sequences:

>Translated_31_residues
MLNENDIEQLTLQRLQSLGWEYRYGKDLPVH
>Mature_31_residues
MLNENDIEQLTLQRLQSLGWEYRYGKDLPVH

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): T1RH_HAEIN (O05052)

Other databases:

- EMBL:   L42023
- PIR:   F64114
- RefSeq:   NP_439437.1
- ProteinModelPortal:   O05052
- REBASE:   1149
- GeneID:   950228
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1285
- NMPDR:   fig|71421.1.peg.1225
- TIGR:   HI_1285
- HOGENOM:   HBG492145
- OMA:   NKARRDL
- ProtClustDB:   CLSK808504
- BioCyc:   HINF71421:HI_1285-MONOMER
- BRENDA:   3.1.21.3
- InterPro:   IPR014001
- InterPro:   IPR021810
- InterPro:   IPR014021
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409
- SMART:   SM00487
- TIGRFAMs:   TIGR00348

Pfam domain/function: PF11867 DUF3387; PF04313 HSDR_N; PF04851 ResIII

EC number: =3.1.21.3

Molecular weight: Translated: 3760; Mature: 3760

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS51192 HELICASE_ATP_BIND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNENDIEQLTLQRLQSLGWEYRYGKDLPVH
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNENDIEQLTLQRLQSLGWEYRYGKDLPVH
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800