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The map label for this gene is htrB [H]

Identifier: 148826813

GI number: 148826813

Start: 55113

End: 56048

Strand: Reverse

Name: htrB [H]

Synonym: CGSHiGG_00325

Alternate gene names: 148826813

Gene position: 56048-55113 (Counterclockwise)

Preceding gene: 148826815

Following gene: 148826812

Centisome position: 2.97

GC content: 40.92

Gene sequence:

>936_bases
ATGAAAAACGAAAAACTCCCTCAATTTCAACCGCACTTTTTAGCCCCAAAATACTGGCTTTTTTGGCTAGGCGTGGCAAT
TTGGCGAAGTATTTTATGTCTTCCCTATCCTATTTTGCGCCATATTGGTCATGGTTTCGGTTGGCTATTTTCACATTTAA
AAGTAGGTAAACGTCGAGCTGCCATTGCACGCCGTAATCTTGAACTTTGTTTCCCAGACATGCCAGAGAATGAACGTGAG
GCGATTTTGCAAGAAAATCTCCGTTCAGTAGGCATGGCAATTATCGAAACTGGCATGGCTTGGTTTTGGTCGGATTCACG
TATCAAAAAATGGTCGAAAGTTGAAGGCTTACATTATCTAAAAGAAAATCAAAAAGATGGAATTGTTCTCGTCGGTGTTC
ATTTCTTAACGCTAGAACTTGGCGCACGCATCATTGGTTTACATCATCCTGGCATTGGTGTTTATCGTCCAAATGATAAT
CCTTTGCTTGATTGGCTACAAACGCAAGGTCGTTTACGCTCTAATAAAGATATGCTTGATCGTAAAGATTTACGCGGAAT
GATCAAAGCTTTACGCCACGAAGAAACCATTTGGTATGCGCCTGATCACGATTACGGCAGAAAAAATGCCGTTTTTGCAC
CATTTTTTGCGGTGCCCGATGCTTGCACAACCACTGGTAGTTATTATTTATTGAAATCCTCGCAAAACAGCAAAGTGATT
CCATTTGCGCCATTACGCAATAAAGATGGTTCAGGCTATACCGTGAGTATTTCAGCGCCTGTTGATTTTACGGATTTACA
AGATGAAACGGCGATTGCTACGCGAATGAATCAAATCGTTGAAAAGGAAATCATGAAGGGCATATCACAATATATGTGGC
TACATCGCCGTTTTAAAACACGTCCAGATGAAAAGACGCCTAGTTTATACGATTAA

Upstream 100 bases:

>100_bases
CCATTTTAAAATCTCTCTATTTGAATAACCAAAATTGTGGCGATTTTACCACAACTCAAATTTACGATAAACTACGCCCC
TAACTTACGTGGAAAGAACA

Downstream 100 bases:

>100_bases
AAGTGCGGTCGAATATCACCGCACTTTTTGATAGAATTTTCTCAAATTTAAAAATTAACGACTCATCTAACCATGACAAC
CAATTATTCAGCTCAAGAAA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: Heat shock protein B [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKNEKLPQFQPHFLAPKYWLFWLGVAIWRSILCLPYPILRHIGHGFGWLFSHLKVGKRRAAIARRNLELCFPDMPENERE
AILQENLRSVGMAIIETGMAWFWSDSRIKKWSKVEGLHYLKENQKDGIVLVGVHFLTLELGARIIGLHHPGIGVYRPNDN
PLLDWLQTQGRLRSNKDMLDRKDLRGMIKALRHEETIWYAPDHDYGRKNAVFAPFFAVPDACTTTGSYYLLKSSQNSKVI
PFAPLRNKDGSGYTVSISAPVDFTDLQDETAIATRMNQIVEKEIMKGISQYMWLHRRFKTRPDEKTPSLYD

Sequences:

>Translated_311_residues
MKNEKLPQFQPHFLAPKYWLFWLGVAIWRSILCLPYPILRHIGHGFGWLFSHLKVGKRRAAIARRNLELCFPDMPENERE
AILQENLRSVGMAIIETGMAWFWSDSRIKKWSKVEGLHYLKENQKDGIVLVGVHFLTLELGARIIGLHHPGIGVYRPNDN
PLLDWLQTQGRLRSNKDMLDRKDLRGMIKALRHEETIWYAPDHDYGRKNAVFAPFFAVPDACTTTGSYYLLKSSQNSKVI
PFAPLRNKDGSGYTVSISAPVDFTDLQDETAIATRMNQIVEKEIMKGISQYMWLHRRFKTRPDEKTPSLYD
>Mature_311_residues
MKNEKLPQFQPHFLAPKYWLFWLGVAIWRSILCLPYPILRHIGHGFGWLFSHLKVGKRRAAIARRNLELCFPDMPENERE
AILQENLRSVGMAIIETGMAWFWSDSRIKKWSKVEGLHYLKENQKDGIVLVGVHFLTLELGARIIGLHHPGIGVYRPNDN
PLLDWLQTQGRLRSNKDMLDRKDLRGMIKALRHEETIWYAPDHDYGRKNAVFAPFFAVPDACTTTGSYYLLKSSQNSKVI
PFAPLRNKDGSGYTVSISAPVDFTDLQDETAIATRMNQIVEKEIMKGISQYMWLHRRFKTRPDEKTPSLYD

Specific function: Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1787292, Length=307, Percent_Identity=55.700325732899, Blast_Score=347, Evalue=5e-97,
Organism=Escherichia coli, GI87082094, Length=305, Percent_Identity=48.5245901639344, Blast_Score=300, Evalue=6e-83,
Organism=Escherichia coli, GI1788161, Length=315, Percent_Identity=29.5238095238095, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 36038; Mature: 36038

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEKLPQFQPHFLAPKYWLFWLGVAIWRSILCLPYPILRHIGHGFGWLFSHLKVGKRRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHH
AIARRNLELCFPDMPENEREAILQENLRSVGMAIIETGMAWFWSDSRIKKWSKVEGLHYL
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCHHEEECCHHHHHHHHHHHHHHH
KENQKDGIVLVGVHFLTLELGARIIGLHHPGIGVYRPNDNPLLDWLQTQGRLRSNKDMLD
HCCCCCCEEEEHHHHHHHHHCCEEEEEECCCCEEECCCCCHHHHHHHHHCCCCCCHHHHH
RKDLRGMIKALRHEETIWYAPDHDYGRKNAVFAPFFAVPDACTTTGSYYLLKSSQNSKVI
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEECHHHCCCCCCCCCCEEEEECCCCCEEE
PFAPLRNKDGSGYTVSISAPVDFTDLQDETAIATRMNQIVEKEIMKGISQYMWLHRRFKT
EECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPDEKTPSLYD
CCCCCCCCCCC
>Mature Secondary Structure
MKNEKLPQFQPHFLAPKYWLFWLGVAIWRSILCLPYPILRHIGHGFGWLFSHLKVGKRRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHH
AIARRNLELCFPDMPENEREAILQENLRSVGMAIIETGMAWFWSDSRIKKWSKVEGLHYL
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCHHEEECCHHHHHHHHHHHHHHH
KENQKDGIVLVGVHFLTLELGARIIGLHHPGIGVYRPNDNPLLDWLQTQGRLRSNKDMLD
HCCCCCCEEEEHHHHHHHHHCCEEEEEECCCCEEECCCCCHHHHHHHHHCCCCCCHHHHH
RKDLRGMIKALRHEETIWYAPDHDYGRKNAVFAPFFAVPDACTTTGSYYLLKSSQNSKVI
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEECHHHCCCCCCCCCCEEEEECCCCCEEE
PFAPLRNKDGSGYTVSISAPVDFTDLQDETAIATRMNQIVEKEIMKGISQYMWLHRRFKT
EECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPDEKTPSLYD
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 7592970 [H]